Best TWAS P=2.61e-08 · Best GWAS P=1.24e-07 conditioned to 0.255
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | RP11-111A22.1 | 0.16 | 0.20 | enet | 19 | 0.21 | 3.1e-16 | 5.2 | -5.2 | 1.7e-07 | -0.94 | 0.01 | 0.99 | FALSE |
2 | YFS | Blood | GCHFR | 0.06 | 0.05 | enet | 23 | 0.05 | 4.0e-17 | 5.3 | -5.6 | 2.6e-08 | -0.84 | 0.02 | 0.98 | TRUE |
3 | The Cancer Genome Atlas | Glioblastoma Multiforme | C15orf57 | 0.18 | 0.14 | lasso | 3 | 0.10 | 4.9e-04 | 5.2 | -5.2 | 2.0e-07 | -0.99 | 0.01 | 0.98 | FALSE |