Best TWAS P=1.19e-07 · Best GWAS P=5.03e-07 conditioned to 0.544
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | FES | 0.28 | 0.17 | enet | 21 | 0.20 | 2.8e-15 | -4.8 | 5.2 | 2.0e-07 | -0.91 | 0.00 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FES | 0.06 | 0.05 | blup | 46 | 0.07 | 7.4e-14 | -4.8 | 5.3 | 1.2e-07 | -0.90 | 0.01 | 0.99 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | FES | 0.05 | 0.04 | lasso | 2 | 0.04 | 2.2e-05 | -4.8 | 5.3 | 1.4e-07 | -0.90 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FES | 0.12 | 0.09 | lasso | 5 | 0.08 | 4.1e-09 | -4.8 | 5.2 | 2.2e-07 | -0.81 | 0.01 | 0.99 | FALSE |