TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Father's age at death
:
←
chr15:90,730,363-92,135,418
Best TWAS P=1.19e-07 · Best GWAS P=5.03e-07 conditioned to 0.544
90.8M
91M
91.2M
91.4M
91.6M
91.8M
92M
92.2M
0
1
2
3
4
5
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
FES
0.06
0.05
blup
46
0.07
7.4e-14
-4.8
5.3
1.2e-07
-0.90
0.01
0.99
TRUE
3
The Cancer Genome Atlas
Lung Adenocarcinoma
FES
0.05
0.04
lasso
2
0.04
2.2e-05
-4.8
5.3
1.4e-07
-0.90
0.00
0.99
FALSE
1
GTEx
Cells Transformed fibroblasts
FES
0.28
0.17
enet
21
0.20
2.8e-15
-4.8
5.2
2.0e-07
-0.91
0.00
0.99
FALSE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
FES
0.12
0.09
lasso
5
0.08
4.1e-09
-4.8
5.2
2.2e-07
-0.81
0.01
0.99
FALSE