Best TWAS P=1.51e-08 · Best GWAS P=1.56e-09 conditioned to 0.0354
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | YLPM1 | 0.10 | 0.03 | lasso | 6 | 0.02 | 7.9e-03 | -5.3 | 5.5 | 4.3e-08 | -0.77 | 0.08 | 0.50 | FALSE |
| 2 | GTEx | Muscle Skeletal | DLST | 0.28 | 0.26 | enet | 23 | 0.26 | 2.1e-25 | -5.5 | -5.7 | 1.5e-08 | 0.93 | 0.08 | 0.92 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | RPS6KL1 | 0.08 | 0.08 | enet | 11 | 0.07 | 1.5e-04 | 4.5 | 5.5 | 3.6e-08 | -0.72 | 0.23 | 0.74 | FALSE |