Best TWAS P=1.03e-08 · Best GWAS P=1.42e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | FBXO31 | 0.08 | 0.09 | lasso | 5 | 0.08 | 4.0e-07 | 5.4 | 5.5 | 3.1e-08 | 0.96 | 0.01 | 0.99 | TRUE |
2 | NTR | Blood | MAP1LC3B | 0.05 | 0.02 | lasso | 8 | 0.03 | 1.6e-10 | 3.1 | -5.4 | 8.0e-08 | -0.73 | 0.02 | 0.98 | FALSE |
3 | YFS | Blood | MVD | 0.02 | 0.00 | bslmm | 333 | 0.01 | 2.2e-03 | 3.7 | -5.7 | 1.0e-08 | 0.09 | 0.01 | 0.13 | TRUE |