Best TWAS P=8.7e-08 · Best GWAS P=5.09e-06 conditioned to 0.435
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | B3GALTL | 0.37 | 0.17 | enet | 29 | 0.30 | 4.3e-17 | -4.6 | -5.2 | 2.3e-07 | 0.76 | 0.01 | 0.94 | FALSE |
2 | GTEx | Stomach | B3GALTL | 0.18 | 0.00 | lasso | 7 | 0.04 | 4.4e-03 | 4.0 | -5.3 | 1.4e-07 | 0.73 | 0.02 | 0.59 | FALSE |
3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | B3GALTL | 0.02 | 0.00 | blup | 105 | 0.01 | 1.9e-03 | -3.2 | -5.2 | 2.6e-07 | 0.79 | 0.02 | 0.54 | FALSE |
4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | B3GALTL | 0.09 | 0.05 | blup | 103 | 0.07 | 5.7e-08 | -4.3 | -5.4 | 8.7e-08 | 0.76 | 0.02 | 0.90 | TRUE |