Hub : Genes

B3GALTL

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2030 0.0400 4.8e-11 0.072 0.107 0.117 0.111 0.105 3.7e-09 6.4e-13 5.1e-14 2.0e-13 9.2e-13
2 GTEx Adipose Visceral Omentum 0.3170 0.0760 1.8e-05 0.010 NA 0.001 NA 0.043 8.8e-02 NA 2.9e-01 NA 2.6e-03
3 GTEx Artery Aorta 0.3700 0.0600 4.8e-12 0.168 NA 0.302 NA 0.240 1.4e-09 NA 4.3e-17 NA 2.0e-13
4 GTEx Artery Coronary 0.3200 0.0950 4.5e-04 0.057 NA 0.200 NA 0.171 5.4e-03 NA 2.5e-07 NA 2.1e-06
5 GTEx Artery Tibial 0.2155 0.0434 2.4e-09 0.050 NA 0.127 NA 0.143 9.1e-05 NA 3.6e-10 NA 2.6e-11
6 GTEx Brain Cortex 0.2520 0.0770 1.1e-03 0.132 NA 0.120 NA 0.152 1.7e-04 NA 3.5e-04 NA 5.4e-05
7 GTEx Breast Mammary Tissue 0.2060 0.0620 1.6e-03 -0.005 NA 0.043 NA 0.029 7.7e-01 NA 2.8e-03 NA 1.2e-02
8 GTEx Cells Transformed fibroblasts 0.3210 0.0480 1.0e-15 0.289 NA 0.288 NA 0.286 6.4e-22 NA 7.6e-22 NA 1.1e-21
9 GTEx Colon Sigmoid 0.3370 0.0780 1.1e-05 0.117 NA 0.135 NA 0.123 6.2e-05 NA 1.7e-05 NA 4.1e-05
10 GTEx Colon Transverse 0.1840 0.0560 4.0e-04 0.086 NA 0.056 NA 0.069 6.6e-05 NA 1.2e-03 NA 3.4e-04
11 GTEx Esophagus Mucosa 0.2530 0.0480 5.6e-11 0.187 NA 0.250 NA 0.260 1.3e-12 NA 8.6e-17 NA 1.8e-17
12 GTEx Esophagus Muscularis 0.2270 0.0510 2.0e-07 0.100 NA 0.086 NA 0.111 1.2e-06 NA 6.3e-06 NA 3.0e-07
13 GTEx Heart Atrial Appendage 0.2140 0.0750 2.3e-03 0.010 NA 0.042 NA 0.017 1.1e-01 NA 5.5e-03 NA 5.7e-02
14 GTEx Lung 0.2026 0.0477 7.2e-08 0.109 NA 0.144 NA 0.134 1.1e-08 NA 3.9e-11 NA 1.9e-10
15 GTEx Nerve Tibial 0.1781 0.0434 1.5e-06 0.105 NA 0.130 NA 0.133 7.7e-08 NA 1.8e-09 NA 1.1e-09
16 GTEx Skin Not Sun Exposed Suprapubic 0.2060 0.0700 1.2e-03 0.053 NA 0.038 NA 0.104 7.0e-04 NA 3.7e-03 NA 2.5e-06
17 GTEx Skin Sun Exposed Lower leg 0.1510 0.0390 1.1e-05 0.016 NA 0.019 NA 0.017 1.7e-02 NA 1.0e-02 NA 1.3e-02
18 GTEx Stomach 0.1800 0.0620 2.8e-03 0.003 NA 0.016 NA 0.042 2.2e-01 NA 5.8e-02 NA 4.4e-03
19 GTEx Testis 0.2860 0.0700 1.4e-05 0.151 NA 0.176 NA 0.178 3.2e-07 NA 2.9e-08 NA 2.6e-08
20 GTEx Thyroid 0.2450 0.0450 2.7e-11 0.272 NA 0.236 NA 0.245 6.3e-21 NA 5.0e-18 NA 9.9e-19
21 YFS Blood 0.3265 0.0294 0.0e+00 0.466 0.449 0.481 0.483 0.481 3.2e-174 1.1e-165 4.1e-182 5.8e-183 3.6e-182
22 TCGA Bladder Urothelial Carcinoma 0.0560 0.0320 1.9e-03 0.011 0.016 0.012 NA 0.002 3.8e-02 1.6e-02 3.1e-02 NA 2.0e-01
23 TCGA Breast Invasive Carcinoma 0.0210 0.0108 4.0e-04 -0.001 0.011 -0.001 NA 0.000 6.8e-01 1.9e-03 5.5e-01 NA 3.6e-01
24 TCGA Head and Neck Squamous Cell Carcinoma 0.0416 0.0200 2.5e-04 0.034 0.028 0.029 NA 0.032 1.0e-04 3.3e-04 3.1e-04 NA 1.6e-04
25 TCGA Kidney Renal Clear Cell Carcinoma 0.0918 0.0341 4.4e-08 0.046 0.067 0.062 NA 0.057 5.7e-06 5.7e-08 1.6e-07 NA 5.5e-07
26 TCGA Brain Lower Grade Glioma 0.0572 0.0290 8.1e-04 0.020 0.023 0.019 NA 0.026 2.0e-03 1.0e-03 3.0e-03 NA 5.3e-04
27 TCGA Lung Squamous Cell Carcinoma 0.0305 0.0147 4.0e-04 0.021 0.020 0.014 NA 0.015 1.7e-03 2.0e-03 8.4e-03 NA 6.6e-03
28 TCGA Pancreatic Adenocarcinoma 0.1370 0.0530 7.1e-06 0.117 0.154 0.146 NA 0.128 1.3e-05 5.2e-07 1.1e-06 NA 5.2e-06
29 TCGA Prostate Adenocarcinoma 0.0955 0.0341 7.8e-12 0.080 0.117 0.104 NA 0.105 1.0e-08 3.3e-12 5.8e-11 NA 4.9e-11
30 TCGA Thyroid Carcinoma 0.1380 0.0430 0.0e+00 0.172 0.202 0.187 NA 0.189 1.9e-16 2.2e-19 7.1e-18 NA 3.9e-18

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
Bipolar Disorder (2018) 2.0 3.2 6.7 2.0 1.6 1.9 1.4 2.1 1.9 1.8 1.5 1.8 1.4 1.9 1.9 0.2 1.6 2.3 2.6 1.8 1.9 1.7 1.6 -1.2 1.3 2.2 2.3 0.7 0.8 2.0 1.7 2.1 1.8
Bipolar Disorder or Schizophrenia 2.5 6.1 11.7 2.4 2.1 3.1 2.4 2.9 2.4 3.4 2.8 1.9 2.2 2.1 3.1 -0.2 2.4 2.5 2.5 2.8 3.0 2.2 1.9 -1.7 2.5 3.3 1.9 1.9 1.6 2.7 2.3 2.5 2.7
Depressed Affect (Nagel 2018) 5.8 12.3 20.4 -2.8 -2.9 -3.7 -3.5 -3.9 -3.5 -3.0 -3.9 -3.3 -3.6 -3.2 -4.0 -2.9 -3.2 -2.7 -3.3 -3.7 -4.1 -3.7 -3.4 3.0 -4.2 -3.8 -2.6 -4.5 -3.1 -3.6 -3.4 -3.4 -4.0
Depression (Nagel 2018) 5.5 8.3 14.5 -2.5 -3.0 -3.6 -3.1 -2.9 -3.1 -0.9 -3.2 -2.6 -3.1 -2.8 -3.3 -1.4 -3.2 -2.6 -1.9 -3.8 -3.1 -3.0 -2.9 2.6 -3.1 -2.8 -2.5 -3.1 -2.6 -3.0 -3.0 -2.9 -3.3
Intelligence (Savage-Jansen 2018) 1.5 4.5 11.8 2.2 0.7 2.9 1.9 3.4 1.6 2.6 2.4 2.8 1.3 1.7 2.2 2.2 1.3 1.8 1.5 2.4 3.1 2.3 1.3 -0.6 1.8 3.2 1.9 2.7 1.4 2.3 1.6 1.7 1.9
Neuroticism (Nagel 2018) 7.7 18.1 27.3 -4.1 -2.9 -5.1 -4.6 -5.2 -3.9 -4.5 -4.8 -4.4 -3.7 -3.5 -5.1 -4.0 -4.0 -3.2 -3.8 -4.9 -5.2 -4.4 -3.4 2.9 -4.6 -5.0 -2.9 -5.0 -3.5 -4.5 -4.1 -4.0 -4.7
Schizophrenia (2018) 1.5 3.2 8.2 1.4 1.4 2.5 1.9 2.1 1.6 2.9 2.4 0.9 1.6 1.2 2.4 -0.3 1.9 1.3 1.1 2.1 2.4 1.5 1.2 -1.2 2.2 2.4 0.5 1.9 1.4 1.9 1.5 1.6 2.1
Schizophrenia vs Biploar Disorder 2.2 2.9 8.7 -1.0 -1.8 -1.5 -1.6 -1.5 -2.2 -1.4 -1.3 -2.4 -1.6 -2.4 -1.6 -0.5 -1.5 -2.5 -1.1 -1.9 -0.9 -1.7 -1.9 1.7 -1.3 -2.1 -3.0 -0.7 -0.6 -1.8 -1.4 -2.0 -1.6
Worry (Nagel 2018) 7.3 15.4 22.7 -4.2 -2.4 -4.6 -4.1 -4.8 -3.7 -3.9 -4.7 -3.9 -3.5 -3.3 -4.7 -3.1 -3.9 -3.3 -3.9 -4.5 -4.7 -4.2 -3.0 2.5 -4.1 -4.6 -2.9 -4.3 -3.0 -4.4 -3.6 -3.9 -4.2
Alzheimer’s Disease (in mother) 0.6 0.6 1.6 -0.1 -1.2 -1.2 -0.5 -0.9 -0.8 -0.1 -0.6 -0.5 -0.9 -0.9 -0.7 -0.1 -0.5 -1.3 -0.5 -0.6 -0.9 -1.1 -0.9 0.7 -0.4 -0.7 -1.2 -0.0 -0.2 -0.9 -1.2 -1.1 -0.7
Alzheimer’s Disease (in father) 2.1 2.3 6.4 -1.8 -1.0 -0.8 -2.0 -1.5 -1.2 -0.5 -2.0 -0.3 -1.3 -1.0 -1.3 -1.3 -1.7 -1.0 -2.5 -1.6 -2.0 -1.8 -1.5 1.3 -0.9 -1.9 0.1 -1.2 -1.4 -1.9 -2.1 -2.0 -1.6
Alzheimer’s Disease (including proxy) 3.0 4.4 8.5 -1.8 -2.3 -2.0 -1.6 -2.2 -2.2 -0.9 -2.4 -1.3 -2.2 -1.9 -1.9 -0.8 -1.9 -2.3 -2.6 -1.8 -2.5 -2.6 -2.4 2.3 -1.7 -2.2 -1.3 -1.4 -1.4 -2.4 -2.9 -2.9 -2.3
Crohns Disease (2017) 0.2 0.3 2.7 0.7 -0.2 -0.8 0.6 0.2 -0.5 -0.0 0.4 0.3 -0.0 -0.9 0.1 -1.6 0.3 -0.9 -0.1 0.4 0.4 -0.0 -0.5 0.5 0.1 0.4 -1.4 0.2 0.7 0.2 0.2 -0.3 0.0
Irritable Bowel Disease (IBD) 1.1 2.5 10.4 -1.1 -1.0 -2.4 -1.1 -2.0 -1.7 -0.2 -0.9 -1.2 -1.0 -2.3 -1.8 -3.0 -1.0 -2.3 -1.5 -1.4 -1.6 -1.3 -1.4 1.0 -1.5 -1.2 -3.2 -1.2 -0.6 -1.4 -0.8 -1.1 -1.3
Ulcerative Colitis (UC) 3.0 5.6 13.2 -2.4 -1.5 -3.0 -2.4 -3.0 -2.5 -1.1 -1.9 -2.1 -1.9 -2.9 -2.7 -3.3 -2.0 -2.8 -2.4 -2.5 -2.7 -2.1 -2.1 1.6 -2.5 -2.3 -3.6 -2.2 -1.8 -2.4 -1.7 -1.7 -2.2
Major Depression (MDD) 8.8 10.6 17.3 -2.5 -2.4 -3.7 -4.2 -3.8 -3.7 -1.5 -3.4 -3.7 -3.0 -3.7 -3.6 -2.6 -2.8 -3.8 -3.2 -3.2 -3.5 -3.2 -3.1 2.7 -3.2 -3.8 -3.9 -3.2 -2.2 -3.5 -2.9 -3.3 -3.3
Reaction Time 1.7 3.3 7.9 2.5 2.1 1.8 1.7 1.8 1.6 -0.0 1.4 2.8 1.5 1.7 1.8 1.8 1.8 1.9 2.3 1.7 2.2 1.8 1.7 -1.2 1.4 1.9 1.7 1.5 2.0 1.8 1.8 1.8 1.8
Verbal and Numeric Reasoning (VNR) 2.1 5.1 12.0 0.8 1.1 3.5 1.6 3.3 1.9 3.0 2.0 3.2 1.9 2.3 2.3 3.3 0.8 2.2 1.7 2.2 2.8 2.1 2.0 -1.4 1.8 3.1 2.5 2.5 0.5 2.2 1.9 1.7 2.1
Breast Cancer 1.8 4.3 8.1 0.7 1.4 2.4 2.2 1.9 2.0 2.8 2.1 2.7 2.1 2.3 2.5 2.6 1.6 1.4 1.7 2.2 1.8 1.9 2.2 -2.0 2.4 2.4 1.8 2.6 1.4 1.9 1.9 1.4 2.3
Ovarian Cancer 0.3 0.3 1.8 -0.9 1.1 0.5 -0.6 0.1 -0.0 0.5 0.2 -0.1 0.4 -0.1 0.2 0.2 -0.6 -0.0 -0.6 0.3 0.2 0.5 0.4 -0.5 -0.7 0.4 -0.7 -0.5 -1.4 0.1 1.2 0.8 0.4
Prostate Cancer 0.4 0.6 6.2 0.5 -0.0 0.2 -0.2 -0.0 0.4 1.0 0.4 0.5 0.5 0.2 0.4 2.5 0.8 -0.3 0.6 0.6 0.1 0.6 0.7 -0.8 1.0 0.4 -0.4 1.4 1.4 0.1 0.4 0.3 0.6
Age at First Birth 1.5 2.3 5.9 1.7 0.8 1.3 2.4 1.9 1.6 0.6 1.6 1.0 1.4 1.9 1.6 0.7 1.6 1.6 1.1 1.4 2.1 1.3 1.2 -0.7 1.8 2.0 2.0 1.3 1.6 1.6 0.7 1.0 1.6
Bipolar Disorder (2011) 3.2 3.1 5.6 1.8 1.2 1.7 1.8 1.4 2.2 1.4 2.1 -0.0 2.1 2.1 1.8 0.1 2.1 2.2 1.1 1.9 1.6 1.8 1.8 -1.9 1.6 1.9 1.9 0.9 1.3 1.9 2.2 2.4 2.1
Body Mass Index (BMI) (2010) 0.2 0.2 0.9 0.6 0.3 -0.4 0.8 -0.3 0.4 -0.6 0.4 -0.8 0.7 0.3 0.1 0.4 0.4 0.1 -0.5 -0.2 -0.1 0.2 0.7 -0.9 0.5 -0.1 -0.4 -0.1 0.5 0.3 0.7 0.4 0.4
Coronary Artery Disease (CAD) 0.5 0.6 4.9 -0.6 1.4 0.4 -0.2 -0.4 0.4 2.2 0.2 -1.3 0.7 0.6 0.2 -1.4 -0.3 0.2 -0.6 -0.2 -0.3 0.3 1.0 -1.3 0.3 -0.2 0.1 -0.8 -1.5 0.0 0.4 0.2 0.3
Crohns Disease (2012) 0.4 0.6 4.0 0.3 -0.7 -0.7 -0.3 -0.5 -1.0 -0.2 -0.1 -0.2 -0.5 -1.6 -0.5 -1.2 -0.3 -1.5 -0.5 -0.4 -0.3 -0.8 -1.1 0.9 -0.3 -0.2 -2.0 -0.5 -0.4 -0.5 -0.6 -0.7 -0.6
Mean Putamen Volume 3.8 4.4 6.8 -1.3 -1.7 -1.8 -1.9 -1.7 -2.4 -1.9 -2.1 -2.2 -2.6 -2.6 -2.4 -1.7 -2.2 -1.9 -2.0 -2.4 -1.6 -2.3 -2.5 2.3 -2.5 -1.9 -2.2 -1.8 -1.8 -2.4 -2.1 -1.7 -2.2
Fasting Glucose 0.3 0.4 1.7 -0.7 -0.9 -0.6 -0.3 -0.5 -0.5 -1.3 -0.5 -0.3 -0.6 -0.4 -0.9 0.3 -0.7 -0.0 -0.4 -1.0 -0.7 -0.6 -0.3 0.0 -1.1 -0.7 -0.5 -1.0 -0.6 -0.3 -0.1 -0.3 -0.7
HbA1C 0.4 0.4 1.7 -0.2 -0.5 0.7 0.1 1.3 0.4 -0.5 0.7 -0.2 0.7 0.3 0.7 0.2 0.3 0.3 -0.5 0.8 1.3 0.5 0.4 -0.2 0.5 1.0 0.1 1.1 0.4 0.5 0.7 0.4 0.6
HDL Cholesterol 3.2 5.3 12.6 2.1 1.6 3.2 2.7 3.4 1.4 1.6 2.4 3.4 1.3 1.3 2.2 2.2 1.7 1.3 2.9 2.7 3.2 2.8 1.4 -0.6 2.1 2.7 1.4 3.6 2.3 1.9 1.9 1.7 2.2
LDL Cholesterol 0.1 0.1 0.8 -0.1 0.4 0.3 -0.4 0.5 -0.1 -0.9 0.0 0.2 -0.1 -0.3 0.0 0.4 -0.2 -0.1 0.6 0.3 0.5 0.4 -0.2 0.0 -0.1 0.4 -0.2 0.6 0.2 0.1 0.6 0.3 -0.0
Lupus 1.5 2.2 6.3 0.5 2.5 0.6 -0.0 0.8 2.0 0.8 1.3 1.1 2.5 1.9 1.7 0.8 1.0 1.3 0.4 0.8 1.0 1.2 2.4 -2.5 2.2 1.1 1.2 1.2 0.7 1.3 1.7 1.5 1.9
Neuroticism (2016) 4.1 5.9 16.3 -2.1 -1.4 -2.4 -3.0 -3.3 -2.4 -0.3 -2.1 -2.4 -1.8 -2.7 -2.6 -4.0 -2.0 -2.9 -2.0 -2.6 -3.2 -2.2 -1.7 1.0 -2.1 -2.9 -3.6 -2.1 -1.5 -2.6 -1.9 -2.1 -2.2
Primary Biliary Cirrhosis 0.4 0.6 4.4 0.3 -1.3 -0.7 -0.1 0.6 -0.8 -2.1 -0.5 -0.9 -1.1 -0.7 -0.6 -0.3 -0.4 -0.1 -0.5 -0.4 0.4 -0.6 -0.9 1.2 -0.6 -0.0 -0.3 -0.5 0.1 -0.7 -0.7 -0.8 -0.5
Rheumatoid Arthritis 1.1 1.5 4.3 -0.6 -0.9 -1.8 -0.6 -1.9 -1.1 -1.7 -1.2 -1.3 -0.8 -1.1 -1.5 -1.0 -1.2 -1.2 -0.5 -1.7 -1.3 -1.3 -0.7 0.1 -1.3 -2.1 -1.7 -1.3 -0.5 -1.4 -0.9 -0.8 -1.1
Schizophrenia (2014) 0.5 1.1 5.2 0.9 0.6 1.8 0.9 1.2 0.7 2.3 1.3 -0.3 0.9 0.4 1.4 -0.8 1.0 0.7 0.4 1.2 1.3 0.4 0.5 -0.6 1.0 1.5 0.0 0.4 0.5 1.0 1.2 0.8 1.2
Triglycerides 1.7 2.8 4.9 -1.8 -1.4 -1.7 -1.7 -2.2 -1.7 -0.4 -1.9 -1.8 -1.3 -1.7 -1.7 -0.1 -1.6 -2.0 -2.0 -1.6 -2.1 -1.8 -1.5 1.0 -1.7 -1.6 -1.9 -1.7 -1.6 -1.7 -1.6 -1.7 -1.8
Type 2 Diabetes (T2D) (2012) 0.5 0.6 3.0 -0.3 -0.2 -0.6 -0.3 -0.9 -0.7 -1.1 -0.8 0.5 -0.6 -0.7 -0.3 -1.7 -0.7 -1.2 -0.1 -0.3 -0.9 -0.7 -0.3 0.1 -0.5 -0.8 -1.5 -0.8 -1.1 -0.6 -0.0 -0.8 -0.6
Ulcerative Colitis 2.2 3.3 5.8 -2.1 -1.6 -2.3 -1.7 -2.3 -1.9 0.0 -1.3 -2.0 -1.4 -2.1 -1.9 -2.1 -1.4 -2.2 -1.7 -2.1 -2.3 -1.7 -1.7 1.4 -1.5 -1.7 -2.4 -1.5 -0.9 -1.8 -1.8 -1.6 -1.7
Blood Eosinophil Count 0.6 4.3 9.4 2.0 0.4 2.7 1.8 2.8 1.8 -0.5 2.5 1.7 1.2 1.6 2.3 2.2 1.9 2.2 3.1 2.9 2.4 2.5 1.6 -1.2 1.7 2.3 1.6 2.0 1.5 2.5 1.9 2.1 2.1
Blood Platelet Count 0.1 1.5 4.1 1.0 0.6 1.1 0.6 1.5 1.2 -0.2 1.1 1.5 1.6 1.2 1.5 0.3 0.9 1.0 1.1 1.6 1.6 1.4 1.3 -0.8 1.4 1.3 0.9 2.0 1.3 1.0 1.2 1.1 1.4
Blood Red Count 0.2 1.6 5.2 -1.3 -1.2 -1.8 -0.6 -1.7 -0.9 -1.4 -1.3 -2.3 -0.9 -0.5 -1.1 -0.4 -1.0 -0.9 -0.6 -1.1 -2.1 -1.1 -0.9 0.8 -1.3 -1.7 -0.3 -1.1 -1.1 -0.8 -1.5 -1.2 -1.7
Blood White Count 0.2 1.6 4.9 -0.6 -2.2 -1.2 -0.4 -1.4 -1.6 -1.2 -0.8 -1.2 -1.3 -1.9 -1.5 0.1 -0.9 -1.5 -0.6 -1.0 -1.2 -1.2 -1.3 1.2 -1.4 -1.7 -2.1 -1.0 -0.1 -1.1 -0.7 -1.1 -1.1
Heel T-Score 2.2 17.8 28.9 3.5 3.9 4.3 3.7 3.9 4.1 5.4 4.9 2.9 4.2 4.0 4.3 2.2 4.6 3.4 3.9 4.7 4.1 5.2 4.5 -4.4 4.4 4.7 2.8 3.8 4.1 4.8 4.8 4.5 5.0
BMI 0.1 0.5 1.7 0.5 0.2 -0.2 -1.0 -0.8 -0.7 -1.3 -0.3 -0.0 -0.4 -0.5 -0.5 0.1 -0.7 -0.5 -1.1 -0.8 -0.8 -0.5 -0.7 0.6 -1.2 -0.9 -0.6 -0.9 -1.0 -0.3 -0.6 -0.1 -0.8
Height 0.1 1.6 4.4 0.7 0.8 1.3 0.6 0.6 1.2 1.4 1.4 1.5 0.9 1.0 1.1 0.5 1.4 1.3 2.1 1.7 0.8 1.9 1.0 -1.3 0.8 0.8 1.0 1.0 0.7 1.4 1.9 1.7 1.3
Waist Hip Ratio (WHR) 0.2 0.8 2.4 -0.3 -0.2 -1.5 -0.7 -1.1 -0.6 -1.2 -0.6 -0.7 -0.4 -1.1 -1.0 -1.1 -0.6 -0.4 -0.7 -0.7 -1.0 -1.1 -0.6 0.2 -1.0 -1.4 -1.6 -1.3 -0.9 -0.7 0.2 -0.3 -0.7
Systolic Blood Pressure 1.4 7.1 18.6 -2.2 -0.7 -3.2 -3.3 -3.7 -1.9 -1.1 -3.2 -3.0 -1.9 -2.1 -2.9 -1.7 -2.3 -1.7 -4.3 -2.9 -3.4 -3.3 -1.9 1.2 -2.8 -3.3 -1.6 -3.7 -2.4 -2.7 -2.2 -2.2 -2.9
Smoking Status 0.7 1.6 3.7 -0.8 -0.2 -1.4 -1.9 -1.5 -1.2 -0.9 -1.6 -1.3 -1.2 -1.2 -1.3 -0.3 -1.2 -1.0 -1.2 -1.9 -1.5 -1.6 -0.7 0.3 -1.1 -1.4 -1.5 -1.5 -0.8 -1.5 -1.1 -1.2 -1.1
Allergy or Eczema 0.6 1.6 4.5 0.8 1.4 0.9 2.1 1.8 1.3 0.8 1.3 0.9 1.5 1.5 1.1 1.5 0.5 1.4 0.4 0.9 1.4 1.1 1.7 -1.7 1.2 1.8 1.0 0.7 0.3 1.5 0.9 1.3 1.5
Cardiovascular Disease 0.9 3.1 8.6 -0.3 0.0 -1.4 -2.8 -2.4 -1.4 -2.9 -1.5 -1.4 -1.1 -1.6 -2.3 -0.3 -1.4 -0.9 -2.0 -2.5 -1.9 -1.8 -1.5 0.8 -2.8 -2.3 -1.9 -2.4 -1.4 -1.5 -0.7 -0.3 -1.9
Hypothyroidism (self reported) 0.1 0.2 1.3 0.6 -0.8 -0.3 0.6 0.6 -0.1 -0.7 0.2 0.1 -0.5 -0.0 -0.0 -0.1 0.6 0.3 -0.0 -0.4 0.4 0.0 -0.4 0.5 0.2 0.0 0.1 0.3 1.1 0.0 -0.2 0.1 -0.1
Respiratory disease 0.6 1.2 4.3 -0.6 -1.5 -0.9 -0.2 -0.0 -1.4 -1.9 -0.5 -0.1 -1.6 -1.4 -1.1 -1.2 -1.0 -1.1 -0.1 -0.9 -0.4 -1.0 -1.6 2.1 -1.0 -0.5 -1.1 -0.8 -0.3 -0.9 -1.5 -1.3 -1.1
Type 2 Diabetes (T2D) (2018) 1.4 2.6 5.5 -1.7 -1.2 -1.6 -1.5 -1.5 -1.8 -1.0 -1.4 -1.5 -1.4 -1.9 -1.9 -1.3 -1.6 -1.5 -1.9 -1.6 -1.5 -1.7 -1.8 1.6 -2.3 -1.5 -2.0 -1.8 -1.4 -1.5 -1.2 -1.0 -1.7
Lung FEV1/FVC ratio 0.3 1.8 4.6 0.9 -2.1 -1.5 -0.1 -0.7 -1.5 -1.6 -1.1 -1.2 -1.6 -1.5 -1.2 -1.3 -1.4 -1.5 -0.8 -1.2 -0.7 -1.1 -1.6 1.6 -1.5 -1.4 -1.4 -1.2 -0.4 -1.0 -1.8 -1.2 -1.5
Lung FVC 0.7 3.5 9.8 -0.3 2.2 0.9 1.2 0.7 2.3 2.2 2.0 0.9 2.3 2.2 1.3 -0.1 2.3 1.9 1.9 1.1 1.2 2.4 2.7 -3.1 1.9 2.1 1.4 1.1 1.4 1.7 2.1 2.7 2.3
Neuroticism 5.7 13.7 19.7 -2.7 -2.8 -4.2 -3.6 -4.4 -3.6 -4.1 -4.2 -4.0 -3.5 -3.4 -4.4 -2.5 -3.5 -3.0 -3.5 -4.3 -4.4 -3.9 -3.4 2.8 -4.0 -4.3 -2.9 -4.2 -2.7 -4.0 -3.7 -3.5 -4.0
Chronotype (morning person) 1.1 2.6 5.1 0.8 1.5 1.3 0.8 0.9 2.1 1.5 1.7 1.3 1.9 2.2 2.1 0.1 2.0 1.8 1.9 1.8 0.5 1.8 2.1 -2.1 2.2 1.5 2.0 1.2 0.8 1.8 1.0 1.8 1.6
Hair Pigment 0.0 0.7 2.3 -1.2 -0.7 -1.3 -1.2 -0.0 -0.8 -1.1 -0.6 -1.5 -0.4 -0.5 -0.9 -0.3 -1.5 -0.8 -1.2 -1.0 0.0 0.1 -0.2 0.3 -0.7 -0.4 -0.5 -0.1 -1.1 -0.7 -0.7 -0.3 -0.7
Tanning 0.1 0.9 2.8 1.2 0.7 1.7 1.1 1.4 0.4 0.6 0.8 1.0 0.8 0.3 0.6 1.1 0.4 0.2 0.9 1.3 1.5 0.9 0.4 -0.3 0.6 1.0 0.2 1.6 0.9 0.9 0.9 0.7 0.9
Hand grip strength (left) 0.7 1.9 5.9 -2.1 -1.0 -1.7 -0.9 -1.4 -1.0 -1.4 -1.7 -1.3 -1.3 -0.7 -1.5 -0.7 -1.3 -0.6 -0.9 -1.5 -1.7 -1.7 -1.0 0.6 -1.5 -1.6 -0.4 -2.4 -1.7 -1.1 -1.6 -1.1 -1.5
Number of treatments/medications taken 5.5 9.9 19.3 -3.6 -1.2 -3.7 -4.1 -4.4 -2.6 -2.5 -3.4 -1.6 -1.9 -2.4 -3.8 -2.5 -3.4 -2.2 -3.9 -3.9 -4.0 -3.4 -2.0 1.1 -3.6 -4.1 -2.7 -4.1 -3.5 -3.4 -2.2 -2.1 -3.0
Average weekly spirits intake 2.1 2.7 5.1 -0.9 -2.3 -2.0 -1.6 -1.5 -1.6 -2.0 -1.3 -0.5 -1.4 -1.9 -1.4 -1.5 -1.5 -1.8 -1.2 -1.6 -1.7 -1.7 -2.0 2.1 -1.3 -2.1 -1.5 -0.4 -0.9 -1.8 -2.1 -1.8 -1.8
Sensitivity / hurt feelings 4.5 7.7 14.6 -1.8 -2.8 -3.5 -2.8 -3.8 -2.6 -2.2 -2.9 -2.9 -2.3 -2.7 -3.2 -2.7 -1.9 -2.8 -2.0 -3.2 -3.8 -2.6 -2.3 1.9 -2.1 -3.8 -2.6 -2.9 -1.1 -3.0 -3.0 -2.9 -3.0
Frequency of depressed mood in last 2 weeks 6.8 9.6 13.5 -2.8 -3.1 -3.4 -3.2 -3.2 -3.0 -2.7 -3.5 -3.1 -3.0 -2.7 -3.3 -1.9 -3.1 -2.6 -2.7 -3.7 -3.3 -3.5 -3.0 2.8 -3.3 -3.1 -2.1 -3.6 -3.0 -3.1 -3.4 -3.2 -3.6
Hearing difficulty/problems: Yes 0.2 0.4 1.3 1.0 0.9 0.5 -0.1 0.1 0.5 -1.0 0.5 0.4 0.8 0.5 0.1 0.0 0.6 0.7 0.4 0.4 0.2 0.5 0.5 -0.7 0.1 0.1 0.4 0.7 1.1 0.4 0.8 1.0 0.5
Relative age of first facial hair 1.2 2.4 5.9 1.9 0.2 1.9 1.8 2.4 1.4 1.2 1.8 0.7 1.1 1.5 1.2 2.0 1.1 1.7 1.2 0.7 2.4 1.7 1.2 -1.0 1.7 1.9 1.7 1.4 1.6 1.6 1.1 1.5 1.5
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 2.2 -1.0 -0.2 -0.6 -0.3 -1.4 -0.8 -0.5 -0.3 0.5 -1.3 -0.8 -0.2 -0.7 0.4 -0.8 -0.4 0.2 -1.5 -0.6 -0.9 0.6 -0.9 -0.8 -0.8 -0.9 0.0 -0.6 -0.5 -0.6 -0.6
Ever used hormone-replacement therapy (HRT) 0.1 0.1 1.0 0.8 0.7 0.2 0.4 0.4 0.0 -1.0 -0.1 0.2 0.0 0.3 -0.3 0.3 -0.3 0.2 0.3 -0.4 0.3 -0.1 0.0 0.1 0.3 -0.0 0.5 0.3 0.5 0.0 -0.3 -0.4 -0.1
Ever had hysterectomy (womb removed) 0.2 0.3 1.4 0.1 0.2 -0.2 -1.0 -0.8 0.2 0.5 -0.1 0.5 0.3 0.3 -0.0 -1.2 -0.2 -0.2 0.3 -0.5 -0.9 0.2 0.6 -0.9 0.7 -0.7 0.2 0.1 -0.6 -0.3 -0.4 -0.1 -0.0
Systolic blood pressure, automated reading 1.6 4.7 13.0 -1.5 -0.5 -2.7 -2.8 -3.0 -1.7 -0.5 -2.6 -2.3 -1.4 -1.6 -2.2 -1.5 -1.9 -1.7 -3.6 -2.4 -2.8 -2.6 -1.5 1.0 -1.9 -2.7 -1.4 -2.7 -1.7 -2.3 -2.2 -2.2 -2.3
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.7 0.5 0.5 0.1 0.2 0.4 -0.1 -0.3 0.4 0.8 0.8 -0.2 -0.1 0.4 0.0 -0.1 0.0 0.2 0.5 0.3 0.4 -0.1 0.2 0.5 -0.7 0.7 0.7 0.2 0.6 0.3 0.4
Angina 1.0 1.3 4.0 -1.4 -0.4 -2.0 -2.0 -1.9 -1.1 -0.8 -0.7 -0.2 -0.3 -1.3 -1.9 -0.4 -1.0 -1.3 -0.2 -1.8 -1.3 -0.7 -0.5 0.1 -1.1 -1.7 -1.9 -0.5 -0.4 -1.3 -0.3 -0.2 -0.7
Medication for hormone replacement therapy 0.4 0.5 2.5 0.1 -1.4 -0.5 0.1 0.0 -0.4 -0.3 -0.5 0.7 -0.9 -0.5 -0.4 -1.6 -0.4 -0.4 0.7 -0.7 0.2 -0.8 -0.7 0.7 -0.0 -0.7 -0.4 -0.3 0.2 -0.9 -1.3 -0.8 -0.3
Vitamin and mineral supplements 0.3 0.3 1.1 0.1 -0.7 0.8 1.0 0.7 -0.2 0.6 -0.1 1.0 -0.9 0.1 0.5 0.4 0.4 0.4 0.4 0.7 0.3 -0.3 -0.9 1.1 -0.5 0.6 0.6 -0.5 -0.4 0.3 -0.1 -0.2 -0.3
Supplements: Zinc 0.6 0.6 5.0 0.3 0.8 -0.7 -0.3 0.0 0.9 -2.2 0.4 0.5 1.2 0.9 0.3 -0.7 0.2 0.9 -0.2 0.0 0.2 0.8 1.3 -1.1 0.8 -0.0 0.7 0.4 -0.0 0.5 0.5 1.0 0.5
Medication: Co-codamol 0.2 0.3 1.5 -0.2 -0.6 0.1 -0.9 -0.8 -0.4 0.4 0.0 -0.2 -0.4 -0.9 -0.7 -0.3 -0.2 -0.2 0.2 -0.5 -0.7 -0.2 -0.3 0.1 -0.9 -0.7 -1.2 -0.4 -0.4 -0.2 0.4 0.2 -0.5
Medication: Metformin 0.9 1.3 2.7 -0.4 -0.9 -1.1 -1.3 -1.2 -1.3 -1.6 -1.0 0.1 -0.9 -1.3 -1.4 -0.3 -0.9 -1.1 -1.3 -1.3 -1.2 -1.5 -1.3 1.2 -1.6 -0.9 -1.6 -1.2 -0.6 -1.4 -1.0 -0.7 -1.1
Diabetes (father) 0.3 0.4 1.0 0.5 0.7 0.8 -0.3 0.3 0.9 0.1 0.2 1.0 0.8 0.8 0.7 0.0 0.6 1.0 0.4 0.7 0.0 0.6 0.8 -0.6 0.5 0.5 0.8 0.3 0.4 0.1 0.9 0.5 0.7
Diabetes (mother) 2.0 2.5 4.0 -1.3 -1.4 -1.4 -1.8 -1.9 -1.7 -0.4 -1.6 -2.0 -1.7 -1.7 -1.4 -1.0 -0.9 -1.8 -1.6 -0.8 -1.4 -1.9 -1.8 1.5 -1.8 -1.8 -1.8 -1.7 -1.1 -1.8 -1.6 -1.4 -1.8
Severe depression (siblings) 0.1 0.2 1.0 1.0 0.1 0.6 -0.6 0.1 -0.4 -0.0 -0.4 0.2 -0.1 -0.4 -0.2 -1.0 -0.3 -0.3 -0.1 0.3 0.4 -0.1 -0.1 0.1 -0.0 0.4 -0.3 0.4 0.3 -0.7 -0.1 -0.3 -0.0
Pack years adult smoking proportion 0.5 0.8 2.8 0.5 -0.2 -1.1 -0.4 -0.2 -1.4 -0.8 -0.2 0.4 -1.7 -1.4 -0.8 0.4 -0.2 -1.4 -0.3 -0.6 -0.1 -0.4 -1.4 1.6 -0.8 0.1 -1.4 0.6 0.8 -1.1 -0.6 -0.9 -0.7
Impedance of leg (right) 0.3 1.4 4.8 0.8 -0.3 1.1 1.9 1.6 0.8 1.7 1.0 1.1 0.1 0.6 1.7 0.9 1.6 0.8 1.7 2.2 1.2 1.2 0.3 0.2 1.3 1.2 1.0 1.2 1.3 1.1 1.1 0.0 1.1
Leg fat-free mass (left) 0.0 0.2 2.0 -0.3 0.3 -0.3 -1.2 -0.4 -0.1 -1.4 0.1 -0.0 0.2 -0.1 -0.3 0.5 -0.5 0.0 -0.6 -0.3 -0.3 0.1 0.1 -0.2 -0.6 -0.3 -0.2 -0.2 -0.9 -0.0 0.1 0.6 -0.1
Trunk fat percentage 0.3 1.3 3.0 -1.5 -1.0 -1.3 -1.3 -1.4 -1.5 -1.0 -0.8 -0.8 -1.0 -1.3 -1.2 -0.6 -1.3 -1.7 -1.0 -0.8 -1.4 -0.4 -1.0 1.0 -1.2 -1.5 -1.4 -0.8 -0.9 -1.1 -0.6 -1.2 -1.1
Hand grip strength (right) 0.2 0.5 1.6 -1.3 -0.5 -0.4 -0.2 -0.2 -0.5 -1.3 -0.8 -0.8 -0.4 -0.3 -0.7 -0.4 -1.1 -0.2 -0.7 -0.8 -0.4 -0.7 -0.3 0.3 -0.8 -0.7 -0.3 -1.2 -1.1 -0.4 -0.5 -0.5 -0.6
Townsend deprivation index at recruitment 1.6 2.3 4.9 -1.3 -0.3 -1.7 -1.3 -1.5 -1.4 -2.2 -1.6 -1.4 -1.1 -1.3 -1.9 -1.3 -1.7 -0.9 -1.9 -2.0 -1.9 -1.5 -1.2 1.0 -1.7 -1.5 -1.0 -1.7 -1.5 -1.7 -1.3 -1.1 -1.3
Current tobacco smoking 1.2 1.9 4.6 -0.4 -0.9 -1.6 -1.2 -1.1 -1.8 -0.9 -1.3 -0.8 -2.0 -2.0 -1.5 0.5 -1.3 -2.1 -1.6 -1.2 -1.2 -1.1 -1.4 1.3 -0.9 -1.1 -2.1 -0.2 -0.2 -1.8 -1.4 -2.0 -1.2
Average weekly fortified wine intake 3.1 3.6 9.0 1.9 2.4 1.9 1.9 2.3 2.0 1.1 2.0 1.6 2.0 2.1 2.1 2.2 0.9 1.6 1.1 1.9 2.1 1.9 2.2 -1.9 2.2 1.9 1.8 3.0 1.3 1.8 1.4 1.4 1.9
Maternal smoking around birth 1.6 2.3 4.7 -1.7 -1.8 -1.8 -0.7 -1.5 -1.9 -0.6 -1.2 -1.7 -1.8 -1.9 -1.6 -0.6 -1.2 -1.9 -1.8 -1.5 -1.0 -1.3 -1.7 1.2 -1.7 -1.2 -2.2 -1.8 -1.0 -1.5 -1.5 -1.5 -1.6
Fed-up feelings 6.4 11.7 18.3 -2.8 -2.8 -3.5 -3.9 -4.0 -3.2 -3.5 -3.8 -2.7 -3.2 -3.1 -3.8 -3.4 -3.0 -2.6 -2.7 -3.8 -4.3 -3.8 -3.4 3.0 -3.7 -3.8 -2.3 -4.2 -3.0 -3.6 -3.6 -3.2 -3.9
Frequency of unenthusiasm / disinterest in last 2 weeks 6.1 8.2 15.8 -2.7 -2.8 -3.6 -2.7 -3.0 -2.8 -1.2 -3.2 -3.0 -2.7 -2.5 -3.6 -1.2 -3.1 -2.2 -2.9 -4.0 -3.1 -2.8 -2.6 2.3 -3.3 -2.8 -2.1 -3.2 -2.7 -3.1 -3.0 -2.5 -3.3
Relative age voice broke 0.6 1.0 2.7 1.6 -0.1 1.0 1.6 1.3 0.9 1.2 1.2 -0.2 1.1 0.9 0.8 0.7 0.6 0.8 0.3 0.1 1.2 0.8 1.0 -0.9 1.6 1.5 0.6 1.3 0.9 0.9 0.3 0.6 1.0
Taking other prescription medications 6.2 9.6 18.4 -3.7 -1.8 -3.8 -4.1 -4.3 -2.9 -2.2 -3.2 -2.0 -2.6 -3.0 -3.6 -2.3 -2.9 -2.9 -3.3 -3.7 -4.0 -3.1 -2.6 1.8 -3.2 -4.2 -2.9 -2.6 -2.1 -3.4 -2.6 -2.5 -3.4
Age when periods started (menarche) 0.1 0.1 1.3 -0.2 0.2 -0.2 -0.0 -0.1 -0.1 0.1 -0.0 0.6 -0.2 0.0 -0.3 -0.8 0.0 -0.2 1.2 0.1 -0.0 0.4 0.0 -0.3 -0.5 0.4 -0.1 -0.2 0.1 -0.1 0.3 0.5 0.2
Bilateral oophorectomy (both ovaries removed) 2.6 3.0 6.2 2.3 0.6 2.5 1.4 1.8 1.4 2.3 2.0 1.4 1.2 1.3 1.9 1.5 2.1 1.1 2.1 1.9 1.8 2.0 1.1 -0.8 1.7 2.1 1.3 1.9 2.1 1.7 1.5 1.5 1.7
Heel bone mineral density (BMD) T-score, automated (left) 2.4 5.5 10.8 2.0 1.5 2.9 2.1 2.9 1.9 3.3 2.8 2.0 1.8 1.9 2.5 2.0 2.2 1.8 2.4 2.9 2.7 3.0 1.9 -1.7 2.3 2.8 1.6 2.7 2.3 2.6 2.2 2.2 2.4
Tinnitus: Yes, but not now, but have in the past 1.5 1.6 4.4 -1.3 -1.3 -1.0 -1.5 -0.7 -1.4 -1.0 -1.2 -0.4 -2.1 -1.5 -1.5 1.4 -1.1 -0.8 -1.5 -1.1 -1.2 -1.0 -1.6 1.3 -1.7 -1.1 -1.0 -1.0 -0.9 -1.4 -1.2 -0.8 -1.4
Qualifications: CSEs or equivalent 4.2 5.5 12.1 -3.5 -1.7 -1.9 -2.5 -2.7 -2.3 -0.5 -2.8 -2.4 -2.6 -2.1 -2.7 -1.6 -2.0 -1.6 -2.8 -2.6 -2.5 -2.4 -2.0 1.4 -2.7 -2.9 -1.9 -3.4 -2.0 -2.8 -1.8 -2.1 -2.2
Serious illness, injury or assault to yourself 0.6 0.7 2.4 1.1 0.8 0.8 -0.5 0.7 0.3 -0.6 1.4 1.2 0.6 -0.2 0.7 0.9 0.6 0.0 0.3 0.9 0.7 0.6 0.5 -0.6 0.2 0.9 -1.1 1.6 0.8 0.5 1.2 1.0 1.0
High blood pressure 0.1 0.4 2.2 0.4 0.4 0.0 -1.0 -0.8 0.0 -1.5 -0.3 -0.1 0.2 0.0 -0.7 0.4 0.0 0.6 -1.0 -0.9 -0.4 -0.7 -0.2 -0.2 -1.3 -0.5 -0.1 -1.0 -0.1 -0.1 0.5 0.7 -0.4
Hayfever, allergic rhinitis or eczema 0.3 0.6 2.1 0.7 0.7 0.4 1.5 1.2 0.6 1.1 1.1 0.5 0.9 0.6 0.6 1.3 0.1 0.5 0.4 0.4 1.0 0.7 0.9 -1.1 0.7 1.0 -0.0 0.3 -0.0 0.9 0.5 0.7 1.0
Multivitamins +/- minerals 0.4 0.5 2.4 -0.1 0.5 -0.8 -1.3 -1.1 -0.2 0.1 0.0 -1.2 0.8 -0.7 -0.7 -1.3 -0.4 -0.7 -0.1 -0.9 -0.6 -0.2 0.5 -0.9 0.2 -1.2 -1.6 -0.4 0.1 -0.6 0.1 0.3 0.1
Stomach or abdominal pain in last month 5.0 6.2 9.7 -2.6 -2.7 -2.6 -3.0 -2.5 -2.6 -2.5 -2.7 -1.3 -2.8 -2.7 -3.1 -1.2 -2.6 -2.2 -1.6 -2.7 -2.5 -2.2 -2.6 2.3 -3.0 -2.8 -2.2 -2.5 -1.7 -2.8 -2.1 -2.2 -2.9
Supplements: Glucosamine 0.1 0.2 1.1 1.0 0.1 -0.3 -0.2 0.0 0.0 0.1 0.1 0.4 0.2 0.0 -0.1 0.3 0.0 -0.4 0.9 -0.3 0.3 0.5 0.1 0.2 0.5 -0.3 0.2 1.0 0.8 0.0 -0.6 0.0 -0.1
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 1.1 0.7 -0.0 0.3 -0.2 0.1 -0.3 -1.1 0.2 -0.5 -0.3 -0.5 -0.3 0.5 -0.1 0.1 -0.1 -0.0 -0.1 0.2 -0.5 0.6 -0.6 -0.4 -0.3 0.3 0.3 0.1 -0.0 0.2 -0.4
Medication: Atenolol 0.4 0.4 2.4 -0.9 0.5 -0.7 -1.5 -1.4 0.0 -0.6 -0.5 0.5 -0.0 -0.0 -0.5 -0.1 -0.2 -0.0 -0.0 -0.6 -1.6 -0.1 0.1 -0.4 -0.9 -1.4 -0.0 0.1 -0.2 -0.3 0.4 0.2 -0.5
Medication: Levothyroxine sodium 0.4 0.7 2.2 -0.4 -1.0 -0.8 -1.2 -0.7 -0.8 -0.7 -0.7 -0.6 -0.7 -0.9 -1.0 -1.0 -0.5 -0.7 -0.9 -1.5 -0.7 -0.8 -1.0 0.8 -0.6 -1.1 -0.8 -0.3 0.0 -1.0 -0.9 -0.4 -1.0
Sitting height 0.0 0.2 1.3 -0.1 0.4 0.3 -1.1 0.3 0.1 0.4 0.5 -0.2 0.5 -0.2 0.4 0.4 -0.1 0.0 0.2 1.0 0.4 0.4 0.2 -0.2 0.3 0.5 -0.3 0.7 -0.4 0.4 0.7 0.4 0.5
Chronic bronchitis/emphysema (father) 2.3 2.6 4.4 -1.8 -0.4 -2.0 -1.7 -1.6 -1.8 0.5 -1.7 -1.2 -1.6 -1.8 -2.1 -1.4 -1.6 -1.6 -1.8 -1.9 -1.5 -1.8 -1.5 1.1 -1.7 -2.0 -1.8 -2.0 -0.9 -1.9 -1.5 -1.5 -1.6
High blood pressure (mother) 0.8 1.1 2.2 -0.6 -0.5 -0.8 -1.5 -0.8 -1.3 -0.7 -1.0 -0.0 -1.2 -1.1 -1.3 0.7 -0.8 -0.9 -1.3 -1.2 -0.8 -1.4 -1.3 1.1 -1.4 -0.6 -1.3 -1.4 -0.3 -1.3 -0.8 -0.9 -0.9
Body mass index (BMI) 0.5 1.9 5.0 -0.9 -0.4 -1.6 -1.8 -1.8 -1.4 -2.2 -1.2 -1.5 -0.8 -1.2 -1.4 -0.5 -1.5 -1.5 -2.1 -1.6 -1.8 -1.1 -0.9 0.8 -1.4 -1.8 -1.4 -1.2 -1.2 -1.2 -1.2 -1.1 -1.4
Impedance of leg (left) 0.3 1.5 4.7 0.5 -0.1 1.1 1.9 1.6 0.8 2.1 1.1 1.4 0.2 0.6 1.7 0.8 1.5 0.7 1.9 2.2 1.4 1.4 0.4 -0.0 1.4 1.2 0.9 1.3 1.4 1.1 1.2 0.0 1.2
Leg predicted mass (left) 0.0 0.2 2.1 -0.3 0.3 -0.3 -1.3 -0.4 -0.1 -1.4 0.1 -0.0 0.2 -0.1 -0.3 0.5 -0.5 0.0 -0.6 -0.4 -0.3 0.0 0.1 -0.2 -0.6 -0.3 -0.2 -0.2 -0.9 -0.0 0.1 0.6 -0.1
Trunk fat mass 0.2 0.7 1.7 -1.1 -0.5 -1.0 -1.3 -1.1 -1.0 -1.3 -0.5 -0.4 -0.5 -0.9 -0.9 -0.3 -1.0 -1.2 -0.7 -0.6 -1.1 -0.1 -0.5 0.5 -0.9 -1.2 -1.1 -0.5 -0.9 -0.7 -0.3 -0.6 -0.7
Waist circumference 0.4 1.4 5.0 -0.4 -0.3 -1.3 -1.6 -1.3 -1.2 -2.2 -0.9 -1.0 -0.9 -1.1 -1.1 -0.1 -1.3 -1.1 -1.8 -1.2 -1.4 -1.0 -1.0 0.9 -1.4 -1.6 -1.2 -1.1 -1.3 -1.0 -0.8 -0.9 -1.3
Number of incorrect matches in round 1.1 1.8 5.1 -0.9 -0.6 -2.0 -1.9 -1.7 -1.1 -1.2 -1.4 -1.4 -0.8 -1.2 -1.9 -1.6 -1.3 -0.9 -0.7 -2.1 -1.8 -1.0 -0.5 0.4 -0.9 -2.3 -1.2 -1.7 -0.3 -1.3 -0.8 -0.9 -1.2
Past tobacco smoking 0.9 1.7 6.2 1.6 -0.1 1.1 1.9 1.7 0.6 1.7 1.5 1.4 0.4 0.4 0.8 1.9 1.3 0.2 1.0 1.2 1.8 1.6 0.2 0.2 1.5 1.3 0.5 2.5 2.4 1.0 0.7 0.5 0.9
Alcohol usually taken with meals 3.7 5.9 10.7 3.3 1.7 2.9 2.2 3.0 2.5 3.2 2.8 1.0 2.5 2.5 2.7 1.2 1.9 2.4 1.7 2.4 2.8 2.5 2.5 -2.4 2.3 3.0 2.0 1.9 1.2 2.7 2.0 2.7 2.8
Nervous feelings 7.0 13.0 20.7 -3.3 -2.4 -4.1 -3.3 -4.5 -3.4 -2.5 -4.3 -3.5 -3.4 -3.2 -4.1 -3.3 -2.9 -3.1 -3.8 -4.3 -4.6 -4.1 -3.3 2.9 -3.3 -4.5 -2.5 -3.6 -1.8 -4.0 -3.8 -4.2 -4.1
Frequency of tenseness / restlessness in last 2 weeks 15.0 23.4 34.3 -4.2 -3.9 -4.8 -5.6 -5.4 -5.0 -3.1 -5.1 -5.9 -4.5 -4.9 -5.5 -3.5 -4.7 -4.8 -4.3 -5.8 -5.4 -4.9 -4.6 3.9 -5.0 -5.4 -4.8 -5.3 -3.9 -5.1 -4.5 -4.5 -5.3
Hearing difficulty/problems with background noise 0.4 0.6 2.6 0.1 1.6 -0.4 -0.6 -0.2 1.0 -1.0 -0.2 -0.3 1.3 1.5 0.1 -0.0 -0.1 1.3 -0.7 -0.3 -0.1 0.0 1.4 -1.6 0.4 -0.1 1.3 -0.4 0.1 0.4 0.6 0.8 0.4
Hair/balding pattern: Pattern 2 0.7 0.9 3.9 -0.3 -0.3 -0.9 -0.7 -1.1 -0.9 1.0 -0.7 -0.6 -0.8 -1.2 -0.7 -1.8 -0.4 -1.5 -2.0 -0.6 -1.1 -0.6 -0.6 0.1 -0.3 -0.5 -1.7 -0.7 -0.1 -1.1 -0.6 -0.9 -0.4
Had menopause 0.6 0.7 2.6 1.6 1.0 0.9 1.1 0.9 0.6 -0.3 1.1 0.1 0.5 0.5 1.0 1.4 0.6 0.4 -0.0 0.9 0.8 1.1 0.5 -0.3 0.8 0.6 0.5 1.6 0.5 0.7 0.7 0.6 0.8
Had other major operations 0.5 0.6 1.8 0.9 -0.7 0.3 0.2 0.4 -1.0 1.2 0.1 0.6 -1.1 -1.3 -0.1 0.9 -0.3 -1.2 0.6 0.2 0.1 0.5 -0.9 1.2 0.0 -0.1 -1.2 1.4 0.7 -0.6 -0.5 -0.7 -0.4
Forced vital capacity (FVC) 1.0 4.0 8.2 0.0 2.1 1.3 1.7 1.5 2.5 1.7 2.2 2.0 2.2 2.4 1.7 -0.2 2.1 2.3 2.0 1.5 1.8 2.5 2.7 -2.9 2.3 2.4 2.0 1.6 1.3 1.9 1.7 2.4 2.4
Heel bone mineral density (BMD) T-score, automated (right) 2.5 5.7 13.4 2.1 1.4 2.9 2.4 3.1 2.0 3.7 2.6 1.7 1.7 2.0 2.6 2.3 2.3 2.1 2.6 2.9 2.9 2.7 1.6 -1.3 2.1 2.9 2.0 2.4 2.1 2.5 2.3 2.2 2.5
Ever unenthusiastic/disinterested for a whole week 2.6 3.2 7.5 -1.4 -2.7 -0.8 -1.3 -1.5 -2.1 -0.7 -1.5 -0.7 -2.2 -2.3 -1.6 -0.1 -1.5 -1.7 -0.2 -1.4 -1.6 -2.6 -2.7 2.7 -2.0 -1.8 -1.6 -1.7 -1.3 -1.5 -2.2 -2.2 -2.1
Qualifications: None of the above 7.1 15.3 26.9 -4.2 -2.2 -5.0 -4.6 -5.2 -3.9 -1.6 -4.2 -3.5 -3.3 -3.9 -4.2 -4.6 -3.6 -4.4 -3.5 -4.4 -5.0 -3.8 -2.8 2.0 -3.3 -4.7 -4.5 -4.0 -3.1 -4.3 -3.1 -3.8 -3.8
Financial difficulties in last 2 years 4.3 5.8 8.8 -2.7 -1.8 -2.3 -2.2 -2.3 -2.6 -2.2 -2.6 -1.9 -2.8 -2.6 -2.8 -1.7 -2.8 -2.3 -2.6 -3.0 -2.3 -2.3 -2.4 2.2 -2.7 -2.4 -2.3 -2.1 -2.0 -2.8 -2.2 -2.2 -2.5
Mouth/teeth dental problems 0.3 0.5 4.7 0.2 1.0 1.2 0.2 0.3 0.5 2.2 0.9 0.4 0.5 0.2 0.5 -0.3 0.4 0.3 0.4 1.0 0.4 0.7 0.5 -0.8 0.2 0.8 -0.1 0.2 -0.4 0.5 0.5 0.9 0.6
Heart attack 0.9 1.2 3.1 -1.7 -0.1 -1.4 -1.5 -1.8 -0.7 -0.1 -1.1 -0.8 -0.2 -0.7 -1.5 -0.9 -1.3 -0.7 -1.2 -1.5 -1.5 -1.2 -0.2 -0.1 -1.1 -1.5 -0.9 -1.4 -1.3 -1.3 -0.2 -0.4 -0.8
Allergy 0.1 0.2 1.2 -0.4 -0.2 0.1 -0.8 -1.1 0.2 -0.2 -0.9 -0.3 -0.0 0.3 0.2 -0.7 0.5 0.1 -0.5 0.3 -0.9 -0.6 -0.2 0.2 -0.2 -0.7 0.8 -0.2 0.1 -0.3 0.1 -0.4 -0.4
Pain all over the body in last month 3.1 3.3 6.1 -0.7 -1.6 -1.8 -2.1 -1.8 -2.1 -0.2 -1.6 -0.6 -2.2 -2.3 -1.4 -1.9 -1.0 -2.4 -1.0 -1.4 -1.6 -2.1 -2.4 2.3 -1.4 -2.0 -2.2 -1.8 -1.1 -1.8 -2.5 -2.3 -2.1
Diabetes (self-reported) 1.1 1.7 4.7 -0.3 -0.9 -1.0 -0.9 -1.2 -1.4 -2.2 -1.3 -0.9 -1.1 -1.3 -1.6 -0.6 -1.2 -0.9 -2.1 -1.5 -1.5 -1.6 -1.4 1.1 -1.9 -1.0 -1.4 -1.5 -0.6 -1.5 -1.2 -1.0 -1.3
Hayfever/allergic rhinitis (self-reported) 0.2 0.2 1.5 -0.2 0.3 -0.2 -0.5 0.2 0.3 1.1 0.1 0.4 0.3 0.5 0.4 0.4 -0.2 0.5 -0.1 0.3 -0.1 -0.2 0.4 -0.8 0.0 0.1 0.2 -0.9 -1.2 0.3 0.1 0.2 0.4
Medication: Ramipril 0.3 0.4 2.0 -1.4 -0.1 -0.3 -1.4 -1.1 -0.1 -0.4 -0.6 0.4 -0.0 -0.0 -0.2 0.5 0.1 0.0 -0.8 -0.2 -1.1 -0.4 -0.4 0.3 -0.7 -0.9 0.4 -0.8 -0.5 -0.4 -0.3 -0.3 -0.7
Medication: Simvastatin 0.4 0.5 2.9 -0.4 -0.0 -0.6 -1.7 -1.5 -0.2 -0.9 -0.3 -0.5 -0.1 -0.2 -0.8 0.7 0.1 0.1 -0.2 -0.2 -1.3 -0.3 -0.3 -0.2 -1.3 -1.1 -0.2 -1.3 -0.4 -0.1 0.6 0.7 -0.3
Fluid intelligence score 2.3 4.9 10.0 0.6 1.8 3.0 1.6 2.8 2.4 2.3 1.9 3.2 2.1 2.7 2.1 2.4 0.7 2.7 1.4 2.0 2.5 2.1 2.6 -2.3 1.7 2.8 2.7 1.5 -0.4 2.2 2.0 2.3 2.2
Illnesses of siblings 1.7 2.4 10.7 0.3 0.5 1.8 1.5 2.2 1.4 1.0 1.3 2.2 1.4 1.4 1.5 1.6 1.0 1.8 3.3 1.5 1.8 1.8 1.3 -0.9 1.0 1.6 1.7 1.3 0.8 1.8 1.6 1.5 1.2
Neuroticism score 7.3 15.2 22.7 -3.5 -2.9 -4.6 -3.6 -4.6 -3.6 -4.3 -4.5 -4.3 -3.6 -3.2 -4.7 -2.9 -3.6 -3.0 -4.0 -4.4 -4.8 -4.3 -3.4 2.9 -4.1 -4.5 -2.6 -4.7 -3.1 -4.2 -3.7 -3.8 -4.2
Weight 0.1 0.5 3.1 -0.4 -0.0 -0.7 -1.4 -0.8 -0.6 -1.8 -0.2 -0.2 -0.2 -0.5 -0.6 0.4 -0.8 -0.6 -1.0 -0.6 -0.8 -0.1 -0.3 0.3 -0.7 -0.8 -0.6 -0.3 -0.9 -0.4 -0.3 -0.2 -0.6
Impedance of arm (right) 0.3 1.4 4.2 -1.1 -2.1 -0.6 0.2 -0.4 -1.4 1.7 -0.9 -0.0 -1.9 -1.5 -0.9 -1.4 -0.6 -1.6 0.4 -0.2 -0.4 -0.6 -1.8 1.9 -0.9 -0.6 -0.9 -0.4 -0.1 -1.3 -1.0 -1.9 -1.2
Arm fat percentage (right) 0.6 2.5 4.3 -1.5 -0.9 -1.7 -1.9 -2.1 -1.8 -1.8 -1.4 -1.3 -1.2 -1.5 -1.7 -1.0 -1.8 -2.0 -1.8 -1.6 -2.0 -1.1 -1.2 1.1 -1.6 -2.0 -1.6 -1.3 -1.4 -1.6 -1.3 -1.6 -1.8
Trunk fat-free mass 0.2 1.2 3.5 1.0 1.6 0.7 -0.5 0.7 1.3 -1.5 1.2 1.0 1.4 1.1 1.0 1.1 0.8 1.5 0.3 0.9 0.8 1.1 1.4 -1.4 0.7 0.8 0.8 0.6 -0.1 1.2 1.2 1.9 1.2
Hip circumference 0.1 0.2 1.6 -0.4 0.6 -0.0 -1.1 -0.3 -0.4 -1.2 -0.1 -0.5 0.0 -0.2 -0.1 0.5 -0.6 -0.4 -1.3 -0.2 -0.5 0.2 0.1 0.0 -0.2 -0.3 -0.4 0.0 -0.6 -0.2 -0.1 -0.2 -0.2
Time employed in main current job 0.3 0.3 2.1 0.6 0.7 -0.0 0.4 -0.5 -0.2 1.4 0.4 -0.2 0.2 -0.4 0.5 0.1 0.5 -1.1 -0.0 0.4 -0.3 -0.1 -0.1 -0.1 0.8 -0.3 -0.9 1.1 1.1 0.3 -0.3 -0.5 -0.0
Alcohol intake versus 10 years previously 0.2 0.2 1.4 -0.9 0.5 0.1 -0.6 -0.3 -0.2 1.2 -0.0 0.5 0.3 -0.2 -0.4 1.2 -0.7 -0.1 -0.2 -0.4 -0.0 0.1 0.1 -0.3 -0.1 -0.0 -0.2 -0.3 -1.1 -0.2 -0.1 0.0 -0.1
Father’s age at death 0.8 1.0 2.5 1.1 0.8 1.5 1.2 0.9 1.0 1.1 1.2 -0.1 1.3 1.1 1.0 0.3 1.0 0.8 1.6 0.9 1.3 0.4 0.8 -0.8 0.9 0.9 0.7 0.6 1.1 1.4 0.8 1.2 1.0
Worrier / anxious feelings 8.3 15.7 22.4 -3.6 -3.2 -4.0 -3.7 -4.7 -4.2 -3.1 -4.4 -3.7 -4.2 -3.9 -4.4 -2.6 -3.5 -3.6 -3.6 -3.8 -4.7 -4.3 -4.0 3.6 -4.7 -4.6 -3.3 -4.6 -3.2 -4.3 -3.8 -3.9 -4.4
Frequency of tiredness / lethargy in last 2 weeks 7.6 12.4 16.8 -2.9 -3.5 -3.8 -3.9 -3.3 -3.9 -3.0 -3.8 -3.4 -3.8 -3.8 -4.1 -2.1 -3.3 -3.2 -3.5 -3.8 -3.5 -3.6 -3.7 3.6 -3.7 -3.5 -3.2 -3.1 -2.1 -3.9 -3.8 -3.5 -4.0
Falls in the last year 2.6 3.6 9.9 -1.4 -2.1 -1.9 -1.6 -1.9 -2.5 -2.0 -1.5 -0.9 -2.3 -2.9 -2.5 -0.2 -1.7 -2.6 -1.1 -1.7 -1.4 -1.1 -2.2 1.8 -2.5 -1.9 -3.2 -1.2 -0.8 -1.9 -0.9 -1.4 -2.0
Hair/balding pattern: Pattern 3 0.5 0.8 2.5 -0.8 -0.4 -1.3 -0.4 -1.3 -0.6 -1.5 -0.9 -0.5 -0.8 -0.4 -0.9 -1.0 -0.3 -0.1 -0.4 -0.6 -1.3 -1.2 -0.8 0.6 -1.3 -1.0 -0.3 -1.6 -0.9 -0.4 -0.8 -0.4 -1.0
Number of live births 2.4 3.4 8.3 -2.9 -0.8 -2.1 -2.4 -2.6 -1.3 0.3 -2.4 -2.3 -1.5 -0.9 -1.5 -2.3 -1.4 -1.1 -1.5 -1.7 -2.5 -1.9 -1.1 0.7 -1.5 -2.5 -0.6 -2.7 -2.2 -1.9 -1.4 -1.8 -1.9
Forced expiratory volume in 1-second (FEV1) 0.8 2.6 5.1 0.2 1.4 0.9 1.5 1.3 2.0 1.2 1.8 1.6 1.7 1.9 1.4 -0.6 1.8 1.8 1.5 1.2 1.6 2.1 2.1 -2.2 1.8 1.7 1.6 1.2 1.4 1.6 1.2 2.0 1.9
Pulse rate 3.0 5.0 9.7 -2.2 -1.4 -2.5 -1.8 -2.5 -2.3 -2.6 -2.6 -2.0 -2.2 -2.1 -2.5 -1.0 -2.2 -1.8 -2.5 -2.3 -3.1 -2.3 -2.2 2.0 -2.9 -2.2 -1.6 -2.1 -1.8 -2.4 -2.1 -1.9 -2.6
Happiness 0.3 0.4 1.7 0.3 1.0 0.5 0.9 0.4 0.5 0.1 0.8 0.6 0.2 0.1 0.2 1.1 0.6 1.1 0.4 0.4 0.5 0.5 0.2 -0.3 -0.0 0.4 0.1 0.5 0.7 0.6 1.0 1.3 0.5
Noisy workplace 6.9 8.6 18.0 -2.2 -1.8 -3.3 -3.9 -3.5 -3.3 -2.1 -3.0 -1.4 -2.8 -3.6 -3.8 -1.6 -3.0 -3.5 -1.8 -3.6 -3.5 -2.7 -2.6 2.0 -3.0 -3.2 -4.2 -2.2 -1.7 -3.5 -2.2 -2.5 -2.9
Qualifications: A levels/AS levels or equivalent 1.2 2.8 6.6 2.3 0.3 1.7 1.4 2.6 1.4 0.6 1.7 2.4 0.9 1.4 1.6 1.9 1.5 1.6 2.2 1.5 2.6 1.7 0.9 -0.5 1.8 2.0 1.5 1.6 1.8 1.9 1.1 1.3 1.6
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 3.5 -0.0 0.4 0.1 0.3 0.5 0.8 -1.5 -0.0 0.8 0.8 1.1 0.3 1.9 -0.3 1.2 0.5 0.1 0.4 0.4 1.0 -0.8 0.1 0.7 1.3 0.0 -0.8 0.7 0.8 0.7 0.4
Mouth/teeth dental problems: Dentures 0.6 1.1 2.4 -1.3 -0.6 -1.3 -0.9 -1.2 -1.3 -1.5 -1.1 -1.0 -0.7 -1.1 -1.0 -0.3 -1.1 -1.5 -0.5 -1.1 -0.9 -1.0 -0.7 0.8 -0.9 -1.0 -1.3 0.1 -0.5 -1.2 -1.1 -1.2 -1.1
Asthma 0.3 0.6 2.1 0.7 0.3 0.5 0.9 1.3 0.1 -0.5 1.2 1.5 -0.2 -0.1 0.6 -0.1 0.9 0.5 1.4 0.7 1.0 1.1 0.0 0.3 0.6 1.1 -0.1 0.3 0.8 0.7 0.1 0.5 0.7
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.3 1.4 0.8 -0.9 0.1 0.6 0.3 -0.3 -1.2 -0.3 -0.0 -0.9 -0.1 -0.0 0.2 0.2 0.1 -0.2 -0.4 0.2 -0.5 -0.8 1.2 0.1 0.1 0.6 -0.6 0.7 0.1 -1.0 -1.0 -0.5
Medication: Cholesterol lowering 0.5 0.7 4.1 -0.2 -0.0 -1.2 -1.2 -1.5 -0.7 -2.0 -0.7 0.3 -0.5 -0.6 -1.1 -0.9 -0.3 -0.6 -0.0 -0.7 -1.2 -0.6 -0.5 0.2 -1.1 -1.2 -0.8 -1.1 -0.4 -0.7 0.2 -0.1 -0.6
Depression (self-reported) 7.8 9.3 17.7 -1.4 -2.4 -2.5 -3.7 -3.1 -3.2 -2.8 -3.2 -4.2 -3.0 -3.3 -3.6 -2.3 -2.9 -2.4 -2.8 -3.5 -2.8 -3.6 -3.3 3.0 -3.6 -3.8 -2.8 -3.3 -2.0 -3.0 -2.5 -2.6 -3.4
Medication: Lansoprazole 3.5 4.0 9.8 -2.1 -1.6 -1.4 -3.1 -2.6 -2.1 -0.4 -1.7 -2.1 -1.5 -2.4 -2.4 -1.8 -2.1 -2.5 -2.1 -2.1 -2.2 -2.0 -1.5 0.7 -2.1 -1.8 -3.1 -1.4 -1.8 -2.3 -1.3 -1.3 -1.8
Prospective memory result 2.5 3.1 7.6 -1.3 -1.1 -2.1 -2.8 -2.6 -1.9 -1.4 -2.0 -0.6 -1.9 -1.9 -1.6 -1.2 -0.9 -2.2 -0.8 -1.4 -2.6 -1.4 -1.7 1.7 -1.4 -2.3 -1.7 -1.2 -0.7 -2.2 -1.7 -1.9 -1.9
Lung cancer (father) 0.2 0.2 1.7 -0.3 0.3 0.7 1.3 0.4 0.3 -0.4 0.4 -0.2 -0.3 0.2 0.8 0.4 0.5 0.3 -0.6 0.5 0.1 0.1 0.1 0.1 0.4 0.5 0.2 1.0 0.8 0.3 0.1 -0.2 0.5
Illnesses of mother 2.2 2.7 5.3 0.8 1.7 1.4 1.5 1.8 2.0 0.4 1.4 1.6 1.8 2.0 1.9 -0.3 1.0 1.8 1.5 1.8 1.7 2.0 2.0 -1.6 2.1 1.6 2.3 2.0 0.8 1.7 1.5 1.4 1.7
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.6 2.0 -0.4 1.0 0.2 0.1 0.2 0.9 0.7 0.6 0.9 0.7 0.9 0.3 -1.0 0.8 0.8 1.0 0.1 0.4 1.1 1.2 -1.4 0.7 0.8 0.6 -0.0 0.3 0.5 0.4 1.2 0.9
Pulse wave Arterial Stiffness index 0.2 0.2 1.4 0.6 -0.0 0.6 -0.9 0.1 -0.4 -0.3 0.5 0.5 -0.3 -0.7 -0.1 0.6 -0.0 -0.6 0.4 0.0 0.3 0.5 -0.2 0.2 -0.1 0.3 -1.2 1.1 0.4 -0.1 0.0 0.5 0.1
Impedance of arm (left) 0.2 0.7 2.0 -1.3 -1.4 -0.5 0.4 -0.2 -1.1 0.9 -0.6 -0.1 -1.4 -1.1 -0.8 -1.3 -0.6 -1.1 0.2 -0.2 -0.2 -0.3 -1.3 1.4 -0.7 -0.4 -0.7 -0.1 -0.1 -0.9 -0.5 -1.4 -0.8
Arm fat mass (right) 0.4 1.6 4.5 -1.0 -0.5 -1.5 -1.8 -1.7 -1.3 -2.1 -1.0 -1.1 -0.8 -1.1 -1.3 -0.7 -1.4 -1.4 -1.6 -1.3 -1.7 -0.8 -0.8 0.8 -1.3 -1.7 -1.3 -1.1 -1.2 -1.1 -1.0 -1.0 -1.3
Trunk predicted mass 0.2 1.4 3.8 1.1 1.6 0.8 -0.5 0.8 1.4 -1.5 1.3 1.0 1.6 1.2 1.1 1.1 0.9 1.5 0.4 0.9 0.9 1.2 1.4 -1.5 0.9 0.8 0.9 0.8 0.0 1.3 1.3 1.9 1.3
Standing height 0.3 2.7 5.9 1.1 0.7 1.6 0.5 2.0 1.6 0.7 1.9 2.4 1.3 1.3 1.7 1.5 1.3 1.8 2.3 2.2 2.0 2.1 1.3 -1.1 1.3 1.9 1.5 1.8 0.4 1.8 1.8 1.9 1.8
Length of working week for main job 0.6 0.7 2.1 1.2 0.6 1.1 0.9 1.2 0.5 0.9 1.0 1.4 0.5 0.3 0.5 0.5 0.6 0.4 0.7 0.1 1.1 0.9 0.3 -0.1 0.8 1.4 0.3 1.4 1.2 0.3 0.4 0.9 0.9
Exposure to tobacco smoke at home 0.2 0.2 1.6 1.3 -0.0 -0.3 0.6 -0.0 -0.1 -0.7 0.4 -0.1 -0.0 -0.5 -0.1 -0.3 0.5 0.2 0.1 -0.3 -0.1 0.3 -0.2 0.3 0.0 -0.2 -0.6 -0.0 1.0 0.3 0.3 0.4 0.1
Breastfed as a baby 5.2 6.5 14.0 3.0 2.1 2.0 1.7 2.1 2.7 1.4 2.7 2.0 3.1 2.4 3.0 1.1 2.9 1.9 3.1 3.0 2.0 3.0 2.6 -2.1 3.4 2.4 2.1 3.7 2.7 2.6 2.2 2.4 2.7
Tense / ‘highly strung’ 5.7 9.4 16.8 -3.0 -2.1 -3.4 -3.6 -3.5 -2.7 -3.4 -3.7 -3.4 -2.6 -2.3 -3.6 -2.1 -2.9 -2.4 -3.0 -4.1 -3.6 -3.3 -2.5 2.0 -2.9 -3.8 -1.9 -3.1 -2.2 -3.4 -3.4 -3.0 -3.3
Seen doctor (GP) for nerves, anxiety, tension or depression 15.0 22.9 30.4 -3.3 -4.7 -5.1 -4.5 -4.9 -5.2 -4.0 -5.1 -3.9 -5.3 -5.0 -5.3 -3.0 -4.7 -4.6 -3.4 -5.2 -5.0 -5.5 -5.2 5.0 -5.2 -5.4 -4.3 -5.0 -3.3 -5.2 -5.3 -5.1 -5.4
Hair/balding pattern: Pattern 4 0.4 1.0 4.0 -0.2 0.6 1.1 0.2 0.6 1.3 0.4 0.8 -0.1 2.0 1.5 0.5 1.3 0.5 1.3 -0.1 0.4 1.1 0.7 1.4 -1.4 0.8 0.5 1.4 1.0 0.4 1.0 1.0 1.5 0.9
Birth weight of first child 0.1 0.1 0.7 0.0 0.3 0.8 0.0 0.6 -0.3 0.8 0.3 0.2 -0.4 -0.4 0.4 -0.0 -0.2 -0.3 -0.1 0.3 0.4 0.3 -0.1 0.3 0.3 0.0 -0.3 -0.1 -0.5 0.2 0.0 -0.5 0.1
Peak expiratory flow (PEF) 0.2 0.4 1.1 -0.4 0.5 0.2 0.3 0.3 0.9 0.9 0.7 0.3 0.5 0.9 0.5 -0.9 0.9 1.0 0.9 0.7 0.4 0.7 0.8 -1.0 0.5 0.5 0.9 -0.1 0.3 0.6 0.2 0.9 0.7
Pulse wave reflection index 1.1 1.3 3.1 1.1 1.1 1.3 0.5 1.0 1.0 1.2 1.5 1.5 1.1 0.8 1.1 0.9 1.0 0.5 1.5 1.0 1.1 1.5 1.1 -1.1 1.5 1.3 0.3 1.7 0.7 1.1 0.6 1.3 1.2
Ever highly irritable/argumentative for 2 days 1.3 1.5 3.2 -1.7 0.5 -1.0 -1.3 -1.3 -1.0 -0.6 -1.3 -1.6 -0.9 -0.8 -1.4 0.3 -1.8 -1.0 -1.7 -1.4 -1.1 -1.5 -1.1 0.9 -1.1 -1.4 -0.6 -1.1 -1.7 -1.1 -1.5 -1.3 -1.4
Loud music exposure frequency 0.5 0.6 1.4 -1.1 -0.3 -1.0 -1.2 -0.9 -0.4 -0.1 -1.0 -1.0 -0.7 -0.4 -0.8 -0.6 -0.8 -0.3 0.3 -1.1 -1.0 -0.8 -0.2 -0.0 -0.6 -1.2 -0.2 -1.0 -0.7 -0.7 -0.5 -0.8 -0.8
Qualifications: O levels/GCSEs or equivalent 0.3 0.5 4.2 0.5 -1.3 0.4 0.6 0.9 -0.2 -2.0 -0.4 0.1 -0.7 -0.1 -0.4 0.1 -0.2 0.7 0.1 -0.4 0.5 -0.6 -1.1 1.5 -0.5 0.1 1.1 -0.6 0.1 0.0 -0.8 -0.5 -0.6
Mouth/teeth dental problems: Bleeding gums 0.8 1.0 3.6 -1.1 -0.6 -1.5 -1.1 -1.0 -0.6 -1.5 -1.2 -1.8 -0.6 -0.4 -1.1 -0.7 -0.9 -0.2 -1.9 -1.4 -1.0 -1.1 -0.4 0.2 -0.7 -1.2 -0.4 -1.5 0.1 -0.7 -0.3 -0.8 -0.8
Blood clot in the leg (DVT) 1.3 1.7 3.6 -1.7 -1.4 -1.6 -1.6 -1.1 -1.3 -0.7 -1.3 -1.6 -1.1 -1.2 -1.8 -1.1 -1.6 -1.3 -1.5 -1.9 -1.3 -0.7 -0.9 0.7 -1.2 -1.8 -1.0 -0.5 -0.5 -1.5 -1.1 -1.1 -1.4
Medication: Paracetamol 1.2 2.0 4.2 -2.0 -1.4 -1.3 -1.2 -1.0 -1.6 -1.9 -1.3 -0.5 -1.5 -1.3 -1.5 -1.0 -1.6 -1.1 -0.4 -1.3 -1.3 -1.3 -1.4 1.6 -1.9 -1.1 -1.0 -1.8 -2.1 -1.1 -1.3 -1.3 -1.6
Headache pain in last month 2.0 3.4 6.1 -2.0 -0.9 -2.5 -2.0 -2.0 -1.7 -1.7 -2.0 -1.7 -2.0 -1.6 -2.0 -1.8 -1.5 -1.3 -2.0 -2.2 -2.0 -2.0 -1.7 1.4 -1.8 -2.0 -1.3 -2.4 -1.3 -1.9 -2.2 -1.7 -2.0
Medication for cholesterol, blood pressure or diabetes 1.0 1.7 4.3 1.1 0.3 1.7 2.0 2.1 0.9 1.9 1.3 0.5 1.0 0.8 1.4 1.3 0.8 0.7 1.7 1.5 2.0 1.4 0.7 -0.2 1.7 1.6 0.9 2.0 1.3 1.3 0.4 0.4 1.0
Glaucoma (self-reported) 0.5 0.6 2.3 -1.3 -0.3 -1.5 0.0 -0.9 -0.7 -1.5 -0.7 -0.3 -0.3 -0.6 -0.6 -0.2 -0.7 -1.0 -0.4 -0.4 -1.1 -0.5 -0.4 0.7 -0.2 -0.6 -0.7 0.2 0.1 -0.7 -0.9 -1.0 -0.7
Gout (self-reported) 0.5 0.7 2.3 -1.1 -1.0 -0.1 -0.5 -0.5 -0.8 0.1 -0.8 -1.3 -0.4 -0.8 -0.7 -0.5 -1.1 -1.2 -1.5 -0.9 -0.4 -0.7 -0.8 0.8 -0.7 -0.7 -0.7 -0.7 -1.0 -0.3 -1.3 -0.8 -1.0
Hypothyroidism/myxoedema (self-reported) 0.1 0.2 1.8 1.0 -0.8 0.2 0.4 0.6 0.0 -0.5 0.3 0.5 -0.2 -0.1 0.2 -0.0 0.8 0.2 -0.1 -0.4 0.6 0.1 -0.4 0.5 0.5 0.1 0.1 0.6 1.3 -0.1 -0.3 0.2 -0.0
Medication: Amlodipine 1.3 1.9 6.9 -0.7 -0.4 -1.2 -1.8 -1.9 -1.3 -1.4 -1.5 0.3 -1.4 -1.2 -1.2 -0.7 -0.6 -0.9 -2.6 -0.9 -1.8 -1.7 -1.7 1.2 -1.7 -1.6 -0.9 -1.7 -0.8 -1.5 -1.2 -1.1 -1.4
Medication: Ventolin 100micrograms inhaler 0.7 0.9 2.4 -0.9 -0.5 -0.7 -0.8 -1.0 -1.1 0.4 -0.6 -0.2 -0.9 -1.3 -0.6 -1.0 -0.5 -1.2 0.2 -0.7 -1.2 -1.1 -1.0 0.8 -0.9 -0.8 -1.6 -1.4 -1.1 -0.8 -1.0 -0.9 -0.8
Birth weight 0.2 0.4 2.0 0.6 0.5 0.8 0.0 0.9 0.2 -0.2 0.2 0.8 -0.5 0.3 0.8 1.4 0.5 0.6 0.9 1.0 0.6 0.7 0.0 0.2 -0.2 1.0 0.7 -0.0 0.0 0.6 0.4 0.3 0.3
Chronic bronchitis/emphysema (mother) 2.2 2.6 5.5 -1.5 -1.2 -1.5 -1.9 -1.5 -2.0 -0.7 -1.4 -1.1 -1.5 -2.0 -2.1 -0.6 -1.8 -1.6 -0.7 -2.1 -1.2 -1.7 -1.5 1.1 -2.2 -1.8 -2.3 -2.1 -1.5 -1.6 -1.3 -1.2 -1.7
High blood pressure (siblings) 0.4 0.5 2.8 1.2 0.8 -0.2 0.3 -0.1 0.8 -0.5 0.3 -1.4 0.4 1.1 0.6 -0.5 0.7 1.0 -1.7 0.3 -0.1 -0.1 0.7 -1.0 0.3 0.1 0.9 -0.5 0.3 0.5 0.4 0.9 0.6
Forced vital capacity (FVC), Best measure 0.5 1.7 4.2 -0.3 2.0 0.9 0.4 0.7 1.5 1.4 1.2 1.5 1.3 1.6 1.0 -0.6 1.3 1.5 1.7 0.8 0.8 1.7 1.9 -2.1 1.3 1.6 1.2 0.6 0.4 1.1 1.0 1.8 1.5
Body fat percentage 0.2 1.0 2.4 -1.2 -0.7 -1.1 -1.2 -1.4 -1.2 -1.0 -0.7 -0.8 -0.8 -1.0 -0.9 -0.3 -1.0 -1.5 -1.1 -0.7 -1.4 -0.3 -0.7 0.8 -1.0 -1.4 -1.2 -0.5 -0.7 -0.9 -0.5 -1.0 -1.0
Leg fat percentage (right) 0.1 0.3 1.3 -0.1 -0.0 -0.6 -0.4 -0.9 -0.5 -1.1 -0.1 -0.6 -0.2 -0.3 0.0 0.4 -0.2 -0.8 -0.9 0.1 -1.1 0.1 -0.2 0.5 -0.1 -0.9 -0.4 0.0 -0.2 -0.1 -0.2 -0.7 -0.5
Arm fat-free mass (right) 0.3 1.5 4.3 0.9 1.6 0.7 -0.5 0.8 1.4 -1.4 1.3 1.1 1.6 1.2 1.1 1.6 0.8 1.6 0.4 0.9 0.9 1.3 1.6 -1.7 0.7 0.8 0.8 0.7 -0.0 1.3 1.6 2.1 1.4
Exposure to tobacco smoke outside home 4.0 5.3 11.1 -0.9 -2.6 -2.8 -0.5 -1.8 -2.6 -3.3 -1.9 -3.0 -2.5 -2.8 -2.7 -0.9 -2.1 -2.2 -2.9 -2.6 -1.9 -2.5 -2.6 2.5 -2.9 -2.3 -2.8 -1.5 -0.8 -2.0 -1.9 -2.0 -2.4
Comparative body size at age 10 3.3 9.2 12.7 2.7 3.3 2.7 3.3 3.2 3.2 -0.2 3.2 3.1 3.3 3.2 2.8 2.4 2.6 3.3 2.3 2.2 3.5 3.6 3.5 -3.2 3.1 3.5 2.6 2.9 2.8 3.0 3.2 3.5 3.5
Number of full brothers 2.2 2.8 7.3 -1.9 -1.0 -2.1 -2.2 -2.7 -1.5 -0.2 -1.8 -1.1 -1.4 -1.6 -1.5 -1.2 -1.1 -2.0 -1.6 -1.5 -2.6 -1.5 -1.2 0.8 -1.1 -2.3 -1.9 -1.2 -0.8 -2.2 -1.9 -1.8 -1.6
Worry too long after embarrassment 1.0 1.8 6.0 -1.9 -1.4 -1.6 -0.6 -2.4 -0.3 -2.4 -1.5 -1.0 -0.2 0.3 -1.2 -1.4 -0.6 -0.1 -1.5 -1.1 -2.4 -1.4 -0.3 -0.1 -1.2 -1.8 0.5 -2.2 -0.9 -0.9 -0.7 -0.8 -1.2
Seen a psychiatrist for nerves, anxiety, tension or depression 3.4 4.4 11.4 -0.8 -1.4 -1.5 -3.4 -2.0 -2.2 -1.5 -2.2 -2.7 -2.4 -2.3 -2.4 -0.3 -2.5 -1.8 -2.0 -2.4 -1.8 -2.3 -1.9 1.6 -2.4 -2.5 -2.2 -1.8 -2.0 -2.3 -1.8 -1.8 -2.3
Wheeze or whistling in the chest in last year 3.1 5.5 15.1 -2.4 -1.5 -2.9 -2.7 -2.6 -2.8 -1.4 -1.9 -1.4 -2.4 -3.1 -3.0 -0.5 -2.4 -3.2 -2.0 -2.9 -2.2 -1.9 -2.0 1.6 -2.5 -2.3 -3.9 -2.0 -1.8 -2.8 -1.9 -1.9 -2.1
Number of children fathered 0.5 0.6 2.3 -0.5 1.3 -0.0 -1.1 -0.8 0.8 1.4 0.5 -1.0 1.4 0.5 0.1 -0.8 0.1 0.2 -0.6 0.2 -0.4 0.4 1.1 -1.5 0.3 -0.2 -0.3 -0.1 -0.8 0.5 0.8 0.9 0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.9 1.0 4.7 -0.6 -2.2 -1.2 -0.7 -1.5 -0.6 1.8 -0.8 -0.7 -1.0 -0.7 -0.6 -0.6 0.1 -0.7 -0.5 -0.8 -1.4 -1.5 -0.9 0.3 -0.4 -1.3 -0.9 -1.4 0.0 -0.8 -1.0 -1.0 -0.6
Age at first live birth 2.8 5.0 10.4 2.3 2.5 2.2 2.3 1.7 2.5 3.2 2.2 2.6 2.4 2.5 2.4 1.4 2.2 2.0 2.4 2.2 1.6 2.2 2.4 -2.3 2.3 2.5 2.2 1.2 1.4 2.5 2.1 2.2 2.3
Pulse wave peak to peak time 0.2 0.3 1.7 -0.7 0.0 -0.6 0.8 -0.2 0.5 0.2 -0.6 -0.5 0.4 0.8 0.2 -0.7 0.0 0.8 -0.3 0.1 -0.4 -0.5 0.3 -0.3 0.1 -0.4 1.3 -1.1 -0.5 0.1 0.0 -0.4 -0.1
Health satisfaction 0.7 0.9 3.5 0.5 -0.6 -1.0 -0.5 -0.5 -1.2 -1.2 -0.1 -0.6 -1.7 -1.7 -0.9 -0.5 -0.1 -1.3 -0.8 -0.5 -0.4 -0.2 -1.4 1.3 -0.9 -1.0 -1.9 0.1 0.8 -0.8 -0.5 -0.8 -0.7
Shortness of breath walking on level ground 0.2 0.2 0.8 0.2 0.2 -0.7 0.1 0.1 -0.5 0.4 0.1 0.5 -0.9 -0.5 -0.3 0.8 0.4 -0.5 0.7 0.1 0.3 -0.3 -0.5 0.5 -0.0 0.2 -0.8 0.2 0.8 -0.3 -0.1 -0.6 -0.0
Qualifications: College or University degree 8.0 25.2 37.6 5.9 4.4 5.8 5.3 6.1 5.2 2.5 5.3 5.6 4.8 5.3 5.1 4.9 4.2 5.4 4.4 5.1 5.7 4.9 4.5 -3.7 4.8 6.0 5.2 5.0 3.7 5.5 4.3 5.1 5.2
Eye problems/disorders: None of the above 0.2 0.2 0.8 -0.1 -0.6 -0.1 -0.9 0.1 -0.6 -0.3 -0.3 -0.3 -0.5 -0.6 -0.8 0.5 -0.7 -0.2 0.1 -0.9 0.2 -0.3 -0.6 0.5 -0.6 -0.4 -0.2 -0.6 -0.5 -0.5 -0.3 -0.1 -0.4
Mouth/teeth dental problems: Loose teeth 0.4 0.4 5.5 -0.0 -1.0 -0.0 -0.1 0.2 0.3 -2.4 -0.4 0.0 -0.3 0.6 0.4 -0.1 -0.2 1.0 -0.6 -0.2 -0.2 -0.7 -0.2 0.5 -0.3 -0.3 1.3 -0.6 -0.8 0.1 -0.1 -0.3 -0.2
Emphysema/chronic bronchitis 0.5 0.6 2.6 -0.5 -0.5 -1.0 -0.5 -0.8 -1.0 0.3 -0.1 -0.0 -0.5 -1.2 -1.6 0.1 -0.9 -1.3 0.1 -1.1 -0.2 -0.4 -0.8 0.6 -1.2 -0.4 -1.6 -0.4 -0.3 -1.0 -0.1 -0.1 -0.6
Medication for pain relief, constipation, heartburn 1.6 2.8 5.6 1.7 1.2 1.8 1.5 2.0 1.8 1.4 1.5 0.9 1.7 1.7 1.9 1.4 1.4 1.5 1.9 1.7 1.7 2.0 1.6 -1.4 1.8 1.8 1.7 2.4 1.1 1.5 1.6 1.8 1.8
Neck or shoulder pain in last month 1.5 2.2 6.9 -1.0 -0.4 -2.6 -1.4 -1.9 -1.3 -2.1 -1.5 -1.8 -0.9 -1.3 -1.7 -1.8 -1.2 -1.1 -1.7 -1.9 -1.7 -1.9 -1.1 0.7 -1.3 -1.2 -1.5 -1.3 -0.9 -1.4 -1.2 -1.0 -1.4
Medication: Blood pressure 0.5 0.9 3.9 -1.1 0.3 -1.1 -2.0 -1.8 -0.4 -0.9 -0.9 0.1 -0.3 -0.3 -0.6 -0.6 -0.1 -0.3 -1.9 -1.0 -1.7 -1.1 -0.4 -0.1 -1.2 -1.1 -0.4 -1.4 -0.9 -0.9 -0.3 -0.1 -0.7
Angina (self-reported) 1.9 2.6 6.4 -1.8 -0.7 -2.4 -2.5 -2.4 -1.6 -1.0 -1.2 -0.7 -0.7 -1.8 -2.5 -0.9 -1.6 -1.9 -0.8 -2.3 -1.8 -1.2 -0.8 0.3 -1.6 -2.3 -2.5 -0.9 -0.8 -1.8 -0.7 -0.6 -1.2
Migraine (self-reported) 0.4 0.5 1.6 -1.0 1.3 0.4 0.2 0.0 0.6 -1.0 0.4 0.1 1.2 0.6 0.0 -1.2 -0.1 0.4 -0.2 0.2 0.4 0.7 1.1 -1.0 0.3 0.1 0.1 0.4 -0.1 0.6 1.1 0.8 0.6
Medication: Ibuprofen 1.0 1.2 3.9 0.1 -1.5 -0.4 0.0 -0.1 -1.0 -1.4 -1.3 -0.5 -1.5 -0.6 -0.8 -0.3 -0.8 -0.2 -0.9 -1.1 -0.4 -1.6 -1.6 2.0 -0.9 -0.5 0.4 -1.7 -0.5 -0.8 -1.6 -1.8 -1.3
Medication: Allopurinol 1.8 2.4 6.4 -1.8 -1.3 -1.1 -1.9 -1.4 -1.4 -0.5 -1.6 -2.2 -0.9 -1.5 -1.7 -0.4 -2.0 -1.5 -2.5 -1.8 -1.3 -1.7 -1.3 1.2 -1.4 -1.4 -1.5 -1.2 -1.7 -1.4 -1.7 -1.4 -1.6
Medication: Omeprazole 4.4 5.2 9.0 -2.7 -1.9 -2.8 -2.5 -3.0 -2.3 -0.2 -2.2 -1.4 -2.3 -2.2 -2.3 -2.5 -2.0 -2.3 -2.2 -2.0 -2.9 -2.3 -2.2 1.7 -2.9 -2.9 -2.2 -2.6 -2.1 -1.7 -1.7 -2.0 -2.7
Medication: Seretide 50 evohaler 0.3 0.4 1.8 -0.2 -0.7 -0.8 -0.5 -0.5 -0.5 0.2 0.3 -1.3 -0.4 -0.8 -0.6 -0.7 -0.4 -0.7 -1.0 -0.8 -0.3 -0.1 -0.3 0.2 -0.6 -0.7 -1.2 -0.3 -0.5 -0.3 -0.1 0.3 -0.2
Mean time to correctly identify matches 1.6 3.1 6.6 2.6 2.1 1.6 1.8 1.5 1.6 -0.1 1.5 2.5 1.6 1.7 1.7 1.6 1.6 1.6 2.1 1.6 1.8 1.8 1.7 -1.4 1.5 1.8 1.7 1.7 1.9 2.0 1.7 1.7 1.6
Heart disease (mother) 0.6 0.8 2.7 -0.7 -0.4 -0.9 -0.1 -1.1 -0.6 -1.3 -1.1 -1.6 -0.6 -0.3 -0.8 -1.2 -0.3 -0.5 -1.6 -1.0 -1.4 -0.8 -0.7 0.6 -0.5 -0.8 0.3 -0.6 0.3 -0.8 -0.9 -1.0 -0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.8 0.9 3.2 0.3 -0.7 -1.0 -1.0 -1.0 -0.7 -1.4 -1.0 -1.2 -0.9 -0.7 -1.1 -1.8 -0.5 -0.5 -0.6 -1.0 -0.9 -1.6 -1.0 0.5 -1.0 -1.1 -0.5 -0.8 0.0 -1.3 -0.8 -0.8 -0.9
Whole body fat mass 0.2 0.9 2.1 -0.9 -0.5 -1.1 -1.4 -1.4 -1.1 -1.4 -0.6 -0.7 -0.6 -0.9 -0.9 -0.4 -1.0 -1.2 -1.1 -0.8 -1.4 -0.3 -0.6 0.6 -1.0 -1.4 -1.1 -0.6 -0.9 -0.8 -0.4 -0.7 -0.9
Leg fat mass (right) 0.1 0.3 1.6 -0.4 0.2 -0.6 -1.0 -0.8 -0.4 -1.3 -0.1 -0.4 0.0 -0.3 -0.2 0.6 -0.5 -0.6 -0.8 -0.3 -0.9 0.0 0.0 0.1 -0.3 -0.8 -0.5 -0.1 -0.5 -0.1 0.1 -0.2 -0.3
Arm predicted mass (right) 0.3 1.6 4.6 0.9 1.7 0.6 -0.6 0.7 1.5 -1.2 1.3 1.1 1.8 1.3 1.1 1.5 0.9 1.6 0.4 0.9 0.9 1.3 1.7 -1.8 0.9 0.7 0.9 0.8 0.1 1.3 1.7 2.1 1.5
Pulse rate, automated reading 1.8 5.8 7.9 -2.0 -2.0 -2.5 -1.8 -2.1 -2.7 -2.7 -2.6 -1.5 -2.4 -2.6 -2.8 -1.8 -2.8 -2.4 -2.7 -2.5 -2.5 -2.7 -2.6 2.5 -2.8 -2.1 -2.3 -2.0 -1.8 -2.7 -2.2 -2.5 -2.6
Alcohol intake frequency. 4.2 9.7 17.4 -3.5 -2.7 -3.3 -4.1 -4.2 -3.1 -0.4 -3.2 -2.8 -2.9 -3.2 -3.5 -2.4 -2.5 -3.2 -2.9 -3.1 -3.8 -3.2 -2.9 2.2 -2.7 -3.8 -3.2 -3.1 -2.2 -3.6 -2.9 -3.2 -3.4
Comparative height size at age 10 0.1 0.3 2.3 -0.6 0.2 -0.1 -0.8 -0.5 0.4 0.5 0.0 1.5 0.1 0.3 0.1 1.3 0.1 0.5 0.5 0.2 -0.4 0.5 0.5 -0.6 0.2 -0.1 0.5 0.6 -0.1 0.2 0.6 0.4 0.2
Number of full sisters 0.7 0.9 3.5 -1.2 -0.3 -1.0 -1.1 -1.1 -0.9 -0.2 -0.9 -1.4 -0.7 -0.9 -0.9 -1.9 -0.9 -1.0 -1.2 -0.9 -1.0 -1.0 -0.5 0.3 -0.5 -0.6 -1.2 -0.8 -0.3 -1.0 -0.7 -1.1 -0.7
Suffer from ‘nerves’ 8.0 12.6 18.8 -3.8 -3.0 -4.2 -3.9 -4.2 -3.6 -3.2 -4.1 -3.7 -3.3 -3.2 -4.1 -2.8 -3.5 -3.3 -3.6 -3.9 -4.3 -3.7 -2.8 2.4 -3.6 -4.3 -3.1 -3.3 -2.1 -3.9 -3.1 -3.7 -3.7
Overall health rating 7.9 17.0 30.7 -3.6 -3.1 -4.6 -4.9 -4.5 -4.7 -3.4 -3.8 -2.8 -4.3 -5.2 -4.9 -2.0 -3.9 -4.5 -4.0 -4.6 -4.1 -4.2 -4.4 3.6 -4.8 -4.7 -5.5 -3.5 -2.4 -4.5 -3.3 -3.6 -4.3
Chest pain or discomfort 4.9 7.0 11.4 -2.3 -2.6 -2.9 -3.0 -2.9 -3.0 -2.6 -2.7 -1.3 -2.8 -3.1 -3.4 -1.1 -2.5 -2.7 -1.8 -3.3 -2.4 -2.7 -2.6 2.3 -2.9 -3.2 -3.1 -2.5 -1.7 -3.2 -2.3 -2.4 -2.8
Had major operations 0.3 0.3 2.3 -0.2 0.5 -1.1 -0.1 -1.0 -0.3 -1.5 -0.4 0.6 -0.1 -0.1 -0.7 -0.7 -0.4 -0.6 0.5 -0.5 -0.8 -0.5 -0.0 -0.1 -0.2 -0.4 -0.4 -0.1 0.1 -0.5 0.1 -0.3 -0.3
Age at last live birth 3.0 4.4 8.2 1.2 2.2 1.9 2.2 1.0 2.4 2.8 2.1 2.4 2.5 2.5 2.1 1.6 2.5 2.3 2.9 1.8 1.0 1.9 2.4 -2.6 1.9 2.0 1.8 0.3 1.2 2.5 2.2 2.4 2.1
Family relationship satisfaction 0.2 0.3 1.0 0.4 -0.0 0.4 0.9 0.7 0.2 -0.3 0.4 0.8 0.2 -0.1 -0.1 0.6 -0.0 0.5 0.7 0.0 1.0 0.5 0.1 -0.2 -0.3 0.8 -0.1 0.3 -0.1 0.2 0.9 1.0 0.5
Leg pain on walking 0.9 1.1 2.8 -0.9 -0.6 -1.4 -0.7 -1.2 -1.1 -0.7 -0.8 -1.7 -1.1 -1.0 -1.6 -1.3 -1.0 -0.9 -0.7 -1.3 -0.9 -0.7 -0.8 0.6 -1.4 -1.4 -1.2 -0.9 -0.7 -0.8 -0.9 -0.6 -1.2
Qualifications: NVQ or HND or HNC or equivalent 1.5 1.8 4.2 -1.5 -1.3 -1.5 -0.8 -0.7 -1.5 -1.7 -1.2 -1.6 -1.3 -1.2 -1.7 -0.8 -1.6 -0.9 -0.8 -1.8 -0.8 -1.4 -1.2 1.2 -2.0 -1.3 -1.3 -2.1 -1.5 -1.2 -0.8 -0.9 -1.2
Commuting to job workplace: Car/motor vehicle 0.4 0.5 1.2 0.2 0.8 0.7 0.8 0.9 0.4 1.0 0.8 0.4 0.8 0.1 0.8 1.0 -0.1 0.0 -0.3 0.5 1.1 0.9 0.8 -0.8 0.5 0.7 -0.4 1.1 -0.1 0.7 0.9 0.6 0.8
Illness, injury, bereavement, stress in last 2 years 1.9 2.3 5.3 0.7 1.2 1.3 2.3 1.3 1.6 1.5 1.7 0.8 1.8 1.6 1.4 1.2 1.8 1.6 1.4 1.5 1.6 1.5 1.4 -1.4 1.9 1.4 1.6 1.3 1.8 1.8 1.6 1.0 1.5
Medication: Aspirin 1.4 1.8 5.8 -1.6 -0.1 -1.9 -2.3 -2.4 -1.0 -0.9 -1.3 -0.8 -0.5 -1.1 -2.0 -0.6 -1.0 -1.3 -1.6 -1.7 -1.8 -1.4 -0.4 -0.2 -1.1 -2.0 -1.7 -1.4 -0.1 -1.7 -0.4 -0.7 -0.8
Supplements: Vitamin C 0.5 0.5 6.4 -1.0 0.5 -1.0 -0.8 -0.5 0.3 -2.5 -0.2 0.0 0.8 0.6 -0.5 -0.7 -0.2 0.0 0.1 -0.7 -0.2 0.6 1.1 -1.0 0.2 -0.3 0.2 0.8 0.4 -0.2 0.1 0.4 0.1
Knee pain experienced in last month 0.2 0.3 1.4 -0.8 0.0 -1.2 -1.1 -1.1 0.2 -0.8 -0.3 -0.4 0.2 -0.0 -0.3 -0.4 0.5 0.1 -0.7 -0.5 -1.1 -0.4 0.1 -0.4 -0.1 -0.5 -0.2 -0.2 0.4 -0.2 0.2 0.3 -0.1
Hypertension (Self-reported) 0.1 0.4 2.4 1.0 0.9 0.4 -0.7 -0.3 0.6 -1.5 0.2 0.1 0.7 0.5 -0.1 0.8 0.5 1.1 -0.5 -0.5 -0.0 -0.1 0.2 -0.5 -0.7 -0.2 0.4 -0.5 0.3 0.5 0.8 1.2 0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 4.3 5.1 8.8 -1.8 -2.6 -2.5 -1.8 -2.5 -2.5 0.5 -2.0 -1.6 -2.5 -2.7 -2.0 -2.8 -1.6 -3.0 -1.6 -1.7 -2.4 -2.4 -2.7 2.2 -1.9 -2.3 -2.6 -2.1 -1.6 -2.3 -2.2 -2.8 -2.2
Illnesses of father: Heart disease 0.2 0.2 1.6 0.2 -0.1 0.1 -0.0 -0.2 -0.4 -0.2 -0.4 0.1 -0.2 -0.2 -0.6 -1.2 -0.6 -0.6 -0.1 -0.4 0.1 -0.1 -0.7 0.8 -0.3 -0.2 0.4 -0.4 -0.7 -0.4 -1.1 -0.2 -0.6
Illnesses of siblings: Diabetes 2.5 3.0 10.3 -1.8 -1.1 -1.0 -2.3 -1.8 -1.7 0.0 -1.7 -2.6 -1.3 -1.4 -1.6 -0.9 -2.2 -1.9 -3.2 -1.4 -1.7 -1.9 -1.2 0.9 -1.8 -1.5 -1.9 -1.7 -2.1 -1.8 -1.3 -1.8 -1.5
Smoking status: Previous 0.9 1.4 5.7 -1.6 0.3 -0.8 -1.9 -1.7 0.0 -0.8 -1.5 -1.5 0.3 0.4 -0.6 -1.8 -1.0 0.5 -1.1 -1.3 -1.8 -1.4 0.4 -0.9 -1.1 -1.1 0.2 -2.4 -2.2 -0.7 -0.3 -0.0 -0.7
Forced expiratory volume in 1-second (FEV1), predicted 1.4 2.9 4.7 -1.9 -1.9 -2.0 -1.3 -0.9 -1.9 -1.7 -2.0 -1.4 -2.1 -1.6 -2.0 -1.0 -2.0 -1.5 -1.1 -1.4 -1.3 -1.6 -1.9 2.0 -1.6 -1.5 -0.9 -2.2 -2.0 -1.9 -2.1 -2.0 -1.7
Whole body fat-free mass 0.1 0.6 2.2 0.5 1.2 0.4 -0.8 0.4 0.8 -1.5 0.8 0.8 1.1 0.7 0.6 1.0 0.3 1.0 0.0 0.5 0.5 0.8 0.9 -1.0 0.3 0.4 0.5 0.4 -0.4 0.8 0.8 1.5 0.8
Leg fat-free mass (right) 0.1 0.3 2.0 -0.6 0.3 -0.4 -1.4 -0.5 -0.2 -1.2 -0.0 0.1 0.1 -0.2 -0.5 0.4 -0.7 -0.1 -0.6 -0.6 -0.4 -0.0 -0.0 -0.2 -0.7 -0.4 -0.4 -0.3 -1.0 -0.2 -0.0 0.5 -0.2
Arm fat percentage (left) 0.6 2.4 4.0 -1.7 -0.7 -1.7 -1.8 -2.0 -1.6 -2.0 -1.3 -1.4 -1.1 -1.4 -1.7 -1.0 -1.9 -1.8 -1.9 -1.6 -1.9 -1.0 -1.0 0.9 -1.7 -2.0 -1.6 -1.3 -1.6 -1.4 -1.1 -1.4 -1.6
Average weekly red wine intake 0.3 0.5 1.8 0.9 -0.6 0.2 0.4 1.0 -0.6 0.2 -0.2 -1.3 -0.8 -0.6 0.2 0.6 -0.9 -0.5 -0.6 -0.2 0.6 -0.3 -0.9 1.1 -0.5 0.3 -0.6 -0.4 -1.2 -0.4 -1.0 -0.5 -0.2
Handedness (chirality/laterality): Left-handed 0.2 0.2 0.6 0.5 0.3 0.5 0.5 0.3 0.4 0.5 0.7 0.6 0.3 0.1 0.5 0.6 0.6 0.2 0.6 0.5 0.5 0.4 0.1 -0.4 0.6 0.5 0.1 0.3 -0.1 0.4 0.3 0.5 0.4
Mood swings 5.2 9.4 13.8 -2.8 -2.3 -3.6 -3.5 -3.4 -3.1 -2.7 -3.3 -2.7 -3.1 -3.0 -3.7 -2.6 -2.6 -2.5 -3.1 -3.2 -3.6 -3.3 -3.0 2.8 -3.4 -3.1 -2.6 -3.7 -2.1 -3.3 -2.9 -2.9 -3.3
Loneliness, isolation 2.4 3.3 6.4 -1.2 -1.7 -1.7 -1.3 -1.6 -2.2 -2.0 -2.0 -1.2 -2.5 -2.1 -1.9 -0.9 -1.5 -1.5 -0.6 -1.8 -1.8 -1.9 -2.2 2.1 -2.3 -1.9 -1.7 -2.5 -1.2 -1.9 -1.8 -2.0 -2.0
Long-standing illness, disability or infirmity 2.5 3.8 7.5 -2.0 -1.5 -2.7 -2.1 -2.2 -2.2 -2.7 -2.1 -0.1 -1.9 -2.4 -2.6 -0.8 -1.9 -2.0 -1.8 -2.2 -1.7 -1.6 -1.7 1.4 -2.5 -1.9 -2.6 -1.2 -1.0 -2.6 -1.1 -1.3 -1.7
Ever had bowel cancer screening 0.8 1.0 2.5 -0.5 -0.5 -1.6 -0.9 -1.2 -0.9 -1.3 -0.8 -0.6 -1.1 -0.7 -0.8 -1.4 -0.6 -1.0 -1.2 -1.2 -1.2 -1.0 -0.7 0.5 -0.5 -1.3 -0.8 -0.6 -0.3 -1.0 -1.5 -1.2 -1.1
Diabetes diagnosed by doctor 0.6 0.9 3.2 -0.2 -0.8 -0.4 -1.0 -0.5 -1.1 -1.4 -0.9 -0.9 -0.5 -1.1 -1.3 0.1 -1.1 -0.6 -1.8 -1.0 -0.5 -1.1 -1.1 1.0 -1.6 -0.4 -1.2 -0.9 -0.3 -1.1 -0.5 -0.5 -0.8
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.8 2.0 -1.3 -1.2 -0.9 -0.6 -1.3 -0.8 0.3 -0.9 -1.1 -0.8 -0.5 -0.6 1.0 -0.2 -0.7 -0.6 -0.7 -1.4 -1.2 -0.9 0.5 -1.2 -0.6 -0.6 -1.4 -0.4 -0.8 -1.1 -0.6 -0.9
Friendships satisfaction 2.2 2.8 5.3 2.2 1.2 1.7 2.0 2.1 1.4 1.1 1.9 1.7 0.9 1.2 1.7 1.9 1.8 1.7 1.9 1.7 2.1 1.6 0.9 -0.5 1.2 2.3 1.4 1.5 1.9 1.9 1.6 1.8 1.6
Qualifications: nursing, teaching 6.9 10.7 21.7 4.0 1.6 4.5 3.6 4.0 2.7 2.3 3.9 3.7 2.1 2.6 3.4 4.7 3.2 2.9 3.7 3.6 4.2 3.4 2.0 -1.5 2.1 3.8 2.2 2.9 2.8 3.9 3.0 3.5 3.2
Commuting to job workplace: Walk 0.5 0.5 2.1 0.5 -1.2 -0.6 -0.7 -0.2 -0.8 -1.5 -0.4 -0.5 -1.2 -0.8 -0.8 -0.6 -0.3 -0.4 0.3 -0.4 -0.3 -0.2 -1.0 1.2 -0.9 -0.7 -0.5 -0.5 0.0 -0.6 -0.3 -0.5 -0.7
Eye problems/disorders: Cataract 0.6 0.7 1.7 -0.9 -0.7 -0.7 -0.3 -1.0 -0.6 0.7 -1.0 -1.3 -1.0 -0.6 -0.5 -0.9 -0.5 -1.0 -1.2 -0.5 -1.2 -0.9 -0.7 0.8 -0.5 -0.8 -0.6 -0.8 -0.6 -0.8 -0.9 -1.2 -0.9
Mouth/teeth dental problems: Mouth ulcers 0.3 0.4 2.2 1.4 -0.2 -0.0 0.3 0.6 0.4 -0.0 0.4 1.4 0.4 0.3 0.6 -0.3 1.0 0.1 0.7 0.3 0.5 0.2 0.0 0.3 1.2 0.1 0.4 0.7 1.5 0.4 0.1 -0.2 0.4
Medication for cholesterol 0.7 1.1 5.5 0.1 0.2 1.1 0.7 0.9 0.6 2.3 1.1 0.9 0.4 0.4 1.2 1.2 1.3 0.0 1.5 1.2 0.7 1.3 0.9 -1.0 1.5 1.7 -0.1 1.3 1.0 0.7 0.7 0.7 1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.4 2.2 0.8 0.4 0.2 0.5 0.7 0.4 1.1 0.7 1.5 0.4 0.2 0.8 0.4 0.2 0.3 0.6 0.5 1.0 0.6 0.2 -0.1 0.2 0.7 0.3 0.5 -0.4 0.6 0.4 0.5 0.4
Back pain experienced in last month 3.3 4.8 9.3 -2.0 -2.2 -3.0 -2.4 -2.5 -2.2 -2.4 -2.2 -2.3 -2.1 -2.1 -2.5 -2.7 -1.6 -2.1 -1.9 -2.3 -2.4 -2.0 -2.0 1.6 -1.9 -2.6 -2.1 -1.7 -0.3 -2.4 -2.3 -1.9 -2.3
Mineral and other dietary supplements 0.3 0.4 2.0 0.2 -0.8 1.0 1.4 1.1 -0.2 -0.0 0.5 -0.5 -0.4 -0.2 0.4 1.4 0.4 0.3 -0.0 0.8 1.0 -0.0 -0.6 0.8 -0.3 0.7 -0.1 0.2 0.7 0.8 0.7 0.1 0.1
Breast cancer (self-reported) 1.0 1.2 5.8 -1.5 0.5 -0.8 -2.4 -1.8 -0.3 0.7 -1.5 -0.9 -0.1 0.1 -0.4 -1.4 -1.0 -0.3 -1.0 -0.8 -1.9 -1.4 0.0 -0.6 -0.8 -1.0 -0.2 -1.6 -1.8 -1.1 -0.5 -0.8 -0.8
Asthma (self-reported) 0.2 0.4 1.8 0.4 0.2 0.3 0.8 1.2 -0.1 -0.8 1.0 1.4 -0.5 -0.3 0.4 -0.2 0.6 0.2 1.1 0.5 0.9 0.9 -0.2 0.5 0.5 0.9 -0.2 0.3 0.7 0.4 -0.2 0.3 0.4
Osteoporosis (self-reported) 0.1 0.1 1.1 0.6 -0.0 0.0 -0.2 0.1 0.1 -0.3 0.3 -0.0 0.2 -0.0 0.7 1.1 0.1 -0.1 -0.7 0.1 -0.2 0.1 0.2 -0.0 0.7 0.1 -0.1 0.2 -0.1 -0.1 -0.2 -0.6 0.3
Osteoarthritis (self-reported) 0.4 0.5 1.5 -1.2 -0.1 -0.7 -0.3 -1.1 -0.6 -0.4 -0.6 -0.7 -0.4 -0.7 -0.6 -0.1 -0.6 -0.7 -0.9 -0.6 -0.9 -0.7 -0.7 0.4 -1.1 -1.0 -0.8 -0.9 -0.7 -0.6 -0.2 -0.3 -0.6
Medication: Aspirin 1.7 2.2 6.1 -1.7 -0.2 -1.8 -2.4 -2.5 -1.3 -0.7 -1.4 -1.3 -0.9 -1.6 -1.9 -0.5 -1.1 -1.7 -1.8 -1.7 -1.9 -1.7 -0.8 0.2 -1.3 -2.1 -2.2 -1.4 -0.3 -1.8 -0.5 -1.0 -1.0
Medication: Gliclazide 2.0 2.3 4.9 -1.4 -1.2 -1.6 -1.7 -1.5 -1.8 -1.8 -1.4 -1.2 -1.1 -2.0 -2.2 -0.6 -1.5 -1.6 -1.2 -1.8 -1.5 -1.5 -1.4 1.3 -1.4 -1.6 -2.0 -1.2 -0.6 -1.7 -1.3 -1.5 -1.6
Illnesses of father: None of the above (group 1) 0.1 0.1 0.5 -0.7 -0.4 -0.4 0.1 0.0 0.3 -0.1 0.4 -0.7 0.1 0.1 0.5 0.3 -0.1 0.2 -0.1 0.1 -0.2 -0.2 0.3 -0.4 0.3 -0.0 -0.1 0.5 -0.1 0.3 0.5 -0.1 0.2
Smoking status: Current 1.4 2.3 5.5 -0.6 -1.0 -1.7 -1.2 -1.1 -2.0 -1.2 -1.3 -1.0 -2.2 -2.2 -1.7 0.3 -1.4 -2.2 -1.6 -1.3 -1.2 -1.3 -1.6 1.6 -1.1 -1.2 -2.4 -0.6 -0.4 -1.9 -1.6 -2.1 -1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 2.0 0.5 0.4 1.4 0.7 0.4 1.1 0.7 0.9 0.6 0.8 1.2 0.7 -0.5 0.9 0.9 0.8 0.3 0.7 1.0 0.9 -1.1 0.6 0.7 1.2 0.1 0.5 0.9 0.4 1.3 0.8
Whole body water mass 0.1 0.6 2.3 0.4 1.1 0.3 -0.9 0.3 0.8 -1.5 0.7 0.6 1.0 0.7 0.5 1.1 0.3 1.0 -0.1 0.4 0.4 0.7 0.9 -1.0 0.2 0.3 0.5 0.2 -0.5 0.8 0.8 1.4 0.7
Leg predicted mass (right) 0.1 0.3 2.0 -0.6 0.3 -0.4 -1.4 -0.6 -0.2 -1.3 -0.1 0.1 0.1 -0.2 -0.5 0.3 -0.7 -0.1 -0.7 -0.6 -0.4 -0.1 -0.0 -0.2 -0.7 -0.4 -0.4 -0.3 -1.0 -0.2 -0.1 0.5 -0.2
Arm fat mass (left) 0.3 1.3 4.6 -1.1 -0.1 -1.5 -1.7 -1.6 -1.0 -2.1 -0.8 -1.1 -0.4 -0.8 -1.2 -0.8 -1.3 -1.2 -1.6 -1.2 -1.6 -0.6 -0.4 0.3 -1.1 -1.6 -1.2 -0.9 -1.2 -0.9 -0.6 -0.7 -1.0
Number of self-reported non-cancer illnesses 2.3 4.0 7.7 -1.3 -0.9 -2.6 -2.2 -2.5 -1.8 -2.6 -1.9 -1.0 -1.4 -1.8 -2.3 -1.0 -2.1 -1.4 -2.4 -2.6 -2.4 -2.4 -1.6 0.8 -2.6 -2.7 -2.2 -2.8 -2.2 -1.9 -1.4 -1.2 -1.9
Average weekly champagne plus white wine intake 2.6 3.6 7.0 2.2 0.8 2.1 1.4 2.3 2.2 0.8 2.1 0.9 1.9 1.7 1.9 1.2 2.1 2.2 1.3 1.5 2.6 1.8 1.9 -1.8 2.2 2.3 1.4 1.8 2.1 2.0 2.3 2.0 2.3
Miserableness 11.7 20.3 28.6 -3.9 -3.6 -5.2 -4.7 -5.1 -4.2 -4.5 -4.9 -4.7 -4.3 -3.9 -5.1 -4.6 -4.2 -3.6 -4.6 -4.7 -5.3 -4.9 -4.0 3.3 -4.8 -5.2 -3.5 -5.4 -4.0 -4.5 -4.4 -4.3 -5.0
Guilty feelings 3.3 4.9 9.5 -2.7 -0.8 -2.6 -2.1 -3.0 -1.9 -2.2 -2.3 -2.9 -1.3 -1.6 -2.5 -2.3 -1.9 -2.0 -2.3 -2.4 -3.1 -2.4 -1.4 1.0 -2.0 -2.5 -1.8 -2.6 -2.1 -2.5 -2.2 -2.0 -2.0
Wears glasses or contact lenses 0.6 0.7 2.4 1.1 0.5 0.3 1.6 1.3 0.8 -1.2 0.9 0.7 0.9 0.8 0.4 0.1 0.3 1.1 0.5 0.7 1.2 0.8 0.5 -0.1 0.3 0.6 1.3 0.7 0.3 1.2 0.4 1.0 0.5
Ever taken oral contraceptive pill 0.9 1.1 2.7 -0.4 0.8 1.3 1.7 1.2 0.9 1.1 0.8 0.4 0.7 1.3 1.2 -0.1 1.0 1.0 1.6 1.6 0.9 1.0 0.9 -0.5 0.5 1.2 1.4 0.2 0.3 1.4 1.0 0.8 0.8
Hearing aid user 0.2 0.3 1.3 -0.3 0.6 -0.0 0.1 -0.4 0.4 -1.1 0.2 0.7 0.7 0.3 0.1 -0.3 0.6 0.2 0.2 0.4 -0.0 0.4 0.5 -0.4 0.5 -0.3 0.2 0.8 1.1 -0.3 0.6 0.4 0.5
Mother’s age at death 4.9 6.2 9.7 2.2 2.8 3.1 2.2 2.6 2.6 2.3 2.6 1.3 3.0 2.8 3.0 2.1 2.2 2.5 1.2 2.8 2.5 2.5 2.6 -2.2 2.2 2.4 2.4 2.3 1.6 3.0 2.9 2.5 2.7
Financial situation satisfaction 1.4 1.8 3.2 -1.0 -0.9 -1.5 -1.7 -1.7 -1.4 -1.1 -0.9 -1.0 -1.8 -1.7 -1.4 -1.2 -0.5 -1.3 -0.8 -1.4 -1.5 -1.3 -1.8 1.5 -1.5 -1.6 -1.5 -1.4 -0.7 -1.3 -1.1 -1.1 -1.4
Tinnitus: Yes, now most or all of the time 0.3 0.4 1.4 -0.4 -1.2 -0.5 -0.7 -0.9 -0.6 -0.5 -0.7 -0.1 -0.3 -0.8 -0.5 -0.1 -0.4 -0.7 0.5 -0.7 -0.7 -0.7 -0.8 0.8 -0.5 -1.0 -0.6 -0.2 0.4 -0.7 -0.4 -0.6 -0.6
Commuting to job workplace: Public transport 1.3 1.5 3.3 1.4 1.2 0.9 0.5 0.9 1.6 0.9 1.0 1.8 1.5 1.5 0.9 0.6 1.5 1.8 1.6 0.9 0.7 0.7 1.3 -1.1 1.0 1.6 1.5 0.4 1.0 1.0 1.3 1.7 1.4
Eye problems/disorders: Glaucoma 0.4 0.4 2.5 0.2 0.6 0.4 0.8 0.4 0.7 -0.2 0.6 1.6 0.6 0.5 0.9 -0.1 0.5 0.5 1.0 0.9 0.0 0.4 0.6 -0.3 0.6 0.8 0.4 1.0 0.5 0.7 0.3 0.4 0.6
Medication: Blood pressure 0.2 0.3 1.7 0.7 -0.2 -0.3 -0.1 -0.3 -0.3 -1.3 -0.4 -1.2 -0.2 -0.2 -0.6 -0.3 -0.4 0.3 -1.0 -0.1 -0.2 -0.2 -0.7 0.7 -0.9 -1.1 0.4 -0.5 -0.1 0.2 0.1 -0.2 -0.8
Pain type(s) experienced in last month: Hip pain 0.7 0.9 2.4 -0.3 0.2 0.9 0.0 0.2 0.8 1.5 0.7 1.4 0.8 0.8 1.2 1.3 1.4 0.5 0.2 1.6 0.2 0.7 0.9 -1.0 1.0 0.7 0.4 1.3 1.3 0.7 0.9 0.7 1.0
Supplements: Fish oil (including cod liver oil) 0.5 0.6 2.5 -1.2 1.0 -0.7 -1.6 -1.4 0.5 0.2 -0.7 0.3 0.8 0.4 -0.5 -1.2 -0.4 0.2 -0.3 -0.5 -1.3 -0.3 0.8 -1.0 0.2 -1.0 0.5 -0.8 -1.0 -0.7 -0.1 0.1 -0.1
High cholesterol (Self-reported) 0.3 0.5 3.1 -0.0 0.1 -0.7 -0.8 -1.0 0.0 -1.8 -0.6 0.4 -0.0 0.2 -0.6 -0.8 0.0 0.5 -0.4 -0.6 -0.7 -0.7 -0.2 -0.1 -1.1 -1.1 0.4 -1.6 -0.3 -0.2 0.2 0.4 -0.4
Medication: Bendroflumethiazide 0.2 0.3 1.3 0.5 0.6 0.5 0.5 0.5 0.5 0.1 0.2 0.2 0.5 0.8 0.3 0.7 0.3 1.1 -0.0 0.4 0.5 0.6 0.4 -0.2 -0.3 0.2 1.1 -0.2 -0.1 0.6 1.1 0.8 0.4
Medication: Paracetamol 1.3 2.1 4.7 -2.1 -1.4 -1.2 -1.6 -1.3 -1.4 -1.4 -1.6 -0.6 -1.2 -1.1 -1.5 -0.9 -1.7 -1.0 -0.6 -1.4 -1.5 -1.6 -1.3 1.4 -2.0 -1.2 -0.8 -2.0 -2.2 -1.3 -1.2 -1.3 -1.6
Medication: Lisinopril 0.7 0.9 2.5 -0.4 0.3 -0.8 -1.1 -1.4 -0.6 -1.3 -0.6 -1.6 -0.7 -0.7 -1.1 -1.3 -0.1 -0.2 -1.1 -1.1 -1.4 -1.1 -0.8 0.5 -1.0 -1.4 -0.5 -1.2 0.1 -0.5 -1.0 -0.4 -1.0
Medication: Atorvastatin 1.9 2.3 5.0 -0.8 -0.2 -1.8 -1.2 -1.9 -1.6 -1.9 -1.6 -1.2 -1.0 -1.5 -2.1 -2.2 -1.6 -1.7 -1.5 -2.1 -1.3 -1.6 -0.9 0.5 -1.6 -1.8 -2.2 -1.4 -0.8 -1.7 -0.8 -1.2 -1.5
Illnesses of father: High blood pressure 0.7 0.9 2.0 0.9 1.0 1.0 1.3 1.1 0.9 0.4 0.8 0.7 0.9 1.0 0.7 1.4 0.8 0.9 0.8 0.8 1.3 1.1 0.7 -0.5 0.7 1.2 1.2 0.8 0.8 1.1 0.7 1.1 0.9
Alcohol drinker status: Never 2.3 2.7 6.5 -0.7 -2.5 -0.8 -1.1 -1.6 -1.9 -0.8 -1.3 -1.7 -2.6 -2.0 -1.3 -0.8 -0.8 -1.8 -1.8 -0.8 -1.7 -1.7 -2.5 2.2 -1.9 -1.4 -1.6 -1.6 -1.1 -1.4 -1.4 -1.9 -1.9
Ever smoked 1.0 1.8 4.6 -1.3 0.2 -1.6 -1.9 -1.6 -0.9 -2.1 -1.6 -1.2 -0.9 -0.7 -0.9 -1.7 -1.6 -0.7 -1.0 -1.2 -1.8 -1.6 -0.6 0.4 -1.4 -1.4 -0.7 -1.9 -2.1 -1.3 -1.2 -1.1 -1.1
Basal metabolic rate 0.1 0.4 2.3 0.2 0.9 0.2 -0.9 0.1 0.5 -1.5 0.6 0.5 0.8 0.5 0.3 0.9 0.1 0.7 -0.2 0.3 0.2 0.6 0.7 -0.7 0.0 0.1 0.3 0.2 -0.5 0.6 0.6 1.1 0.5
Leg fat percentage (left) 0.1 0.4 1.5 -0.4 -0.1 -0.8 -0.7 -1.1 -0.7 -1.0 -0.3 -0.5 -0.3 -0.4 -0.1 0.1 -0.4 -1.0 -0.9 -0.1 -1.2 0.0 -0.3 0.5 -0.2 -1.1 -0.5 -0.1 -0.3 -0.3 -0.3 -0.8 -0.6
Arm fat-free mass (left) 0.2 1.0 2.7 0.9 1.4 0.5 -0.7 0.4 1.1 -1.2 1.1 0.6 1.5 1.0 0.9 1.4 0.7 1.2 0.1 0.6 0.5 1.1 1.4 -1.5 0.7 0.4 0.5 0.5 0.1 1.1 1.3 1.6 1.1
Number of operations (self-reported) 2.1 3.2 6.5 -0.7 -1.6 -1.9 -2.1 -2.1 -2.2 -1.1 -1.6 -1.0 -2.2 -2.4 -2.2 -1.1 -1.7 -2.5 -0.7 -1.7 -2.1 -1.6 -1.8 1.6 -1.8 -2.2 -2.6 -0.7 -0.5 -2.2 -1.2 -1.7 -1.9
Average weekly beer plus cider intake 0.4 0.6 4.2 -2.1 0.3 -0.7 -1.3 -0.8 -0.4 -1.0 -0.5 -0.3 -0.1 -0.6 -0.7 -0.1 -0.7 -0.3 -1.3 -0.5 -0.6 -0.5 -0.2 -0.1 -0.7 -0.7 -0.6 -1.0 -1.6 -0.6 -0.2 -0.2 -0.4
Irritability 0.5 0.9 6.1 -0.3 -0.2 -1.7 -1.0 -0.9 -0.2 -2.5 -1.0 -0.9 -0.1 -0.0 -1.2 0.4 -0.7 0.3 -0.8 -1.7 -1.1 -1.2 -0.3 0.2 -0.6 -1.0 0.3 -1.2 -0.4 -0.9 -0.7 -0.4 -0.6
Risk taking 5.0 7.3 11.8 2.4 2.3 2.7 2.4 3.1 2.8 0.3 3.1 1.8 2.9 2.8 2.7 2.9 2.3 2.7 2.7 2.7 3.4 2.9 2.7 -2.5 2.7 3.4 2.3 2.7 2.0 3.1 2.6 3.2 3.1
Ever had prostate specific antigen (PSA) test 1.5 1.7 3.8 -1.9 -1.3 -1.4 -1.0 -1.1 -1.4 -0.3 -1.5 -0.9 -1.2 -1.1 -1.3 -0.7 -1.5 -1.3 -1.6 -1.1 -1.2 -1.5 -1.5 1.3 -1.4 -1.4 -0.7 -0.8 -1.4 -1.5 -1.8 -1.4 -1.7
Fractured/broken bones in last 5 years 1.2 1.6 4.6 -0.5 -1.2 -1.0 -0.5 -0.6 -1.3 -1.7 -1.4 -0.8 -1.2 -1.1 -0.9 0.7 -1.7 -1.4 -1.8 -1.2 -1.2 -1.6 -1.3 1.5 -0.6 -1.1 -0.8 -0.1 -0.8 -1.3 -2.1 -2.1 -1.5
Age started oral contraceptive pill 2.8 3.6 6.3 2.0 2.5 2.5 1.9 2.1 1.9 1.3 1.9 1.6 1.8 2.0 1.9 1.4 1.5 1.8 1.3 1.3 2.1 2.0 2.1 -1.9 2.0 1.9 1.8 2.4 1.8 1.7 1.7 1.7 2.1
Diastolic blood pressure, automated reading 1.9 5.8 8.6 -2.1 -1.1 -2.9 -2.6 -2.5 -2.3 -1.7 -2.8 -2.5 -2.1 -2.2 -2.7 -1.9 -2.6 -2.4 -2.9 -2.7 -2.6 -2.7 -2.1 2.1 -2.6 -2.5 -1.8 -2.3 -2.1 -2.6 -2.8 -2.5 -2.9
Ever depressed for a whole week 4.9 6.1 12.4 -2.5 -2.6 -1.9 -2.0 -2.0 -3.1 -1.1 -2.6 -1.2 -3.1 -2.9 -2.6 -0.4 -2.8 -2.6 -0.5 -2.0 -2.3 -2.7 -3.2 3.5 -3.2 -2.5 -2.0 -1.9 -2.1 -2.5 -3.0 -2.8 -3.1
Unable to work because of sickness or disability 6.6 8.5 16.6 -3.2 -2.2 -4.1 -3.1 -2.9 -3.3 -2.3 -2.9 -1.6 -3.3 -3.3 -3.1 -2.1 -2.7 -3.2 -2.4 -3.2 -2.8 -2.9 -3.0 2.9 -3.2 -3.0 -3.2 -2.7 -2.1 -3.2 -2.7 -3.0 -3.0
Commuting to job workplace: Cycle 1.9 2.3 6.2 1.1 1.4 2.0 1.7 1.2 1.9 0.5 1.3 0.6 1.6 2.3 1.8 0.5 1.5 1.9 1.1 1.9 0.8 1.4 1.7 -1.5 1.5 1.7 2.5 0.8 0.6 1.8 1.1 1.5 1.4
Myopia 3.3 4.8 10.9 0.8 1.9 1.3 1.9 1.9 2.9 0.3 2.0 2.9 2.8 3.2 2.2 1.3 1.5 2.7 1.6 2.1 2.0 2.1 2.7 -2.4 2.7 2.1 3.3 2.6 1.1 2.1 1.7 1.9 2.2
Vascular/heart problems diagnosed by doctor 0.3 0.8 3.3 0.3 -0.0 0.5 1.6 1.2 0.5 1.6 0.7 0.3 0.1 0.5 1.3 -0.5 0.7 0.0 1.3 1.4 0.8 0.9 0.5 -0.1 1.8 1.0 0.7 1.2 0.7 0.7 -0.3 -0.4 0.8
Cholesterol lowering medication 1.1 1.6 6.0 -1.0 -0.3 -1.0 -2.4 -1.6 -1.0 -1.5 -1.3 -1.4 -0.5 -0.9 -1.9 -0.4 -1.4 -0.6 -2.1 -1.6 -1.3 -1.2 -0.9 0.5 -1.9 -1.8 -0.9 -1.5 -0.7 -1.1 -0.5 -0.3 -1.2
Medication: Omeprazole (e.g. Zanprol) 3.4 4.1 8.4 -2.6 -1.5 -2.3 -2.6 -2.9 -1.9 0.1 -1.9 -1.3 -1.8 -1.9 -2.1 -2.2 -1.6 -1.8 -2.2 -1.8 -2.7 -2.2 -2.0 1.4 -2.4 -2.8 -1.7 -2.5 -1.7 -1.4 -1.6 -1.7 -2.4
Pain experienced in last month 1.9 3.2 9.5 1.8 1.4 3.1 2.0 2.5 1.5 1.4 1.9 1.6 1.7 1.5 1.9 2.6 0.9 1.5 2.1 2.0 2.4 1.7 1.4 -0.9 1.3 2.0 1.5 1.4 0.2 2.0 1.9 1.4 1.9
Supplements: Calcium 1.5 1.7 5.3 0.9 2.2 0.3 0.3 0.3 1.7 -1.1 1.5 0.7 1.9 1.5 1.2 -0.7 1.2 1.0 0.6 1.1 0.6 1.3 2.1 -2.3 1.7 0.7 0.8 1.6 1.0 1.0 1.2 1.5 1.4
Basal cell carcinoma (self-reported) 0.5 0.6 3.7 1.2 -0.0 0.1 0.5 -0.4 -0.4 -0.4 0.7 1.4 -0.2 -0.8 -0.0 -0.4 0.9 -1.1 1.4 0.6 0.1 0.7 -0.2 0.1 0.5 -0.0 -1.2 1.3 1.9 0.0 0.1 -0.2 0.3
Heart attack/myocardial infarction (self-reported) 0.9 1.2 3.1 -1.6 -0.1 -1.3 -1.5 -1.8 -0.7 -0.0 -1.1 -0.7 -0.3 -0.7 -1.4 -0.8 -1.2 -0.7 -1.1 -1.4 -1.5 -1.1 -0.2 -0.1 -1.2 -1.5 -0.9 -1.5 -1.3 -1.2 -0.2 -0.4 -0.8
Deep venous thrombosis (DVT) (self-reported) 1.5 1.9 3.7 -1.8 -1.3 -1.7 -1.7 -1.3 -1.2 -0.9 -1.4 -1.8 -1.1 -1.2 -1.8 -1.5 -1.6 -1.3 -1.7 -1.9 -1.5 -0.8 -0.9 0.6 -1.2 -1.9 -1.1 -0.7 -0.7 -1.5 -1.1 -1.1 -1.4
Heart disease (siblings) 4.2 5.1 10.0 -1.4 -1.3 -2.6 -2.0 -3.2 -2.6 -0.3 -2.2 -1.2 -2.2 -2.6 -2.4 -2.4 -1.5 -3.1 -2.3 -2.3 -2.4 -2.3 -2.6 2.2 -1.9 -2.5 -2.5 -1.8 -1.1 -2.7 -2.8 -2.6 -2.3
Alcohol drinker status: Previous 0.1 0.1 0.7 -0.1 0.2 -0.1 -0.8 -0.3 0.3 0.8 -0.3 0.0 0.6 0.5 0.0 -0.0 0.1 0.2 -0.8 -0.3 -0.1 -0.1 0.2 -0.5 0.2 0.0 0.3 -0.5 0.1 -0.1 0.2 -0.1 0.2
Pack years of smoking 0.3 0.4 1.4 0.8 0.2 -0.6 -0.1 0.0 -0.8 -0.6 0.3 0.6 -1.0 -0.9 -0.3 0.5 0.3 -1.0 -0.0 -0.2 0.2 -0.0 -0.8 1.1 -0.3 0.5 -1.1 1.1 1.2 -0.6 -0.2 -0.4 -0.3
Impedance of whole body 0.1 0.5 3.1 -0.7 -1.3 0.0 1.1 0.5 -0.5 1.8 -0.0 0.4 -1.0 -0.7 0.1 -0.5 0.3 -0.6 1.0 0.8 0.4 0.3 -0.9 1.2 0.0 0.1 -0.2 0.4 0.6 -0.3 0.1 -1.1 -0.1
Leg fat mass (left) 0.1 0.3 1.5 -0.5 0.2 -0.7 -1.0 -0.9 -0.4 -1.2 -0.2 -0.3 0.0 -0.3 -0.2 0.4 -0.5 -0.6 -0.8 -0.3 -1.0 0.1 -0.0 0.0 -0.4 -0.9 -0.5 -0.1 -0.5 -0.2 0.0 -0.3 -0.4
Arm predicted mass (left) 0.2 1.1 3.1 0.9 1.3 0.6 -0.6 0.6 1.1 -1.2 1.1 0.9 1.3 1.0 1.0 1.5 0.8 1.4 0.2 0.8 0.6 1.2 1.3 -1.3 0.7 0.6 0.8 0.4 0.1 1.2 1.3 1.7 1.1