Best TWAS P=5.02e-08 · Best GWAS P=9.14e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | RP11-165J3.6 | 0.23 | 0.22 | enet | 10 | 0.22 | 2.3e-12 | 5.3 | 5.2 | 2.1e-07 | 0.98 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Tibial | RP11-165J3.6 | 0.22 | 0.20 | lasso | 2 | 0.19 | 4.9e-15 | 5.3 | 5.2 | 1.5e-07 | 0.98 | 0.00 | 0.99 | FALSE |
| 3 | GTEx | Brain Cerebellum | RP11-165J3.6 | 0.44 | 0.31 | lasso | 7 | 0.28 | 5.0e-09 | 5.3 | 5.2 | 2.5e-07 | 0.98 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Breast Mammary Tissue (Female) | RP11-165J3.6 | 0.21 | 0.02 | lasso | 3 | 0.00 | 2.3e-01 | 5.3 | 5.3 | 1.3e-07 | 0.99 | 0.01 | 0.83 | FALSE |
| 5 | GTEx | Esophagus Gastroesophageal Junction | RP11-165J3.6 | 0.34 | 0.26 | lasso | 8 | 0.27 | 3.0e-10 | 5.3 | 5.3 | 1.2e-07 | 0.98 | 0.00 | 1.00 | FALSE |
| 6 | GTEx | Lung | RP11-165J3.6 | 0.25 | 0.16 | lasso | 7 | 0.17 | 4.1e-13 | 5.3 | 5.5 | 5.0e-08 | 0.97 | 0.01 | 0.99 | TRUE |
| 7 | GTEx | Skin Sun Exposed Lower leg | RP11-165J3.6 | 0.32 | 0.27 | lasso | 5 | 0.35 | 6.8e-30 | 5.3 | 5.1 | 2.7e-07 | 0.96 | 0.01 | 0.99 | FALSE |
| 8 | GTEx | Thyroid | RP11-165J3.6 | 0.35 | 0.27 | lasso | 3 | 0.29 | 1.2e-22 | 5.3 | 5.3 | 9.1e-08 | 0.98 | 0.01 | 0.99 | FALSE |