Best TWAS P=9.06e-08 · Best GWAS P=7e-09 conditioned to 0.0254
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | SLC25A17 | 0.09 | 0.03 | enet | 10 | 0.06 | 4.2e-05 | 5.5 | 5.3 | 9.1e-08 | 0.91 | 0.02 | 0.98 | TRUE |
2 | GTEx | Esophagus Mucosa | RANGAP1 | 0.07 | 0.02 | lasso | 4 | 0.02 | 8.6e-03 | 5.3 | -5.2 | 1.7e-07 | -0.89 | 0.03 | 0.90 | FALSE |