Best TWAS P=7.36e-10 · Best GWAS P=8.92e-09 conditioned to NaN
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ANKK1 | 0.04 | 0.02 | blup | 66 | 0.03 | 5.0e-04 | 4.5 | 6.2 | 7.4e-10 | -0.21 | 0.11 | 0.60 | TRUE |
| 6 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | TTC12 | 0.07 | 0.06 | blup | 48 | 0.04 | 1.6e-02 | 4.6 | 5.8 | 7.0e-09 | -0.19 | 0.02 | 0.66 | TRUE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | DRD2 | 0.06 | 0.07 | lasso | 2 | 0.07 | 6.6e-09 | -5.2 | 5.2 | 2.0e-07 | -0.53 | 0.05 | 0.94 | TRUE |
| 3 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ANKK1 | 0.08 | 0.02 | blup | 66 | 0.04 | 5.6e-03 | 4.4 | -5.1 | 3.0e-07 | 0.17 | 0.07 | 0.61 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ANKK1 | 0.04 | 0.03 | blup | 67 | 0.04 | 6.3e-05 | 4.6 | -5.2 | 2.5e-07 | 0.23 | 0.33 | 0.49 | FALSE |
| 5 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | TTC12 | 0.36 | 0.30 | lasso | 3 | 0.29 | 6.0e-12 | 5.1 | 5.1 | 2.8e-07 | -0.12 | 0.05 | 0.94 | FALSE |