Best TWAS P=1.22e-07 · Best GWAS P=6.97e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | MMAB | 0.12 | 0.09 | enet | 13 | 0.08 | 2.9e-10 | 5.4 | -5.3 | 1.2e-07 | -0.96 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Adipose Visceral Omentum | MMAB | 0.10 | -0.01 | lasso | 4 | 0.00 | 3.8e-01 | -4.8 | -5.3 | 1.4e-07 | -0.82 | 0.04 | 0.67 | FALSE |
| 3 | GTEx | Colon Transverse | KCTD10 | 0.22 | 0.12 | lasso | 11 | 0.13 | 1.1e-06 | -4.7 | -5.2 | 2.6e-07 | -0.90 | 0.05 | 0.94 | FALSE |
| 4 | GTEx | Colon Transverse | MMAB | 0.08 | 0.07 | lasso | 2 | 0.05 | 1.7e-03 | 5.2 | -5.2 | 1.9e-07 | -0.97 | 0.02 | 0.93 | FALSE |
| 5 | GTEx | Whole Blood | MVK | 0.05 | 0.00 | enet | 13 | 0.00 | 4.8e-01 | -4.7 | -5.2 | 2.5e-07 | -0.68 | 0.06 | 0.53 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | MYO1H | 0.05 | 0.02 | blup | 87 | 0.04 | 2.1e-03 | -3.3 | 5.1 | 2.9e-07 | 0.73 | 0.04 | 0.62 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | KCTD10 | 0.15 | 0.08 | lasso | 6 | 0.08 | 2.1e-08 | 4.5 | -5.2 | 2.0e-07 | -0.74 | 0.08 | 0.91 | FALSE |