TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Sensitivity / hurt feelings
:
←
→
chr15:90,718,541-92,120,170
Best TWAS P=3.77e-08 · Best GWAS P=3.2e-08 conditioned to 1
90.8M
91M
91.2M
91.4M
91.6M
91.8M
92M
92.2M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
FURIN
0.12
0.14
lasso
2
0.13
1.2e-15
5.5
-5.5
3.8e-08
-1.00
0.00
1.00
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
FES
0.06
0.05
blup
46
0.07
7.4e-14
-3.9
5.3
1.4e-07
0.77
0.15
0.83
FALSE