TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Nervous feelings
:
←
→
chr17:4,488,884-6,031,861
Best TWAS P=4.21e-08 · Best GWAS P=4.38e-08 conditioned to 1
4.4M
4.6M
4.8M
5M
5.2M
5.4M
5.6M
5.8M
6M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
RPAIN
0.06
0.06
lasso
3
0.06
3.1e-08
-5.4
5.5
4.2e-08
-0.99
0.00
1.00
TRUE
1
GTEx
Esophagus Muscularis
RABEP1
0.13
0.09
lasso
10
0.10
2.1e-06
-5.4
5.1
2.7e-07
-0.95
0.02
0.98
FALSE