Best TWAS P=5.02e-10 · Best GWAS P=5.53e-07 conditioned to 0.00553
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Not Sun Exposed Suprapubic | SRR | 0.18 | 0.16 | enet | 18 | 0.19 | 7.9e-11 | -3.6 | 6.2 | 5.0e-10 | 0.40 | 0.31 | 0.28 | TRUE |
2 | NTR | Blood | TSR1 | 0.04 | 0.00 | bslmm | 420 | 0.01 | 3.1e-04 | -2.1 | 5.8 | 5.3e-09 | 0.20 | 0.03 | 0.04 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SMG6 | 0.04 | 0.01 | blup | 144 | 0.02 | 5.5e-03 | -2.5 | -5.2 | 2.4e-07 | -0.73 | 0.02 | 0.70 | FALSE |