Hub : Genes

RABEP1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0930 0.0310 2.8e-05 0.007 0.035 0.041 0.027 0.036 4.5e-02 3.9e-05 8.5e-06 3.0e-04 3.1e-05
2 GTEx Adrenal Gland 0.1263 0.0586 8.1e-03 0.025 NA 0.003 NA 0.018 4.2e-02 NA 2.4e-01 NA 7.2e-02
3 GTEx Artery Aorta 0.1100 0.0520 9.3e-03 0.069 NA 0.046 NA 0.040 1.2e-04 NA 1.5e-03 NA 2.9e-03
4 GTEx Brain Cerebellum 0.2080 0.0900 6.4e-03 0.161 NA 0.111 NA 0.079 1.7e-05 NA 3.7e-04 NA 2.5e-03
5 GTEx Colon Sigmoid 0.1620 0.0730 7.9e-03 -0.007 NA 0.010 NA -0.008 6.5e-01 NA 1.3e-01 NA 7.7e-01
6 GTEx Colon Transverse 0.1250 0.0450 4.2e-04 0.111 NA 0.077 NA 0.083 5.8e-06 NA 1.5e-04 NA 8.7e-05
7 GTEx Esophagus Gastroesophageal Junction 0.1930 0.0750 1.0e-03 -0.008 NA -0.008 NA -0.003 9.5e-01 NA 8.5e-01 NA 4.2e-01
8 GTEx Esophagus Muscularis 0.1270 0.0430 3.5e-05 0.085 NA 0.083 NA 0.096 7.3e-06 NA 9.2e-06 NA 2.1e-06
9 GTEx Heart Atrial Appendage 0.1280 0.0510 1.6e-03 0.095 NA 0.116 NA 0.094 4.8e-05 NA 7.2e-06 NA 5.1e-05
10 GTEx Liver 0.3000 0.1120 4.5e-03 0.015 NA 0.014 NA 0.046 1.2e-01 NA 1.3e-01 NA 2.0e-02
11 GTEx Lung 0.1077 0.0409 4.6e-04 0.117 NA 0.096 NA 0.102 3.2e-09 NA 8.2e-08 NA 3.4e-08
12 GTEx Muscle Skeletal 0.0639 0.0265 2.9e-03 0.049 NA 0.032 NA 0.039 1.4e-05 NA 4.0e-04 NA 1.0e-04
13 GTEx Nerve Tibial 0.1484 0.0411 8.7e-07 0.151 NA 0.136 NA 0.138 7.9e-11 NA 7.7e-10 NA 5.9e-10
14 GTEx Ovary 0.2830 0.0850 4.3e-04 0.301 NA 0.144 NA 0.259 3.9e-08 NA 2.2e-04 NA 4.6e-07
15 GTEx Pituitary 0.6820 0.0960 2.5e-10 0.497 NA 0.498 NA 0.499 2.2e-14 NA 2.1e-14 NA 1.8e-14
16 GTEx Small Intestine Terminal Ileum 0.2990 0.0910 1.5e-04 0.270 NA 0.195 NA 0.172 9.0e-07 NA 3.9e-05 NA 1.1e-04
17 GTEx Spleen 0.2620 0.0860 6.9e-04 0.263 NA 0.238 NA 0.244 2.0e-07 NA 8.5e-07 NA 6.1e-07
18 GTEx Stomach 0.2640 0.1000 4.7e-04 0.032 NA 0.026 NA 0.061 1.2e-02 NA 2.1e-02 NA 7.3e-04
19 GTEx Testis 0.6940 0.0520 0.0e+00 0.602 NA 0.664 NA 0.679 7.4e-33 NA 1.6e-38 NA 4.9e-40
20 GTEx Thyroid 0.2060 0.0430 2.9e-14 0.269 NA 0.227 NA 0.256 1.2e-20 NA 2.3e-17 NA 1.4e-19
21 GTEx Vagina 0.2910 0.1050 1.0e-03 0.115 NA 0.023 NA 0.062 1.4e-03 NA 9.8e-02 NA 1.6e-02
22 METSIM Adipose 0.1223 0.0310 2.4e-09 0.047 0.068 0.069 0.071 0.078 1.4e-07 1.8e-10 1.4e-10 8.6e-11 9.9e-12
23 ROSMAP Brain Pre-frontal Cortex 0.2021 0.0388 0.0e+00 0.216 0.180 0.196 0.198 0.197 2.6e-27 1.3e-22 1.4e-24 7.4e-25 8.5e-25
24 YFS Blood 0.4553 0.0377 0.0e+00 0.599 0.591 0.619 0.626 0.625 2.2e-252 1.3e-247 4.6e-267 5.5e-272 2.8e-271
25 TCGA Glioblastoma Multiforme 0.2320 0.1100 7.8e-05 0.134 0.146 0.132 NA 0.120 7.1e-05 3.4e-05 8.5e-05 NA 1.8e-04
26 TCGA Brain Lower Grade Glioma 0.0491 0.0236 8.2e-04 0.008 0.018 0.010 NA 0.011 3.8e-02 3.5e-03 2.3e-02 NA 1.7e-02
27 TCGA Pheochromocytoma and Paraganglioma 0.0650 0.0390 8.0e-03 0.001 0.004 -0.007 NA -0.005 2.9e-01 2.1e-01 8.4e-01 NA 5.9e-01
28 TCGA Prostate Adenocarcinoma 0.0418 0.0231 5.3e-04 0.032 0.035 0.027 NA 0.029 2.4e-04 1.4e-04 7.2e-04 NA 5.1e-04
29 TCGA Thyroid Carcinoma 0.0440 0.0260 7.1e-04 0.035 0.024 0.025 NA 0.024 2.3e-04 2.0e-03 1.5e-03 NA 1.9e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
Bipolar Disorder (2018) 0.8 1.3 3.3 0.6 1.4 0.4 1.8 1.3 1.0 0.2 1.2 1.8 0.1 0.9 1.1 0.9 1.0 1.5 0.9 1.0 1.7 1.4 1.2 0.9 -0.0 1.2 -1.3 0.0 0.3 1.3 1.7 1.5
Bipolar Disorder or Schizophrenia 1.3 3.2 8.4 -1.2 2.5 1.1 2.9 0.8 1.8 0.5 1.6 2.4 0.2 1.7 1.6 1.5 1.7 1.8 1.1 1.7 2.0 2.4 2.0 2.0 -0.6 1.8 -2.4 1.0 0.2 2.2 2.5 2.3
Depressed Affect (Nagel 2018) 0.3 0.6 2.6 0.2 0.2 1.6 0.2 -0.7 0.9 1.3 1.0 0.8 0.3 0.8 0.4 0.7 0.9 1.2 0.5 0.8 0.4 0.8 0.8 0.9 -0.7 0.4 -0.8 0.6 1.2 0.9 0.6 -0.0
Depression (Nagel 2018) 2.0 3.1 6.6 -2.4 1.8 1.4 1.5 1.2 1.7 1.9 2.0 2.4 1.2 1.7 1.3 1.6 1.7 2.0 2.0 1.5 1.4 2.2 1.8 2.2 -0.8 1.6 -1.9 1.7 0.2 2.6 1.6 1.6
Intelligence (Savage-Jansen 2018) 0.2 0.7 8.7 0.9 -0.1 -1.2 0.4 -0.3 -0.3 -0.8 -1.0 -0.2 -3.0 -0.4 -0.6 -0.3 -0.3 -0.2 -1.5 -0.4 -0.4 0.1 -0.1 0.3 1.0 -0.1 0.0 -0.8 0.1 -0.8 0.7 -0.1
Neuroticism (Nagel 2018) 3.1 7.2 12.0 -0.9 2.6 2.1 2.1 1.6 3.1 3.5 3.3 3.1 1.7 3.1 2.7 2.9 3.1 3.2 2.2 3.1 2.1 3.1 3.1 2.9 -1.1 3.1 -3.0 2.5 2.3 3.0 2.5 2.4
Schizophrenia (2018) 1.0 2.1 5.3 -2.1 2.1 1.0 2.3 -0.0 1.5 0.4 1.1 1.8 0.2 1.4 1.1 1.2 1.5 1.3 0.6 1.4 1.2 2.0 1.6 1.9 -0.8 1.3 -2.0 1.2 0.0 1.8 1.8 1.7
Schizophrenia vs Biploar Disorder 0.2 0.3 2.3 -1.5 0.2 0.3 0.2 0.1 0.5 0.7 0.5 -0.1 0.6 0.4 0.8 0.3 0.5 0.4 0.5 0.7 0.8 0.3 0.5 0.5 0.8 -0.1 -0.4 0.8 0.6 0.3 0.4 0.2
Worry (Nagel 2018) 4.9 10.3 19.2 -2.6 3.2 2.5 2.7 2.5 3.6 3.9 4.4 3.8 2.3 3.8 3.3 3.3 3.7 3.7 2.7 3.7 2.0 3.6 3.5 3.2 -0.8 3.9 -3.6 3.3 1.5 3.8 2.3 3.0
Alzheimer’s Disease (in mother) 3.2 3.7 11.1 0.8 -2.1 -0.8 -3.0 -1.4 -1.5 -2.2 -1.8 -2.1 -1.5 -1.6 -1.6 -1.6 -1.5 -2.1 -1.1 -1.6 -2.2 -1.9 -1.9 -1.8 1.7 -2.7 2.0 -1.9 -0.9 -2.0 -2.6 -3.3
Alzheimer’s Disease (in father) 0.7 0.8 4.0 -1.0 -1.0 -0.9 -0.8 1.0 -0.3 -1.7 -1.0 -0.8 1.1 -0.4 -0.8 -0.0 -0.3 -0.2 -0.2 -0.3 -1.2 -0.4 -0.3 0.2 0.3 -0.9 0.2 -2.0 -1.2 -0.4 -0.6 -1.4
Alzheimer’s Disease (including proxy) 6.4 9.3 20.1 0.1 -3.2 -2.0 -3.3 -1.2 -2.8 -3.8 -3.3 -3.2 -1.5 -3.0 -3.5 -2.6 -2.9 -3.2 -2.2 -3.2 -3.8 -3.0 -3.0 -2.3 2.2 -4.1 3.0 -4.5 -3.2 -2.8 -3.3 -4.4
Crohns Disease (2017) 0.8 1.8 7.1 -0.0 -0.9 -0.1 -0.5 -1.2 -1.5 -1.4 -1.3 -1.1 -0.3 -1.6 -1.2 -1.4 -1.6 -1.1 -2.7 -1.6 -1.3 -1.4 -1.4 -1.5 0.4 -1.7 1.5 -1.4 -1.9 -1.0 -1.2 -1.1
Irritable Bowel Disease (IBD) 0.2 0.4 2.2 -0.8 0.3 1.5 0.6 -0.0 0.4 0.7 0.6 0.7 1.3 0.3 0.8 0.4 0.3 0.6 -0.9 0.2 0.6 0.2 0.4 0.3 -0.8 0.2 -0.2 -0.4 0.1 0.9 0.4 0.0
Ulcerative Colitis (UC) 1.4 2.6 7.6 -1.0 1.1 2.7 1.2 0.9 1.7 2.5 2.1 2.0 2.2 1.6 2.0 1.5 1.7 1.8 1.0 1.5 1.7 1.3 1.6 1.3 -0.8 1.7 -1.2 0.8 1.3 2.3 1.2 0.7
Major Depression (MDD) 0.1 0.2 0.8 0.4 -0.5 0.3 -0.5 0.7 -0.2 -0.5 0.2 0.1 -0.9 -0.2 -0.4 -0.4 -0.2 -0.3 -0.7 -0.3 0.0 -0.2 -0.2 0.1 0.4 -0.2 0.1 0.0 -0.7 0.1 -0.6 -0.4
Reaction Time 1.5 2.9 9.9 1.6 -2.2 0.3 -3.1 -2.7 -1.4 -1.5 -1.6 -2.0 2.2 -1.4 -0.9 -1.4 -1.5 -1.0 -1.3 -1.2 -1.3 -1.9 -1.6 -1.1 -0.2 -2.1 2.3 -1.6 -0.3 -1.1 -1.7 -2.3
Verbal and Numeric Reasoning (VNR) 0.3 0.7 5.0 -0.4 0.0 -2.0 0.4 0.3 -0.3 -1.1 -0.6 -0.2 -2.2 -0.3 -0.3 -0.4 -0.3 -0.5 -1.9 -0.1 -0.6 -0.1 -0.3 -0.1 1.4 -0.4 0.3 0.0 -0.6 -0.9 -0.0 0.1
Breast Cancer 0.4 1.0 3.3 -0.3 1.1 1.4 1.2 1.6 0.6 1.8 0.9 1.2 0.2 0.6 0.6 0.5 0.6 1.0 1.7 0.6 0.6 0.8 0.8 0.4 -0.5 1.1 -0.9 1.1 0.6 0.9 0.9 1.6
Ovarian Cancer 0.1 0.2 1.0 -0.3 0.3 0.4 -0.4 1.0 0.1 -0.1 0.7 0.4 -1.0 0.2 -0.2 0.2 0.1 -0.2 0.6 0.0 -0.3 -0.0 0.1 -0.3 0.4 0.0 -0.1 0.5 -0.6 0.4 -0.3 0.6
Prostate Cancer 0.6 0.8 3.6 -1.4 -0.0 -1.4 -0.7 -0.7 -0.9 -1.1 -0.6 -0.6 -0.8 -1.0 -0.9 -1.0 -0.9 -0.8 -0.1 -0.9 -0.7 -0.7 -0.9 -0.9 0.9 -0.9 0.4 -0.9 -1.9 -0.5 -0.7 -0.3
Age at First Birth 1.0 1.5 6.2 -2.5 1.3 -1.9 2.4 1.3 0.8 0.8 0.8 1.0 1.5 0.6 0.9 0.7 0.6 0.8 1.1 0.7 1.1 1.1 1.0 0.8 0.3 1.2 -1.1 0.5 -0.5 0.9 1.7 2.1
Bipolar Disorder (2011) 4.3 4.2 9.7 0.2 2.1 -0.6 2.6 2.1 2.1 1.3 1.7 2.6 0.6 1.9 2.0 2.2 1.9 2.3 2.2 2.0 2.4 2.3 2.4 2.5 -0.8 2.5 -2.3 0.6 1.3 2.0 3.1 2.6
Body Mass Index (BMI) (2010) 6.6 9.0 16.5 1.8 -3.7 -0.8 -3.4 -3.4 -3.1 -3.4 -3.6 -3.9 -0.8 -3.1 -2.8 -2.9 -3.0 -3.2 -2.7 -2.9 -3.2 -3.4 -3.3 -2.8 1.6 -3.3 3.1 -2.5 -1.1 -3.4 -3.1 -4.1
Coronary Artery Disease (CAD) 0.8 1.0 3.9 0.2 0.6 1.5 -0.1 1.3 0.6 1.4 0.7 1.2 -0.5 0.7 1.1 0.3 0.8 0.8 2.0 0.7 0.9 0.8 0.8 0.4 -0.1 1.2 -0.6 1.4 1.5 0.7 1.4 1.6
Crohns Disease (2012) 0.4 0.7 4.6 -1.6 1.1 -0.2 2.1 1.1 0.4 -0.4 0.3 1.0 -0.0 0.3 0.4 0.5 0.3 1.1 -0.5 0.4 0.8 0.7 0.6 0.6 -0.6 -0.2 -0.7 0.3 -0.2 1.2 1.2 1.2
Mean Putamen Volume 0.2 0.3 3.2 1.8 -0.3 -0.5 0.2 -1.1 -0.1 -0.7 -0.4 -0.4 -0.3 -0.1 -0.2 0.1 -0.1 0.1 -0.3 0.1 0.1 -0.2 -0.1 -0.0 0.6 -0.2 0.6 -0.6 0.4 -0.3 -0.2 -0.6
Fasting Glucose 1.8 2.1 5.0 1.1 -1.2 -0.8 -2.1 -1.9 -0.7 -2.1 -1.7 -1.7 1.8 -1.6 -0.1 -1.2 -1.6 -1.9 -1.4 -1.2 -0.1 -1.8 -1.0 -0.8 0.0 -1.8 1.8 -1.3 -0.4 -1.8 -1.3 -2.2
HbA1C 0.4 0.5 3.0 1.1 0.4 0.2 -0.1 1.0 0.6 0.2 -0.2 -0.2 0.1 0.7 1.1 0.6 0.7 0.4 0.5 1.0 0.3 0.5 0.5 0.8 -0.2 0.3 -0.6 0.5 1.7 -0.2 1.1 0.7
HDL Cholesterol 0.6 0.9 2.3 1.0 -0.9 0.5 -1.5 0.2 -0.9 -0.3 -0.5 -0.8 -1.2 -0.8 -0.6 -1.1 -0.9 -1.2 -0.4 -0.9 -0.9 -1.2 -1.0 -1.1 0.7 -1.0 1.5 -1.2 -0.9 -0.6 -1.2 -1.3
LDL Cholesterol 1.6 2.6 5.1 -1.4 1.1 0.9 0.6 1.2 2.0 1.6 1.6 1.7 0.0 2.0 1.8 2.3 2.0 1.5 1.8 2.0 1.2 1.6 1.9 2.0 -0.6 1.8 -1.9 1.6 2.0 1.5 1.4 0.9
Lupus 0.2 0.3 2.1 1.4 -0.3 -0.4 -0.2 0.2 -0.1 1.0 -0.1 0.2 -1.0 -0.1 -0.2 0.2 -0.2 0.2 0.3 -0.2 -0.2 -0.1 -0.1 -0.1 1.4 0.3 0.6 0.1 0.2 -0.3 0.2 0.6
Neuroticism (2016) 1.0 1.4 5.2 -1.5 1.2 2.3 0.7 1.8 1.1 1.1 1.5 1.2 0.0 1.1 1.1 0.7 1.1 1.4 0.9 1.0 0.9 1.3 1.1 0.9 -0.2 1.4 -1.2 1.4 0.3 1.3 0.7 0.9
Primary Biliary Cirrhosis 0.7 1.1 3.7 0.4 0.5 1.9 0.6 0.4 0.8 1.8 1.1 1.3 -1.0 0.8 0.9 0.8 0.9 1.0 1.2 0.7 0.6 0.8 0.9 0.6 -1.6 1.1 -1.0 0.7 1.4 1.0 1.0 0.9
Rheumatoid Arthritis 2.6 3.6 7.4 2.7 -1.6 -1.5 -1.3 -1.9 -2.2 -1.4 -2.2 -1.7 -0.7 -2.2 -2.4 -2.3 -2.2 -1.9 -2.4 -2.3 -2.3 -2.1 -2.0 -2.1 1.7 -1.2 1.9 -2.0 -1.3 -2.3 -1.0 -0.6
Schizophrenia (2014) 3.9 8.7 13.8 -2.6 3.6 2.1 3.7 1.4 3.2 1.8 2.7 3.7 0.6 3.0 2.9 2.8 3.1 3.1 2.9 3.0 3.0 3.7 3.4 3.5 -1.7 3.0 -3.7 2.6 1.7 3.3 3.6 3.3
Triglycerides 0.3 0.5 1.3 0.2 -0.9 -0.8 -1.1 -1.1 -0.6 -0.8 -0.7 -1.1 -0.9 -0.7 -0.5 -0.4 -0.6 -0.9 -0.6 -0.5 -0.5 -0.6 -0.5 -0.4 -0.8 -0.8 0.3 -0.5 0.6 -1.0 -0.2 -0.8
Type 2 Diabetes (T2D) (2012) 0.3 0.3 5.1 -0.3 -0.2 -1.1 0.4 -0.2 -0.2 0.0 -0.4 0.0 -2.3 -0.1 0.0 -0.2 -0.1 -0.3 -0.7 -0.1 -0.0 0.0 -0.1 0.3 1.4 0.4 -0.2 0.0 -0.0 -0.1 0.3 0.2
Ulcerative Colitis 1.2 1.7 4.3 -1.1 0.8 2.0 0.7 1.3 1.3 1.5 1.4 1.5 2.1 1.2 1.3 1.1 1.3 1.1 1.1 1.1 1.5 1.0 1.3 1.4 -1.9 1.4 -0.9 0.1 1.1 1.7 1.5 0.7
Blood Eosinophil Count 0.2 1.8 7.0 0.9 -0.9 -2.0 -2.6 -0.4 -1.1 -0.3 -1.1 -0.9 -0.8 -0.9 -1.2 -0.4 -1.0 -1.3 -1.2 -0.9 -1.8 -1.9 -1.4 -1.1 1.5 -1.1 1.8 -1.4 -1.2 -1.1 -1.9 -1.8
Blood Platelet Count 1.7 20.3 60.5 3.3 -4.5 -1.3 -5.6 -3.0 -4.6 -7.8 -4.3 -5.1 1.3 -4.7 -4.8 -4.6 -4.7 -4.5 -3.4 -4.4 -4.5 -4.8 -4.8 -3.1 0.9 -5.0 5.3 -5.6 -4.3 -3.1 -4.7 -5.9
Blood Red Count 0.9 8.3 15.4 1.3 -3.3 -1.4 -3.9 -2.3 -2.9 -3.2 -3.1 -3.2 -1.1 -2.9 -2.1 -3.3 -2.9 -3.1 -2.8 -2.9 -3.0 -3.3 -3.1 -3.2 2.1 -3.2 3.1 -2.6 -1.1 -3.5 -3.2 -3.7
Blood White Count 10.6 78.5 121.0 6.3 -10.3 -6.1 -11.0 -5.5 -9.2 -9.6 -9.9 -9.8 -1.6 -9.3 -9.1 -9.1 -9.3 -9.7 -8.8 -9.1 -9.6 -10.2 -9.8 -8.5 3.8 -9.5 9.8 -9.7 -5.8 -9.1 -9.3 -10.6
Heel T-Score 0.4 3.2 10.6 1.0 -1.5 -3.3 -1.6 -1.2 -1.8 -1.9 -2.6 -1.7 0.6 -2.0 -1.3 -1.7 -2.0 -1.7 -2.3 -1.8 -1.6 -2.0 -1.8 -1.4 0.9 -1.6 1.8 -2.8 -1.2 -2.1 -0.4 -1.0
BMI 4.6 26.6 46.4 3.4 -6.5 -2.4 -5.0 -3.5 -5.5 -6.7 -6.7 -5.7 -1.7 -5.7 -5.2 -5.1 -5.5 -5.1 -5.1 -5.2 -4.9 -5.6 -5.6 -4.3 2.6 -6.8 4.8 -6.8 -2.5 -5.2 -4.2 -6.7
Height 0.1 1.2 3.6 1.4 -1.5 0.8 -1.4 -1.1 -1.3 -0.2 -1.0 -1.1 0.4 -1.3 -0.6 -1.3 -1.3 -0.5 -0.2 -1.0 -0.3 -1.6 -1.4 -1.4 -1.0 -0.2 1.9 -0.9 0.3 -1.3 -1.0 -1.4
Waist Hip Ratio (WHR) 0.2 1.1 4.5 -0.2 0.6 -0.6 -0.5 0.4 1.3 2.1 1.3 1.1 -0.6 1.3 1.2 1.2 1.3 1.1 0.4 1.3 1.0 0.8 1.1 0.8 -0.3 1.6 -0.0 1.0 1.7 0.5 0.3 0.2
Systolic Blood Pressure 0.7 3.3 6.6 -1.8 1.9 -0.2 1.6 0.3 1.9 1.8 1.1 2.0 2.5 1.8 2.0 1.8 1.8 2.6 2.0 2.0 1.5 2.0 2.0 2.1 -0.3 2.0 -1.5 2.0 1.9 0.9 2.5 2.4
Smoking Status 0.6 1.5 4.5 2.1 -1.2 -2.0 -1.0 -0.6 -1.0 -0.9 -1.3 -1.0 -1.3 -1.2 -1.7 -0.7 -1.2 -1.0 -0.6 -1.0 -0.5 -1.0 -1.1 -1.0 1.2 -1.1 1.4 -2.1 -1.3 -0.9 -0.8 -1.1
Allergy or Eczema 0.3 0.8 2.8 1.0 -0.9 -0.7 -1.2 -1.2 -1.0 -1.7 -1.5 -1.0 0.4 -1.1 -0.4 -0.9 -1.0 -0.7 -0.3 -0.9 -0.3 -1.0 -1.0 -0.4 0.5 -0.6 0.8 -1.6 -0.2 -1.2 -0.1 -0.7
Cardiovascular Disease 0.6 2.1 3.9 -0.7 1.5 0.5 1.5 1.7 1.5 1.1 0.9 1.5 1.8 1.5 1.7 1.6 1.5 1.6 1.2 1.7 1.2 1.7 1.6 1.8 0.5 1.3 -1.4 1.4 1.4 1.1 2.0 1.7
Hypothyroidism (self reported) 0.6 1.4 7.2 1.3 -0.6 -0.2 -1.5 -1.1 -1.1 -0.6 -0.8 -1.1 -2.0 -1.1 -0.8 -1.2 -1.1 -1.2 -1.7 -1.0 -0.6 -1.1 -1.0 -1.3 2.7 -1.0 1.6 0.1 -0.7 -1.3 -0.9 -0.3
Respiratory disease 0.1 0.2 2.4 0.5 0.3 1.6 -0.0 -0.4 -0.2 0.5 0.3 0.1 1.2 -0.1 -0.0 -0.6 -0.1 0.3 -0.3 -0.2 0.1 0.1 -0.2 0.1 0.0 0.3 -0.0 -0.6 -0.4 0.2 0.1 -0.1
Type 2 Diabetes (T2D) (2018) 2.4 4.5 8.4 2.1 -2.5 -1.4 -1.8 -1.5 -2.2 -2.3 -2.5 -2.3 0.1 -2.1 -2.2 -2.1 -2.1 -2.2 -2.6 -2.1 -2.2 -2.2 -2.2 -2.0 0.7 -2.9 2.1 -2.5 -0.8 -2.3 -2.0 -2.7
Lung FEV1/FVC ratio 0.2 0.9 2.5 -0.7 0.7 -0.6 1.2 0.7 1.0 -0.6 0.4 0.6 0.2 0.9 0.9 1.6 0.9 0.8 1.4 1.1 1.4 1.0 1.1 1.2 -0.5 -0.1 -1.0 -0.2 0.5 1.3 1.2 0.7
Lung FVC 0.1 0.7 2.5 1.6 -0.1 -1.0 -0.5 -0.4 -1.1 -0.4 -1.0 -0.3 1.2 -1.0 -1.0 -0.8 -1.2 -0.6 -0.5 -1.1 -1.0 -1.0 -0.9 -0.8 0.4 0.0 1.2 -0.8 -1.0 -0.6 -0.0 0.4
Neuroticism 2.1 5.0 8.2 -0.8 1.9 1.1 1.5 0.9 2.8 2.5 2.6 2.3 1.4 2.7 2.3 2.4 2.7 2.8 2.2 2.9 1.6 2.7 2.7 2.5 -0.4 2.8 -2.4 1.9 2.2 2.5 2.2 1.9
Chronotype (morning person) 4.4 10.3 16.4 -0.8 3.1 2.8 1.9 3.1 3.7 3.8 4.0 3.7 2.2 3.7 3.6 3.5 3.7 3.7 3.3 3.7 2.5 3.4 3.5 2.9 -0.2 3.7 -3.3 3.4 2.8 3.6 2.8 2.9
Hair Pigment 0.1 1.7 6.8 -0.1 1.0 2.6 0.7 0.1 1.4 1.0 1.7 1.5 1.5 1.3 1.2 1.1 1.3 1.5 1.9 1.3 1.2 1.2 1.3 0.7 -1.2 1.0 -1.4 1.5 1.1 1.9 0.4 0.6
Tanning 0.3 3.1 9.4 0.3 -1.1 -3.1 -1.0 -0.0 -2.0 -1.7 -2.1 -1.8 1.1 -2.0 -2.3 -1.4 -2.0 -2.0 -1.0 -2.0 -1.3 -1.7 -1.9 -1.6 2.3 -0.9 2.1 -1.5 -2.5 -2.2 -1.2 -0.7
Hand grip strength (left) 2.2 5.8 10.4 0.3 -2.2 -2.5 -2.3 -1.7 -2.8 -2.3 -2.8 -2.5 -0.7 -2.7 -3.2 -2.3 -2.7 -2.6 -1.6 -2.8 -2.9 -2.6 -2.7 -2.4 1.6 -1.6 2.8 -2.9 -3.1 -2.3 -2.3 -2.1
Number of treatments/medications taken 0.1 0.2 0.9 1.0 0.3 0.5 0.4 -0.1 0.4 0.2 0.6 0.3 0.5 0.5 0.3 0.2 0.5 0.6 -0.6 0.6 0.5 0.3 0.4 0.5 -0.4 0.1 -0.1 0.3 0.5 0.5 0.3 0.3
Average weekly spirits intake 0.4 0.5 3.1 0.5 -0.5 -1.2 -0.1 -0.9 -0.6 -1.8 -1.2 -1.1 0.6 -0.7 -0.3 -0.6 -0.7 -0.2 -0.4 -0.2 0.3 -0.2 -0.4 0.3 0.2 -0.9 0.0 -1.4 -0.2 -0.6 1.0 -0.1
Sensitivity / hurt feelings 1.5 2.5 5.1 -0.4 1.6 -0.9 1.6 0.9 1.8 1.8 1.5 1.6 1.0 1.8 1.6 1.8 1.8 1.7 0.6 1.9 1.3 1.8 1.8 1.7 -0.1 2.2 -1.2 1.9 2.2 1.1 2.1 1.7
Frequency of depressed mood in last 2 weeks 0.3 0.4 1.5 -0.5 0.5 -0.2 1.0 1.2 0.4 1.1 0.7 1.2 0.3 0.3 -0.1 0.4 0.3 0.8 -0.3 0.1 -0.2 0.7 0.5 0.6 0.7 0.3 -0.6 0.0 -0.2 0.9 0.9 0.9
Hearing difficulty/problems: Yes 0.5 0.8 8.8 -0.5 -0.1 1.9 0.1 1.0 0.2 1.0 0.2 0.4 3.0 0.2 0.5 -0.2 0.3 0.7 1.0 0.3 0.6 0.4 0.3 0.7 -1.7 0.3 -0.4 0.0 1.2 0.6 1.1 0.0
Relative age of first facial hair 0.6 1.3 5.6 -1.1 1.5 -0.0 1.8 -0.3 0.9 1.1 0.8 1.1 0.3 0.9 0.8 0.9 1.0 1.4 0.8 1.0 0.7 1.5 1.2 1.1 0.4 1.0 -1.7 0.8 -0.0 1.3 1.8 2.4
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 2.9 -0.0 0.4 -1.7 0.2 0.2 0.1 -0.6 -0.3 0.2 0.7 0.1 -0.2 0.2 0.2 0.4 -0.1 0.2 0.3 0.5 0.3 0.8 0.9 0.3 -0.6 -1.0 -0.6 0.4 1.3 0.7
Ever used hormone-replacement therapy (HRT) 7.6 9.7 15.7 -0.3 3.2 2.2 2.7 0.8 3.4 3.0 2.9 3.2 0.5 3.4 3.7 3.3 3.5 3.6 2.8 3.6 3.4 3.5 3.7 3.5 -3.1 2.9 -3.4 2.6 3.6 3.3 4.0 3.0
Ever had hysterectomy (womb removed) 0.4 0.4 2.9 -0.4 0.7 0.1 0.9 0.2 0.4 0.2 0.6 0.6 1.7 0.4 -0.0 0.3 0.4 0.7 1.1 0.4 0.4 0.7 0.5 0.7 -0.1 0.9 -0.6 1.0 -0.1 0.8 0.5 0.6
Systolic blood pressure, automated reading 0.6 1.9 5.4 -0.7 1.2 -0.4 1.7 0.4 1.5 1.5 0.6 1.4 1.1 1.4 1.5 1.5 1.4 1.9 0.6 1.6 1.0 1.6 1.6 2.0 -0.3 1.1 -1.5 0.9 1.7 0.7 2.3 1.7
Eye problems/disorders: Diabetes related eye disease 0.3 0.4 3.0 -0.3 -0.0 -0.2 0.9 1.7 0.2 -0.7 0.4 1.1 1.1 0.4 -0.2 0.3 0.4 0.5 0.9 0.0 0.1 0.5 0.3 0.1 -0.3 0.2 -0.6 -0.9 -0.3 0.6 0.3 0.3
Angina 0.9 1.2 4.4 -0.5 1.4 2.1 1.2 -0.2 1.0 0.9 1.4 1.5 0.6 1.0 1.0 0.7 1.1 1.3 0.9 1.1 1.2 1.2 1.1 0.8 -0.1 0.9 -1.2 0.6 0.4 1.3 1.1 1.1
Medication for hormone replacement therapy 0.6 0.6 2.4 0.1 -0.4 -0.6 0.4 0.2 -1.0 -0.9 -0.6 -0.5 -1.5 -0.9 -0.9 -1.1 -0.9 -1.1 -1.0 -1.0 -0.2 -0.7 -0.7 -1.0 -0.9 -1.0 0.5 -1.0 -0.8 -0.2 -0.3 -0.2
Vitamin and mineral supplements 0.3 0.4 1.7 -0.1 0.2 -0.2 -1.1 -1.0 -0.2 -0.9 -0.9 -0.8 -1.3 -0.5 -0.4 -0.6 -0.4 -0.7 0.9 -0.5 -0.5 -0.0 -0.2 0.1 0.1 -0.6 0.2 -0.6 -0.3 -0.6 -0.0 -0.7
Supplements: Zinc 0.5 0.5 2.3 0.8 -0.7 0.4 -0.7 1.3 -0.5 -0.7 -0.2 -0.1 -0.1 -0.5 -0.9 -0.1 -0.5 -0.7 -0.5 -0.8 0.1 -0.7 -0.6 -0.7 -1.4 -0.3 0.9 -0.9 0.1 -0.5 -1.1 -1.5
Medication: Co-codamol 0.2 0.3 1.2 1.1 -0.9 0.5 -0.8 -0.5 -0.1 0.3 -0.3 -0.1 1.0 -0.2 -0.0 0.0 -0.2 0.6 -0.7 -0.1 0.1 -0.4 -0.2 0.2 0.4 -0.2 0.8 -0.6 0.8 -0.4 -0.0 -0.8
Medication: Metformin 0.6 0.8 3.3 0.6 -0.9 -1.8 -0.6 -0.9 -0.7 -1.2 -0.8 -0.8 -0.6 -0.6 -0.9 -0.6 -0.6 -0.7 -1.7 -0.7 -1.0 -0.7 -0.7 -0.3 0.4 -1.1 0.9 -1.5 -0.5 -0.6 -0.7 -1.3
Diabetes (father) 0.4 0.5 1.2 0.4 -0.9 0.3 -0.0 0.4 -0.8 -0.2 -0.6 -0.8 -0.3 -0.7 -0.5 -0.8 -0.7 -1.0 -1.1 -0.7 -0.7 -0.9 -0.9 -0.7 0.5 -0.7 0.7 -0.9 -0.5 -0.5 -0.8 -1.0
Diabetes (mother) 1.0 1.3 3.7 1.7 -0.7 -0.9 -1.8 -1.9 -1.1 -1.0 -1.0 -1.4 -1.5 -1.0 -0.8 -1.7 -1.0 -1.3 -0.5 -0.9 0.0 -1.0 -1.0 -1.0 0.5 -1.2 0.9 -1.1 -1.0 -1.3 -1.0 -0.9
Severe depression (siblings) 0.4 0.5 1.4 0.7 -0.8 0.7 -1.0 0.1 -0.8 -0.6 -0.6 -1.1 0.4 -0.7 -0.3 -0.9 -0.6 -1.1 -0.1 -0.7 -0.6 -0.7 -0.8 -0.3 -1.2 -0.6 0.6 -0.8 0.1 -0.7 -0.4 -0.7
Pack years adult smoking proportion 0.3 0.5 2.2 0.0 0.2 0.3 -0.5 -1.5 0.8 0.6 0.5 0.5 0.4 0.8 0.6 0.5 0.8 1.0 -1.1 0.8 0.4 0.6 0.7 0.6 0.1 0.9 -0.4 1.1 1.3 0.1 0.4 -0.0
Impedance of leg (right) 0.6 3.0 11.7 -1.8 1.8 1.1 0.2 0.3 1.9 2.8 2.5 1.9 0.2 1.9 2.1 1.4 1.8 1.7 1.9 1.7 1.6 1.7 1.6 1.2 -0.7 2.2 -0.8 3.4 1.5 1.4 0.7 1.6
Leg fat-free mass (left) 2.8 14.6 30.0 3.0 -4.5 -2.8 -3.3 -2.3 -4.1 -5.2 -4.8 -4.6 -1.9 -4.1 -3.9 -3.7 -4.1 -4.1 -3.3 -3.8 -3.3 -4.2 -4.1 -3.3 1.9 -4.2 3.6 -5.5 -2.3 -4.0 -3.1 -4.6
Trunk fat percentage 3.3 13.1 24.4 2.8 -4.8 -1.7 -4.6 -2.9 -3.7 -4.1 -4.3 -4.3 -2.7 -3.7 -3.1 -3.6 -3.6 -3.9 -3.5 -3.5 -2.8 -4.1 -3.8 -3.1 2.0 -4.5 3.6 -4.1 -1.1 -3.7 -3.4 -4.9
Hand grip strength (right) 2.6 7.1 10.8 0.8 -2.4 -2.3 -2.4 -1.3 -3.1 -3.3 -3.1 -2.7 -0.9 -3.1 -3.2 -2.9 -3.1 -2.9 -1.4 -3.1 -3.1 -2.9 -3.0 -2.7 1.8 -2.2 3.0 -3.3 -3.1 -2.7 -2.5 -2.4
Townsend deprivation index at recruitment 0.4 0.5 2.0 0.5 0.8 -0.0 0.8 -1.4 0.7 0.7 1.0 0.4 -0.2 0.8 0.3 0.8 0.7 0.9 -0.7 0.8 0.5 0.6 0.7 0.1 1.1 0.6 -0.9 0.5 -0.2 1.0 -0.2 0.7
Current tobacco smoking 0.2 0.3 2.5 -0.0 -0.4 -1.6 -0.6 -0.9 -0.3 -0.4 -0.5 -0.3 0.0 -0.4 -0.7 -0.1 -0.4 -0.1 -0.9 -0.4 -0.0 -0.1 -0.4 0.0 0.4 -0.1 0.7 -0.4 -0.6 -0.1 -0.4 -0.6
Average weekly fortified wine intake 0.4 0.5 3.8 -0.5 -0.6 -0.4 -0.6 -1.9 -0.5 -1.3 -0.6 -1.1 -0.2 -0.5 -0.5 -0.5 -0.5 -0.4 -0.7 -0.4 -0.7 -0.5 -0.5 -0.5 0.3 -1.1 0.3 -0.2 -0.3 -0.5 -0.7 -1.0
Maternal smoking around birth 1.0 1.4 5.3 -1.2 -1.1 0.9 -1.6 -0.1 -1.1 -1.2 -1.2 -0.8 -0.2 -1.0 -1.7 -0.9 -1.0 -1.3 -0.4 -1.4 -1.6 -1.2 -1.3 -0.8 -1.0 -1.1 1.0 -0.5 -0.9 -0.6 -1.8 -2.3
Fed-up feelings 0.2 0.3 3.7 1.9 -0.4 0.6 -0.0 -0.7 0.4 0.3 0.4 0.2 0.8 0.3 0.2 0.4 0.3 0.5 0.1 0.4 0.2 -0.1 0.2 0.0 -0.2 0.0 -0.0 -0.5 1.4 0.0 0.1 -0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 2.0 2.6 6.4 -2.2 1.9 1.0 1.6 0.8 1.8 1.6 1.9 2.4 -0.4 1.6 1.4 1.5 1.7 2.1 1.4 1.5 1.4 2.0 1.8 1.8 -0.7 1.4 -1.8 1.1 0.2 2.5 1.6 1.4
Relative age voice broke 0.5 0.8 6.4 -0.1 0.9 -0.2 0.7 -0.4 0.7 2.5 1.0 0.8 0.5 0.9 1.1 0.8 0.8 0.8 0.3 1.0 0.8 0.7 0.8 0.6 0.7 0.8 -0.5 0.6 0.5 0.9 0.8 1.3
Taking other prescription medications 0.9 1.3 2.7 1.0 1.2 0.6 0.6 -0.3 1.3 1.4 1.5 1.0 0.1 1.4 1.4 1.0 1.4 1.3 -0.3 1.5 1.2 1.2 1.3 1.0 -0.4 1.1 -1.1 1.6 1.5 0.7 1.1 1.3
Age when periods started (menarche) 4.7 11.4 21.8 0.3 3.1 2.3 2.7 1.6 3.7 4.7 3.6 3.4 2.8 3.9 3.0 4.2 3.8 4.1 3.9 3.9 3.1 3.4 3.7 3.6 -2.7 4.1 -2.5 3.3 3.6 3.2 3.3 3.4
Bilateral oophorectomy (both ovaries removed) 0.1 0.1 0.4 -0.7 0.0 0.3 0.5 0.4 -0.0 -0.1 0.0 0.3 -0.6 -0.1 0.2 -0.2 -0.1 0.1 -0.5 -0.1 -0.6 -0.0 -0.1 0.0 0.5 0.4 -0.3 -0.4 -0.6 0.3 0.1 -0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.6 1.4 5.2 0.1 -1.1 -1.8 -0.9 -0.8 -1.2 -1.1 -1.9 -1.2 0.8 -1.4 -1.0 -1.1 -1.4 -1.1 -1.0 -1.2 -1.0 -1.3 -1.1 -0.6 0.1 -1.5 1.0 -2.3 -0.8 -1.2 -0.4 -1.5
Tinnitus: Yes, but not now, but have in the past 2.1 2.2 9.1 0.5 -1.5 -0.9 -3.0 -1.4 -1.4 -2.1 -1.4 -2.0 -1.0 -1.3 -1.4 -1.4 -1.3 -1.9 -1.3 -1.4 -1.4 -1.6 -1.5 -1.1 -0.3 -1.3 1.5 -1.3 -0.9 -1.2 -1.7 -1.9
Qualifications: CSEs or equivalent 1.1 1.5 4.9 1.8 -1.5 0.1 -1.8 -0.8 -0.8 -0.7 -0.7 -1.2 0.6 -0.9 -1.2 -0.9 -0.8 -1.0 -2.2 -0.9 -1.6 -1.4 -1.1 -1.3 0.3 -1.1 1.5 -1.4 -0.2 -0.9 -1.7 -2.0
Serious illness, injury or assault to yourself 2.0 2.4 7.5 1.2 -2.2 -0.2 -1.4 -1.4 -1.5 -2.2 -1.9 -1.3 -0.6 -1.6 -1.8 -1.3 -1.4 -1.2 -1.2 -1.5 -1.6 -1.7 -1.6 -1.5 0.6 -2.2 1.5 -1.8 -0.5 -1.1 -1.9 -2.7
High blood pressure 1.4 4.0 6.4 -0.4 1.9 1.7 1.8 1.1 2.3 2.2 2.0 2.2 0.9 2.4 2.3 2.2 2.4 2.3 1.6 2.4 2.0 2.3 2.3 2.2 0.4 2.0 -2.5 2.5 2.0 1.7 2.0 2.0
Hayfever, allergic rhinitis or eczema 0.1 0.2 1.7 0.3 -0.4 -0.3 -0.3 -0.5 -0.5 -1.3 -0.7 -0.4 0.8 -0.5 -0.1 -0.4 -0.5 -0.2 -0.2 -0.4 -0.0 -0.5 -0.4 0.1 0.1 -0.0 0.2 -0.9 -0.0 -0.5 0.3 -0.2
Multivitamins +/- minerals 0.3 0.3 2.7 -0.7 -0.1 0.5 0.7 1.6 0.3 0.6 1.0 0.7 0.4 0.6 0.2 0.9 0.6 0.5 -0.4 0.5 0.1 0.1 0.3 0.1 -0.0 0.8 -0.3 0.6 -0.0 0.5 -0.3 0.3
Stomach or abdominal pain in last month 1.8 2.3 6.0 -1.8 1.2 -0.0 1.2 1.3 1.8 0.5 1.2 1.7 0.5 1.5 1.4 1.7 1.6 1.8 0.7 1.6 0.9 1.9 1.7 1.9 -2.4 1.6 -1.9 1.2 1.5 1.4 2.0 1.3
Supplements: Glucosamine 0.2 0.3 1.5 0.9 -0.6 0.5 -0.9 -1.2 -0.3 -0.8 -0.5 -0.7 1.0 -0.0 0.0 -0.2 0.0 0.0 1.0 0.1 0.0 -0.2 -0.1 -0.2 -0.5 -0.1 -0.2 -0.8 0.6 -0.0 0.2 -0.3
Diverticular disease/diverticulitis (self-reported) 0.2 0.2 1.7 -0.1 0.2 -1.3 1.2 -1.0 0.1 -0.1 0.3 0.1 0.2 0.1 -0.3 0.2 0.0 -0.2 -0.8 0.1 -0.1 0.1 0.1 -0.1 0.1 -0.1 -0.2 -0.1 -0.1 0.3 0.3 0.8
Medication: Atenolol 2.8 3.5 9.6 -2.4 1.6 3.1 1.4 0.0 2.1 1.3 1.9 2.0 0.5 2.0 2.1 2.1 2.0 2.1 1.8 1.9 1.9 2.0 2.0 2.0 -1.9 1.7 -2.2 2.5 1.5 1.6 0.9 0.7
Medication: Levothyroxine sodium 1.1 1.9 6.1 1.7 -1.1 0.2 -1.0 -0.3 -1.5 -1.5 -1.3 -1.3 -1.4 -1.6 -1.3 -1.7 -1.6 -1.6 -2.0 -1.4 -0.9 -1.2 -1.4 -1.5 2.5 -1.3 1.4 -0.6 -1.1 -1.5 -0.7 -0.5
Sitting height 0.2 1.2 3.1 0.6 -1.4 -1.8 -1.3 -0.6 -1.0 -1.2 -1.3 -1.4 -0.7 -1.1 -0.8 -0.9 -1.1 -1.1 0.2 -0.8 -0.5 -1.4 -1.2 -1.0 -0.4 -0.9 1.7 -1.3 0.3 -1.4 -0.8 -1.4
Chronic bronchitis/emphysema (father) 1.2 1.5 3.6 1.9 -1.4 -0.4 -1.5 -0.9 -1.2 -0.4 -0.7 -0.9 -1.3 -1.0 -1.0 -1.2 -1.1 -1.2 -1.8 -1.0 -0.8 -1.5 -1.4 -1.5 1.0 -1.7 1.2 -1.2 -0.6 -0.7 -1.5 -1.4
High blood pressure (mother) 3.0 4.2 10.1 -0.8 1.7 1.3 1.1 0.9 2.5 1.6 1.8 1.5 0.0 2.5 3.2 2.4 2.4 2.0 2.6 2.8 2.5 2.0 2.4 2.1 -1.9 2.0 -2.1 2.2 2.9 1.2 2.0 1.6
Body mass index (BMI) 4.4 18.6 32.8 3.3 -5.2 -2.4 -4.1 -2.8 -4.7 -5.3 -5.5 -5.0 -1.7 -4.7 -4.3 -4.3 -4.6 -4.5 -4.7 -4.4 -4.0 -4.7 -4.6 -3.6 2.4 -5.5 3.9 -5.7 -2.2 -4.4 -3.4 -5.3
Impedance of leg (left) 0.5 2.4 9.4 -1.9 1.6 1.2 0.2 0.1 1.7 2.8 2.3 1.8 0.1 1.7 1.7 1.3 1.6 1.5 1.5 1.5 1.4 1.4 1.4 0.9 -0.4 1.9 -0.7 3.1 1.0 1.4 0.3 1.2
Leg predicted mass (left) 2.9 15.3 30.9 3.1 -4.6 -2.9 -3.4 -2.4 -4.2 -5.3 -4.9 -4.7 -1.9 -4.2 -4.0 -3.8 -4.2 -4.2 -3.4 -3.9 -3.4 -4.3 -4.2 -3.4 2.0 -4.3 3.7 -5.6 -2.4 -4.0 -3.2 -4.7
Trunk fat mass 4.3 18.5 32.6 3.4 -5.6 -2.3 -4.9 -3.3 -4.5 -5.1 -5.3 -5.1 -2.6 -4.5 -3.9 -4.3 -4.4 -4.5 -4.1 -4.2 -3.5 -4.8 -4.6 -3.7 2.1 -5.1 4.3 -5.2 -1.6 -4.5 -3.9 -5.7
Waist circumference 2.9 10.7 19.5 2.6 -4.3 -2.3 -4.0 -2.4 -3.4 -3.8 -4.1 -3.9 -1.3 -3.4 -3.0 -3.0 -3.3 -3.4 -3.5 -3.1 -2.6 -3.7 -3.5 -2.7 1.1 -3.8 3.2 -4.4 -1.1 -3.5 -2.8 -4.4
Number of incorrect matches in round 2.4 4.0 7.9 -1.6 2.4 1.4 2.1 2.4 1.8 2.2 1.9 2.2 2.8 2.0 2.2 1.8 1.9 2.0 2.2 1.9 1.5 2.0 1.9 2.0 -0.7 2.7 -1.6 2.1 0.7 1.7 2.1 2.6
Past tobacco smoking 1.0 1.8 16.4 -4.0 1.2 2.4 0.8 0.4 1.1 0.9 1.4 1.2 1.5 1.1 1.2 0.7 1.2 1.1 0.5 0.7 0.2 1.2 1.0 1.2 -1.3 0.8 -1.4 2.0 0.2 1.5 0.1 0.2
Alcohol usually taken with meals 0.4 0.6 2.0 -0.1 -1.0 0.8 -0.2 -0.3 -0.7 -0.1 -1.0 -1.1 1.1 -0.7 -0.3 -0.8 -0.7 -0.6 -0.8 -0.6 -1.4 -0.7 -0.8 -0.5 0.9 -0.6 0.9 0.1 0.3 -1.4 -0.7 -0.8
Nervous feelings 8.0 14.9 26.5 -2.6 4.4 3.7 3.4 1.9 4.4 4.3 5.1 4.5 2.8 4.4 4.3 3.8 4.4 4.3 3.0 4.3 3.3 4.3 4.3 3.6 -1.8 3.8 -4.3 4.3 2.1 4.7 3.1 3.9
Frequency of tenseness / restlessness in last 2 weeks 3.0 4.6 8.2 -1.8 2.3 1.9 1.6 1.8 2.4 1.8 2.7 2.7 -0.3 2.4 2.2 2.2 2.5 2.6 1.6 2.3 2.0 2.6 2.4 2.4 -0.9 2.2 -2.8 1.8 1.4 2.9 2.0 1.8
Hearing difficulty/problems with background noise 1.7 2.7 16.7 -2.6 0.8 2.3 0.6 2.1 1.4 1.8 1.4 1.2 4.1 1.4 1.2 1.0 1.5 1.9 1.3 1.5 0.9 1.5 1.3 1.8 -1.9 0.9 -1.4 1.1 0.9 1.8 1.5 0.7
Hair/balding pattern: Pattern 2 0.3 0.4 8.8 0.4 -0.1 0.3 -0.8 -3.0 0.1 0.0 0.0 -0.6 0.7 -0.0 0.0 -0.2 -0.0 0.2 -0.3 0.1 0.3 -0.0 0.0 -0.2 1.3 0.0 0.1 0.4 -0.1 -0.3 -0.1 0.1
Had menopause 8.0 9.9 20.2 -2.0 4.0 1.4 3.7 1.8 3.1 2.9 3.4 3.8 -0.8 3.2 3.3 2.7 3.2 3.3 2.7 3.2 3.8 3.7 3.5 3.1 -1.6 3.1 -3.4 3.2 1.8 3.6 4.1 4.5
Had other major operations 0.5 0.6 5.1 0.8 -0.4 0.4 0.3 0.6 -0.7 0.5 -0.1 -0.5 -2.3 -0.6 -0.4 -0.9 -0.6 -0.5 -1.3 -0.5 -0.4 -0.6 -0.7 -0.4 1.3 -0.6 0.9 -0.0 -0.5 -0.4 -0.3 -0.3
Forced vital capacity (FVC) 0.9 3.5 8.0 1.8 -1.9 -2.1 -2.8 -1.8 -2.0 -1.7 -2.1 -2.2 -0.2 -1.9 -1.8 -1.8 -2.0 -2.2 -0.4 -1.8 -1.5 -2.4 -2.1 -1.9 1.1 -1.2 2.6 -2.1 -1.2 -2.2 -1.7 -1.7
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.6 3.6 -0.2 -0.5 -1.2 -0.9 -0.6 -0.7 -0.6 -1.2 -0.7 1.0 -0.9 -0.7 -0.7 -0.8 -0.6 0.1 -0.7 -0.4 -0.7 -0.5 -0.1 -0.7 -0.8 0.4 -1.9 -0.7 -0.6 -0.0 -0.9
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.6 0.3 0.4 0.5 0.3 -1.2 0.7 0.4 0.9 0.9 -1.3 0.8 0.4 0.4 0.8 0.8 0.3 0.7 0.4 0.9 0.7 0.5 0.6 0.6 -1.2 0.0 0.1 0.9 0.3 0.3
Qualifications: None of the above 0.6 1.3 3.8 -0.7 1.2 1.9 -0.3 1.1 1.0 1.1 1.1 1.0 -0.4 1.1 0.9 1.0 1.1 0.9 1.9 0.9 1.4 1.0 1.0 1.1 -1.8 1.3 -1.1 1.7 0.7 1.3 0.4 0.5
Financial difficulties in last 2 years 5.3 7.2 11.4 1.1 -3.0 -2.0 -2.6 -1.3 -3.0 -2.7 -2.6 -2.7 -2.1 -2.9 -3.1 -3.0 -2.9 -3.0 -3.3 -2.9 -2.7 -2.9 -3.0 -2.6 1.8 -2.7 2.5 -3.4 -2.8 -2.2 -2.5 -2.8
Mouth/teeth dental problems 2.3 3.5 7.1 1.9 -1.9 -2.1 -2.0 -2.7 -1.9 -1.7 -2.3 -2.4 0.5 -1.9 -2.0 -1.5 -2.0 -1.8 -1.5 -1.8 -1.8 -1.8 -1.8 -1.7 2.2 -2.0 1.8 -2.2 -1.1 -2.5 -1.3 -1.2
Heart attack 0.5 0.6 5.7 -0.7 0.5 2.4 -0.9 -1.3 0.7 1.1 1.0 0.2 -0.2 0.7 0.9 -0.1 0.8 0.4 1.0 0.7 0.9 0.5 0.5 0.3 -0.0 0.3 -0.5 0.7 0.6 0.2 -0.3 -0.2
Allergy 0.1 0.2 0.9 0.1 0.0 -0.1 -0.4 -0.4 0.4 0.6 0.2 0.0 -0.6 0.5 -0.1 0.6 0.5 -0.0 0.6 0.4 -0.2 0.1 0.3 -0.2 -0.3 -0.2 0.0 1.0 0.7 -0.1 -0.7 -0.4
Pain all over the body in last month 0.3 0.3 1.7 -1.3 0.0 0.8 -0.7 1.0 0.2 -0.9 0.4 0.3 -1.2 0.2 0.5 0.2 0.2 0.1 0.3 0.1 0.3 -0.1 0.1 -0.1 -0.3 0.2 -0.6 -0.2 -0.2 0.3 -0.3 -0.3
Diabetes (self-reported) 2.0 3.1 7.3 1.8 -2.4 -1.1 -1.0 -1.2 -1.9 -1.9 -2.0 -1.5 -0.4 -1.9 -1.9 -1.8 -1.8 -1.7 -2.5 -1.9 -1.8 -1.8 -2.0 -1.7 0.5 -2.1 1.6 -2.7 -0.8 -1.7 -1.4 -2.1
Hayfever/allergic rhinitis (self-reported) 0.1 0.2 1.1 -0.6 0.2 0.7 1.1 0.3 0.1 0.1 0.1 0.3 1.0 0.1 0.3 -0.0 0.1 0.4 -0.5 -0.0 0.1 0.1 0.0 0.4 0.7 0.5 0.0 0.2 -0.1 0.0 0.2 0.3
Medication: Ramipril 0.2 0.3 2.7 0.6 -0.0 1.1 -0.0 -1.6 0.5 0.4 0.3 0.1 0.8 0.3 0.1 0.2 0.4 0.5 0.1 0.3 0.5 0.5 0.4 0.4 0.6 -0.3 0.1 0.4 0.7 0.5 -0.0 -0.5
Medication: Simvastatin 1.6 2.4 5.5 0.4 1.4 1.5 2.1 1.6 1.5 1.1 1.1 1.5 0.9 1.4 1.8 1.3 1.4 1.6 1.3 1.5 2.2 1.8 1.6 1.7 -0.7 1.3 -1.5 1.4 2.1 1.0 2.4 1.7
Fluid intelligence score 0.6 1.3 4.1 0.1 -0.9 -1.3 -0.4 0.2 -1.0 -1.8 -0.8 -1.1 -2.0 -0.9 -0.9 -1.3 -0.9 -1.6 -1.5 -0.8 -1.0 -0.9 -1.0 -0.9 1.7 -1.2 0.9 -1.4 -1.5 -1.2 -1.0 -0.9
Illnesses of siblings 0.6 0.9 3.1 -0.6 -0.9 -1.2 -0.2 -0.3 -0.8 -1.8 -1.1 -1.2 -0.1 -0.9 -0.9 -0.7 -0.9 -1.0 -0.6 -0.8 -1.0 -0.8 -0.8 -0.7 1.0 -1.0 1.1 -1.1 -1.4 -0.8 -0.9 -1.0
Neuroticism score 1.7 3.6 6.8 -0.8 1.7 0.5 1.5 1.2 2.4 2.2 2.6 2.3 1.3 2.4 2.0 2.1 2.4 2.4 1.2 2.4 1.3 2.2 2.2 1.8 0.2 2.1 -2.0 1.5 1.6 2.3 1.6 1.5
Weight 3.9 19.1 33.3 3.2 -5.4 -2.6 -4.5 -2.9 -4.7 -5.4 -5.5 -5.2 -1.9 -4.8 -4.2 -4.4 -4.7 -4.6 -4.1 -4.4 -3.8 -4.9 -4.8 -3.7 1.9 -5.1 4.2 -5.8 -2.2 -4.6 -3.7 -5.5
Impedance of arm (right) 1.9 8.9 22.9 -3.1 3.1 2.6 1.2 1.4 3.5 3.7 4.1 3.2 0.7 3.5 3.3 3.0 3.4 2.9 3.6 3.2 2.7 3.1 3.1 2.5 -1.4 3.5 -2.4 4.8 2.0 3.2 1.3 2.6
Arm fat percentage (right) 3.4 13.2 24.0 2.5 -4.6 -1.6 -3.9 -3.0 -3.7 -4.6 -4.5 -4.4 -1.6 -3.8 -3.3 -3.5 -3.7 -3.9 -3.9 -3.5 -3.1 -4.0 -3.9 -3.0 2.1 -4.7 3.3 -4.6 -1.7 -3.5 -3.3 -4.9
Trunk fat-free mass 2.4 13.8 27.0 2.5 -4.2 -2.8 -2.8 -2.6 -4.2 -4.9 -4.7 -4.5 -1.1 -4.2 -3.8 -3.8 -4.2 -3.9 -3.4 -3.8 -3.1 -4.2 -4.1 -3.3 1.5 -4.0 3.6 -5.2 -2.6 -4.0 -3.0 -4.2
Hip circumference 4.1 17.6 31.4 2.7 -5.0 -2.8 -4.2 -3.3 -4.5 -5.5 -5.4 -5.0 -1.6 -4.6 -4.2 -4.2 -4.5 -4.5 -4.0 -4.3 -3.6 -4.6 -4.5 -3.4 1.7 -5.0 3.8 -5.6 -2.4 -4.4 -3.3 -5.0
Time employed in main current job 0.2 0.3 1.7 -0.5 -0.0 -0.1 0.0 0.2 -0.3 -0.3 -0.9 -0.3 1.2 -0.3 -0.5 -0.0 -0.3 0.2 1.3 -0.3 -0.3 -0.0 -0.1 0.3 -1.3 0.1 0.2 -0.7 0.1 -0.4 0.6 -0.0
Alcohol intake versus 10 years previously 4.7 7.1 14.4 3.8 -2.4 -1.1 -2.9 -2.0 -3.0 -2.0 -2.4 -2.6 -1.7 -3.0 -3.0 -3.4 -3.1 -2.5 -3.1 -3.0 -2.8 -2.8 -2.9 -2.5 1.6 -2.7 2.7 -3.0 -2.4 -2.5 -2.4 -2.1
Father’s age at death 0.2 0.3 3.3 0.1 0.1 1.1 -0.1 -1.8 0.4 0.9 0.7 0.6 0.1 0.3 0.5 0.4 0.3 0.6 0.4 0.2 0.4 0.3 0.3 0.1 0.1 -0.0 -0.2 0.4 0.7 0.4 0.1 0.1
Worrier / anxious feelings 1.3 2.5 5.6 -0.5 1.4 0.6 1.6 2.4 1.5 2.1 2.1 2.2 1.9 1.6 1.8 1.3 1.5 1.6 1.4 1.6 0.8 1.5 1.5 1.2 0.4 2.1 -1.7 1.1 0.4 1.8 1.4 2.0
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.4 1.2 0.9 -0.8 0.9 -1.1 -0.7 -0.5 -0.3 -0.5 -0.3 -0.5 -0.6 -0.7 -0.6 -0.5 -0.2 -0.8 -0.7 -0.8 -0.5 -0.6 -0.6 -0.1 -0.9 0.6 -0.7 0.4 -0.5 -0.6 -1.1
Falls in the last year 0.4 0.6 4.7 2.1 -1.2 2.2 -0.9 -0.4 -0.2 -0.4 -0.3 -0.5 -0.1 -0.3 -0.0 -0.4 -0.2 0.1 0.0 -0.1 -0.6 -0.3 -0.2 -0.5 -1.0 -0.9 -0.3 -0.5 1.3 -0.4 -0.2 -0.8
Hair/balding pattern: Pattern 3 3.0 4.5 8.0 0.6 -2.3 -0.5 -1.9 0.1 -2.5 -1.8 -2.3 -2.2 -0.5 -2.5 -2.1 -2.5 -2.4 -2.6 -2.8 -2.5 -2.7 -2.4 -2.5 -2.4 0.5 -2.2 2.4 -1.8 -1.3 -2.4 -2.0 -2.2
Number of live births 0.4 0.6 2.1 0.3 -0.8 1.4 -0.4 -0.4 -0.7 -1.1 -0.9 -0.4 -0.1 -0.8 -1.0 -1.0 -0.7 -0.5 0.0 -0.9 -0.6 -0.7 -0.8 -0.9 -1.5 -1.0 0.5 -0.1 0.0 -0.2 -1.0 -1.4
Forced expiratory volume in 1-second (FEV1) 1.1 3.8 8.6 1.7 -2.0 -2.3 -2.9 -2.0 -2.0 -2.1 -2.3 -2.4 -0.3 -1.9 -1.7 -1.7 -2.0 -2.3 -0.4 -1.7 -1.6 -2.4 -2.1 -1.8 1.3 -1.5 2.5 -2.2 -1.1 -2.1 -1.7 -1.8
Pulse rate 0.6 1.1 5.2 0.3 0.7 1.4 1.2 1.3 0.9 1.4 1.4 1.1 2.3 1.0 0.6 1.1 1.0 1.3 0.4 0.8 0.5 1.0 1.0 0.9 0.1 1.3 -0.7 -0.1 0.1 1.6 0.5 0.5
Happiness 4.3 5.2 8.8 -0.7 2.7 0.5 2.4 1.1 2.5 2.5 2.6 2.2 0.5 2.6 2.8 2.1 2.5 2.1 1.6 2.7 2.9 2.7 2.6 2.5 -0.9 2.6 -2.6 2.1 1.3 2.6 2.6 3.0
Noisy workplace 0.9 1.1 2.7 1.1 -1.2 1.2 -1.4 -1.6 -1.0 -0.8 -1.0 -1.4 -0.7 -1.0 -0.6 -1.1 -0.9 -1.0 -0.8 -0.9 -0.5 -1.1 -1.0 -0.9 -1.0 -1.2 1.0 -0.4 0.1 -1.1 -1.1 -1.5
Qualifications: A levels/AS levels or equivalent 0.5 1.1 3.9 1.7 -1.6 -2.0 -0.6 -0.4 -0.8 -1.3 -1.2 -0.7 -0.9 -0.8 -1.0 -0.6 -0.8 -0.7 -1.4 -0.9 -1.1 -1.0 -0.9 -0.9 0.1 -0.7 1.0 -1.3 0.2 -1.4 -0.7 -1.0
Serious illness, injury or assault of a close relative in last 2 years 1.4 1.6 4.8 0.2 -1.3 -0.9 -1.9 -1.2 -1.1 -1.5 -1.6 -2.0 -0.6 -1.1 -0.4 -1.1 -1.1 -1.6 -0.5 -1.0 -0.6 -1.4 -1.2 -1.3 0.4 -1.4 1.4 -1.0 -0.3 -2.2 -1.2 -1.6
Mouth/teeth dental problems: Dentures 3.3 5.6 9.5 -0.4 2.1 2.2 1.5 2.4 2.6 1.9 2.5 2.6 0.5 2.7 2.9 2.3 2.7 2.5 2.4 2.7 2.9 2.3 2.5 2.5 -3.1 2.5 -1.9 2.7 2.8 2.4 1.9 1.3
Asthma 0.2 0.4 2.6 1.2 -0.3 0.8 -0.5 -0.8 -0.6 0.4 -0.2 -0.2 0.4 -0.7 -0.4 -1.1 -0.6 -0.1 -1.6 -0.6 -0.6 -0.5 -0.5 -0.6 0.6 -0.2 0.4 -0.9 -0.6 -0.4 -0.0 -0.0
Medication: Ibuprofen (e.g. Nurofen) 3.3 4.2 8.0 2.0 -2.2 -0.6 -2.5 -2.4 -1.9 -2.0 -1.8 -2.2 -1.4 -1.7 -2.1 -1.6 -1.7 -2.3 -2.0 -1.8 -1.8 -2.4 -2.1 -2.1 0.8 -2.5 2.4 -2.4 -1.4 -2.0 -2.6 -2.8
Medication: Cholesterol lowering 1.6 2.5 4.5 0.4 1.2 1.9 1.2 0.7 1.8 1.5 1.6 1.7 -0.0 1.7 2.1 1.7 1.7 1.8 1.6 1.8 2.0 1.9 1.8 1.7 -0.6 1.1 -1.7 1.8 2.1 1.4 1.5 1.2
Depression (self-reported) 0.6 0.7 5.2 -2.3 1.0 -0.5 1.0 1.5 0.3 1.0 1.0 1.1 0.6 0.4 -0.1 0.5 0.4 0.3 -0.3 0.2 -0.6 0.7 0.3 0.6 1.2 0.3 -0.2 0.4 -1.2 0.6 0.4 0.6
Medication: Lansoprazole 0.5 0.5 2.7 1.3 -0.9 -1.0 -1.2 -1.7 -0.6 -0.7 -0.8 -0.6 0.3 -0.5 -0.2 -0.7 -0.5 -0.4 -0.6 -0.4 -0.2 -0.6 -0.5 -0.5 0.8 -0.6 0.2 -0.7 0.3 -1.0 -0.2 -0.2
Prospective memory result 8.4 10.3 14.4 -1.8 3.4 1.7 3.4 2.8 3.4 3.8 3.4 3.7 0.5 3.4 3.4 3.5 3.4 3.6 3.2 3.3 3.2 3.6 3.6 3.2 -2.6 3.5 -3.4 2.5 2.7 3.5 3.8 3.7
Lung cancer (father) 1.4 1.7 3.1 0.5 -1.4 -0.8 -1.4 -0.0 -1.4 0.5 -1.1 -1.2 -1.5 -1.4 -1.3 -1.5 -1.4 -1.7 -0.3 -1.5 -1.3 -1.4 -1.5 -1.8 1.3 -1.4 1.8 -1.3 -1.1 -1.7 -1.2 -1.1
Illnesses of mother 0.6 0.7 4.0 -1.4 -0.4 -0.4 1.2 0.4 -0.8 -1.0 -0.5 -0.3 0.1 -0.9 -1.5 -0.4 -0.9 -0.7 -1.1 -1.1 -1.1 -0.3 -0.8 -0.3 0.7 -0.5 0.5 -0.8 -2.0 0.1 -0.6 -0.5
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.4 6.2 1.1 -1.0 -2.5 -1.1 -0.1 -1.2 -1.4 -1.5 -1.4 0.3 -1.1 -1.1 -0.9 -1.2 -1.5 0.1 -1.0 -1.0 -1.4 -1.2 -0.8 1.3 -0.4 1.4 -1.6 -1.2 -1.1 -0.6 -0.3
Pulse wave Arterial Stiffness index 0.4 0.5 2.0 1.0 -0.8 0.1 -0.8 -1.3 -0.5 -0.1 -0.1 -0.5 -0.7 -0.5 -0.7 -0.6 -0.5 -0.5 -0.5 -0.7 -0.2 -0.8 -0.7 -0.9 -0.0 -0.6 0.7 -0.6 -0.5 -1.0 -1.4 -1.2
Impedance of arm (left) 2.2 10.3 24.6 -2.8 3.2 2.4 1.4 1.6 3.8 4.0 4.2 3.3 0.3 3.8 3.9 3.2 3.7 3.2 4.0 3.6 3.1 3.3 3.4 2.8 -1.9 3.7 -2.8 5.0 2.9 3.2 1.8 2.9
Arm fat mass (right) 4.4 18.1 33.3 3.0 -5.2 -2.1 -4.3 -3.1 -4.5 -5.3 -5.2 -5.0 -2.0 -4.5 -4.0 -4.2 -4.5 -4.5 -4.4 -4.2 -3.5 -4.7 -4.5 -3.6 2.1 -5.3 3.9 -5.8 -2.4 -4.1 -3.8 -5.6
Trunk predicted mass 2.2 12.6 25.9 2.4 -4.0 -2.7 -2.6 -2.5 -4.0 -4.8 -4.5 -4.3 -1.2 -4.0 -3.6 -3.6 -4.0 -3.8 -3.2 -3.6 -2.9 -4.0 -3.9 -3.1 1.4 -3.8 3.5 -5.1 -2.5 -3.8 -2.8 -4.1
Standing height 0.1 1.1 2.6 0.3 -1.4 -0.8 -1.6 -0.8 -1.1 -1.1 -0.9 -1.5 -1.0 -1.0 -0.6 -1.1 -1.1 -1.1 0.6 -0.8 -0.2 -1.4 -1.2 -1.1 -0.5 -0.2 1.6 -1.1 -0.5 -1.1 -1.4 -1.4
Length of working week for main job 1.3 1.4 3.2 0.9 -1.3 -0.6 -1.7 -0.1 -1.2 -0.5 -1.1 -1.0 -0.2 -1.3 -1.2 -1.4 -1.2 -1.1 -0.8 -1.2 -1.4 -1.4 -1.4 -1.1 0.8 -1.4 1.6 -1.7 -0.6 -1.4 -1.4 -1.8
Exposure to tobacco smoke at home 0.3 0.4 1.6 1.3 -0.8 0.5 -1.0 -1.1 -0.2 -0.1 -0.1 -0.2 0.3 -0.3 -0.4 -0.2 -0.3 -0.3 -0.3 -0.4 -0.1 -0.7 -0.4 -0.9 -0.1 -0.6 0.7 -0.2 0.8 -0.5 -0.8 -1.0
Breastfed as a baby 0.3 0.4 3.1 1.7 -0.8 0.7 -0.7 -1.7 -0.4 -0.2 -0.4 -0.4 0.6 -0.3 0.2 -0.3 -0.3 -0.1 -0.1 -0.2 0.4 -0.5 -0.4 -0.6 -0.1 -0.4 0.2 -0.3 0.8 -0.7 -0.3 -0.5
Tense / ‘highly strung’ 8.7 14.5 22.8 -1.9 3.8 1.4 3.2 2.5 4.5 4.1 4.8 4.4 0.8 4.5 4.2 4.4 4.5 4.5 3.2 4.5 3.8 4.4 4.5 4.0 -1.6 4.4 -4.2 3.1 3.1 4.4 3.8 3.8
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 4.6 0.2 -0.0 -0.1 -1.4 -1.3 -0.2 -0.5 0.2 -0.4 -2.1 -0.1 -0.8 -0.2 -0.1 -0.5 -0.7 -0.2 -0.7 -0.2 -0.2 0.1 0.4 -0.2 0.1 -0.9 -1.0 0.6 -0.6 -0.8
Hair/balding pattern: Pattern 4 0.1 0.3 2.9 0.4 0.5 -0.8 1.0 1.7 0.1 0.9 0.3 0.6 -0.4 0.2 0.1 0.5 0.1 0.1 -0.3 0.2 0.4 0.1 0.3 0.1 -0.0 0.5 -0.2 0.2 0.2 0.4 0.8 1.3
Birth weight of first child 0.7 1.3 9.3 0.0 -0.6 -0.3 -0.5 -0.9 -1.0 -1.0 -0.8 -1.2 -3.1 -1.0 -0.8 -1.2 -1.0 -1.3 -1.5 -1.0 -0.7 -1.1 -1.0 -1.1 0.7 -1.3 0.7 -1.4 -1.0 -0.5 -0.9 -1.2
Peak expiratory flow (PEF) 2.9 6.7 11.2 1.5 -2.8 -1.3 -3.4 -1.5 -2.8 -2.0 -2.7 -2.9 -0.6 -2.7 -2.7 -2.7 -2.8 -2.9 -2.1 -2.6 -3.0 -3.3 -3.0 -2.6 1.9 -2.6 3.0 -2.9 -2.1 -2.7 -2.8 -3.0
Pulse wave reflection index 1.2 1.5 5.2 1.5 -1.0 -1.4 -1.2 -1.4 -1.2 -0.4 -1.1 -1.1 -2.3 -1.2 -1.3 -1.3 -1.2 -1.2 -1.1 -1.3 -0.6 -1.1 -1.2 -1.1 1.7 -1.1 1.1 -1.0 -0.9 -1.7 -0.9 -0.7
Ever highly irritable/argumentative for 2 days 1.7 2.0 5.0 1.4 -1.6 -0.9 -1.6 -1.3 -1.6 -2.2 -1.8 -1.6 -1.8 -1.4 -1.4 -1.7 -1.3 -1.5 -0.6 -1.2 -1.0 -1.4 -1.5 -1.0 1.0 -1.1 1.2 -2.0 -0.6 -1.4 -0.9 -1.6
Loud music exposure frequency 0.4 0.4 2.8 0.5 0.4 0.7 -0.1 0.3 0.6 0.1 0.3 0.3 0.2 0.7 0.7 0.5 0.7 0.6 0.6 0.6 0.4 0.5 0.6 0.4 -1.0 0.4 -1.1 0.7 1.7 0.1 0.6 0.6
Qualifications: O levels/GCSEs or equivalent 5.6 8.9 13.5 1.9 -3.2 -2.9 -2.8 -2.7 -2.9 -3.1 -3.0 -3.1 -1.3 -3.0 -3.2 -2.8 -3.1 -3.2 -3.6 -3.0 -3.7 -3.2 -3.1 -3.1 3.0 -3.1 3.1 -3.2 -2.4 -3.1 -2.9 -2.7
Mouth/teeth dental problems: Bleeding gums 0.8 1.1 4.0 -1.2 0.9 1.4 0.6 0.4 0.9 1.0 1.0 1.1 1.3 0.9 0.9 0.8 0.9 0.8 1.7 0.8 1.0 1.1 0.9 1.1 -2.0 1.2 -1.1 0.8 0.5 1.0 0.9 0.7
Blood clot in the leg (DVT) 0.4 0.6 4.0 -0.0 0.7 -2.0 0.5 0.9 -0.1 -0.9 -0.3 0.1 -1.6 -0.2 0.1 0.0 -0.2 -0.0 0.2 -0.1 0.7 0.4 0.3 0.5 0.2 0.6 -0.5 -1.1 -1.2 0.2 1.4 1.2
Medication: Paracetamol 3.5 5.7 11.8 2.5 -2.9 -1.5 -1.4 -1.6 -2.6 -2.9 -2.6 -2.5 -0.9 -2.6 -2.9 -2.5 -2.6 -2.4 -2.5 -2.4 -2.2 -2.6 -2.5 -2.3 0.2 -3.4 2.3 -3.4 -1.6 -1.9 -2.1 -2.7
Headache pain in last month 1.5 2.6 4.2 2.0 -1.5 -1.3 -2.0 -1.6 -1.5 -1.9 -1.8 -2.0 -2.0 -1.6 -1.6 -1.7 -1.5 -1.9 -1.3 -1.5 -1.0 -1.7 -1.5 -1.4 -0.4 -1.9 1.4 -1.7 -0.3 -1.8 -1.2 -1.9
Medication for cholesterol, blood pressure or diabetes 1.9 3.1 4.9 0.0 -1.5 -2.1 -1.2 -0.6 -2.1 -2.1 -1.8 -1.8 -0.5 -2.1 -2.0 -2.1 -2.1 -2.1 -1.6 -2.1 -2.0 -2.1 -2.1 -2.0 0.4 -1.5 1.9 -2.2 -2.0 -1.7 -1.4 -1.3
Glaucoma (self-reported) 0.2 0.2 1.7 0.2 0.2 -1.2 0.2 0.3 0.1 -0.1 -0.4 0.3 1.3 0.2 0.2 0.4 0.2 0.0 0.3 0.1 0.8 -0.1 0.1 0.2 -0.5 0.3 0.0 0.2 0.5 -0.4 0.2 -0.1
Gout (self-reported) 0.8 1.0 5.6 2.4 -1.1 -0.4 -0.9 -1.3 -1.2 -1.0 -1.0 -0.9 -0.4 -1.1 -1.0 -0.8 -1.1 -1.0 -0.9 -1.2 -0.3 -1.1 -1.0 -1.2 -0.1 -0.4 0.6 -1.5 -0.8 -0.8 -0.9 -0.6
Hypothyroidism/myxoedema (self-reported) 0.6 1.3 7.9 1.2 -0.3 -0.9 -0.8 -0.2 -1.1 -1.3 -1.0 -1.2 -1.7 -1.0 -0.8 -1.1 -1.1 -1.3 -1.9 -1.0 -0.7 -0.8 -0.9 -0.9 2.8 -0.6 1.2 0.2 -0.9 -1.3 -0.3 0.4
Medication: Amlodipine 2.9 4.1 8.5 -1.6 2.6 1.1 2.3 1.4 1.9 2.6 2.0 2.4 0.1 1.8 1.7 1.8 1.8 2.1 2.2 1.8 2.0 2.3 2.2 2.1 -2.2 2.1 -2.7 0.7 0.7 2.2 2.9 2.5
Medication: Ventolin 100micrograms inhaler 1.1 1.5 9.5 -0.7 1.2 3.1 0.9 -0.1 1.0 1.6 1.6 1.5 0.8 0.9 1.0 0.4 0.9 1.3 1.6 0.8 1.2 1.2 1.0 1.0 -1.0 1.3 -1.3 0.5 -0.0 1.8 0.8 0.7
Birth weight 0.2 0.4 3.5 -0.5 -0.3 0.8 -0.2 -1.9 0.1 -0.9 -0.3 -1.1 -0.2 0.1 0.8 0.2 0.1 -0.2 0.1 0.6 0.0 -0.2 -0.1 0.2 1.1 -0.6 0.6 0.1 0.2 -0.2 -0.6 -1.0
Chronic bronchitis/emphysema (mother) 0.5 0.5 3.9 1.0 -0.6 0.2 -0.5 0.3 -0.8 -0.1 -0.4 -0.5 2.0 -0.7 -0.8 -1.0 -0.7 -0.5 -0.8 -0.6 -0.1 -0.9 -0.7 -0.9 -0.6 -0.8 0.7 -0.7 -0.6 -0.1 -0.7 -0.8
High blood pressure (siblings) 0.9 1.4 3.3 -0.1 1.3 0.0 0.7 0.4 1.1 1.8 1.4 1.5 -1.0 1.3 1.1 1.2 1.2 1.1 1.1 1.2 1.5 1.1 1.2 1.0 0.2 1.4 -1.2 1.6 1.1 1.0 1.0 1.6
Forced vital capacity (FVC), Best measure 0.3 1.1 5.6 1.2 -0.8 -2.4 -1.0 0.3 -1.1 -0.6 -1.2 -1.1 0.3 -1.0 -1.1 -0.9 -1.2 -1.3 0.3 -1.0 -0.9 -1.2 -1.1 -0.8 1.1 -0.0 1.4 -1.5 -1.4 -1.1 -0.6 -0.1
Body fat percentage 3.3 13.1 22.8 2.6 -4.6 -2.0 -4.3 -3.0 -3.7 -4.3 -4.5 -4.3 -2.4 -3.8 -3.2 -3.6 -3.7 -3.8 -3.7 -3.5 -2.9 -4.0 -3.9 -3.0 2.1 -4.5 3.5 -4.2 -1.3 -3.8 -3.2 -4.8
Leg fat percentage (right) 4.1 15.0 25.3 2.5 -4.6 -2.9 -4.1 -3.1 -4.2 -4.7 -5.0 -4.6 -1.9 -4.2 -3.6 -3.9 -4.1 -4.1 -4.4 -3.9 -3.4 -4.2 -4.2 -3.1 2.4 -4.7 3.7 -4.6 -1.8 -4.2 -2.9 -4.7
Arm fat-free mass (right) 3.3 16.9 31.6 3.4 -4.8 -3.1 -3.4 -2.9 -4.6 -5.3 -5.3 -4.9 -1.9 -4.6 -4.1 -4.1 -4.6 -4.3 -3.8 -4.2 -3.4 -4.6 -4.5 -3.7 1.9 -4.5 4.0 -5.6 -2.4 -4.5 -3.2 -4.7
Exposure to tobacco smoke outside home 1.1 1.4 3.3 0.9 -1.4 -0.0 -1.1 -1.5 -1.2 -0.8 -1.3 -1.3 -0.7 -1.3 -1.0 -1.1 -1.2 -1.3 -1.5 -1.1 -1.3 -1.4 -1.2 -0.9 -0.3 -1.7 1.2 -1.7 -0.1 -0.9 -0.8 -1.8
Comparative body size at age 10 0.1 0.2 0.6 -0.6 -0.5 -0.5 0.7 -0.1 -0.4 -0.7 -0.4 -0.5 -0.3 -0.3 -0.6 0.3 -0.2 -0.1 -0.4 -0.1 -0.6 -0.2 -0.4 -0.3 0.8 -0.7 0.2 0.0 -0.6 -0.4 -0.7 -0.5
Number of full brothers 1.1 1.4 4.7 -0.3 -1.1 2.2 -0.5 -0.4 -1.1 -1.2 -0.8 -1.2 -0.3 -1.1 -1.2 -1.0 -1.0 -1.4 -0.9 -1.2 -1.6 -1.1 -1.2 -1.5 -0.2 -1.7 1.0 -1.2 -0.8 -0.5 -1.6 -2.0
Worry too long after embarrassment 2.1 3.5 6.2 -1.7 2.2 1.3 2.2 0.9 2.1 1.7 2.5 2.3 0.6 2.0 2.0 1.5 2.1 2.2 0.9 2.0 1.9 2.4 2.2 1.7 -0.7 1.8 -2.0 2.1 1.1 2.4 2.0 2.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.8 1.1 2.9 -1.4 0.9 0.4 0.1 1.0 1.4 1.3 1.5 1.2 -0.7 1.4 0.6 1.7 1.4 1.0 0.8 1.2 -0.0 1.1 1.2 1.4 -0.3 1.1 -1.0 0.4 0.3 1.3 0.3 0.1
Wheeze or whistling in the chest in last year 0.2 0.4 2.1 1.0 -0.4 1.4 -1.0 -0.6 0.3 0.8 0.3 0.5 1.1 0.2 0.1 -0.1 0.3 0.9 -0.6 0.2 0.4 0.3 0.2 0.5 -0.4 0.4 -0.5 -0.2 1.2 0.4 0.3 -0.7
Number of children fathered 4.7 5.3 8.9 0.2 -2.6 -1.5 -2.2 -0.2 -2.5 -2.5 -2.9 -2.5 -1.4 -2.6 -2.6 -2.5 -2.5 -2.6 -1.9 -2.7 -2.7 -2.2 -2.5 -2.2 1.5 -2.7 2.2 -3.0 -2.1 -2.4 -2.0 -2.5
Reason for reducing amount of alcohol drunk: Health precaution 1.4 1.6 2.8 -0.2 1.2 -0.0 1.3 -0.3 1.6 0.8 1.4 1.3 -0.7 1.6 1.7 1.6 1.5 1.7 0.5 1.7 1.6 1.5 1.5 1.2 0.6 1.6 -1.3 1.1 1.1 1.1 1.3 1.5
Age at first live birth 0.2 0.4 3.7 -0.1 -0.7 -1.9 0.4 1.5 -0.3 0.1 -0.4 -0.2 0.2 -0.3 -0.0 0.1 -0.4 -0.5 1.1 -0.2 0.1 -0.3 -0.2 -0.6 0.4 -0.1 0.5 -0.4 0.2 -0.7 0.3 0.7
Pulse wave peak to peak time 0.4 0.5 1.9 -1.0 0.6 -0.0 0.8 1.4 0.4 0.2 0.1 0.5 0.7 0.4 0.7 0.5 0.4 0.5 0.5 0.6 0.2 0.7 0.6 0.8 0.1 0.7 -0.7 0.6 0.5 0.9 1.3 1.1
Health satisfaction 3.5 4.5 8.1 -0.6 1.5 2.6 1.5 1.4 2.5 2.1 2.0 2.0 -0.4 2.5 2.1 2.5 2.5 2.4 2.0 2.4 2.0 2.5 2.5 2.6 -2.6 2.2 -2.4 1.8 2.8 1.7 2.2 1.2
Shortness of breath walking on level ground 0.2 0.2 1.1 0.1 -0.1 0.5 -0.1 0.3 -0.5 -0.4 -0.4 -0.3 -0.8 -0.4 -0.8 -0.5 -0.3 -0.1 -0.4 -0.5 -0.9 0.1 -0.3 0.1 -0.3 -0.4 -0.2 -1.1 -0.9 -0.3 0.3 -0.0
Qualifications: College or University degree 0.1 0.3 2.2 -0.7 -0.1 -0.1 1.5 0.1 0.1 -0.1 -0.5 -0.2 1.3 0.0 0.4 -0.1 0.0 0.0 0.5 0.1 -0.2 0.2 0.1 0.0 0.8 0.1 0.0 0.7 0.4 -0.7 0.6 0.6
Eye problems/disorders: None of the above 1.0 1.1 3.5 -0.4 -1.1 0.7 -1.1 -1.6 -0.8 -0.6 -0.4 -1.1 0.2 -0.8 -1.1 -1.1 -0.8 -1.1 -1.2 -1.0 -1.4 -1.0 -1.1 -1.3 1.2 -1.2 0.9 -0.5 -1.3 -0.7 -1.9 -1.4
Mouth/teeth dental problems: Loose teeth 0.5 0.6 2.9 -1.7 0.6 -0.1 1.0 1.3 0.6 0.1 0.9 0.8 0.2 0.7 0.3 1.0 0.6 0.6 0.4 0.6 -0.3 0.7 0.6 0.8 -0.8 0.7 -1.1 0.7 -0.4 1.1 0.3 0.7
Emphysema/chronic bronchitis 0.9 1.0 6.1 -0.1 -0.6 1.6 -0.9 -0.8 -1.0 -0.1 -0.3 -0.9 2.5 -1.0 -0.9 -1.5 -1.0 -0.6 -0.3 -0.9 -0.5 -0.7 -0.9 -0.5 0.5 -1.2 1.1 -0.7 -1.4 0.2 -1.0 -0.9
Medication for pain relief, constipation, heartburn 0.8 1.3 8.4 -2.9 1.5 -0.1 1.0 1.4 0.8 1.2 1.2 1.3 0.7 0.8 1.1 0.7 0.7 0.8 0.8 0.6 0.4 1.1 0.9 0.4 0.6 1.6 -1.5 1.3 -0.9 1.2 0.5 1.5
Neck or shoulder pain in last month 0.3 0.5 5.6 1.1 -0.5 -0.1 -0.9 -0.2 -0.2 -0.6 -0.6 -0.8 -2.4 -0.3 -0.3 -0.7 -0.2 -0.5 -0.5 -0.2 -0.3 -0.3 -0.2 -0.5 -0.6 -0.8 0.2 -0.4 0.8 -0.7 -0.2 -0.8
Medication: Blood pressure 1.7 3.1 6.0 0.3 1.7 2.0 1.4 0.1 2.0 2.5 2.1 2.0 0.0 2.0 1.9 1.9 2.0 2.1 1.3 2.0 2.1 2.1 2.0 1.8 -0.2 1.5 -2.0 1.8 1.6 1.9 1.4 1.6
Angina (self-reported) 0.8 1.1 4.0 -0.4 1.5 2.0 1.3 -0.1 1.0 0.7 1.4 1.4 0.4 1.0 1.0 0.7 1.0 1.2 1.0 1.0 1.2 1.2 1.0 0.7 -0.1 0.9 -1.2 0.6 0.2 1.3 1.1 1.3
Migraine (self-reported) 1.6 1.9 4.5 1.1 -1.2 -2.1 -1.6 -2.1 -1.3 -0.6 -1.2 -1.2 -1.2 -1.3 -1.4 -1.0 -1.4 -1.2 -1.9 -1.5 -1.6 -1.4 -1.3 -1.7 1.7 -1.1 1.7 -0.3 -0.8 -1.7 -1.4 -0.6
Medication: Ibuprofen 2.2 2.7 4.7 1.0 -1.7 -0.8 -1.2 -1.4 -1.7 -1.9 -1.5 -1.7 -0.7 -1.5 -1.8 -1.5 -1.5 -1.9 -2.2 -1.6 -1.6 -2.0 -1.8 -1.7 0.6 -2.1 1.9 -2.0 -1.6 -1.3 -2.0 -2.0
Medication: Allopurinol 0.4 0.5 5.9 2.4 -1.0 0.5 -0.4 -0.9 -0.6 -0.5 -0.6 -0.4 -0.3 -0.5 -0.3 -0.2 -0.5 -0.5 -0.4 -0.5 0.0 -0.8 -0.5 -1.1 -1.1 -0.1 0.3 -0.8 0.4 -0.5 -0.5 -0.2
Medication: Omeprazole 1.6 1.9 4.0 0.4 1.3 0.9 1.1 -0.4 1.4 1.8 1.5 1.5 1.5 1.5 1.4 1.3 1.5 1.8 0.4 1.5 1.5 1.5 1.5 1.6 -0.1 2.0 -1.0 0.8 1.4 1.6 1.7 1.7
Medication: Seretide 50 evohaler 0.4 0.5 2.4 -0.3 0.3 1.1 -0.3 0.2 -0.9 -0.7 -0.4 -0.6 -0.4 -0.9 -0.5 -1.6 -0.8 -0.9 0.1 -0.8 -0.4 -0.3 -0.7 -0.4 0.6 -0.9 0.1 -0.2 -1.5 0.0 -0.2 0.0
Mean time to correctly identify matches 0.4 0.7 5.0 0.8 -0.8 0.8 -1.7 -2.1 -0.2 -0.4 -0.4 -0.6 2.2 -0.1 0.4 -0.0 -0.1 0.3 -0.4 0.1 0.2 -0.6 -0.2 0.2 -1.4 -0.6 0.9 -0.2 0.9 -0.2 -0.4 -0.9
Heart disease (mother) 0.5 0.6 2.4 0.7 0.4 0.0 -0.9 -1.0 0.6 0.8 0.1 0.2 0.0 0.6 0.8 0.4 0.6 0.9 0.8 0.8 0.6 0.5 0.8 0.8 -1.4 0.7 -0.5 0.7 1.6 -0.0 1.2 0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.2 2.7 7.2 2.7 -1.8 -0.1 -2.4 -1.7 -1.5 -1.2 -1.6 -1.8 -0.0 -1.5 -1.7 -1.6 -1.5 -1.6 -1.2 -1.6 -1.6 -1.8 -1.7 -1.9 1.3 -1.3 1.6 -1.1 -0.2 -2.5 -1.9 -1.6
Whole body fat mass 4.4 18.2 30.2 3.2 -5.4 -2.3 -4.6 -3.0 -4.5 -5.1 -5.3 -5.0 -2.7 -4.6 -4.0 -4.3 -4.5 -4.5 -4.3 -4.3 -3.6 -4.8 -4.6 -3.7 2.2 -5.1 4.1 -5.3 -1.9 -4.4 -3.7 -5.5
Leg fat mass (right) 6.0 23.3 37.5 3.4 -5.9 -3.2 -4.8 -3.4 -5.2 -5.9 -6.1 -5.7 -2.2 -5.2 -4.7 -4.8 -5.2 -5.1 -5.1 -4.8 -4.4 -5.3 -5.2 -4.1 2.6 -5.7 4.7 -6.1 -2.4 -5.2 -4.0 -5.9
Arm predicted mass (right) 3.8 19.2 33.8 3.6 -5.1 -3.1 -3.7 -2.9 -4.8 -5.4 -5.4 -5.1 -2.3 -4.9 -4.4 -4.4 -4.8 -4.6 -4.3 -4.5 -3.7 -5.0 -4.8 -4.0 2.2 -4.8 4.4 -5.8 -2.7 -4.7 -3.7 -5.1
Pulse rate, automated reading 0.9 2.8 6.6 -0.3 1.5 1.5 2.2 1.0 1.8 2.1 2.4 2.3 1.2 1.7 1.3 1.7 1.7 2.3 0.3 1.5 1.0 1.9 1.8 1.5 0.2 2.6 -1.8 1.2 0.7 2.3 1.4 1.6
Alcohol intake frequency. 3.3 7.6 18.8 1.1 -2.8 0.8 -2.5 -1.2 -3.2 -1.9 -2.6 -2.7 -1.4 -3.3 -3.0 -3.5 -3.3 -2.8 -4.3 -3.5 -2.9 -3.2 -3.2 -2.7 0.3 -3.2 3.1 -2.3 -2.1 -2.4 -3.1 -3.0
Comparative height size at age 10 0.3 1.6 6.1 -1.0 -1.6 -0.9 -2.1 -1.0 -1.0 -1.3 -1.3 -1.9 -1.2 -1.1 -0.7 -1.1 -1.1 -1.6 -0.0 -1.0 -0.8 -1.4 -1.3 -1.0 -1.0 -0.8 1.2 -0.5 -0.4 -1.4 -1.9 -2.5
Number of full sisters 0.2 0.2 1.3 0.8 -0.2 0.9 0.6 0.3 -0.6 -0.4 -0.4 -0.1 1.2 -0.5 -0.2 -0.8 -0.5 -0.3 -0.0 -0.5 0.1 -0.4 -0.5 -0.7 0.1 -0.1 0.6 -0.3 -0.1 -0.4 -0.0 0.1
Suffer from ‘nerves’ 0.2 0.4 2.0 -1.4 0.6 1.1 0.4 0.3 0.4 1.0 1.0 0.6 0.7 0.4 0.5 0.2 0.5 0.2 1.0 0.3 -0.3 0.5 0.3 0.1 -0.1 0.3 -0.6 0.5 -0.0 0.5 -0.2 -0.4
Overall health rating 1.0 2.2 10.0 0.4 1.1 2.0 -0.1 -0.7 1.6 1.3 1.4 1.4 0.3 1.5 1.4 1.4 1.6 1.7 0.1 1.4 1.8 1.5 1.6 1.6 -3.2 1.2 -1.5 1.1 2.4 1.3 1.4 0.4
Chest pain or discomfort 0.1 0.2 1.2 -0.3 0.2 -0.3 -0.1 -0.8 0.0 -0.6 0.1 -0.3 -0.8 -0.1 0.1 -0.3 -0.0 0.1 0.2 0.1 -0.0 0.4 0.1 0.4 1.1 0.4 -0.1 -0.2 -0.9 0.0 0.4 0.3
Had major operations 1.1 1.3 3.0 -0.1 1.1 0.8 0.7 -0.7 1.1 0.7 0.6 0.5 0.8 1.0 1.2 0.9 1.1 1.5 1.5 1.3 1.7 1.5 1.4 1.5 -1.0 0.6 -1.6 0.7 0.9 1.1 1.7 1.1
Age at last live birth 0.4 0.6 2.9 -0.1 0.1 -1.2 0.4 0.9 0.6 0.4 0.3 0.3 -1.7 0.6 0.9 0.8 0.6 0.1 1.6 0.8 1.4 0.3 0.5 0.3 -0.8 -0.1 0.0 0.3 1.3 0.0 0.5 0.4
Family relationship satisfaction 2.4 2.9 6.4 -1.5 2.5 0.3 1.3 1.6 1.6 1.1 1.4 1.3 -1.2 1.7 2.0 1.4 1.7 1.3 1.4 1.8 2.5 2.1 1.9 2.5 -0.8 2.1 -2.0 1.5 0.6 1.2 2.5 2.2
Leg pain on walking 0.3 0.4 1.4 -0.9 0.6 1.1 0.3 0.5 0.6 -0.2 0.4 0.8 0.4 0.5 -0.1 0.5 0.6 1.0 0.4 0.4 -0.1 0.9 0.8 1.2 -0.5 0.1 -1.1 0.2 0.0 0.6 0.9 0.3
Qualifications: NVQ or HND or HNC or equivalent 1.9 2.3 5.5 0.7 -2.2 -0.7 -1.2 -0.9 -1.2 -1.4 -1.8 -1.5 1.4 -1.5 -1.6 -1.0 -1.4 -1.1 -1.8 -1.4 -1.9 -1.6 -1.5 -1.0 -0.0 -2.3 1.3 -2.3 -0.7 -1.2 -1.8 -2.4
Commuting to job workplace: Car/motor vehicle 3.6 4.2 7.6 1.0 -2.3 -1.6 -1.7 -1.4 -2.3 -2.2 -2.4 -2.0 0.4 -2.3 -2.5 -1.9 -2.3 -2.2 -1.6 -2.3 -2.5 -2.4 -2.3 -2.1 0.4 -2.8 2.2 -2.2 -1.4 -2.3 -1.8 -2.1
Illness, injury, bereavement, stress in last 2 years 7.8 9.6 16.1 -1.6 3.5 1.0 3.1 2.6 3.4 4.0 3.6 3.6 1.6 3.4 3.0 3.6 3.3 3.4 2.7 3.2 2.8 3.4 3.4 3.1 -1.1 3.7 -2.9 3.7 1.9 3.3 2.8 3.8
Medication: Aspirin 2.6 3.4 7.0 0.5 1.2 1.6 2.1 0.7 2.1 2.2 1.5 1.6 1.3 2.0 2.0 2.1 2.0 2.2 1.5 2.2 2.0 2.1 2.0 2.3 -1.1 1.5 -1.8 1.8 2.6 1.3 2.3 1.7
Supplements: Vitamin C 0.3 0.4 1.7 0.1 0.6 0.3 0.9 0.1 0.5 1.0 1.1 1.3 0.5 0.4 0.5 0.4 0.4 0.5 -0.2 0.3 0.8 0.4 0.5 0.2 -0.1 1.0 -0.3 0.6 0.2 0.9 0.3 0.8
Knee pain experienced in last month 0.5 0.8 2.3 0.6 0.9 -0.4 0.7 0.8 0.6 1.2 0.9 0.9 0.5 0.7 0.8 0.5 0.7 1.1 0.9 0.8 1.5 0.9 0.8 0.8 0.1 0.6 -1.2 -0.1 0.2 1.2 1.4 1.5
Hypertension (Self-reported) 0.9 2.5 4.1 0.0 1.4 1.0 1.3 1.0 1.8 1.5 1.3 1.6 0.9 1.9 1.8 1.9 1.9 1.9 1.1 2.0 1.5 1.8 1.8 2.0 0.5 1.6 -2.0 1.8 1.9 1.1 1.9 1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.2 1.3 5.1 0.6 0.7 -0.3 -0.2 0.2 1.2 1.0 0.7 1.1 1.4 1.2 1.2 0.9 1.3 1.6 0.5 1.2 0.9 1.1 1.3 1.3 -1.2 1.8 -0.9 1.0 2.3 0.6 1.7 1.3
Illnesses of father: Heart disease 1.2 1.6 5.3 -0.5 0.7 2.3 1.4 1.0 1.2 1.4 1.0 1.6 1.9 0.9 1.2 0.9 1.0 1.7 0.4 0.9 1.0 1.2 1.2 1.5 -1.1 0.7 -0.9 1.5 1.8 1.4 1.4 0.8
Illnesses of siblings: Diabetes 1.1 1.3 3.4 0.8 1.1 0.2 1.1 1.9 1.0 1.2 1.1 1.7 -0.6 1.2 0.9 1.1 1.2 1.2 0.4 1.1 0.8 1.2 1.2 0.9 -0.7 1.8 -1.5 0.8 1.3 1.0 1.4 1.5
Smoking status: Previous 1.9 2.8 16.9 4.1 -1.6 -2.1 -1.3 -0.9 -1.5 -1.1 -1.7 -1.8 -2.4 -1.4 -1.6 -1.2 -1.5 -1.7 -0.7 -1.0 -0.6 -1.6 -1.5 -1.6 1.7 -1.3 1.8 -2.5 -0.6 -1.8 -0.7 -0.9
Forced expiratory volume in 1-second (FEV1), predicted 0.4 0.7 4.2 -0.5 -1.2 -1.0 -2.1 -0.8 -0.5 -0.6 -0.7 -1.2 -0.1 -0.5 -0.9 -0.3 -0.6 -0.8 0.1 -0.5 -0.8 -1.0 -0.8 -0.6 -0.2 -0.3 1.2 -0.7 -0.5 -0.6 -1.4 -1.1
Whole body fat-free mass 2.8 16.0 31.9 3.0 -4.6 -3.0 -3.2 -2.7 -4.4 -5.3 -5.0 -4.8 -1.7 -4.4 -4.0 -4.0 -4.4 -4.3 -3.7 -4.0 -3.4 -4.5 -4.4 -3.6 1.9 -4.4 3.8 -5.7 -2.6 -4.2 -3.3 -4.6
Leg fat-free mass (right) 2.9 15.7 31.9 3.1 -4.7 -2.9 -3.3 -2.4 -4.3 -5.2 -4.8 -4.7 -1.8 -4.2 -4.1 -3.8 -4.2 -4.3 -3.5 -4.0 -3.5 -4.4 -4.3 -3.6 2.2 -4.4 3.8 -5.7 -2.7 -4.1 -3.5 -4.7
Arm fat percentage (left) 3.2 12.9 24.0 2.6 -4.6 -1.6 -4.0 -2.9 -3.7 -4.5 -4.5 -4.4 -1.8 -3.7 -3.1 -3.5 -3.6 -3.8 -3.9 -3.4 -3.1 -4.0 -3.8 -2.9 2.0 -4.7 3.2 -4.5 -1.4 -3.6 -3.2 -4.9
Average weekly red wine intake 0.3 0.4 5.4 0.4 -1.4 0.5 0.2 -1.0 0.2 -0.3 -0.6 -0.3 0.8 0.1 0.8 0.3 0.1 0.5 -0.1 0.4 -0.3 -0.2 0.1 0.1 -0.5 -0.2 -0.0 0.2 2.3 -0.6 0.2 -0.8
Handedness (chirality/laterality): Left-handed 0.3 0.4 6.0 -0.2 -0.1 2.4 -0.3 -0.1 0.2 0.3 0.3 0.2 0.2 0.2 -0.0 -0.0 0.3 0.0 0.6 -0.1 0.3 0.2 0.1 -0.3 -0.6 0.5 -0.5 1.0 0.6 -0.1 -0.7 -0.7
Mood swings 0.2 0.3 1.4 1.0 -0.8 -0.3 0.4 -0.8 0.0 1.0 0.2 0.1 0.7 -0.0 -0.6 -0.0 0.0 0.3 -0.9 -0.0 -0.7 -0.1 -0.1 -0.2 1.2 -0.3 0.0 -1.1 0.3 -0.0 -0.1 -0.7
Loneliness, isolation 0.1 0.1 0.4 -0.5 0.5 -0.1 0.0 0.6 0.3 0.3 0.7 0.5 -0.5 0.4 -0.1 0.3 0.4 0.3 0.5 0.3 0.4 0.4 0.3 0.3 0.1 -0.1 -0.3 0.5 -0.0 0.6 0.1 0.2
Long-standing illness, disability or infirmity 0.2 0.3 1.7 1.3 0.1 1.1 -0.3 0.1 0.3 0.4 0.0 0.1 0.3 0.2 0.3 0.0 0.3 0.6 -0.1 0.4 0.4 0.4 0.4 0.6 -1.3 -0.3 -0.3 -0.3 1.1 0.1 0.7 -0.4
Ever had bowel cancer screening 3.7 4.3 7.8 -0.5 2.0 2.0 1.9 1.0 2.2 1.6 1.8 2.1 -0.0 2.2 1.9 2.3 2.2 2.4 2.4 2.2 1.8 2.3 2.4 2.1 -2.6 2.0 -2.5 2.1 2.8 2.1 2.5 2.0
Diabetes diagnosed by doctor 1.0 1.7 4.5 1.6 -1.9 -1.2 -0.6 -0.4 -1.2 -1.6 -1.6 -1.0 -0.3 -1.2 -1.3 -1.1 -1.2 -1.0 -1.9 -1.3 -1.1 -1.3 -1.3 -1.0 0.2 -1.7 1.2 -2.1 -0.1 -1.4 -0.9 -1.8
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 2.8 -1.2 0.4 1.1 0.6 1.0 0.6 0.5 0.5 0.4 1.2 0.4 0.1 0.6 0.5 0.3 0.2 0.5 0.3 0.2 0.3 0.7 -1.7 0.3 0.4 1.4 0.6 0.3 -0.2 -0.8
Friendships satisfaction 0.8 1.1 2.7 0.3 1.3 0.7 0.3 1.3 1.1 1.2 1.3 1.0 -1.6 1.2 1.1 0.9 1.2 0.8 -0.3 1.2 1.5 1.0 1.1 1.2 -0.9 1.0 -0.8 0.8 0.5 1.2 0.8 0.7
Qualifications: nursing, teaching 0.5 0.7 2.5 1.6 -1.2 0.5 -1.4 0.4 -0.7 -0.2 -0.6 -0.8 -0.1 -0.8 -0.4 -0.8 -0.8 -0.6 -0.1 -0.8 -0.4 -1.0 -0.9 -1.1 0.4 -1.1 1.1 -0.5 0.3 -1.3 -1.0 -1.0
Commuting to job workplace: Walk 5.2 5.6 9.0 -0.9 2.4 2.2 2.2 2.6 2.5 2.1 2.8 2.5 -0.7 2.5 2.8 2.2 2.5 2.3 2.5 2.4 3.0 2.6 2.5 1.8 -1.8 2.6 -2.7 2.8 2.3 2.4 1.9 2.6
Eye problems/disorders: Cataract 1.6 1.9 4.7 -0.4 1.3 0.5 1.6 1.2 0.9 0.9 1.0 1.7 -0.9 1.0 1.5 0.9 1.0 1.6 1.4 1.1 2.1 1.4 1.4 1.2 -1.6 1.5 -1.6 0.9 1.5 1.3 2.2 2.1
Mouth/teeth dental problems: Mouth ulcers 0.2 0.3 2.2 -0.2 0.2 0.2 0.9 1.1 0.1 0.3 0.2 0.5 -1.5 0.2 0.4 -0.2 0.2 0.2 -1.1 0.1 0.4 0.1 0.2 0.1 -1.1 -0.3 -0.5 0.1 0.8 0.3 0.6 0.2
Medication for cholesterol 1.4 2.1 4.5 2.1 -1.4 -0.2 -2.0 -1.2 -1.6 -1.0 -1.2 -1.4 -0.8 -1.6 -1.9 -1.4 -1.6 -1.2 -0.7 -1.6 -1.3 -1.5 -1.6 -1.3 -0.5 -1.3 1.5 -1.9 -1.4 -1.0 -1.6 -1.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 1.3 -0.3 0.4 0.2 -0.3 -0.1 0.7 0.8 0.7 0.6 1.1 0.7 1.0 0.5 0.7 0.8 0.8 0.9 0.8 0.5 0.7 0.7 -1.1 0.5 -0.6 0.5 0.4 0.7 0.5 0.4
Back pain experienced in last month 1.1 1.6 5.0 2.2 -1.1 0.7 -1.2 -0.2 -1.4 -1.6 -1.6 -1.6 -0.9 -1.4 -1.8 -1.6 -1.2 -1.1 -0.3 -1.4 -1.3 -1.0 -1.1 -1.1 0.0 -1.5 0.6 -1.7 -0.7 -1.4 -0.4 -1.1
Mineral and other dietary supplements 0.3 0.3 1.9 -0.3 1.4 -0.1 0.9 -0.4 0.7 0.8 0.4 0.3 -0.3 0.5 0.6 0.6 0.5 0.2 0.2 0.5 0.5 0.8 0.7 0.9 -0.3 0.1 -0.4 0.9 -0.2 0.2 0.5 0.5
Breast cancer (self-reported) 1.1 1.3 3.1 1.4 -1.3 0.7 -0.8 -0.6 -1.5 -0.5 -1.4 -1.2 0.6 -1.5 -1.2 -1.8 -1.4 -1.1 -0.5 -1.4 -1.0 -1.2 -1.3 -1.0 -0.0 -1.1 1.4 -1.2 -0.5 -1.1 -0.6 -1.0
Asthma (self-reported) 0.1 0.3 2.2 1.2 -0.0 0.9 -0.2 -0.8 -0.4 0.4 -0.0 -0.0 0.5 -0.4 -0.1 -0.9 -0.4 0.1 -1.5 -0.4 -0.3 -0.2 -0.3 -0.3 0.4 -0.0 0.1 -0.8 -0.3 -0.2 0.2 0.1
Osteoporosis (self-reported) 4.5 5.6 9.4 -0.3 2.4 2.7 2.6 1.5 2.5 3.0 2.7 2.9 2.1 2.5 2.2 2.2 2.5 3.1 1.6 2.4 2.5 2.8 2.5 2.2 -1.6 1.9 -2.5 2.5 1.9 2.9 2.1 2.2
Osteoarthritis (self-reported) 0.3 0.4 2.7 -1.4 0.6 0.4 -0.1 -0.8 0.2 -0.7 -0.2 -0.4 1.4 0.2 0.3 0.1 0.3 0.3 -0.7 0.3 -0.2 0.4 0.3 0.8 -1.6 0.2 -1.0 0.9 -0.0 0.2 0.3 -0.1
Medication: Aspirin 2.4 3.2 6.9 0.6 1.2 1.6 1.7 0.5 2.1 2.1 1.5 1.5 1.4 2.0 2.1 2.1 2.0 2.2 1.4 2.2 2.0 2.0 2.0 2.3 -0.8 1.3 -1.8 1.7 2.6 1.2 2.1 1.5
Medication: Gliclazide 0.4 0.4 1.5 -0.3 -0.7 -1.2 -0.2 -0.7 -0.6 -0.9 -1.2 -0.8 -0.1 -0.6 -0.8 -0.4 -0.6 -0.6 -0.2 -0.6 -0.1 -0.5 -0.5 0.2 -0.9 -0.3 0.6 -0.9 0.0 -0.8 0.2 -0.8
Illnesses of father: None of the above (group 1) 1.0 1.2 4.3 -0.3 -0.7 -0.2 -1.4 -2.1 -0.9 -1.1 -0.4 -1.3 -1.1 -0.9 -0.8 -1.1 -1.0 -1.2 -0.3 -0.9 -1.2 -1.0 -1.1 -1.4 0.8 -1.1 1.0 -0.6 -2.0 -0.7 -1.8 -0.9
Smoking status: Current 0.1 0.2 2.0 -0.1 -0.3 -1.4 -0.2 -0.8 -0.2 -0.5 -0.4 -0.1 0.3 -0.3 -0.5 0.1 -0.3 -0.0 -0.6 -0.3 0.2 -0.0 -0.2 0.1 0.2 -0.1 0.4 -0.4 -0.6 0.1 -0.3 -0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.4 5.8 0.3 0.2 -0.8 0.2 -0.3 -0.1 -0.2 -0.8 -0.3 2.4 -0.0 -0.0 0.3 -0.1 0.1 0.4 0.0 -0.3 -0.1 0.1 0.7 -0.6 0.2 0.2 0.0 0.2 -0.2 1.0 0.7
Whole body water mass 2.6 15.0 31.1 2.8 -4.5 -2.9 -3.0 -2.6 -4.3 -5.2 -4.9 -4.7 -1.6 -4.3 -3.9 -3.8 -4.3 -4.2 -3.5 -3.9 -3.2 -4.3 -4.2 -3.4 1.7 -4.2 3.7 -5.6 -2.6 -4.0 -3.1 -4.5
Leg predicted mass (right) 2.9 15.7 32.3 3.1 -4.6 -2.9 -3.2 -2.4 -4.3 -5.3 -4.8 -4.7 -1.8 -4.3 -4.1 -3.8 -4.2 -4.2 -3.5 -4.0 -3.5 -4.4 -4.3 -3.6 2.3 -4.4 3.8 -5.7 -2.7 -4.0 -3.4 -4.7
Arm fat mass (left) 4.4 18.2 32.8 3.1 -5.3 -2.3 -4.4 -2.9 -4.5 -5.2 -5.3 -5.0 -2.2 -4.6 -4.0 -4.3 -4.5 -4.6 -4.5 -4.3 -3.6 -4.8 -4.6 -3.6 2.0 -5.3 4.0 -5.7 -2.3 -4.2 -3.8 -5.6
Number of self-reported non-cancer illnesses 0.3 0.6 2.2 0.4 0.9 -0.3 0.7 0.6 0.6 0.8 0.5 0.9 1.0 0.6 0.8 0.3 0.6 1.3 -0.1 0.7 0.7 0.9 0.8 1.1 0.5 0.8 -0.7 0.2 0.6 0.7 1.5 0.9
Average weekly champagne plus white wine intake 0.6 0.9 2.6 -0.3 1.2 1.3 0.2 -0.9 1.0 1.0 1.0 0.4 -0.4 1.1 1.3 0.8 1.0 0.3 1.5 1.1 1.1 0.9 1.0 0.8 -0.7 0.7 -0.6 1.6 0.9 0.4 0.6 0.9
Miserableness 0.2 0.3 2.4 0.7 -0.9 0.3 -0.7 -1.6 -0.2 0.3 -0.1 -0.3 -0.3 -0.2 -0.5 -0.4 -0.2 -0.1 -0.8 -0.2 -1.0 -0.4 -0.4 -0.3 0.1 -0.4 0.6 -0.3 0.6 -0.4 -0.4 -0.8
Guilty feelings 0.2 0.3 1.0 -0.4 0.7 -0.2 0.0 0.2 0.7 0.3 0.9 0.6 -0.9 0.7 0.0 0.6 0.7 0.4 0.1 0.6 -0.0 0.7 0.7 0.3 -0.3 0.8 -0.8 0.1 0.2 1.0 0.2 0.2
Wears glasses or contact lenses 0.4 0.5 4.0 0.7 -0.6 1.0 -0.9 -0.5 -0.2 -0.3 -0.4 -0.7 2.0 -0.1 -0.1 -0.2 -0.1 -0.2 1.0 -0.0 -0.4 -0.4 -0.4 0.2 -1.5 -0.4 0.8 0.0 0.6 -0.7 -0.5 -1.2
Ever taken oral contraceptive pill 3.5 3.9 8.1 1.6 -2.8 -1.2 -2.6 -2.0 -1.8 -1.8 -2.3 -2.0 0.3 -2.0 -1.9 -1.6 -2.0 -1.9 -0.5 -1.8 -1.8 -2.4 -2.1 -2.1 0.1 -2.5 2.7 -2.1 -0.1 -2.5 -2.0 -2.7
Hearing aid user 1.4 1.6 6.1 2.5 -1.5 -0.3 -0.9 -1.6 -1.4 -1.2 -1.3 -1.4 1.1 -1.3 -1.5 -1.0 -1.3 -1.2 -1.0 -1.2 -0.9 -1.5 -1.2 -1.2 -1.1 -0.9 0.9 -1.7 0.3 -1.5 -0.7 -1.3
Mother’s age at death 2.3 2.8 5.3 -1.0 1.8 1.1 2.1 0.2 1.9 0.8 1.7 1.4 1.4 1.9 1.8 1.9 1.9 1.7 2.3 2.1 2.0 1.8 1.9 1.8 -1.1 1.9 -1.7 1.6 1.2 1.8 1.7 1.8
Financial situation satisfaction 0.2 0.2 1.2 -0.2 0.2 0.2 -0.8 0.0 0.1 0.6 0.4 -0.4 -0.1 0.3 0.3 -0.0 0.3 -0.1 1.1 0.4 1.0 0.2 0.2 0.7 -0.8 0.4 -0.5 -0.5 0.1 0.2 0.3 -0.3
Tinnitus: Yes, now most or all of the time 0.1 0.2 1.1 0.0 0.2 1.1 -0.7 -0.8 0.1 0.5 0.4 0.6 0.9 0.2 0.0 0.0 0.1 0.4 -0.1 -0.0 -0.2 -0.1 -0.0 0.1 0.1 0.2 0.3 -0.0 0.2 0.1 -0.2 -0.5
Commuting to job workplace: Public transport 0.2 0.2 1.4 0.2 0.2 -0.3 -0.3 -0.9 -0.5 -0.0 -0.0 -0.4 0.1 -0.4 -0.4 -0.6 -0.4 -0.3 -0.8 -0.3 -0.1 -0.2 -0.5 -0.0 1.2 0.1 0.6 0.2 -1.0 -0.3 -0.6 -0.4
Eye problems/disorders: Glaucoma 0.5 0.6 1.3 -0.7 0.9 -1.2 0.2 0.5 0.8 0.6 0.2 0.6 0.8 0.8 0.9 1.0 0.8 0.4 0.8 0.7 1.0 0.6 0.8 1.0 -0.9 0.8 -0.4 0.8 0.9 0.1 0.8 0.6
Medication: Blood pressure 2.1 3.9 6.1 -1.6 2.0 0.7 1.8 1.1 2.3 1.8 1.9 2.2 1.0 2.3 2.4 2.2 2.3 2.1 2.0 2.3 2.0 2.2 2.3 2.3 -0.1 2.3 -2.0 2.5 2.2 1.3 2.1 2.1
Pain type(s) experienced in last month: Hip pain 0.7 0.9 2.5 1.6 -0.8 0.4 -0.4 -1.4 -1.0 -1.4 -1.4 -1.3 -0.4 -1.1 -0.8 -1.1 -1.0 -0.8 -0.9 -0.8 -1.1 -0.6 -0.8 -0.4 -0.5 -1.2 0.2 -1.4 0.0 -0.6 0.2 -0.8
Supplements: Fish oil (including cod liver oil) 0.1 0.1 0.8 0.8 -0.5 -0.5 -0.5 -0.1 -0.3 -0.1 0.1 -0.1 -0.9 0.1 -0.0 -0.2 -0.0 0.2 0.0 0.0 0.4 -0.3 -0.2 -0.6 0.6 0.0 0.2 -0.3 0.2 -0.1 -0.0 0.5
High cholesterol (Self-reported) 1.7 3.0 6.4 -1.0 1.7 0.6 2.2 1.7 1.8 1.3 1.3 2.1 -0.2 1.7 2.1 1.6 1.7 1.9 1.0 1.8 1.8 2.2 2.0 2.3 0.4 1.6 -1.7 2.0 1.5 1.8 2.5 2.2
Medication: Bendroflumethiazide 0.9 1.3 3.1 0.8 1.3 1.0 1.5 -0.2 1.2 1.7 1.2 1.5 0.5 1.1 1.5 0.8 1.1 1.3 0.3 1.1 1.2 1.3 1.2 1.0 0.8 0.8 -1.0 1.8 1.3 0.9 1.2 1.4
Medication: Paracetamol 2.7 4.2 11.5 1.5 -2.1 -1.3 -0.5 -1.3 -2.4 -2.6 -2.2 -2.1 -0.1 -2.4 -2.9 -2.1 -2.3 -2.0 -2.2 -2.3 -2.0 -2.1 -2.1 -1.7 -0.2 -2.8 1.7 -3.4 -2.3 -1.1 -1.6 -2.0
Medication: Lisinopril 7.4 9.6 16.4 -1.6 3.0 0.3 2.1 1.5 3.8 2.3 3.3 3.5 -0.2 3.9 3.6 4.1 3.9 3.7 3.4 3.9 3.0 3.7 3.7 3.6 0.0 3.5 -3.2 3.2 2.8 3.0 2.9 2.9
Medication: Atorvastatin 3.2 3.9 6.7 -0.8 2.1 1.1 1.2 -0.2 2.4 1.9 2.2 2.5 1.0 2.3 2.0 2.5 2.3 2.6 1.7 2.2 1.7 2.4 2.4 2.5 -0.6 1.8 -2.4 1.9 1.8 2.3 1.9 1.9
Illnesses of father: High blood pressure 3.6 4.4 7.8 -0.9 1.8 1.9 1.3 1.7 2.5 2.3 2.4 2.4 0.4 2.5 2.4 2.5 2.6 2.6 1.2 2.4 2.3 2.1 2.3 2.3 -1.6 1.6 -2.2 2.8 2.7 2.3 1.5 1.2
Alcohol drinker status: Never 0.3 0.4 1.4 -0.9 -0.7 0.3 -0.1 -0.5 -0.7 -0.1 -0.2 -0.6 0.5 -0.7 -0.8 -0.6 -0.7 -0.6 -1.2 -0.9 -1.0 -0.6 -0.8 -0.6 0.2 -0.6 0.6 0.0 -0.1 -0.5 -0.8 -0.7
Ever smoked 0.9 1.6 12.1 3.5 -1.1 -3.2 -0.6 -0.2 -0.9 -1.2 -1.5 -0.9 -1.3 -0.8 -1.2 -0.3 -0.9 -0.9 -0.7 -0.6 -0.5 -0.9 -0.8 -0.9 1.3 -0.5 1.1 -1.6 -0.0 -1.5 0.2 0.0
Basal metabolic rate 3.4 18.8 36.6 3.2 -5.0 -3.0 -3.7 -2.9 -4.8 -5.7 -5.3 -5.2 -1.9 -4.8 -4.4 -4.3 -4.7 -4.7 -4.0 -4.4 -3.7 -4.8 -4.7 -3.9 2.1 -4.8 4.2 -6.0 -2.9 -4.5 -3.6 -5.1
Leg fat percentage (left) 4.3 15.4 25.8 2.7 -4.8 -2.8 -4.1 -3.2 -4.2 -4.6 -5.1 -4.5 -1.8 -4.2 -3.7 -3.9 -4.2 -4.1 -4.6 -3.9 -3.5 -4.3 -4.2 -3.2 2.5 -4.8 3.7 -4.7 -1.8 -4.2 -3.1 -4.9
Arm fat-free mass (left) 3.3 16.9 33.8 2.9 -4.6 -3.1 -3.3 -2.6 -4.6 -5.3 -5.2 -4.8 -1.7 -4.6 -4.2 -4.1 -4.6 -4.4 -4.0 -4.3 -3.4 -4.6 -4.5 -3.6 1.9 -4.4 4.0 -5.8 -3.0 -4.2 -3.3 -4.8
Number of operations (self-reported) 1.2 1.8 5.8 -1.5 1.3 0.7 1.9 0.7 1.1 0.6 0.6 1.3 0.5 1.1 1.3 1.2 1.2 1.9 1.5 1.3 1.3 1.6 1.4 2.0 -0.6 1.0 -2.0 1.1 1.0 1.5 2.4 1.5
Average weekly beer plus cider intake 1.8 2.6 6.0 0.5 -1.3 -1.1 -1.0 -0.5 -1.8 -1.5 -1.4 -1.7 0.9 -1.8 -2.5 -1.7 -1.8 -1.9 -1.4 -1.9 -2.1 -1.5 -1.8 -1.6 1.4 -1.4 1.5 -2.0 -2.3 -1.3 -1.6 -1.5
Irritability 1.1 1.8 5.9 1.6 0.5 -2.0 -0.4 1.4 1.4 1.5 1.1 1.3 2.4 1.6 1.1 1.5 1.5 1.5 1.1 1.7 0.8 1.0 1.4 1.3 0.1 1.6 -0.5 -0.2 1.7 0.8 1.5 1.4
Risk taking 0.4 0.6 4.3 -0.9 0.2 -2.1 -0.2 0.2 -0.6 -1.1 -1.0 -0.8 -1.1 -0.5 -0.5 -0.5 -0.5 -1.1 -0.5 -0.4 -0.2 -0.3 -0.5 0.3 1.3 -0.8 0.5 -0.6 -1.3 -0.6 0.5 0.3
Ever had prostate specific antigen (PSA) test 0.3 0.3 1.5 0.3 -0.5 -0.4 -0.7 -0.3 -0.6 -1.2 -0.8 -0.6 -0.2 -0.5 -0.3 -0.3 -0.5 -0.8 0.3 -0.4 -0.4 -0.6 -0.5 -0.3 -0.5 -0.5 0.7 -0.6 -0.2 -0.3 -0.1 -0.5
Fractured/broken bones in last 5 years 0.1 0.2 1.7 1.3 0.1 0.9 -0.2 -0.9 0.1 -0.1 0.3 -0.2 -0.5 0.1 0.2 0.1 0.1 -0.1 -0.3 0.2 0.1 -0.1 0.1 -0.3 -0.8 -0.2 -0.2 0.2 0.1 0.4 -0.2 0.3
Age started oral contraceptive pill 9.9 12.4 20.2 -1.6 3.4 2.8 2.9 1.4 3.7 4.5 3.9 4.0 1.9 3.7 3.8 3.7 3.7 4.2 4.0 3.7 3.8 3.7 4.0 3.5 -2.8 3.9 -3.7 3.3 3.3 3.8 3.7 3.7
Diastolic blood pressure, automated reading 0.2 0.5 2.8 0.5 -0.1 -0.2 0.2 -0.7 0.7 0.7 0.1 0.4 1.4 0.7 0.7 0.9 0.6 0.9 -0.7 0.9 -0.1 0.3 0.5 0.6 0.9 0.4 -0.3 0.4 1.7 -0.1 0.8 0.4
Ever depressed for a whole week 0.4 0.5 3.0 0.5 0.3 -0.6 -0.2 -1.4 0.6 0.2 0.6 0.2 -1.7 0.8 0.4 0.4 0.8 0.3 0.7 0.8 0.5 0.8 0.7 0.4 -0.3 0.8 -1.4 -0.3 0.6 0.5 0.5 0.3
Unable to work because of sickness or disability 0.3 0.4 1.7 -1.3 0.3 0.6 -0.3 -0.9 0.7 -0.5 0.6 0.2 0.2 0.6 0.4 0.8 0.7 0.6 -0.1 0.6 0.9 0.5 0.5 0.4 -0.9 0.2 -0.4 0.6 0.5 0.8 -0.2 -0.7
Commuting to job workplace: Cycle 1.0 1.2 2.7 -1.4 1.4 1.3 1.6 0.7 1.0 1.4 1.0 0.9 1.2 0.9 0.6 0.8 1.0 0.9 1.1 0.9 0.7 1.2 1.0 1.4 -1.2 0.9 -1.1 0.9 -0.1 1.6 0.8 0.7
Myopia 0.5 0.8 2.6 0.2 0.5 1.1 0.6 -0.4 0.9 1.1 0.7 0.7 0.9 0.9 0.5 0.8 0.9 1.3 0.9 0.8 0.3 0.9 0.9 0.6 -1.5 0.5 -0.9 0.8 1.6 0.6 1.0 0.7
Vascular/heart problems diagnosed by doctor 1.5 4.1 6.6 0.7 -1.9 -2.0 -1.6 -0.9 -2.4 -2.5 -2.1 -2.2 -1.4 -2.5 -2.5 -2.2 -2.5 -2.3 -1.7 -2.5 -2.0 -2.3 -2.3 -2.1 -0.5 -1.8 2.3 -2.6 -2.1 -1.6 -1.8 -1.7
Cholesterol lowering medication 3.0 4.4 8.4 -1.0 2.2 0.6 2.1 1.8 2.3 1.6 1.9 2.5 1.4 2.3 2.5 2.1 2.3 2.4 1.6 2.3 2.4 2.4 2.5 2.5 -0.3 2.0 -2.5 1.7 2.0 1.8 2.9 2.5
Medication: Omeprazole (e.g. Zanprol) 1.1 1.3 3.6 1.0 0.8 0.2 0.6 -0.8 1.1 1.6 1.0 1.0 1.9 1.2 1.1 1.1 1.2 1.4 0.2 1.3 1.1 1.0 1.2 1.3 -0.3 1.9 -0.7 0.5 1.6 0.9 1.6 1.5
Pain experienced in last month 0.2 0.4 3.0 -1.7 -0.6 -0.8 0.1 -0.3 -0.1 -0.3 -0.0 0.3 1.1 -0.1 -0.1 0.2 -0.2 -0.3 -0.2 -0.3 -0.6 -0.4 -0.4 -0.5 1.1 0.0 0.5 0.1 -1.0 -0.2 -1.3 -0.5
Supplements: Calcium 0.3 0.3 3.8 -0.2 -0.4 2.0 0.5 -0.1 -0.3 -0.1 0.1 0.3 0.9 -0.4 -0.4 -0.4 -0.3 0.1 -1.3 -0.4 -0.3 -0.2 -0.3 0.0 -0.0 -0.1 0.4 0.1 -0.3 0.3 -0.2 -0.4
Basal cell carcinoma (self-reported) 0.6 0.8 3.3 1.2 -0.7 -1.8 -0.3 -1.6 -0.8 -1.1 -0.7 -1.0 -0.1 -0.8 -0.5 -0.9 -0.8 -1.2 -0.5 -0.6 -0.4 -0.8 -0.8 -1.2 0.4 -0.6 1.0 -1.0 -0.5 -1.1 -0.2 0.0
Heart attack/myocardial infarction (self-reported) 0.8 1.0 7.1 -0.6 0.8 2.7 -0.7 -1.2 1.0 1.5 1.3 0.5 -0.1 1.0 1.3 0.2 1.1 0.7 1.2 1.0 1.1 0.8 0.8 0.6 -0.2 0.6 -0.7 1.0 0.9 0.4 0.1 0.1
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 5.0 -0.0 0.8 -2.2 0.5 0.6 -0.1 -0.9 -0.3 0.1 -1.5 -0.2 0.1 -0.1 -0.2 0.0 0.2 -0.1 0.6 0.5 0.3 0.5 0.5 0.7 -0.6 -1.1 -1.2 0.1 1.4 1.4
Heart disease (siblings) 0.9 1.1 3.0 0.1 0.9 1.1 -0.2 -0.5 1.2 1.2 0.9 0.8 1.5 1.2 1.6 1.0 1.3 1.0 0.5 1.3 0.9 1.0 1.1 1.0 -0.9 0.8 -1.4 1.0 1.7 0.9 1.1 0.7
Alcohol drinker status: Previous 0.7 0.8 2.9 0.0 -0.7 0.9 -0.8 1.2 -0.9 -0.4 -0.6 -0.3 -0.0 -0.8 -0.5 -1.0 -0.8 -0.4 -1.7 -0.9 -0.2 -0.8 -0.8 -0.9 -1.2 -1.2 1.0 -1.3 -1.2 -0.4 -1.2 -1.1
Pack years of smoking 0.4 0.5 1.8 -0.1 0.4 0.6 -0.4 -1.3 0.8 0.6 0.6 0.6 0.3 0.8 0.7 0.5 0.9 1.1 -0.9 0.9 0.6 0.7 0.7 0.7 -0.5 0.9 -0.5 1.1 1.3 0.3 0.5 0.1
Impedance of whole body 1.3 6.8 20.0 -2.6 2.8 1.8 0.9 1.1 3.0 3.9 3.6 2.9 -0.0 3.0 3.0 2.5 2.9 2.6 3.1 2.7 2.4 2.6 2.7 2.1 -1.0 3.2 -1.9 4.5 2.0 2.5 1.2 2.5
Leg fat mass (left) 5.8 22.5 36.0 3.4 -5.9 -3.0 -4.8 -3.5 -5.1 -5.7 -6.0 -5.6 -2.1 -5.1 -4.6 -4.6 -5.0 -5.0 -5.0 -4.7 -4.2 -5.3 -5.1 -4.0 2.6 -5.6 4.6 -6.0 -2.3 -5.0 -4.0 -6.0
Arm predicted mass (left) 3.1 16.0 33.5 3.0 -4.4 -3.1 -3.2 -2.7 -4.5 -5.3 -5.1 -4.7 -1.7 -4.5 -4.1 -4.0 -4.5 -4.2 -3.8 -4.2 -3.1 -4.5 -4.4 -3.5 1.7 -4.3 3.8 -5.8 -2.9 -4.2 -3.1 -4.6