Best TWAS P=1.61e-08 · Best GWAS P=6.34e-08 conditioned to 0.217
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue (Male) | CEP57 | 0.08 | 0.06 | lasso | 2 | 0.03 | 0.05780 | -4.9 | -5.3 | 9.9e-08 | 0.85 | 0.05 | 0.45 | FALSE |
2 | GTEx | Esophagus Mucosa | AP001877.1 | 0.09 | 0.00 | lasso | 3 | 0.00 | 0.54200 | -4.9 | -5.6 | 1.6e-08 | 0.84 | 0.05 | 0.64 | TRUE |
3 | GTEx | Esophagus Muscularis | CEP57 | 0.15 | 0.05 | enet | 21 | 0.06 | 0.00009 | -3.8 | -5.3 | 9.1e-08 | 0.83 | 0.06 | 0.93 | FALSE |
4 | GTEx | Liver | CEP57 | 0.24 | 0.10 | enet | 23 | 0.01 | 0.20800 | -4.8 | -5.2 | 2.2e-07 | 0.85 | 0.05 | 0.76 | FALSE |