Best TWAS P=1.45e-07 · Best GWAS P=4.79e-08 conditioned to 0.0291
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RP5-1115A15.1 | 0.14 | 0.07 | enet | 20 | 0.10 | 2.6e-08 | 5.0 | -5.3 | 1.5e-07 | -0.78 | 0.07 | 0.92 | FALSE |
| 2 | GTEx | Lung | RERE | 0.07 | 0.05 | lasso | 4 | 0.05 | 2.0e-04 | 5.2 | -5.2 | 1.5e-07 | -0.94 | 0.03 | 0.97 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | RP5-1115A15.1 | 0.08 | 0.04 | enet | 8 | 0.04 | 3.0e-03 | 5.3 | -5.2 | 1.7e-07 | -0.91 | 0.02 | 0.94 | FALSE |
| 4 | GTEx | Thyroid | RP5-1115A15.1 | 0.09 | 0.12 | lasso | 2 | 0.09 | 1.5e-07 | 5.0 | -5.1 | 3.1e-07 | -0.80 | 0.10 | 0.90 | FALSE |
| 5 | METSIM | Adipose | RERE | 0.08 | 0.12 | lasso | 17 | 0.13 | 1.8e-19 | -4.1 | -5.3 | 1.4e-07 | -0.78 | 0.60 | 0.38 | TRUE |
| 6 | NTR | Blood | RERE | 0.04 | 0.04 | lasso | 8 | 0.03 | 2.0e-11 | 5.3 | -5.2 | 2.2e-07 | -0.88 | 0.02 | 0.98 | FALSE |
| 7 | YFS | Blood | RERE | 0.09 | 0.15 | lasso | 4 | 0.16 | 5.7e-49 | 5.0 | -5.1 | 2.7e-07 | -0.80 | 0.11 | 0.89 | FALSE |