Best TWAS P=1.08e-08 · Best GWAS P=3.16e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RABGAP1L | 0.10 | 0.09 | blup | 647 | 0.11 | 4.0e-13 | -4.4 | -5.2 | 1.8e-07 | 0.89 | 0.26 | 0.74 | FALSE |
| 2 | GTEx | Brain Putamen basal ganglia | DARS2 | 0.13 | 0.01 | enet | 14 | 0.00 | 3.7e-01 | -5.8 | 5.6 | 1.9e-08 | -0.96 | 0.02 | 0.87 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | RABGAP1L | 0.23 | 0.03 | enet | 25 | 0.10 | 4.8e-09 | -5.0 | -5.2 | 1.8e-07 | 0.71 | 0.48 | 0.51 | FALSE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | RABGAP1L | 0.12 | 0.03 | blup | 305 | 0.03 | 1.2e-02 | -5.9 | -5.7 | 1.1e-08 | 0.97 | 0.02 | 0.92 | TRUE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | RABGAP1L | 0.12 | 0.01 | lasso | 6 | 0.03 | 5.0e-04 | -5.8 | -5.1 | 2.9e-07 | 0.88 | 0.03 | 0.97 | FALSE |