Best TWAS P=8.44e-08 · Best GWAS P=1.15e-07 conditioned to 0.0507
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 5 | GTEx | Skin Sun Exposed Lower leg | CYB561D2 | 0.13 | 0.02 | lasso | 3 | 0.05 | 5.7e-05 | 3.6 | -5.4 | 8.4e-08 | -0.75 | 0.02 | 0.96 | TRUE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | CYB561D2 | 0.08 | 0.01 | enet | 7 | 0.02 | 2.3e-02 | 4.7 | -5.3 | 1.1e-07 | -0.73 | 0.05 | 0.74 | FALSE |
| 2 | GTEx | Esophagus Muscularis | RASSF1 | 0.10 | 0.00 | lasso | 7 | 0.01 | 8.7e-02 | 4.7 | 5.2 | 1.7e-07 | 0.85 | 0.04 | 0.73 | FALSE |
| 3 | GTEx | Muscle Skeletal | SEMA3B-AS1 | 0.17 | 0.01 | lasso | 7 | 0.02 | 8.3e-03 | 5.3 | 5.2 | 2.3e-07 | 0.78 | 0.02 | 0.95 | FALSE |
| 1 | GTEx | Esophagus Mucosa | CYB561D2 | 0.07 | 0.02 | lasso | 4 | 0.02 | 3.1e-02 | 5.3 | -5.1 | 2.7e-07 | -0.93 | 0.02 | 0.93 | FALSE |
| 6 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | CYB561D2 | 0.08 | 0.04 | blup | 17 | 0.08 | 9.3e-04 | 5.1 | -5.1 | 3.0e-07 | -0.79 | 0.00 | 0.63 | FALSE |