[Hub]/) : Traits : Worry too long after embarrassment :

chr11:112,486,568-113,952,419

Best TWAS P=1.5e-10 · Best GWAS P=4e-11 conditioned to 0.368

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Heart Left Ventricle TTC12 0.39 0.24 enet 36 0.38 2.5e-21 6.1 5.3 1.2e-07 0.65 0.41 0.59 FALSE
2 The Cancer Genome Atlas Breast Invasive Carcinoma TTC12 0.19 0.12 blup 48 0.15 1.1e-28 6.1 5.2 1.5e-07 0.75 0.05 0.95 FALSE
3 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ANKK1 0.04 0.02 blup 66 0.03 5.0e-04 4.6 6.2 5.9e-10 0.75 0.10 0.64 FALSE
4 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ANKK1 0.04 0.03 blup 67 0.04 6.3e-05 4.8 -5.7 9.5e-09 -0.69 0.29 0.56 FALSE
5 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma TTC12 0.37 0.22 enet 5 0.22 1.1e-12 4.8 5.2 2.2e-07 0.79 0.25 0.75 FALSE
6 The Cancer Genome Atlas Brain Lower Grade Glioma TTC12 0.33 0.28 blup 48 0.30 1.4e-34 6.0 5.4 6.3e-08 0.77 0.06 0.94 FALSE
7 The Cancer Genome Atlas Liver Hepatocellular Carcinoma ANKK1 0.08 0.02 blup 66 0.04 5.6e-03 4.5 -5.3 1.5e-07 -0.73 0.06 0.69 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma DRD2 0.06 0.07 lasso 2 0.07 6.6e-09 -6.2 6.2 5.3e-10 0.35 0.08 0.92 TRUE
9 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TTC12 0.25 0.12 blup 48 0.12 2.4e-08 4.8 5.3 8.9e-08 0.84 0.07 0.93 FALSE
10 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma TTC12 0.36 0.30 lasso 3 0.29 6.0e-12 6.0 6.0 2.0e-09 0.79 0.06 0.94 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma TTC12 0.21 0.20 lasso 4 0.22 1.2e-22 6.0 5.6 1.7e-08 0.82 0.07 0.93 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma TTC12 0.25 0.10 enet 10 0.17 3.6e-12 4.8 5.3 1.1e-07 0.78 0.03 0.97 FALSE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors TTC12 0.07 0.06 blup 48 0.04 1.6e-02 4.8 6.4 1.5e-10 0.88 0.02 0.71 TRUE