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chr11:112,486,568-113,952,419

Best TWAS P=1.5e-10 · Best GWAS P=4e-11 conditioned to 0.368

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Heart Left Ventricle	TTC12	0.39	0.24	enet	36	0.38	2.5e-21	6.1	5.3	1.2e-07	0.65	0.41	0.59	FALSE
2	The Cancer Genome Atlas	Breast Invasive Carcinoma	TTC12	0.19	0.12	blup	48	0.15	1.1e-28	6.1	5.2	1.5e-07	0.75	0.05	0.95	FALSE
3	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ANKK1	0.04	0.02	blup	66	0.03	5.0e-04	4.6	6.2	5.9e-10	0.75	0.10	0.64	FALSE
4	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ANKK1	0.04	0.03	blup	67	0.04	6.3e-05	4.8	-5.7	9.5e-09	-0.69	0.29	0.56	FALSE
5	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TTC12	0.37	0.22	enet	5	0.22	1.1e-12	4.8	5.2	2.2e-07	0.79	0.25	0.75	FALSE
6	The Cancer Genome Atlas	Brain Lower Grade Glioma	TTC12	0.33	0.28	blup	48	0.30	1.4e-34	6.0	5.4	6.3e-08	0.77	0.06	0.94	FALSE
7	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ANKK1	0.08	0.02	blup	66	0.04	5.6e-03	4.5	-5.3	1.5e-07	-0.73	0.06	0.69	FALSE
8	The Cancer Genome Atlas	Lung Adenocarcinoma	DRD2	0.06	0.07	lasso	2	0.07	6.6e-09	-6.2	6.2	5.3e-10	0.35	0.08	0.92	TRUE
9	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TTC12	0.25	0.12	blup	48	0.12	2.4e-08	4.8	5.3	8.9e-08	0.84	0.07	0.93	FALSE
10	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	TTC12	0.36	0.30	lasso	3	0.29	6.0e-12	6.0	6.0	2.0e-09	0.79	0.06	0.94	FALSE
11	The Cancer Genome Atlas	Prostate Adenocarcinoma	TTC12	0.21	0.20	lasso	4	0.22	1.2e-22	6.0	5.6	1.7e-08	0.82	0.07	0.93	FALSE
12	The Cancer Genome Atlas	Stomach Adenocarcinoma	TTC12	0.25	0.10	enet	10	0.17	3.6e-12	4.8	5.3	1.1e-07	0.78	0.03	0.97	FALSE
13	The Cancer Genome Atlas	Testicular Germ Cell Tumors	TTC12	0.07	0.06	blup	48	0.04	1.6e-02	4.8	6.4	1.5e-10	0.88	0.02	0.71	TRUE