Best TWAS P=1.23e-09 · Best GWAS P=4.06e-07 conditioned to 0.946
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C16orf3 | 0.19 | 0.10 | enet | 17 | 0.10 | 2.7e-12 | 5.1 | 5.1 | 2.8e-07 | 0.86 | 0 | 1.00 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | DBNDD1 | 0.25 | 0.02 | lasso | 7 | 0.03 | 2.6e-03 | 5.1 | 5.3 | 1.3e-07 | 0.92 | 0 | 0.99 | FALSE |
| 3 | GTEx | Artery Tibial | DBNDD1 | 0.31 | 0.20 | enet | 20 | 0.27 | 2.0e-21 | 5.1 | 5.7 | 1.2e-08 | 0.86 | 0 | 1.00 | FALSE |
| 4 | GTEx | Brain Cerebellum | GAS8 | 0.60 | 0.41 | lasso | 10 | 0.37 | 8.0e-12 | 5.1 | 5.3 | 1.4e-07 | 0.99 | 0 | 1.00 | FALSE |
| 5 | GTEx | Brain Cerebellum | URAHP | 0.60 | 0.38 | lasso | 9 | 0.33 | 1.7e-10 | 5.1 | 5.3 | 9.3e-08 | 0.97 | 0 | 1.00 | FALSE |
| 6 | GTEx | Colon Sigmoid | DBNDD1 | 0.42 | 0.13 | lasso | 5 | 0.18 | 7.6e-07 | 5.1 | 5.1 | 2.8e-07 | 0.91 | 0 | 1.00 | FALSE |
| 7 | GTEx | Stomach | DBNDD1 | 0.16 | 0.07 | lasso | 2 | 0.11 | 4.2e-06 | 5.1 | 6.1 | 1.2e-09 | 0.84 | 0 | 0.98 | TRUE |