Best TWAS P=2.14e-08 · Best GWAS P=2.15e-07 conditioned to 0.95
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | MNT | 0.14 | 0.05 | lasso | 5 | 0.04 | 3.8e-04 | -5.1 | -5.6 | 2.1e-08 | 0.93 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Lung | RP1-59D14.1 | 0.08 | 0.03 | lasso | 2 | 0.01 | 8.6e-02 | -5.1 | -5.5 | 3.6e-08 | 0.97 | 0.00 | 0.94 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | MNT | 0.16 | 0.06 | lasso | 7 | 0.04 | 2.6e-03 | -5.2 | -5.1 | 3.1e-07 | 0.98 | 0.00 | 0.96 | FALSE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | RP1-59D14.1 | 0.16 | 0.07 | lasso | 5 | 0.03 | 1.2e-02 | -5.2 | -5.3 | 1.5e-07 | 0.97 | 0.00 | 0.94 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | MNT | 0.10 | 0.09 | enet | 16 | 0.08 | 5.1e-07 | -5.2 | -5.1 | 2.8e-07 | 0.89 | 0.00 | 1.00 | FALSE |
| 6 | GTEx | Skin Sun Exposed Lower leg | RP1-59D14.1 | 0.11 | 0.07 | lasso | 4 | 0.06 | 1.8e-05 | -5.2 | -5.3 | 1.1e-07 | 0.99 | 0.00 | 1.00 | FALSE |
| 7 | GTEx | Stomach | RP1-59D14.5 | 0.14 | 0.04 | enet | 23 | 0.06 | 8.5e-04 | -5.1 | -5.6 | 2.3e-08 | 0.74 | 0.01 | 0.96 | FALSE |