Best TWAS P=9.52e-09 · Best GWAS P=9.17e-11 conditioned to 0.00255
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ATG7 | 0.07 | 0.07 | lasso | 3 | 0.07 | 3.3e-09 | -4.9 | 5.6 | 1.8e-08 | -0.89 | 0.10 | 0.90 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | VGLL4 | 0.04 | 0.02 | blup | 511 | 0.02 | 7.8e-04 | -6.2 | -5.3 | 9.9e-08 | 0.79 | 0.06 | 0.90 | FALSE |
| 3 | GTEx | Adipose Visceral Omentum | ATG7 | 0.18 | 0.06 | lasso | 4 | 0.06 | 2.9e-04 | -5.0 | 5.3 | 9.2e-08 | -0.81 | 0.26 | 0.66 | FALSE |
| 4 | GTEx | Muscle Skeletal | ATG7 | 0.06 | 0.02 | lasso | 4 | 0.03 | 8.6e-04 | -5.9 | 5.7 | 9.5e-09 | -0.90 | 0.04 | 0.93 | TRUE |
| 5 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ATG7 | 0.06 | 0.01 | lasso | 2 | 0.02 | 1.2e-02 | -3.7 | 5.4 | 8.8e-08 | -0.81 | 0.13 | 0.32 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ATG7 | 0.05 | 0.05 | lasso | 4 | 0.03 | 3.2e-04 | -5.5 | 5.6 | 2.5e-08 | -0.87 | 0.04 | 0.92 | FALSE |