Best TWAS P=7.85e-09 · Best GWAS P=1.88e-08 conditioned to 0.232
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | RERE | 0.13 | 0.16 | lasso | 3 | 0.16 | 7.2e-11 | -5.4 | 5.4 | 6.8e-08 | -0.86 | 0.03 | 0.97 | FALSE |
| 2 | GTEx | Esophagus Mucosa | RP5-1115A15.1 | 0.06 | 0.06 | lasso | 4 | 0.05 | 3.0e-04 | -5.4 | 5.8 | 7.9e-09 | -0.87 | 0.05 | 0.88 | TRUE |
| 3 | GTEx | Lung | RERE | 0.07 | 0.05 | lasso | 4 | 0.05 | 2.0e-04 | -5.0 | 5.2 | 1.9e-07 | -0.98 | 0.03 | 0.97 | FALSE |
| 4 | GTEx | Lung | RP5-1115A15.1 | 0.05 | 0.08 | lasso | 1 | 0.07 | 1.0e-05 | -5.2 | 5.2 | 2.4e-07 | -0.86 | 0.05 | 0.92 | FALSE |
| 5 | GTEx | Skin Not Sun Exposed Suprapubic | RP5-1115A15.1 | 0.08 | 0.04 | enet | 8 | 0.04 | 3.0e-03 | -5.5 | 5.6 | 2.2e-08 | -0.97 | 0.02 | 0.95 | FALSE |
| 6 | GTEx | Whole Blood | RERE | 0.19 | 0.15 | lasso | 4 | 0.13 | 2.7e-12 | -5.4 | 5.4 | 5.7e-08 | -0.86 | 0.03 | 0.97 | FALSE |