Best TWAS P=1.4e-07 · Best GWAS P=5.85e-07 conditioned to 0.0713
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | KIF2A | 0.05 | 0.02 | lasso | 4 | 0.02 | 0.0011 | 5.0 | -5.1 | 2.7e-07 | -0.94 | 0.01 | 0.88 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | IPO11 | 0.03 | 0.00 | blup | 127 | 0.01 | 0.0297 | 3.3 | 5.3 | 1.4e-07 | 0.71 | 0.02 | 0.24 | TRUE |