TWAS hub - KIF2A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Aorta	0.0760	0.0350	3.6e-04	0.052	NA	0.051	NA	0.001	7.8e-04	NA	8.8e-04	NA	2.8e-01
2	GTEx	Artery Tibial	0.0400	0.0190	1.1e-03	0.038	NA	0.043	NA	0.035	5.4e-04	NA	2.6e-04	NA	8.4e-04
3	GTEx	Esophagus Muscularis	0.1370	0.0630	5.0e-04	0.016	NA	0.029	NA	0.046	3.5e-02	NA	6.9e-03	NA	8.5e-04
4	GTEx	Heart Left Ventricle	0.1164	0.0556	3.8e-03	-0.004	NA	-0.005	NA	-0.005	6.9e-01	NA	9.4e-01	NA	8.8e-01
5	GTEx	Nerve Tibial	0.0787	0.0416	4.2e-03	-0.002	NA	-0.004	NA	-0.001	5.0e-01	NA	8.1e-01	NA	3.9e-01
6	GTEx	Testis	0.0700	0.0310	1.1e-03	0.004	NA	0.015	NA	0.022	2.1e-01	NA	6.6e-02	NA	3.5e-02
7	METSIM	Adipose	0.0514	0.0262	4.3e-03	0.017	0.013	0.014	0.015	0.017	1.1e-03	4.1e-03	3.0e-03	0.0022	1.1e-03
8	YFS	Blood	0.0111	0.0051	7.0e-04	0.010	0.005	0.004	0.005	0.007	1.8e-04	5.0e-03	1.9e-02	0.0069	2.1e-03
9	TCGA	Breast Invasive Carcinoma	0.0486	0.0232	1.1e-05	0.018	0.025	0.022	NA	0.019	8.6e-05	5.4e-06	1.7e-05	NA	5.5e-05
10	TCGA	Lung Adenocarcinoma	0.0557	0.0359	9.4e-03	0.018	0.002	0.005	NA	0.008	2.7e-03	1.5e-01	7.7e-02	NA	3.9e-02
11	TCGA	Lung Squamous Cell Carcinoma	0.0548	0.0268	1.7e-03	0.033	0.014	0.018	NA	0.021	1.1e-04	7.9e-03	3.2e-03	NA	1.7e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Guilty feelings	7.1	10.6	18.2	4.0	4.2	3.3	2.8	3.7	3.6	0.4	4.3	-1.9	-2.8	-2.6
Frequency of depressed mood in last 2 weeks	6.6	9.2	15.9	3.8	3.7	3.5	2.6	3.2	3.4	0.2	4.0	-1.3	-2.8	-2.7
Depression (Nagel 2018)	5.6	8.4	17.9	3.6	3.6	4.2	2.1	2.9	2.5	0.0	4.0	-1.3	-2.4	-2.3
Neuroticism (Nagel 2018)	5.4	12.6	23.2	4.6	4.8	3.4	3.7	4.7	3.7	0.3	4.8	-1.4	-2.2	-2.0
Illnesses of father: High blood pressure	5.1	6.3	11.9	3.3	3.0	1.5	3.4	2.2	3.0	-1.5	2.7	2.4	1.7	1.7
Diastolic blood pressure, automated reading	5.1	15.9	43.2	-0.3	-0.1	0.3	3.3	0.3	1.3	-5.8	-0.7	6.6	6.5	6.5
High blood pressure	5.0	13.8	29.6	3.2	3.2	3.3	5.3	2.3	3.4	-5.4	2.5	3.9	3.4	3.6
Tense / ‘highly strung’	4.8	8.0	16.0	4.0	3.9	2.8	2.0	2.4	3.2	0.6	4.0	-1.0	-2.5	-2.4
Seen doctor (GP) for nerves, anxiety, tension or depression	4.7	7.1	19.3	4.4	3.4	3.1	2.8	2.7	2.0	-0.6	3.7	-0.4	-1.7	-1.5
Worry too long after embarrassment	4.7	7.9	19.1	3.6	3.7	2.1	3.6	4.4	2.4	-0.2	3.3	-1.4	-1.8	-1.5
Vitamin and mineral supplements	4.6	6.3	12.7	3.0	3.1	3.6	2.4	3.1	3.1	-0.4	3.3	-0.3	-1.0	-0.9
Depression (self-reported)	4.4	5.3	11.2	3.1	2.8	1.5	2.1	3.3	1.6	1.4	2.5	-2.0	-2.1	-1.9
Hypertension (Self-reported)	4.4	12.2	26.4	3.0	3.1	3.4	4.8	1.9	3.3	-5.1	2.5	3.7	3.1	3.2
Glaucoma (self-reported)	4.2	4.9	9.8	2.5	3.0	1.9	2.9	3.1	3.1	0.3	2.6	0.6	0.3	0.5
Ever had prostate specific antigen (PSA) test	4.2	4.8	7.4	2.3	2.7	2.3	2.7	0.9	2.6	-2.7	2.5	2.2	0.9	1.0
Multivitamins +/- minerals	4.1	5.2	13.3	-2.7	-3.0	-3.6	-1.7	-2.0	-2.9	0.3	-2.9	0.5	1.3	1.3
Major Depression (MDD)	4.0	4.8	14.5	2.7	2.1	2.2	3.8	3.0	2.2	-1.0	2.3	1.1	0.7	0.8
Average weekly fortified wine intake	4.0	4.6	15.2	1.4	1.6	2.0	3.9	1.7	1.7	-3.2	1.0	2.0	1.8	1.9
Systolic Blood Pressure	3.9	19.4	50.8	-0.7	-1.0	-0.3	3.1	-1.3	0.5	-7.0	-1.2	7.1	7.1	7.0
Systolic blood pressure, automated reading	3.9	11.3	31.5	-1.9	-1.6	-1.3	0.9	-1.9	0.1	-4.3	-2.1	5.3	5.6	5.5
Falls in the last year	3.6	4.8	8.6	2.3	2.6	2.9	1.0	2.8	1.8	1.7	2.9	-1.5	-1.9	-1.8
Seen a psychiatrist for nerves, anxiety, tension or depression	3.6	4.7	11.3	3.4	2.8	2.7	2.0	2.0	2.7	0.1	2.8	0.2	-1.1	-1.0
Loneliness, isolation	3.6	5.0	10.1	1.9	1.8	1.7	0.6	2.8	1.1	2.3	2.2	-2.7	-3.2	-3.0
Blood Platelet Count	3.5	40.1	91.6	9.6	8.7	4.2	1.3	3.5	6.6	4.6	8.0	-3.5	-7.1	-7.1
Frequency of tenseness / restlessness in last 2 weeks	3.5	5.5	8.0	2.6	2.7	2.7	1.9	2.6	2.5	-0.0	2.8	-1.3	-2.5	-2.4
Headache pain in last month	3.5	6.0	11.6	2.9	3.3	2.3	3.3	3.4	2.1	-0.7	3.1	-0.8	-1.4	-1.3
Vascular/heart problems diagnosed by doctor	3.5	9.7	20.4	-3.1	-3.1	-2.7	-4.5	-1.9	-2.9	4.3	-2.4	-3.1	-2.5	-2.7
Neuroticism (2016)	3.4	4.9	17.6	2.0	1.9	1.8	3.8	4.2	2.0	-1.0	2.4	-0.2	0.2	0.2
Worrier / anxious feelings	3.4	6.5	21.7	2.5	2.4	0.7	3.6	4.7	2.1	0.2	2.9	-2.0	-2.1	-1.8
Frequency of tiredness / lethargy in last 2 weeks	3.3	5.4	11.8	2.4	2.2	2.4	0.7	1.7	1.2	0.9	2.5	-2.7	-3.4	-3.4
Medication for cholesterol, blood pressure or diabetes	3.3	5.4	14.8	-3.3	-3.8	-3.0	-2.0	-1.1	-2.5	0.9	-3.4	-0.7	0.9	0.7
Number of full sisters	3.3	4.0	8.5	2.8	2.4	2.0	2.3	2.6	2.9	0.2	2.3	0.8	0.3	0.4
Worry (Nagel 2018)	3.2	6.7	15.6	2.8	2.9	1.3	2.6	3.9	1.8	0.7	3.2	-2.4	-2.7	-2.5
Cardiovascular Disease	3.2	10.4	22.4	2.4	2.1	1.3	4.3	1.9	2.5	-4.7	1.8	4.1	3.9	4.1
Happiness	3.2	3.9	6.6	2.6	2.2	2.5	1.7	1.8	1.3	0.2	2.3	-1.3	-2.3	-2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	3.1	4.1	10.0	2.6	2.4	3.2	0.2	1.2	1.6	0.5	2.2	-1.4	-2.4	-2.4
Neuroticism score	3.1	6.5	13.7	2.5	2.6	1.3	2.5	3.7	1.8	1.1	2.8	-2.7	-3.1	-2.8
Neuroticism	3.0	7.2	19.5	3.2	3.2	1.2	3.1	4.4	2.9	1.0	3.1	-1.8	-1.8	-1.5
Mouth/teeth dental problems: Mouth ulcers	3.0	4.8	11.8	3.4	2.8	2.4	1.4	-0.4	3.2	-1.6	2.5	2.2	0.8	0.7
Schizophrenia vs Biploar Disorder	2.9	3.8	11.6	1.8	1.7	0.8	-0.4	0.3	1.3	1.4	2.1	-1.9	-3.4	-3.4
Serious illness, injury or assault to yourself	2.9	3.5	10.2	2.4	2.4	2.7	1.0	1.3	1.9	0.4	3.2	-0.1	-1.2	-1.2
Medication: Cholesterol lowering	2.9	4.5	11.1	3.1	3.3	1.8	1.1	1.0	2.2	0.4	2.9	-0.7	-2.2	-2.1
Hand grip strength (right)	2.8	7.7	14.2	-3.8	-3.3	-2.7	0.3	-0.5	-2.7	-1.6	-3.5	1.9	3.6	3.6
Supplements: Vitamin C	2.8	3.4	6.9	-2.3	-2.4	-2.0	-2.0	-2.2	-2.6	0.3	-2.4	-0.2	0.5	0.4
Ever depressed for a whole week	2.8	3.4	7.3	2.6	2.4	1.9	2.0	2.1	2.7	-0.2	2.2	-0.0	-0.6	-0.5
Diverticular disease/diverticulitis (self-reported)	2.7	3.2	7.1	2.7	2.6	1.9	2.2	1.6	2.0	-0.0	2.2	-0.3	-1.0	-0.8
Had menopause	2.6	3.2	13.8	-0.5	-0.6	-0.4	-3.7	-3.5	-0.4	1.7	-0.8	-0.4	-1.4	-1.5
Risk taking	2.6	3.8	6.5	2.5	2.0	2.0	1.9	2.5	2.0	1.8	2.5	-0.7	-1.3	-1.2
Exposure to tobacco smoke at home	2.5	2.8	6.0	1.6	1.7	1.6	2.4	1.8	2.1	-1.6	1.7	1.1	0.9	1.1
Qualifications: NVQ or HND or HNC or equivalent	2.5	3.1	6.8	2.2	2.2	1.6	2.2	2.6	1.0	-1.3	2.0	1.1	0.9	1.0
High blood pressure (mother)	2.4	3.4	7.6	0.7	1.1	0.3	2.4	1.2	1.8	-1.8	1.0	2.7	2.5	2.6
Medication for pain relief, constipation, heartburn	2.4	4.2	8.5	-2.4	-2.9	-2.7	-2.4	-1.7	-2.3	1.7	-2.4	-1.2	-0.4	-0.4
Financial situation satisfaction	2.4	3.0	6.4	2.4	1.8	2.5	2.3	1.8	1.6	-0.8	2.2	0.8	0.1	0.2
Supplements: Zinc	2.2	2.3	7.7	-0.5	-0.5	-1.5	-0.4	-1.7	-0.2	-1.6	-0.5	2.8	2.2	2.1
Chest pain or discomfort	2.2	3.1	7.0	1.8	1.8	2.6	1.9	1.3	1.1	-1.1	2.0	-1.6	-1.9	-1.9
Osteoarthritis (self-reported)	2.2	2.9	8.1	-1.6	-1.7	-0.9	-2.1	-2.3	-2.8	-0.6	-2.0	-1.5	-0.8	-0.8
Hair/balding pattern: Pattern 2	2.1	2.7	5.1	-1.6	-1.9	-1.8	-0.7	-1.7	-1.4	-0.7	-2.3	1.4	1.9	1.8
Breastfed as a baby	2.1	2.6	6.1	2.1	2.0	2.3	1.3	1.3	2.5	0.4	2.1	-0.0	-0.7	-0.7
Overall health rating	2.1	4.6	12.8	2.4	1.8	3.6	0.2	1.0	0.9	0.6	2.3	-2.1	-2.9	-2.8
Miserableness	2.1	3.6	10.7	2.0	2.3	1.7	3.3	3.0	1.7	-1.2	1.8	-0.4	-0.3	-0.1
Length of working week for main job	2.0	2.2	4.5	1.7	1.9	2.1	1.2	1.1	1.3	-0.3	1.4	-1.3	-1.7	-1.7
Eye problems/disorders: Glaucoma	2.0	2.4	4.7	1.8	2.0	1.4	2.2	2.1	1.8	-0.2	1.6	0.8	0.6	0.7
Unable to work because of sickness or disability	2.0	2.6	5.1	2.2	1.4	1.5	0.7	1.9	0.9	1.5	2.2	-1.2	-1.8	-1.7
Schizophrenia (2014)	1.9	4.3	10.2	2.2	2.2	0.5	-0.8	0.5	0.8	2.7	2.0	-2.3	-3.2	-3.0
Gout (self-reported)	1.9	2.7	4.9	1.3	1.6	0.2	2.0	1.7	2.2	-1.2	1.4	2.0	1.6	1.8
Medication: Blood pressure	1.9	3.4	8.2	2.2	2.6	2.9	2.1	1.3	1.6	-1.7	2.3	0.7	-0.1	0.1
Intelligence (Savage-Jansen 2018)	1.8	5.4	13.5	-3.2	-3.5	-1.6	-1.1	-1.6	-3.7	-0.9	-3.6	-0.5	1.4	1.4
Lung FVC	1.8	9.1	24.9	4.8	5.0	1.3	2.4	2.4	4.2	-0.0	4.3	1.9	0.5	0.5
Hand grip strength (left)	1.8	4.6	11.4	-2.1	-2.0	-1.5	0.8	-0.1	-1.2	-2.2	-2.3	2.4	3.3	3.4
Medication: Lansoprazole	1.8	2.1	4.5	1.6	1.6	0.3	-0.7	-0.1	1.0	2.1	1.3	-1.1	-2.1	-2.1
Long-standing illness, disability or infirmity	1.8	2.8	10.5	2.4	2.2	3.2	1.2	1.0	1.3	-0.1	2.2	0.2	-0.7	-0.7
Age started oral contraceptive pill	1.8	2.3	7.8	-1.5	-1.4	-0.7	-2.5	-2.8	-1.4	-0.5	-1.7	0.6	0.6	0.6
Emphysema/chronic bronchitis	1.7	1.9	5.2	2.3	1.7	1.7	-0.2	0.0	0.7	-0.2	1.8	-0.8	-1.6	-1.7
Average weekly red wine intake	1.7	2.5	7.2	-1.0	-0.8	-1.2	0.8	-0.6	-0.5	-2.0	-0.7	2.7	2.5	2.4
Pain type(s) experienced in last month: Hip pain	1.7	2.1	4.3	1.9	2.1	1.4	1.3	2.1	1.7	-0.1	1.7	-0.7	-0.9	-0.7
Other serious medical condition/disability diagnosed by doctor	1.6	2.1	5.8	2.4	2.4	1.7	0.0	-0.0	1.6	0.1	2.3	0.9	-0.2	-0.2
Bilateral oophorectomy (both ovaries removed)	1.6	1.8	5.7	1.6	1.6	1.0	2.1	2.4	1.3	-0.7	1.5	0.1	0.1	0.3
Forced expiratory volume in 1-second (FEV1)	1.6	5.4	13.7	2.8	3.4	0.9	3.1	3.7	2.6	-0.1	3.1	0.0	-0.2	-0.1
Wheeze or whistling in the chest in last year	1.6	2.9	7.4	2.5	2.1	2.7	1.1	1.2	1.5	0.0	2.4	-0.4	-1.2	-1.2
Angina (self-reported)	1.6	2.2	6.2	1.6	1.4	0.8	-0.9	-1.3	0.7	0.6	1.1	-1.4	-2.5	-2.5
Illness, injury, bereavement, stress in last 2 years	1.6	2.0	5.8	-2.4	-2.3	-0.9	-1.3	-1.6	-1.2	0.1	-1.8	-1.0	-0.4	-0.4
Friendships satisfaction	1.6	2.0	4.2	1.9	1.9	2.1	1.0	0.9	1.6	-0.6	1.9	-0.1	-0.9	-0.8
Commuting to job workplace: Public transport	1.6	1.9	3.5	-1.4	-1.7	-1.0	-1.2	-1.9	-0.6	-0.8	-1.5	1.4	1.5	1.5
Waist Hip Ratio (WHR)	1.5	6.6	16.4	3.7	3.3	1.8	2.4	3.0	3.6	0.8	4.0	0.1	-0.7	-0.6
Number of treatments/medications taken	1.5	2.7	6.1	2.0	2.5	2.3	1.1	0.0	1.8	-1.7	2.0	1.5	0.5	0.5
Chronic bronchitis/emphysema (father)	1.5	1.8	3.5	1.9	1.2	0.5	0.6	1.1	0.9	1.6	1.4	-1.4	-1.8	-1.7
Hearing difficulty/problems with background noise	1.5	2.4	4.2	1.4	2.0	0.9	2.0	2.1	1.8	0.6	1.4	-1.2	-1.6	-1.5
Qualifications: None of the above	1.5	3.2	10.2	-1.4	-1.1	-0.8	-3.2	-2.1	-1.0	2.3	-1.0	-1.7	-1.7	-1.9
Pulse rate	1.5	2.6	6.0	-2.3	-2.1	-1.6	-0.9	-0.7	-2.4	-1.7	-2.0	0.2	1.1	1.1
Peak expiratory flow (PEF)	1.5	3.4	12.0	1.5	2.0	0.4	3.2	3.5	2.0	-0.5	2.0	0.0	0.3	0.4
Medication: Amlodipine	1.5	2.0	4.0	1.4	1.7	1.5	2.0	1.0	1.5	-1.9	1.3	1.1	0.8	0.9
Medication: Aspirin	1.5	1.9	4.7	1.9	2.2	1.7	1.4	1.0	1.4	-1.0	1.7	-0.4	-1.0	-0.9
Qualifications: nursing, teaching	1.5	2.4	7.1	0.3	0.9	0.3	2.7	0.9	1.3	-2.1	-0.2	1.6	2.0	2.2
Ever taken oral contraceptive pill	1.5	1.7	3.5	1.2	1.2	1.9	1.8	1.8	1.5	-0.5	1.7	-0.2	-0.5	-0.4
Schizophrenia (2018)	1.4	3.0	7.5	1.6	1.4	0.1	-1.2	0.1	-0.3	2.6	1.3	-2.1	-2.7	-2.6
Trunk fat percentage	1.4	5.4	12.2	2.9	3.4	1.9	2.7	2.7	3.5	0.8	2.6	-0.3	-1.1	-1.0
Forced vital capacity (FVC)	1.4	5.4	10.2	2.7	3.2	0.8	3.1	3.0	2.8	-1.0	3.2	1.4	0.9	0.9
Mouth/teeth dental problems: Dentures	1.4	2.3	6.1	-1.2	-2.1	0.1	-1.7	-1.9	-2.2	0.1	-2.5	-1.1	-0.5	-0.5
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	3.7	0.9	1.4	1.3	1.3	0.0	1.4	-1.9	0.8	1.9	1.5	1.4
Hair/balding pattern: Pattern 4	1.4	3.4	7.9	-0.7	-0.7	-1.2	-2.2	-0.5	-1.8	2.4	-0.8	-2.8	-2.4	-2.4
Reason for reducing amount of alcohol drunk: Health precaution	1.4	1.6	9.0	1.3	1.8	0.5	0.4	0.1	3.0	0.4	1.5	0.9	0.1	0.2
Mood swings	1.4	2.4	5.9	1.7	1.9	1.3	2.0	2.4	1.8	0.4	1.8	-0.8	-0.9	-0.8
Number of self-reported non-cancer illnesses	1.4	2.5	6.0	2.3	2.3	1.2	2.1	1.2	1.9	-0.5	2.4	0.3	-0.5	-0.5
Depressed Affect (Nagel 2018)	1.3	2.7	5.3	2.0	2.2	1.9	1.7	2.3	1.5	0.6	2.1	-0.9	-0.9	-0.8
Sensitivity / hurt feelings	1.3	2.1	5.4	1.4	1.5	1.8	0.5	0.7	0.8	0.6	1.0	-1.7	-2.3	-2.3
Townsend deprivation index at recruitment	1.3	1.8	5.3	1.3	1.2	1.1	1.8	2.3	2.0	0.6	1.4	-1.0	-0.5	-0.3
Supplements: Glucosamine	1.3	1.7	4.0	-1.1	-1.1	-0.3	-1.2	-2.0	-1.4	-1.8	-1.8	0.8	1.0	1.0
Medication: Ventolin 100micrograms inhaler	1.3	1.7	5.2	0.6	1.0	0.8	-0.8	-0.2	0.5	1.5	0.7	-1.4	-2.3	-2.3
Body fat percentage	1.3	5.1	10.9	2.8	3.3	2.1	2.5	2.5	3.3	0.8	2.5	-0.4	-1.1	-1.0
Had major operations	1.3	1.5	8.8	1.1	0.5	3.0	0.6	-0.7	-0.0	-2.1	0.7	-0.1	-0.1	-0.2
Family relationship satisfaction	1.3	1.6	3.4	1.6	1.1	1.8	1.7	0.7	1.3	-0.4	1.4	1.4	0.5	0.6
Ever had bowel cancer screening	1.3	1.5	4.9	1.1	1.1	1.1	0.2	-0.7	0.2	0.7	0.6	-1.5	-2.2	-2.2
Diabetes diagnosed by doctor	1.3	2.1	7.2	0.9	1.4	0.7	-0.2	0.5	0.4	0.4	0.7	-2.3	-2.7	-2.6
Medication: Aspirin	1.3	1.7	4.4	1.9	2.1	1.4	1.1	1.1	1.2	-0.6	1.7	-0.3	-0.8	-0.7
High cholesterol (Self-reported)	1.3	2.2	5.7	1.8	1.9	-0.2	1.3	0.5	2.4	-0.7	1.6	1.8	1.3	1.3
Average weekly beer plus cider intake	1.3	1.9	3.3	1.4	1.1	1.8	0.3	1.5	0.9	1.1	1.5	-1.7	-1.6	-1.6
Bipolar Disorder (2011)	1.2	1.2	2.7	1.3	1.4	0.9	1.2	1.6	1.2	0.1	1.6	0.5	-0.0	0.2
Blood Red Count	1.2	11.4	25.9	-3.7	-3.3	-1.2	-3.8	-1.4	-3.4	3.4	-2.7	-5.1	-3.6	-3.6
Hearing difficulty/problems: Yes	1.2	1.9	5.6	0.8	1.5	0.5	1.7	1.7	2.4	0.9	1.2	-1.0	-1.2	-1.1
Angina	1.2	1.6	4.1	1.3	1.0	0.6	-1.2	-1.6	0.4	0.6	0.7	-1.0	-2.0	-2.0
Medication: Metformin	1.2	1.7	3.9	1.2	1.5	1.3	0.8	0.7	1.3	0.3	0.8	-1.4	-2.0	-1.9
Taking other prescription medications	1.2	1.8	3.6	1.0	1.4	1.3	0.5	1.5	0.4	1.1	1.5	-1.9	-1.7	-1.6
Medication: Levothyroxine sodium	1.2	2.1	5.0	0.9	0.5	0.7	-0.2	0.8	0.1	2.1	1.4	-2.2	-2.2	-2.2
Waist circumference	1.2	4.4	8.7	2.5	2.9	1.9	2.5	2.6	2.9	0.8	2.5	-0.5	-0.8	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.7	10.6	1.9	2.5	0.4	3.2	3.1	1.8	-1.1	2.1	0.5	0.6	0.7
Blood clot in the leg (DVT)	1.2	1.6	4.2	1.4	0.9	1.9	0.6	-1.0	2.0	-1.1	1.3	1.7	0.5	0.4
Leg fat percentage (right)	1.2	4.4	9.4	2.6	2.8	2.4	2.3	2.5	3.1	0.5	2.3	-0.2	-0.5	-0.5
Pulse wave peak to peak time	1.2	1.4	3.6	-0.6	-0.0	0.0	1.9	1.5	-0.2	-1.2	-0.3	1.2	1.6	1.8
Health satisfaction	1.2	1.6	4.0	1.8	1.4	2.0	0.4	1.0	0.4	0.8	1.1	-1.1	-1.5	-1.3
Migraine (self-reported)	1.2	1.5	4.2	-0.0	-0.3	0.1	1.5	0.6	-0.6	-1.3	-0.2	1.9	2.1	2.0
Medication: Allopurinol	1.2	1.5	4.1	1.3	1.6	0.2	1.4	1.5	2.0	0.1	1.4	1.0	0.7	0.8
Irritability	1.2	2.0	5.0	0.9	0.8	0.8	1.1	1.5	0.8	-0.0	1.2	-2.2	-2.2	-2.1
Pain experienced in last month	1.2	2.1	4.3	-2.1	-1.4	-1.9	-1.4	-2.0	-0.6	-0.0	-1.3	1.4	1.2	1.1
Ovarian Cancer	1.1	1.5	4.5	-0.4	-0.6	0.4	-1.1	-1.7	-0.1	-1.3	-0.6	2.1	1.6	1.4
Age at First Birth	1.1	1.6	10.1	-0.6	-0.6	-0.3	-2.0	-3.2	-0.9	-0.9	-0.8	0.1	-0.6	-0.6
Type 2 Diabetes (T2D) (2012)	1.1	1.2	3.6	-1.2	-1.4	-1.1	-0.8	-1.1	-1.9	0.5	-1.4	0.4	-0.0	1.0
Ever used hormone-replacement therapy (HRT)	1.1	1.4	7.9	-0.7	-0.8	-1.0	-2.0	-2.8	-0.3	-0.1	-1.2	0.0	-0.2	-0.4
Ever unenthusiastic/disinterested for a whole week	1.1	1.4	3.3	1.8	1.2	1.1	0.8	1.4	0.9	1.4	1.4	-0.5	-1.0	-1.0
Diabetes (self-reported)	1.1	1.8	6.5	0.5	1.2	0.4	-0.3	0.3	0.4	0.5	0.4	-2.0	-2.5	-2.5
Arm fat percentage (right)	1.1	4.3	8.7	2.6	2.9	1.6	2.6	2.7	2.9	0.8	2.1	-0.5	-0.9	-0.8
Pulse wave Arterial Stiffness index	1.1	1.3	3.2	0.5	0.1	-0.0	-1.8	-1.5	0.3	1.1	0.3	-1.2	-1.6	-1.8
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	4.8	0.8	0.2	0.3	-0.0	0.1	-0.0	0.4	0.2	-2.2	-2.2	-2.1
Hypothyroidism/myxoedema (self-reported)	1.1	2.2	5.6	1.1	1.1	0.9	-0.2	1.1	0.7	2.4	1.9	-1.6	-1.9	-2.0
Age at first live birth	1.1	1.9	5.8	0.2	0.4	0.1	0.8	-0.3	0.4	-1.8	-0.1	2.4	2.3	2.3
Age at last live birth	1.1	1.6	5.3	-0.1	-0.2	-0.8	0.2	-0.2	0.1	-1.0	-0.2	2.2	2.3	2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	3.5	0.6	1.0	0.0	0.9	1.8	0.3	1.1	0.8	-1.9	-1.3	-1.2
Medication for cholesterol	1.1	1.6	5.6	-0.5	-0.3	-0.7	-2.0	-1.2	-0.3	2.4	0.0	-1.0	-1.5	-1.6
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	3.2	1.0	0.8	1.8	1.5	1.1	0.6	-1.0	1.2	-1.3	-1.0	-0.9
Bipolar Disorder (2018)	1.0	1.6	3.1	1.6	1.8	1.1	1.7	1.0	1.7	-0.5	1.1	1.1	0.8	0.9
Fed-up feelings	1.0	1.8	3.4	1.6	1.8	1.5	1.3	1.8	0.9	0.8	1.8	-0.5	-1.0	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	1.0	2.3	7.2	-2.7	-2.2	-1.2	-1.4	-0.2	-2.1	-0.2	-1.8	-1.5	-0.4	-0.5
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	3.6	1.7	1.9	1.0	0.4	-0.2	1.0	-0.2	1.4	0.6	-0.5	-0.5
Trunk fat mass	1.0	4.5	9.9	2.5	3.1	1.8	2.6	2.6	3.0	0.8	2.2	-0.4	-0.9	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.4	6.2	-1.8	-1.3	-1.3	-1.8	-0.2	-1.6	1.2	-1.5	-2.5	-1.4	-1.5
Financial difficulties in last 2 years	1.0	1.3	3.4	1.1	0.9	1.2	1.8	1.8	1.2	-0.5	1.1	0.5	0.7	0.8
Heart attack	1.0	1.2	3.6	-0.2	-0.9	-0.0	-1.0	-1.0	-1.7	-0.1	-1.3	-1.9	-1.1	-1.1
Medication: Simvastatin	1.0	1.4	3.8	1.8	1.9	1.3	0.7	0.5	1.5	-0.7	1.6	0.3	-0.6	-0.5
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	3.4	1.6	1.8	0.1	0.2	0.3	1.2	1.0	1.2	0.1	-0.9	-1.0
Prospective memory result	1.0	1.3	4.1	1.6	1.3	2.0	0.3	0.2	1.2	-1.6	1.2	0.4	-0.2	-0.1
Illnesses of mother	1.0	1.3	3.7	-0.9	-1.1	0.5	-0.2	-0.1	-1.3	0.4	-0.3	-1.9	-1.6	-1.8
Forced vital capacity (FVC), Best measure	1.0	3.8	11.0	1.7	2.1	0.0	3.3	2.6	1.6	-1.7	1.9	1.6	1.5	1.6
Neck or shoulder pain in last month	1.0	1.4	3.5	0.8	0.2	1.6	-0.8	-0.0	-0.8	0.7	0.4	-1.8	-1.8	-1.9
Medication: Ibuprofen	1.0	1.3	3.0	0.5	1.0	1.3	1.0	-0.2	1.0	-1.3	0.6	1.7	1.4	1.3
Whole body fat mass	1.0	4.1	8.5	2.2	2.9	1.9	2.7	2.6	2.8	0.7	2.0	-0.4	-0.8	-0.8
Illnesses of father: Heart disease	1.0	1.4	3.6	-1.6	-1.8	-0.9	-0.4	-1.5	-1.2	-1.1	-1.9	-0.1	0.5	0.4
Arm fat percentage (left)	1.0	4.0	8.5	2.4	2.9	1.3	2.4	2.7	2.8	1.1	2.0	-0.6	-0.9	-0.8
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	3.5	1.1	0.6	1.5	0.3	-1.3	1.9	-0.9	1.0	1.8	0.6	0.5
Bipolar Disorder or Schizophrenia	0.9	2.1	5.1	2.3	2.2	0.8	0.2	0.7	0.9	1.7	1.7	-0.9	-1.6	-1.5
Reaction Time	0.9	1.8	4.8	1.3	1.4	1.5	0.2	0.2	0.7	0.2	1.0	-1.6	-2.2	-2.2
Ulcerative Colitis	0.9	1.3	4.8	-0.5	-0.4	-0.6	-0.4	0.4	-1.2	0.9	-0.5	-2.2	-1.8	-1.7
Hypothyroidism (self reported)	0.9	2.1	8.5	0.6	0.5	-0.5	-0.8	1.0	0.4	2.9	1.6	-1.6	-1.9	-1.9
Alcohol usually taken with meals	0.9	1.5	6.7	-1.0	-0.7	-1.0	-1.6	-2.6	-0.9	-1.0	-1.0	1.1	0.5	0.3
Allergy	0.9	2.1	7.5	-2.7	-2.2	-1.7	-1.1	-0.9	-1.4	-0.1	-1.7	0.0	0.8	0.7
Time employed in main current job	0.9	1.0	2.6	0.0	0.5	0.3	-1.6	-1.6	1.1	0.5	1.1	0.2	-1.2	-1.3
Noisy workplace	0.9	1.1	2.6	0.7	0.6	0.8	1.3	1.5	0.7	-0.2	0.4	1.2	1.6	1.6
Birth weight of first child	0.9	1.5	6.3	-0.3	-0.3	-1.5	-0.6	-0.4	-1.1	2.5	-0.1	-1.5	-1.5	-1.5
Pulse wave reflection index	0.9	1.1	3.7	1.7	1.1	1.2	0.2	-0.6	1.9	0.3	1.1	0.4	-0.3	-0.5
Shortness of breath walking on level ground	0.9	1.0	2.7	0.6	0.6	1.2	-1.0	-0.2	-0.8	0.1	0.3	-1.5	-1.6	-1.6
Leg fat mass (right)	0.9	3.5	6.9	1.9	2.5	2.0	2.4	2.6	2.5	0.7	1.9	-0.6	-0.8	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	2.2	0.7	1.2	0.5	1.4	1.5	1.4	0.1	1.5	-0.3	-0.1	-0.0
Back pain experienced in last month	0.9	1.3	3.4	1.0	0.5	1.6	-0.2	-0.6	0.9	0.2	0.7	-1.4	-1.7	-1.8
Mineral and other dietary supplements	0.9	1.3	4.7	0.7	0.9	1.3	1.1	2.2	0.9	0.8	1.3	-1.0	-0.7	-0.7
Hearing aid user	0.9	1.0	3.9	1.1	0.7	0.6	0.9	0.3	2.0	-1.1	0.1	0.9	0.9	1.0
Medication: Blood pressure	0.9	1.6	5.2	0.5	0.1	0.4	1.5	-0.0	0.5	-2.3	-0.1	1.7	1.9	1.8
Medication: Lisinopril	0.9	1.1	5.1	0.6	0.8	0.8	-0.3	-1.6	-0.4	-2.3	0.4	1.4	0.4	0.4
Leg fat percentage (left)	0.9	3.1	7.1	2.5	2.5	2.0	1.6	1.8	2.7	0.8	1.9	-0.2	-0.7	-0.6
Basal cell carcinoma (self-reported)	0.9	1.0	2.6	1.3	1.2	1.3	0.7	0.8	0.8	-0.4	1.6	-0.1	-1.0	-0.9
Heart attack/myocardial infarction (self-reported)	0.9	1.2	2.9	-0.3	-1.0	0.1	-1.0	-1.1	-1.7	-0.3	-1.5	-1.7	-0.9	-0.9
Irritable Bowel Disease (IBD)	0.8	1.9	6.2	-0.8	-0.5	-0.9	0.1	1.3	-1.7	1.5	-0.6	-2.5	-1.8	-1.6
Ulcerative Colitis (UC)	0.8	1.5	4.7	-0.5	-0.3	-0.7	0.2	1.5	-1.2	1.5	-0.5	-2.2	-1.6	-1.4
Allergy or Eczema	0.8	2.1	4.0	2.0	1.6	0.9	1.7	0.7	1.9	-0.8	1.2	1.9	1.1	1.2
Type 2 Diabetes (T2D) (2018)	0.8	1.5	4.8	0.3	0.5	-0.3	-0.6	0.1	-0.4	1.2	0.2	-2.1	-2.2	-2.1
Pack years adult smoking proportion	0.8	1.2	4.0	0.2	0.3	1.4	-0.0	-0.0	-0.3	0.2	0.5	-2.0	-1.9	-2.0
Father’s age at death	0.8	1.1	2.4	0.9	1.5	0.5	-0.3	-0.1	0.7	1.2	1.4	-0.5	-1.4	-1.4
Hair/balding pattern: Pattern 3	0.8	1.3	2.7	0.8	1.3	1.2	0.4	1.6	1.0	1.4	1.3	-0.9	-1.0	-0.9
Ever highly irritable/argumentative for 2 days	0.8	0.9	2.2	1.3	1.2	0.3	1.0	1.4	1.0	0.9	1.5	0.1	-0.1	-0.0
Medication: Paracetamol	0.8	1.3	3.9	0.8	1.3	1.0	0.9	0.2	1.5	-1.0	1.4	2.0	0.9	0.9
High blood pressure (siblings)	0.8	1.1	3.3	0.3	0.3	0.2	0.7	-0.2	0.6	-1.4	-0.1	1.8	1.7	1.7
Medication: Omeprazole	0.8	0.9	2.7	0.7	0.5	1.6	1.1	0.8	0.4	-0.5	0.9	-1.3	-1.0	-1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	1.0	2.9	0.9	1.3	0.7	0.9	1.7	1.3	0.5	1.1	-0.3	-0.7	-0.7
Pulse rate, automated reading	0.8	2.6	5.0	-2.2	-2.1	-1.3	-0.5	-0.3	-2.0	-1.2	-1.9	1.0	1.9	1.8
Suffer from ‘nerves’	0.8	1.3	5.2	0.0	-0.1	0.2	0.8	1.7	-0.5	0.1	0.0	-2.3	-1.6	-1.5
Illnesses of father: None of the above (group 1)	0.8	1.0	3.4	-0.9	-0.3	-0.6	-1.8	-1.3	-0.3	1.7	-0.7	-0.4	-0.6	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	5.9	1.8	2.4	0.3	1.2	1.9	1.3	0.9	1.5	-0.5	-0.4	-0.4
Medication: Bendroflumethiazide	0.8	1.2	3.6	1.1	0.8	0.5	1.3	0.6	0.2	-1.9	0.1	1.4	1.3	1.4
Fractured/broken bones in last 5 years	0.8	1.1	2.7	1.1	1.1	0.5	1.7	1.0	1.6	0.5	1.2	0.8	0.4	0.4
Myopia	0.8	1.1	3.2	-0.6	-0.9	-0.8	-1.2	-1.8	-0.6	-0.8	-0.9	0.9	1.3	1.2
Heart disease (siblings)	0.8	1.0	3.2	-0.9	-0.6	-0.3	-0.4	-0.1	-0.5	1.3	-0.9	-1.8	-1.5	-1.4
Leg fat mass (left)	0.8	3.1	5.7	1.9	2.4	2.0	2.0	2.3	2.3	0.9	1.8	-0.7	-1.0	-0.9
Triglycerides	0.7	1.1	3.1	-1.5	-1.4	-1.3	-0.7	-0.8	-1.8	0.2	-1.0	0.3	0.6	0.7
Lung FEV1/FVC ratio	0.7	3.6	8.4	1.2	1.8	1.7	0.2	1.4	0.9	2.3	0.7	-2.6	-2.9	-2.8
Diabetes (father)	0.7	0.8	3.6	-0.4	-0.1	0.3	0.1	1.7	-0.4	0.1	0.2	-1.9	-1.2	-1.0
Hayfever, allergic rhinitis or eczema	0.7	1.6	4.5	2.1	2.0	0.7	1.3	1.1	1.6	0.0	1.5	0.4	-0.2	-0.0
Stomach or abdominal pain in last month	0.7	0.9	1.8	0.8	1.0	1.3	0.9	1.3	0.8	0.7	1.2	-0.7	-0.7	-0.7
Number of incorrect matches in round	0.7	1.1	3.6	-1.0	-1.3	-0.4	-1.7	-1.9	-1.1	-0.4	-1.2	0.5	0.2	0.1
Medication: Ramipril	0.7	0.9	2.1	0.3	1.1	1.1	1.2	1.4	0.5	0.8	1.0	-1.0	-0.9	-0.8
Alcohol intake versus 10 years previously	0.7	1.0	2.9	0.8	0.2	1.2	0.1	0.5	-0.5	0.4	0.5	-1.5	-1.7	-1.7
Arm fat mass (right)	0.7	3.0	6.3	1.9	2.5	1.4	2.3	2.5	2.3	0.9	1.6	-0.6	-0.7	-0.6
Loud music exposure frequency	0.7	0.8	2.6	0.4	0.1	0.8	1.6	0.7	0.9	-1.5	0.3	0.5	0.6	0.6
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	2.1	-0.9	-0.8	-1.4	0.7	0.1	-0.4	-1.4	-1.2	0.9	1.4	1.4
Number of children fathered	0.7	0.8	2.1	0.8	0.5	1.1	0.5	0.3	0.7	-0.6	0.2	1.4	1.3	1.3
Eye problems/disorders: None of the above	0.7	0.8	2.0	-1.4	-1.2	-0.7	-1.1	-1.0	-1.4	0.0	-0.9	0.1	0.3	0.2
Heart disease (mother)	0.7	0.9	2.6	1.5	1.6	-0.0	-1.1	-0.6	1.0	0.7	0.8	0.1	-0.7	-0.7
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.3	0.0	0.2	-0.7	-0.8	-0.4	0.9	0.4	0.1	1.5	1.5	1.4
Osteoporosis (self-reported)	0.7	0.9	2.2	0.9	0.6	1.2	1.5	1.0	0.2	-1.5	1.1	0.5	0.2	0.3
Medication: Gliclazide	0.7	0.8	2.2	0.5	1.0	0.7	-0.2	-0.2	0.8	0.6	0.6	-1.0	-1.5	-1.5
Average weekly champagne plus white wine intake	0.7	1.0	2.6	-0.6	-0.2	0.1	1.6	1.2	0.5	-0.9	-0.3	0.7	1.4	1.6
Medication: Paracetamol	0.7	1.0	3.5	0.6	0.9	0.9	0.4	-0.3	1.4	-0.8	1.1	1.9	0.9	0.8
Supplements: Calcium	0.7	0.7	2.7	-0.4	-0.3	-0.4	-1.2	-1.6	-1.4	-0.6	-0.9	-0.1	-0.3	-0.4
Pack years of smoking	0.7	1.0	3.2	0.2	0.3	1.1	-0.1	-0.3	-0.4	0.1	0.4	-1.8	-1.7	-1.8
LDL Cholesterol	0.6	0.9	4.5	-0.6	-1.1	-0.1	-1.1	-0.9	-2.1	0.4	-1.2	-0.7	-0.2	-0.1
BMI	0.6	3.2	8.0	1.9	2.6	1.3	2.1	2.8	2.5	0.9	1.8	-0.6	-0.6	-0.5
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	1.8	1.1	1.0	1.4	-0.6	0.0	0.6	0.2	1.0	0.0	-0.7	-0.6
Medication: Co-codamol	0.6	0.7	2.6	0.2	0.1	0.4	1.5	0.6	0.0	-1.6	0.2	0.8	0.9	0.9
Body mass index (BMI)	0.6	2.8	5.7	1.9	2.3	1.4	1.9	2.4	2.3	1.2	1.6	-0.6	-0.7	-0.6
Nervous feelings	0.6	1.1	3.3	0.2	0.5	-0.1	0.0	1.1	-0.1	1.1	0.8	-1.7	-1.8	-1.7
Lung cancer (father)	0.6	0.7	3.8	0.5	1.1	0.5	1.0	0.3	1.9	-0.2	0.9	0.6	0.1	0.2
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.2	1.2	0.5	0.7	0.3	1.2	0.3	0.2	0.3	-1.5	-1.0	-0.9
Number of full brothers	0.6	0.7	2.7	-0.1	-0.2	-0.8	-1.6	-1.0	-0.3	1.1	-0.5	-0.3	-1.0	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	3.5	-1.9	-1.1	-0.9	1.1	1.1	-1.4	-1.0	-1.2	-0.0	1.0	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.8	1.3	1.2	0.7	-0.3	0.4	0.9	1.0	1.3	0.9	-0.0	-0.1
Arm fat mass (left)	0.6	2.5	5.6	1.7	2.3	1.2	2.2	2.4	2.0	0.9	1.4	-0.5	-0.7	-0.6
Commuting to job workplace: Cycle	0.6	0.7	1.5	0.6	0.7	1.0	-0.9	-0.1	-0.0	1.2	0.5	-0.7	-1.2	-1.2
Alzheimer’s Disease (in mother)	0.5	0.6	2.3	1.5	1.0	0.3	0.2	0.5	0.9	-0.2	0.8	0.9	0.6	0.7
Lupus	0.5	0.7	3.3	0.7	0.4	0.4	1.8	1.4	0.8	-0.5	0.6	0.1	0.4	0.5
Smoking Status	0.5	1.2	2.7	1.1	1.1	1.3	1.6	1.3	1.6	-0.4	1.1	0.5	0.2	0.3
Average weekly spirits intake	0.5	0.7	1.9	1.3	0.7	0.8	0.5	-0.3	1.1	-1.4	0.4	-0.2	-0.7	-0.7
Severe depression (siblings)	0.5	0.6	3.3	0.9	0.3	-0.3	-0.2	0.2	0.7	1.8	0.3	-0.9	-0.6	-0.7
Mouth/teeth dental problems	0.5	0.8	3.3	0.1	1.1	-0.4	1.0	1.8	0.9	1.1	1.1	-0.2	-0.2	-0.1
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	1.8	-1.0	-1.0	-1.3	-0.4	-0.4	-0.4	-0.4	-1.3	0.2	0.8	0.8
Weight	0.5	2.3	6.0	1.3	2.0	1.3	2.4	2.5	1.9	0.5	1.3	-0.2	-0.1	0.0
Birth weight	0.5	1.0	3.9	0.8	1.3	0.5	-0.6	-0.0	0.6	1.4	2.0	0.3	-1.0	-1.0
Qualifications: College or University degree	0.5	1.7	4.7	-0.2	-0.2	-0.6	1.3	-0.1	0.4	-1.8	-0.6	1.8	2.1	2.2
Mean time to correctly identify matches	0.5	1.0	2.9	0.7	1.1	0.7	-0.7	-0.9	0.3	0.6	0.2	-1.2	-1.7	-1.7
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.1	1.2	1.4	0.3	0.4	-0.1	0.8	0.3	0.8	0.9	0.3	0.3
Wears glasses or contact lenses	0.5	0.6	1.5	-0.5	-1.0	0.3	-1.1	-0.8	-1.2	-0.2	-1.2	-0.4	0.1	0.1
Alzheimer’s Disease (in father)	0.4	0.4	1.1	0.3	0.1	-1.1	0.2	0.2	0.5	-1.0	0.0	0.6	0.8	1.0
Breast Cancer	0.4	0.9	2.1	-0.7	-0.6	-1.5	0.2	-0.6	-0.8	-0.8	-0.5	1.4	1.1	1.0
Fasting Glucose	0.4	0.5	1.6	0.0	0.1	1.3	0.0	-0.1	-0.7	-0.6	0.6	-0.6	-1.0	-1.2
HbA1C	0.4	0.4	2.0	0.4	0.0	1.4	0.5	0.6	-0.6	0.5	0.5	0.4	0.6	0.6
Heel T-Score	0.4	3.1	11.5	-1.1	-0.1	-2.0	-1.6	-1.0	0.5	3.4	0.0	-2.0	-2.2	-2.2
Relative age of first facial hair	0.4	0.9	2.8	1.1	0.7	-1.0	-0.3	-0.9	1.4	0.1	0.8	1.7	0.7	0.7
Impedance of leg (right)	0.4	1.8	5.4	1.4	0.9	1.8	1.3	0.4	1.4	-2.3	1.6	1.2	0.6	0.6
Qualifications: CSEs or equivalent	0.4	0.5	2.2	1.1	0.7	-0.0	0.2	0.7	0.9	0.6	1.5	0.1	0.0	-0.1
Number of live births	0.4	0.6	1.4	0.9	0.5	-0.4	-1.0	-1.0	0.9	0.8	0.7	1.2	0.1	-0.0
Qualifications: A levels/AS levels or equivalent	0.4	1.0	4.0	-0.8	-0.5	-1.0	0.3	-0.8	-0.3	-2.0	-0.8	0.7	1.1	1.2
Mouth/teeth dental problems: Loose teeth	0.4	0.4	3.2	-0.2	-0.7	-0.1	-0.7	0.3	-0.4	1.8	-0.2	-0.5	-0.1	-0.2
Medication: Seretide 50 evohaler	0.4	0.4	1.0	0.7	1.0	0.4	-0.3	-0.8	0.6	0.8	0.5	-0.0	-0.6	-0.7
Smoking status: Current	0.4	0.7	1.8	0.6	0.5	1.2	1.3	1.3	0.7	-0.2	0.5	0.6	0.8	0.8
Number of operations (self-reported)	0.4	0.6	1.7	1.1	0.4	1.3	-0.0	-1.2	0.4	-1.2	0.1	0.8	0.5	0.3
Alzheimer’s Disease (including proxy)	0.3	0.4	1.3	1.1	0.7	-0.7	-0.2	0.4	0.5	0.0	0.7	0.6	0.8	0.7
Crohns Disease (2017)	0.3	0.6	2.0	-0.4	-0.2	-0.3	0.0	0.6	-1.2	0.7	-0.1	-1.4	-1.1	-1.0
Mean Putamen Volume	0.3	0.3	1.4	-0.7	-0.6	-1.2	-0.4	-0.1	-0.6	0.3	-0.6	-0.2	0.0	-0.1
HDL Cholesterol	0.3	0.4	1.9	0.1	-0.1	0.2	-0.6	-0.4	-0.3	0.4	-0.5	-1.4	-0.7	-1.2
Rheumatoid Arthritis	0.3	0.4	1.0	0.8	0.8	0.4	-0.2	-0.5	0.4	0.7	1.0	0.4	-0.3	-0.4
Chronotype (morning person)	0.3	0.8	3.2	-0.7	-0.4	0.7	1.4	0.5	-0.7	-1.8	-0.4	0.3	0.9	0.8
Hair Pigment	0.3	9.4	21.5	-2.1	-2.4	-1.6	-4.6	-2.9	-2.7	3.5	-2.0	-3.5	-3.5	-3.7
Ever had hysterectomy (womb removed)	0.3	0.3	1.2	1.0	0.7	0.5	0.4	0.4	1.1	0.2	0.1	-0.5	-0.2	-0.2
Medication for hormone replacement therapy	0.3	0.3	0.8	-0.7	-0.5	-0.4	0.1	0.2	-0.8	-0.9	-0.8	-0.3	0.4	0.4
Current tobacco smoking	0.3	0.6	1.5	0.8	0.5	1.2	1.0	1.2	0.7	-0.1	0.5	0.4	0.5	0.5
Maternal smoking around birth	0.3	0.4	1.4	0.5	0.1	-1.0	0.7	0.3	0.6	-1.2	-0.1	0.2	0.8	0.8
Had other major operations	0.3	0.4	1.2	0.7	0.0	1.1	0.9	0.7	0.4	-0.6	-0.1	0.1	0.6	0.5
Hip circumference	0.3	1.5	5.1	0.8	1.6	1.2	2.3	1.8	1.5	0.1	0.8	-0.3	-0.3	-0.2
Asthma	0.3	0.6	1.4	1.1	0.5	0.8	-0.5	-0.6	-0.5	0.1	-0.2	-1.0	-1.2	-1.1
Leg pain on walking	0.3	0.4	1.3	-0.5	-1.1	0.6	-0.3	-0.4	-1.0	0.4	-0.9	-0.3	0.1	-0.0
Knee pain experienced in last month	0.3	0.4	1.9	0.6	0.7	0.7	0.1	0.5	0.4	1.4	0.2	-0.7	-0.4	-0.5
Smoking status: Previous	0.3	0.5	1.4	0.3	0.5	-0.4	-0.4	-0.5	0.8	0.6	0.4	-0.5	-1.2	-1.1
Eye problems/disorders: Cataract	0.3	0.3	1.0	1.0	0.3	-0.3	0.1	0.2	0.3	0.8	0.0	-0.8	-0.6	-0.6
Breast cancer (self-reported)	0.3	0.4	1.1	0.1	-0.1	0.7	0.7	0.6	0.2	-0.4	0.4	0.8	0.9	1.0
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.3	-0.6	-0.4	-0.6	0.5	0.9	0.0	1.2	0.2	-0.1	0.1	0.1
Medication: Atorvastatin	0.3	0.4	1.4	0.5	0.5	-1.2	0.9	0.9	0.5	0.6	0.1	-0.2	0.1	0.1
Alcohol drinker status: Never	0.3	0.4	1.7	-1.3	-0.9	0.5	-0.4	0.2	-0.8	-0.4	-0.4	-0.6	-0.2	-0.2
Ever smoked	0.3	0.5	1.7	1.0	1.1	0.6	0.5	0.2	1.3	0.1	0.5	0.6	-0.1	-0.0
Cholesterol lowering medication	0.3	0.4	1.4	0.4	0.1	-0.4	0.7	0.1	0.7	-1.2	-0.0	0.5	0.7	0.7
Alcohol drinker status: Previous	0.3	0.4	1.3	-0.2	-0.3	-0.4	0.5	-0.1	-0.3	0.5	0.1	1.1	1.1	1.0
Verbal and Numeric Reasoning (VNR)	0.2	0.4	1.3	-0.8	-1.1	0.1	-0.2	0.0	-1.1	0.1	-0.9	-0.8	0.0	0.1
Body Mass Index (BMI) (2010)	0.2	0.3	1.6	0.2	0.4	0.7	-0.3	0.1	0.0	1.3	0.3	-0.6	-0.5	-0.6
Crohns Disease (2012)	0.2	0.4	0.9	-0.3	-0.3	-1.0	0.5	0.9	-0.9	0.9	-0.1	-0.2	0.2	0.3
Primary Biliary Cirrhosis	0.2	0.3	1.1	0.1	-0.3	1.0	-0.1	-0.0	-0.7	-0.1	0.1	-0.9	-0.7	-0.7
Respiratory disease	0.2	0.4	1.4	1.2	0.5	0.4	0.1	0.2	-0.4	-0.0	0.3	-0.8	-1.0	-1.0
Tanning	0.2	2.4	7.0	1.5	0.7	1.2	2.6	2.3	2.0	-0.4	2.2	0.4	-0.0	0.1
Diabetes (mother)	0.2	0.2	1.3	-0.3	-0.3	-0.1	0.2	0.5	-1.1	-0.5	-0.6	0.0	0.3	0.4
Medication: Atenolol	0.2	0.2	0.8	0.1	-0.2	0.3	0.9	0.0	0.2	-0.5	-0.5	0.7	0.4	0.4
Impedance of leg (left)	0.2	0.9	3.4	1.2	0.5	1.3	0.4	-0.4	0.9	-1.8	1.0	1.1	0.3	0.3
Past tobacco smoking	0.2	0.3	1.5	-0.5	-0.8	0.2	-0.1	0.2	-1.2	-0.6	-0.5	-0.2	0.6	0.5
Pain all over the body in last month	0.2	0.3	1.1	0.5	0.3	0.6	-1.0	-0.6	-0.4	0.0	-0.1	0.0	-0.4	-0.5
Fluid intelligence score	0.2	0.4	1.2	-0.9	-1.1	-0.0	0.2	0.0	-1.1	-0.4	-0.7	-0.5	0.1	0.2
Illnesses of siblings	0.2	0.2	0.8	-0.1	-0.1	-0.1	-0.9	-0.8	-0.4	0.5	0.0	-0.3	-0.5	-0.5
Exposure to tobacco smoke outside home	0.2	0.2	0.9	0.3	-0.1	-0.2	-0.2	0.0	0.2	0.3	-0.1	0.6	1.0	0.9
Alcohol intake frequency.	0.2	0.4	1.4	-0.0	-0.0	0.7	0.1	0.9	-1.1	-0.2	-0.2	-1.2	-0.5	-0.5
Commuting to job workplace: Walk	0.2	0.3	1.0	0.3	0.3	0.9	-0.1	-0.5	0.6	-1.0	0.4	0.2	0.1	0.2
Asthma (self-reported)	0.2	0.5	1.4	1.2	0.6	1.0	-0.2	-0.5	-0.2	-0.5	-0.1	-0.6	-0.8	-0.8
Mother’s age at death	0.2	0.3	1.5	-0.0	0.4	-0.5	-0.2	-1.2	0.3	0.1	0.3	0.9	0.0	0.0
Supplements: Fish oil (including cod liver oil)	0.2	0.2	1.1	0.7	0.4	-0.3	-0.2	-1.1	0.4	0.0	0.1	0.7	0.1	0.1
Prostate Cancer	0.1	0.1	0.4	0.6	-0.1	-0.2	0.0	0.1	0.2	-0.5	0.0	0.3	0.6	0.6
Coronary Artery Disease (CAD)	0.1	0.1	0.6	-0.8	-0.2	-0.5	0.3	-0.1	-0.5	0.4	0.0	-0.3	-0.0	-0.0
Blood Eosinophil Count	0.1	0.9	2.9	1.0	1.0	1.2	1.1	0.7	1.7	0.6	1.2	0.3	0.2	0.2
Height	0.1	1.7	4.0	-0.7	0.1	-0.3	2.0	0.4	-0.6	-1.6	-0.4	1.8	1.9	2.0
Leg fat-free mass (left)	0.1	0.8	3.7	-0.2	0.8	0.1	1.7	1.9	0.5	0.7	0.2	-0.4	0.1	0.1
Relative age voice broke	0.1	0.2	1.3	0.1	0.3	-0.1	-0.1	-0.4	0.1	-1.1	0.3	0.3	-0.1	-0.0
Age when periods started (menarche)	0.1	0.3	0.7	-0.2	-0.9	0.1	-0.7	-0.5	-0.6	0.2	-0.4	-0.6	-0.6	-0.7
Sitting height	0.1	0.7	3.7	-0.3	0.2	0.0	1.9	1.2	0.2	-0.8	0.5	0.5	0.6	0.7
Leg predicted mass (left)	0.1	0.8	3.8	-0.3	0.7	0.0	1.8	1.9	0.5	0.6	0.1	-0.4	0.2	0.2
Impedance of arm (right)	0.1	0.7	1.6	1.2	1.0	0.3	1.1	0.8	0.9	-1.0	1.0	0.2	-0.1	-0.0
Trunk fat-free mass	0.1	0.6	1.5	-0.6	-0.0	0.1	1.1	1.1	-0.3	0.0	-0.4	0.5	1.1	1.2
Impedance of arm (left)	0.1	0.6	1.2	1.1	1.1	0.1	1.0	0.6	1.0	-0.9	1.0	0.5	0.0	0.1
Trunk predicted mass	0.1	0.5	1.3	-0.6	0.0	0.1	1.1	1.1	-0.3	0.1	-0.3	0.5	1.1	1.1
Standing height	0.1	1.1	3.7	-0.7	0.2	0.2	1.9	1.0	0.0	-1.6	0.0	1.1	1.3	1.4
Arm fat-free mass (right)	0.1	0.5	0.9	-0.9	-0.2	-0.4	0.8	0.7	-0.4	0.4	-0.7	0.5	0.9	0.9
Comparative body size at age 10	0.1	0.4	2.4	-0.6	0.0	-0.8	-0.4	0.7	0.2	1.6	-0.2	-0.4	-0.0	0.0
Arm predicted mass (right)	0.1	0.4	0.9	-0.9	-0.2	-0.1	0.9	0.8	-0.2	0.4	-0.6	0.4	0.8	0.9
Comparative height size at age 10	0.1	0.6	3.5	-1.9	-0.7	-0.8	0.5	0.1	-0.6	0.0	-1.0	0.1	0.6	0.6
Illnesses of siblings: Diabetes	0.1	0.1	0.5	-0.2	-0.0	0.0	0.5	0.7	-0.3	-0.7	-0.1	-0.3	0.1	0.1
Whole body fat-free mass	0.1	0.5	1.7	-0.6	0.2	0.0	1.3	1.2	-0.1	0.3	-0.2	0.2	0.8	0.9
Leg fat-free mass (right)	0.1	0.5	2.0	-0.5	0.5	-0.3	1.2	1.4	0.1	1.0	-0.2	-0.4	0.1	0.1
Whole body water mass	0.1	0.5	1.9	-0.6	0.2	-0.0	1.4	1.3	-0.0	0.2	-0.3	0.2	0.8	0.9
Leg predicted mass (right)	0.1	0.4	1.7	-0.6	0.3	-0.5	1.0	1.3	-0.0	1.1	-0.3	-0.4	0.1	0.1
Basal metabolic rate	0.1	0.6	2.8	-0.1	0.6	0.3	1.7	1.7	0.4	0.3	0.1	0.1	0.6	0.6
Arm fat-free mass (left)	0.1	0.3	0.9	-0.4	0.1	0.2	1.0	0.9	0.0	0.3	-0.3	0.3	0.7	0.8
Impedance of whole body	0.1	0.7	1.8	1.2	0.9	0.7	0.7	0.2	1.0	-1.3	1.1	0.7	0.1	0.1
Arm predicted mass (left)	0.1	0.4	1.0	-0.7	-0.1	0.2	0.9	0.8	-0.1	0.2	-0.6	0.4	1.0	1.0
Blood White Count	0.0	0.2	1.1	0.1	-0.3	0.4	-0.0	1.1	0.8	0.5	0.4	-0.0	0.1	0.2

Hub : Genes

KIF2A

Models

Trait associations