Best TWAS P=1.1e-08 · Best GWAS P=8.89e-08 conditioned to 0.471
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | NDUFAF6 | 0.28 | 0.13 | lasso | 7 | 0.14 | 5.8e-05 | 5.3 | -5.2 | 2.2e-07 | -0.99 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | NDUFAF6 | 0.07 | 0.03 | enet | 9 | 0.01 | 7.6e-02 | 5.3 | -5.7 | 1.1e-08 | -0.87 | 0.01 | 0.97 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | TP53INP1 | 0.04 | 0.05 | blup | 56 | 0.06 | 4.2e-07 | 5.3 | 5.3 | 1.4e-07 | 0.94 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | TP53INP1 | 0.06 | 0.02 | lasso | 3 | 0.03 | 2.8e-03 | 5.3 | 5.3 | 1.0e-07 | 1.00 | 0.01 | 0.97 | FALSE |