Best TWAS P=3.53e-12 · Best GWAS P=6.28e-19 conditioned to 4.64e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | TDRD1 | 0.06 | 0.02 | bslmm | 509 | 0.02 | 1.4e-03 | -2.7 | -5.2 | 1.5e-07 | 0.29 | 0.75 | 0.01 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ADRB1 | 0.16 | 0.03 | enet | 31 | 0.07 | 4.1e-08 | -8.9 | 7.0 | 3.5e-12 | -0.60 | 0.00 | 0.98 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | C10orf118 | 0.03 | 0.01 | blup | 42 | 0.02 | 1.9e-03 | -2.8 | 5.6 | 2.0e-08 | 0.07 | 0.02 | 0.39 | TRUE |