Best TWAS P=7.26e-12 · Best GWAS P=1.23e-12 conditioned to 0.00283
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | HOXC5 | 0.02 | 0.00 | blup | 51 | 0.01 | 2.4e-02 | -7.0 | -6.0 | 1.6e-09 | 0.76 | 0.01 | 0.73 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HOXC6 | 0.03 | 0.02 | blup | 50 | 0.03 | 3.9e-04 | -7.1 | 6.3 | 3.2e-10 | -0.84 | 0.00 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | HOXC8 | 0.03 | 0.05 | enet | 5 | 0.04 | 2.4e-05 | -7.1 | 6.7 | 1.5e-11 | -0.97 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | FLJ12825 | 0.15 | 0.02 | lasso | 5 | 0.06 | 8.9e-03 | -7.1 | -6.9 | 7.3e-12 | 0.75 | 0.01 | 0.72 | TRUE |