[Hub]/) : Traits : Hypertension (Self-reported) : ← →

chr12:69,057,879-70,476,863

Best TWAS P=1.19e-08 · Best GWAS P=1.79e-06 conditioned to 0.818

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex YEATS4 0.37 0.23 lasso 7 0.45 4.6e-61 -3.3 5.2 2.5e-07 0.75 0.08 0.77 FALSE
2 GTEx Artery Aorta YEATS4 0.25 0.12 enet 11 0.21 5.0e-12 4.4 5.7 1.2e-08 0.86 0.02 0.94 TRUE
3 GTEx Artery Coronary YEATS4 0.34 0.10 lasso 11 0.12 7.0e-05 -2.9 5.3 1.0e-07 0.55 0.05 0.53 FALSE
4 GTEx Artery Tibial YEATS4 0.37 0.23 enet 21 0.35 3.2e-28 -3.3 5.2 2.0e-07 0.59 0.27 0.16 FALSE
5 GTEx Nerve Tibial YEATS4 0.32 0.22 enet 15 0.32 2.6e-23 -3.3 5.2 2.1e-07 0.69 0.27 0.17 FALSE
6 GTEx Prostate YEATS4 0.40 0.01 lasso 6 0.06 1.6e-02 4.4 5.2 1.8e-07 0.79 0.02 0.37 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma YEATS4 0.26 0.18 enet 17 0.29 4.9e-33 -3.5 5.5 4.2e-08 0.69 0.20 0.24 FALSE
8 The Cancer Genome Atlas Pancreatic Adenocarcinoma YEATS4 0.19 0.04 enet 15 0.08 4.2e-04 -3.3 5.2 2.5e-07 0.65 0.02 0.63 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma YEATS4 0.39 0.27 enet 12 0.47 1.2e-50 -3.3 5.2 2.4e-07 0.69 0.21 0.18 FALSE