Best TWAS P=1.1e-16 · Best GWAS P=1.04e-16 conditioned to 0.0385
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PHACTR1 | 0.19 | 0.09 | enet | 25 | 0.12 | 5.7e-07 | 8.3 | -7.9 | 3.4e-15 | -0.86 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Artery Aorta | RP1-257A7.5 | 0.11 | 0.14 | lasso | 3 | 0.13 | 1.7e-07 | 8.3 | -8.0 | 1.5e-15 | -0.95 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Artery Coronary | RP1-257A7.5 | 0.25 | 0.07 | lasso | 5 | 0.09 | 5.5e-04 | -7.1 | -8.3 | 1.1e-16 | -0.88 | 0.00 | 0.99 | TRUE |
| 4 | GTEx | Artery Tibial | PHACTR1 | 0.21 | 0.10 | enet | 59 | 0.13 | 2.1e-10 | 8.3 | -7.7 | 1.1e-14 | -0.73 | 0.00 | 1.00 | FALSE |
| 5 | GTEx | Artery Tibial | RP1-257A7.5 | 0.16 | 0.10 | enet | 14 | 0.11 | 7.6e-09 | -6.4 | -7.8 | 7.5e-15 | -0.81 | 0.01 | 0.99 | FALSE |