Best TWAS P=5.31e-09 · Best GWAS P=4.78e-12 conditioned to 1.3e-08
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | SLC22A3 | 0.10 | 0.02 | blup | 582 | 0.05 | 4.4e-07 | 1.9 | 5.8 | 5.3e-09 | 0.09 | 0.56 | 0.42 | TRUE |
2 | GTEx | Artery Tibial | RP11-288H12.3 | 0.17 | 0.01 | lasso | 8 | 0.06 | 2.3e-05 | 4.5 | 5.7 | 1.0e-08 | 0.14 | 0.23 | 0.06 | TRUE |