48 significantly associated models · 15 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 109098737 | 110517617 | 3 | 1 | 5.4e-09 | 3.9e-09 | 1.0e+00 | 100 | PSRC1 |
2 | 1 | 222096959 | 223567803 | 3 | 1 | 2.4e-12 | 3.5e-12 | 1.0e+00 | 100 | RP11-378J18.8 |
3 | 3 | 135861666 | 137253713 | 1 | 1 | 2.8e-07 | 1.1e-07 | 8.0e-02 | 89 | RP11-731C17.2 |
4 | 6 | 12020241 | 13990267 | 2 | 1 | 1.1e-16 | 1.0e-16 | 3.8e-02 | 94 | RP1-257A7.5 |
5 | 6 | 159820779 | 161571560 | 2 | 2 | 5.3e-09 | 4.8e-12 | 1.3e-08 | 32 | RP11-288H12.3 SLC22A3 |
6 | 9 | 21303958 | 22819407 | 2 | 2 | 7.3e-16 | 6.8e-31 | 8.3e-16 | 52 | CDKN2B CDKN2B-AS1 |
7 | 15 | 90730363 | 92135418 | 1 | 1 | 3.6e-08 | 2.8e-06 | 5.6e-01 | 98 | FES |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Artery Aorta | 3 | 0.101 | 1.4 |
GTEx | Artery Coronary | 1 | 0.085 | 1.4 |
GTEx | Artery Tibial | 4 | 0.106 | 1.4 |
GTEx | Brain Cerebellum | 1 | 0.050 | 1.4 |
GTEx | Brain Putamen basal ganglia | 0 | 0.000 | 1.4 |
GTEx | Lung | 1 | 0.035 | 1.4 |
GTEx | Spleen | 0 | 0.000 | 1.4 |
GTEx | Stomach | 0 | 0.000 | 1.4 |
GTEx | Vagina | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 0 | 0.000 | 1.4 |
GTEx | Adipose Subcutaneous | 1 | 0.029 | 1.3 |
GTEx | Adipose Visceral Omentum | 0 | 0.000 | 1.3 |
GTEx | Adrenal Gland | 0 | 0.000 | 1.3 |
GTEx | Brain Caudate basal ganglia | 0 | 0.000 | 1.3 |
GTEx | Brain Cerebellar Hemisphere | 3 | 0.201 | 1.3 |
GTEx | Brain Cortex | 0 | 0.000 | 1.3 |
GTEx | Brain Frontal Cortex BA9 | 0 | 0.000 | 1.3 |
GTEx | Brain Hypothalamus | 1 | 0.169 | 1.3 |
GTEx | Breast Mammary Tissue | 1 | 0.051 | 1.3 |
GTEx | Breast Mammary Tissue (Male) | 0 | 0.000 | 1.3 |
GTEx | Cells EBV-transformed lymphocytes | 0 | 0.000 | 1.3 |
GTEx | Cells Transformed fibroblasts | 3 | 0.071 | 1.3 |
GTEx | Colon Sigmoid | 1 | 0.068 | 1.3 |
GTEx | Colon Transverse | 0 | 0.000 | 1.3 |
GTEx | Esophagus Gastroesophageal Junction | 1 | 0.069 | 1.3 |
GTEx | Esophagus Mucosa | 1 | 0.030 | 1.3 |
GTEx | Esophagus Muscularis | 2 | 0.062 | 1.3 |
GTEx | Heart Atrial Appendage | 0 | 0.000 | 1.3 |
GTEx | Heart Left Ventricle | 0 | 0.000 | 1.3 |
GTEx | Liver | 1 | 0.139 | 1.3 |
GTEx | Muscle Skeletal | 1 | 0.035 | 1.3 |
GTEx | Nerve Tibial | 2 | 0.046 | 1.3 |
GTEx | Ovary | 1 | 0.110 | 1.3 |
GTEx | Pancreas | 0 | 0.000 | 1.3 |
GTEx | Pituitary | 0 | 0.000 | 1.3 |
GTEx | Prostate | 1 | 0.120 | 1.3 |
GTEx | Skin Not Sun Exposed Suprapubic | 0 | 0.000 | 1.3 |
GTEx | Skin Sun Exposed Lower leg | 2 | 0.055 | 1.3 |
GTEx | Small Intestine Terminal Ileum | 0 | 0.000 | 1.3 |
GTEx | Thyroid | 0 | 0.000 | 1.3 |
GTEx | Uterus | 0 | 0.000 | 1.3 |
GTEx | Whole Blood | 1 | 0.050 | 1.3 |
METSIM | Adipose | 0 | 0.000 | 1.3 |
NTR | Blood | 0 | 0.000 | 1.3 |
ROSMAP | Brain Pre-frontal Cortex | 1 | 0.023 | 1.3 |
CommonMind | Brain Pre-frontal Cortex | 4 | 0.074 | 1.3 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 2 | 0.045 | 1.3 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 1 | 0.024 | 1.3 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 1 | 0.049 | 1.3 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 2 | 0.046 | 1.3 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Thyroid Carcinoma | 1 | 0.019 | 1.3 |
GTEx | Brain Nucleus accumbens basal ganglia | 0 | 0.000 | 1.2 |
GTEx | Breast Mammary Tissue (Female) | 1 | 0.061 | 1.2 |
GTEx | Testis | 0 | 0.000 | 1.2 |
YFS | Blood | 0 | 0.000 | 1.2 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 0 | 0.000 | 1.2 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 0 | 0.000 | 1.2 |
The Cancer Genome Atlas | Esophageal Carcinoma | 0 | 0.000 | 1.2 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 0 | 0.000 | 1.2 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 2 | 0.181 | 1.2 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 0 | 0.000 | 1.2 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 0 | 0.000 | 1.2 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 0 | 0.000 | 1.2 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 0 | 0.000 | 1.2 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.000 | 1.2 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.1 |