Best TWAS P=7.27e-16 · Best GWAS P=6.8e-31 conditioned to 8.35e-16
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | CDKN2B | 0.08 | 0.05 | lasso | 4 | 0.06 | 2.4e-07 | 7.8 | 8.1 | 7.3e-16 | 0.59 | 0.97 | 0.02 | TRUE |
2 | CommonMind | Brain Pre-frontal Cortex | CDKN2B-AS1 | 0.11 | 0.02 | blup | 501 | 0.03 | 1.7e-04 | 7.8 | 7.5 | 5.9e-14 | 0.62 | 0.10 | 0.88 | TRUE |