Best TWAS P=3.58e-08 · Best GWAS P=2.76e-06 conditioned to 0.558
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | FES | 0.28 | 0.17 | enet | 21 | 0.20 | 2.8e-15 | 4.4 | -5.2 | 1.6e-07 | -0.91 | 0.01 | 0.97 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FES | 0.06 | 0.05 | blup | 46 | 0.07 | 7.4e-14 | 4.4 | -5.5 | 3.6e-08 | -0.90 | 0.01 | 0.96 | TRUE |