Best TWAS P=5.54e-10 · Best GWAS P=5.61e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | TSPAN15 | 0.49 | 0.52 | lasso | 3 | 0.52 | 8.0e-40 | -6.2 | -6.2 | 7.0e-10 | 1.00 | 0 | 1 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | TSPAN15 | 0.18 | 0.15 | lasso | 2 | 0.14 | 7.1e-12 | -6.2 | -6.2 | 5.5e-10 | 1.00 | 0 | 1 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | TSPAN15 | 0.05 | 0.04 | lasso | 2 | 0.03 | 8.1e-05 | -6.2 | -5.5 | 4.9e-08 | 0.97 | 0 | 1 | FALSE |