[Hub]/) : Traits : Asthma (self-reported) :

chr4:122,377,715-123,976,639

Best TWAS P=3.61e-17 · Best GWAS P=4.32e-14 conditioned to 0.00757

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KIAA1109 0.09 0.08 bslmm 390 0.08 8.9e-10 7.4 -5.3 1.5e-07 -0.91 0.01 0.99 FALSE
2 GTEx Artery Aorta KIAA1109 0.11 0.00 lasso 7 0.01 5.1e-02 7.6 -7.2 5.3e-13 -0.88 0.02 0.89 FALSE
3 GTEx Artery Tibial KIAA1109 0.16 0.07 lasso 6 0.05 5.1e-05 7.4 -7.0 2.1e-12 -0.97 0.01 0.99 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia KIAA1109 0.22 0.07 lasso 7 0.03 5.9e-02 7.4 -7.2 8.6e-13 -0.97 0.02 0.78 FALSE
5 GTEx Colon Transverse KIAA1109 0.25 -0.01 enet 16 0.00 4.1e-01 7.0 -7.2 4.5e-13 -0.86 0.02 0.72 FALSE
6 ROSMAP Brain Pre-frontal Cortex KIAA1109 0.08 0.08 lasso 7 0.07 2.5e-09 7.4 -7.1 1.1e-12 -0.98 0.01 0.99 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma KIAA1109 0.03 0.03 lasso 1 0.02 1.2e-05 7.4 -7.4 1.1e-13 -0.99 0.00 1.00 FALSE
8 The Cancer Genome Atlas Esophageal Carcinoma KIAA1109 0.32 0.02 blup 45 0.02 7.4e-02 7.0 -8.4 3.6e-17 -0.66 0.01 0.70 TRUE
9 The Cancer Genome Atlas Brain Lower Grade Glioma KIAA1109 0.06 0.05 lasso 2 0.03 7.1e-05 7.4 -7.6 2.9e-14 -0.99 0.00 1.00 FALSE
10 The Cancer Genome Atlas Thyroid Carcinoma KIAA1109 0.05 0.04 enet 3 0.05 5.4e-06 7.0 -7.6 2.7e-14 -0.95 0.01 0.99 FALSE