[Hub]/) : Traits : Diabetes (self-reported) : ← →

chr11:16,709,350-18,106,069

Best TWAS P=8.92e-10 · Best GWAS P=1.4e-10 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KCNJ11 0.04 0.03 lasso 3 0.03 2.6e-04 6.4 6.1 8.9e-10 0.97 0.01 0.99 TRUE
2 GTEx Adipose Subcutaneous RP1-239B22.5 0.11 0.06 enet 21 0.07 1.5e-06 6.1 -5.4 7.8e-08 -0.80 0.01 0.99 FALSE
3 GTEx Esophagus Mucosa KCNJ11 0.27 0.16 lasso 8 0.22 1.6e-14 -3.8 -5.6 2.0e-08 -0.74 0.42 0.58 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic KCNJ11 0.18 0.07 lasso 6 0.12 7.0e-07 6.4 -5.9 4.7e-09 -0.88 0.01 0.99 FALSE
5 GTEx Skin Sun Exposed Lower leg KCNJ11 0.23 0.09 lasso 10 0.12 1.7e-10 6.3 -5.9 3.0e-09 -0.84 0.01 0.99 FALSE
6 GTEx Skin Sun Exposed Lower leg RP1-239B22.5 0.06 0.06 lasso 2 0.07 8.6e-07 -4.5 -5.9 4.3e-09 -0.75 0.03 0.96 FALSE
7 GTEx Thyroid RP1-239B22.5 0.08 0.07 enet 16 0.08 1.8e-06 6.2 -5.7 1.1e-08 -0.81 0.01 0.99 FALSE
8 The Cancer Genome Atlas Bladder Urothelial Carcinoma DKFZp686O24166 0.04 0.00 blup 71 0.02 7.1e-03 -4.6 -6.0 1.7e-09 -0.79 0.01 0.80 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DKFZp686O24166 0.05 0.03 blup 71 0.04 1.2e-05 -3.9 -5.5 3.1e-08 -0.80 0.03 0.96 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DKFZp686O24166 0.03 0.01 blup 72 0.03 2.4e-04 6.2 -5.8 5.9e-09 -0.81 0.01 0.96 FALSE
11 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DKFZp686O24166 0.08 0.07 lasso 4 0.05 1.2e-03 -3.9 -5.2 2.2e-07 -0.65 0.05 0.88 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma DKFZp686O24166 0.04 0.01 blup 71 0.02 1.5e-03 5.8 -5.6 1.6e-08 -0.84 0.01 0.90 FALSE