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chr11:16,709,350-18,106,069

Best TWAS P=8.92e-10 · Best GWAS P=1.4e-10 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	KCNJ11	0.04	0.03	lasso	3	0.03	2.6e-04	6.4	6.1	8.9e-10	0.97	0.01	0.99	TRUE
8	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DKFZp686O24166	0.04	0.00	blup	71	0.02	7.1e-03	-4.6	-6.0	1.7e-09	-0.79	0.01	0.80	FALSE
5	GTEx	Skin Sun Exposed Lower leg	KCNJ11	0.23	0.09	lasso	10	0.12	1.7e-10	6.3	-5.9	3.0e-09	-0.84	0.01	0.99	FALSE
6	GTEx	Skin Sun Exposed Lower leg	RP1-239B22.5	0.06	0.06	lasso	2	0.07	8.6e-07	-4.5	-5.9	4.3e-09	-0.75	0.03	0.96	FALSE
4	GTEx	Skin Not Sun Exposed Suprapubic	KCNJ11	0.18	0.07	lasso	6	0.12	7.0e-07	6.4	-5.9	4.7e-09	-0.88	0.01	0.99	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DKFZp686O24166	0.03	0.01	blup	72	0.03	2.4e-04	6.2	-5.8	5.9e-09	-0.81	0.01	0.96	FALSE
7	GTEx	Thyroid	RP1-239B22.5	0.08	0.07	enet	16	0.08	1.8e-06	6.2	-5.7	1.1e-08	-0.81	0.01	0.99	FALSE
12	The Cancer Genome Atlas	Lung Adenocarcinoma	DKFZp686O24166	0.04	0.01	blup	71	0.02	1.5e-03	5.8	-5.6	1.6e-08	-0.84	0.01	0.90	FALSE
3	GTEx	Esophagus Mucosa	KCNJ11	0.27	0.16	lasso	8	0.22	1.6e-14	-3.8	-5.6	2.0e-08	-0.74	0.42	0.58	FALSE
9	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DKFZp686O24166	0.05	0.03	blup	71	0.04	1.2e-05	-3.9	-5.5	3.1e-08	-0.80	0.03	0.96	FALSE
2	GTEx	Adipose Subcutaneous	RP1-239B22.5	0.11	0.06	enet	21	0.07	1.5e-06	6.1	-5.4	7.8e-08	-0.80	0.01	0.99	FALSE
11	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DKFZp686O24166	0.08	0.07	lasso	4	0.05	1.2e-03	-3.9	-5.2	2.2e-07	-0.65	0.05	0.88	FALSE