TWAS
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Genes
Traits
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Traits
:
Diabetes (self-reported)
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chr10:113,511,441-115,622,375
Best TWAS P=1.49e-36 · Best GWAS P=2.24e-124 conditioned to 2.14e-95
113.5M
114M
114.5M
115M
115.5M
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physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Artery Aorta
TCF7L2
0.19
0.09
lasso
6
0.05
0.001
12.651
-12.6
1.5e-36
-0.69
0.87
0.04
TRUE
2
NTR
Blood
VTI1A
0.02
0.00
blup
610
0.00
0.011
-0.096
-7.6
2.3e-14
-0.40
0.04
0.09
FALSE