[Hub]/) : Traits : Diabetes (self-reported) : ← →

chr3:48,757,291-50,833,360

Best TWAS P=1.89e-09 · Best GWAS P=2.75e-09 conditioned to 0.00497

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	RBM6	0.16	0.19	lasso	9	0.19	1.2e-22	-5.0	-5.2	1.5e-07	0.63	0.17	0.82	FALSE
2	CommonMind	Brain Pre-frontal Cortex	RNF123	0.14	0.10	blup	324	0.12	4.7e-14	4.8	5.3	1.4e-07	-0.51	0.69	0.30	FALSE
3	GTEx	Artery Aorta	UBA7	0.06	0.02	enet	12	0.01	5.3e-02	4.5	-5.3	1.0e-07	0.69	0.09	0.78	FALSE
4	GTEx	Brain Cortex	RBM6	0.21	0.25	lasso	4	0.29	8.8e-09	-5.0	-6.0	2.4e-09	0.84	0.06	0.94	FALSE
5	GTEx	Brain Cortex	RNF123	0.23	0.05	enet	33	0.04	2.4e-02	4.5	5.3	1.4e-07	-0.57	0.10	0.63	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	RBM6	0.20	0.19	enet	29	0.22	2.0e-06	-5.0	-5.9	4.2e-09	0.69	0.12	0.87	FALSE
7	GTEx	Cells Transformed fibroblasts	RBM6	0.27	0.29	enet	17	0.31	1.3e-23	-5.0	-5.2	2.3e-07	0.58	0.22	0.78	FALSE
8	GTEx	Lung	TCTA	0.09	0.01	enet	10	0.03	3.3e-03	3.2	5.5	4.1e-08	-0.26	0.06	0.10	TRUE
9	GTEx	Thyroid	MST1R	0.06	0.06	enet	9	0.05	1.7e-04	4.5	5.4	6.2e-08	-0.65	0.26	0.72	FALSE
10	METSIM	Adipose	RBM6	0.22	0.34	lasso	15	0.34	1.7e-52	-4.9	-5.4	8.6e-08	0.63	0.16	0.84	FALSE
11	METSIM	Adipose	RNF123	0.03	0.02	lasso	12	0.02	2.0e-04	4.5	5.3	1.5e-07	-0.57	0.25	0.71	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	RBM6	0.21	0.32	enet	31	0.34	1.5e-44	-5.0	-5.3	1.3e-07	0.60	0.23	0.77	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	RBM6	0.03	0.04	blup	79	0.05	9.5e-10	-5.0	-5.3	9.6e-08	0.61	0.17	0.82	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	UBA7	0.01	0.01	enet	5	0.01	6.6e-04	4.5	-5.4	7.6e-08	0.60	0.02	0.96	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	UBA7	0.11	0.06	enet	5	0.05	7.6e-04	4.5	-5.5	3.3e-08	0.60	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RBM6	0.09	0.11	blup	79	0.11	3.8e-12	-4.9	-5.2	2.0e-07	0.66	0.20	0.80	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	MST1R	0.08	0.07	enet	10	0.09	2.6e-10	4.5	5.2	2.3e-07	-0.50	0.02	0.98	FALSE
18	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RBM6	0.16	0.12	blup	79	0.09	4.4e-04	-5.0	-6.0	1.9e-09	0.68	0.12	0.85	TRUE