TWAS hub - FUCA1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Cells Transformed fibroblasts	0.2190	0.0490	3.4e-06	0.168	NA	0.175	NA	0.207	1.3e-12	NA	4.2e-13	NA	1.8e-15
2	GTEx	Heart Left Ventricle	0.1575	0.0420	6.2e-07	0.197	NA	0.200	NA	0.206	1.0e-10	NA	6.7e-11	NA	3.2e-11
3	GTEx	Skin Not Sun Exposed Suprapubic	0.1910	0.0700	3.8e-03	0.066	NA	0.006	NA	0.046	1.7e-04	NA	1.4e-01	NA	1.4e-03
4	GTEx	Skin Sun Exposed Lower leg	0.1440	0.0430	1.3e-04	0.083	NA	0.083	NA	0.081	2.4e-07	NA	2.3e-07	NA	3.3e-07
5	GTEx	Thyroid	0.0780	0.0340	3.6e-03	0.007	NA	0.011	NA	0.006	8.5e-02	NA	4.8e-02	NA	1.1e-01
6	NTR	Blood	0.0464	0.0112	2.9e-15	0.066	0.046	0.064	0.059	0.065	2.7e-20	1.7e-14	8.5e-20	2.2e-18	4.2e-20
7	YFS	Blood	0.1727	0.0242	0.0e+00	0.287	0.305	0.305	0.305	0.297	7.9e-95	6.6e-102	7.3e-102	4.0e-102	5.7e-99
8	TCGA	Breast Invasive Carcinoma	0.0110	0.0090	5.5e-03	0.009	0.006	0.001	NA	0.005	5.2e-03	1.6e-02	1.6e-01	NA	3.1e-02
9	TCGA	Ovarian Serous Cystadenocarcinoma	0.0420	0.0330	6.6e-03	0.053	0.034	0.027	NA	0.047	1.6e-04	2.4e-03	5.7e-03	NA	3.9e-04
10	TCGA	Prostate Adenocarcinoma	0.0904	0.0512	5.2e-05	0.036	0.026	0.023	NA	0.025	9.9e-05	8.8e-04	1.8e-03	NA	9.8e-04
11	TCGA	Testicular Germ Cell Tumors	0.1950	0.1010	5.6e-05	0.152	0.137	0.130	NA	0.132	4.9e-06	1.5e-05	2.5e-05	NA	2.2e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Blood Eosinophil Count	5.6	42.8	95.1	-1.9	8.5	-3.4	-4.7	-5.4	9.8	9.2	-8.9	-5.2	-5.5	-3.8
Hypothyroidism/myxoedema (self-reported)	5.0	9.8	26.9	-3.2	-4.1	-0.1	-0.5	3.0	-3.2	-3.8	3.9	-1.4	-1.6	5.2
Medication: Bendroflumethiazide	4.5	6.8	18.4	4.3	1.0	2.8	3.1	-0.5	0.3	0.8	-0.4	3.6	3.5	-3.4
Hypothyroidism (self reported)	4.3	9.9	28.1	-3.3	-4.0	-0.3	-0.9	2.9	-3.2	-3.7	3.9	-1.5	-1.6	5.3
Had major operations	4.0	4.7	7.9	-0.9	2.7	-1.3	-1.9	-2.5	2.8	2.8	-2.8	-1.9	-1.7	-1.0
Mother’s age at death	3.7	4.6	11.6	0.8	-2.7	1.6	1.6	1.4	-2.7	-3.4	2.9	2.0	1.6	1.3
Frequency of tenseness / restlessness in last 2 weeks	3.3	5.1	10.6	-1.7	-3.3	0.2	-0.1	3.0	-2.8	-2.4	3.0	-0.5	-0.5	3.2
Medication: Allopurinol	3.3	4.3	10.5	1.1	3.2	-0.4	-0.1	-1.6	2.9	3.2	-2.9	-0.2	-0.2	-2.5
Hearing aid user	3.2	3.6	10.4	2.9	1.2	1.6	2.0	0.4	0.6	0.4	-1.0	2.3	2.4	-3.2
Medication: Lisinopril	3.1	4.0	10.6	2.8	2.3	0.7	1.3	-1.3	1.1	2.0	-1.8	1.9	1.9	-3.2
Fractured/broken bones in last 5 years	3.1	4.0	10.8	3.3	0.3	2.4	2.1	0.0	0.1	-0.1	-0.1	2.8	2.7	-2.6
Pulse rate	3.0	5.0	8.5	1.8	-2.3	2.7	2.9	1.3	-2.5	-1.8	2.5	2.6	2.5	0.1
Fed-up feelings	2.8	5.1	11.2	-1.6	-3.4	-0.5	-0.4	1.6	-3.2	-3.2	3.0	-0.3	-0.3	3.1
Pulse wave peak to peak time	2.8	3.2	7.5	-2.7	0.0	-2.2	-2.1	0.3	0.5	0.2	-0.2	-2.4	-2.7	2.4
Major Depression (MDD)	2.6	3.2	7.7	-2.8	-0.4	-1.6	-2.3	-0.1	0.5	-0.0	0.0	-2.6	-2.6	2.3
Blood Red Count	2.6	24.8	48.2	-1.6	6.7	-4.0	-4.1	-4.0	6.9	6.5	-6.8	-4.1	-4.4	-2.5
Medication for pain relief, constipation, heartburn	2.6	4.5	11.6	-3.4	-1.2	-2.6	-2.3	-0.1	-0.8	-1.2	0.6	-2.5	-2.7	3.0
Qualifications: NVQ or HND or HNC or equivalent	2.6	3.1	6.6	-0.2	-2.5	0.8	0.6	1.9	-2.5	-2.6	2.5	0.8	0.8	1.6
Multivitamins +/- minerals	2.4	3.1	7.4	1.0	-2.1	1.3	1.6	0.6	-2.4	-2.7	2.1	1.8	1.8	0.4
Medication: Levothyroxine sodium	2.4	4.1	12.4	-1.7	-2.7	-0.3	0.2	1.9	-2.2	-2.4	2.7	-0.4	-0.8	3.5
Falls in the last year	2.4	3.2	4.9	1.1	-2.2	2.0	2.1	1.1	-2.0	-2.1	2.2	1.8	1.9	0.2
Pulse wave Arterial Stiffness index	2.4	2.8	6.2	2.5	0.2	2.0	1.9	-0.8	-0.3	-0.1	-0.1	2.1	2.5	-2.5
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.7	6.8	-2.0	1.6	-2.0	-2.3	-2.1	1.9	1.1	-2.0	-2.6	-2.2	-0.0
Sensitivity / hurt feelings	2.3	3.9	8.7	-1.1	-3.0	0.7	0.4	2.5	-2.4	-2.2	2.8	0.1	-0.1	2.7
Eye problems/disorders: None of the above	2.3	2.7	6.4	-2.0	0.7	-2.1	-2.5	-0.0	1.1	1.1	-1.1	-2.1	-2.3	0.9
Pulse rate, automated reading	2.3	7.5	13.0	2.8	-2.4	2.9	3.3	2.3	-2.9	-2.2	2.9	3.6	3.3	-0.1
Medication: Aspirin	2.3	3.0	7.6	2.4	1.2	1.5	1.6	-2.0	0.8	0.8	-0.9	1.7	2.0	-2.8
Forced vital capacity (FVC)	2.2	8.4	19.4	-4.2	0.6	-3.9	-3.1	-1.0	1.3	0.7	-1.0	-4.0	-4.4	3.1
Medication: Aspirin	2.2	2.9	7.3	2.4	1.2	1.6	1.8	-1.7	0.7	0.8	-0.9	1.7	2.0	-2.7
Medication: Co-codamol	2.1	2.4	5.4	1.5	1.9	0.4	0.4	-2.2	1.9	1.6	-1.9	0.6	0.4	-2.3
Neuroticism score	2.1	4.4	10.4	-1.3	-3.2	0.2	-0.0	1.8	-2.8	-3.0	2.9	-0.2	-0.2	2.8
Forced expiratory volume in 1-second (FEV1)	2.1	7.0	17.1	-4.1	-0.7	-3.3	-2.8	0.1	-0.2	-0.7	0.4	-3.5	-3.7	3.7
Birth weight	2.1	4.7	8.4	1.4	-2.3	2.5	2.9	1.5	-2.4	-2.3	2.5	2.3	2.1	0.6
Number of full sisters	2.1	2.5	6.3	0.1	2.1	-0.6	-0.5	-2.1	2.5	2.1	-2.1	-0.8	-1.1	-1.2
Loneliness, isolation	2.1	2.9	7.7	-1.6	-2.3	-0.9	-0.6	1.1	-2.2	-1.9	2.1	-0.5	-0.8	2.8
Friendships satisfaction	2.1	2.6	9.0	-1.8	-1.9	-1.1	-1.1	1.0	-1.3	-1.0	1.8	-0.9	-1.5	3.0
Systolic Blood Pressure	2.0	9.9	23.8	1.9	4.7	-0.7	-0.8	-2.5	4.4	4.9	-4.4	0.1	-0.5	-3.6
Had menopause	2.0	2.4	5.2	0.7	2.2	-0.0	-0.5	-1.9	2.1	1.8	-2.3	-0.3	-0.0	-2.2
Medication: Lansoprazole	2.0	2.3	7.2	1.3	1.8	0.8	0.3	-1.3	1.6	2.1	-1.7	0.2	0.9	-2.7
Guilty feelings	2.0	3.0	8.0	-1.2	-2.8	0.4	0.1	1.6	-2.4	-2.4	2.4	-0.3	0.1	1.8
Impedance of leg (right)	1.9	9.4	16.0	-1.6	3.5	-2.9	-2.4	-3.5	4.0	4.0	-3.5	-2.8	-3.2	-0.4
Supplements: Vitamin C	1.9	2.2	4.2	-2.1	-0.7	-1.9	-1.7	1.6	-0.6	-1.0	0.4	-1.6	-1.8	2.0
Illnesses of siblings: Diabetes	1.9	2.3	5.0	2.2	-0.2	2.2	2.0	0.2	-0.4	-0.0	0.5	2.0	2.2	-1.5
Breast cancer (self-reported)	1.9	2.3	7.1	-1.5	0.6	-2.1	-1.8	-2.7	0.8	0.2	-0.7	-1.5	-1.8	1.1
Eye problems/disorders: Glaucoma	1.9	2.2	5.4	-2.3	-1.5	-1.0	-0.8	1.5	-1.2	-1.2	1.1	-1.7	-1.3	2.1
Alcohol drinker status: Previous	1.9	2.2	4.7	-1.7	0.9	-1.5	-2.2	-0.3	1.4	1.1	-1.1	-2.0	-2.0	0.7
Happiness	1.8	2.2	5.1	-0.7	-2.2	0.5	0.2	0.8	-2.0	-2.1	2.2	0.2	0.2	2.0
Depression (self-reported)	1.8	2.2	5.5	-2.3	-1.2	-1.5	-1.1	0.7	-1.0	-0.5	0.9	-1.7	-1.7	2.3
Loud music exposure frequency	1.8	2.0	4.3	-1.9	0.3	-1.7	-2.0	-0.8	0.8	0.7	-0.5	-1.9	-2.1	1.2
Gout (self-reported)	1.8	2.5	6.3	0.2	2.5	-1.0	-0.3	-0.9	2.3	2.3	-2.3	-0.7	-0.9	-1.4
Ever depressed for a whole week	1.8	2.2	4.5	-0.6	2.0	-1.2	-1.6	-1.2	1.8	1.5	-2.1	-1.4	-1.1	-1.1
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	5.0	0.4	2.2	-0.5	-0.8	-1.7	2.2	2.0	-2.1	-0.5	-0.5	-1.6
Average weekly spirits intake	1.7	2.2	5.5	2.4	0.4	1.6	1.9	-1.4	0.3	0.4	-0.1	2.0	1.8	-1.7
Qualifications: CSEs or equivalent	1.7	2.3	5.6	-2.4	-0.2	-1.3	-1.2	-1.7	0.3	0.6	-0.2	-2.2	-2.2	1.8
Blood clot in the leg (DVT)	1.7	2.2	4.5	0.6	2.1	-0.2	-0.5	-1.6	2.1	2.0	-2.0	-0.3	-0.3	-1.8
Diabetes diagnosed by doctor	1.7	2.8	6.7	2.6	0.3	2.0	1.9	1.2	-0.2	0.5	-0.0	2.2	2.3	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	5.0	2.2	-0.0	1.4	1.6	0.3	-0.6	-0.1	0.3	2.2	2.1	-1.5
Alcohol drinker status: Never	1.7	2.0	4.7	2.0	-0.2	1.9	1.9	0.5	-0.5	-0.2	0.5	1.9	2.2	-1.5
Nervous feelings	1.6	3.1	7.5	-2.3	-1.7	-1.5	-1.5	1.8	-1.0	-0.9	1.2	-1.6	-2.1	2.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	3.3	0.7	-1.8	1.5	0.9	1.5	-1.5	-1.8	1.8	1.3	1.2	0.5
Number of operations (self-reported)	1.6	2.4	5.5	0.8	2.3	-0.2	-0.2	-1.8	2.1	1.7	-2.4	-0.3	0.1	-2.3
Blood White Count	1.5	11.3	25.0	5.0	-0.6	4.7	4.0	2.0	-1.1	-0.1	1.3	4.7	4.7	-3.1
Frequency of depressed mood in last 2 weeks	1.5	2.1	5.2	-2.3	-0.2	-1.5	-1.9	0.6	0.0	0.5	-0.1	-2.0	-2.0	1.7
Systolic blood pressure, automated reading	1.5	4.3	9.6	1.4	3.1	-0.2	-0.3	-1.8	2.9	3.1	-2.8	0.2	-0.1	-2.5
High blood pressure	1.5	4.1	12.7	2.9	1.9	1.7	1.6	-0.6	1.5	1.8	-1.7	1.7	2.0	-3.6
Birth weight of first child	1.5	2.7	4.7	1.4	-1.3	2.2	2.1	1.5	-1.6	-1.3	1.5	1.9	2.0	-0.3
Age at last live birth	1.5	2.2	6.3	0.5	-1.5	0.6	1.1	2.5	-1.8	-2.1	1.7	1.3	0.8	1.1
Alzheimer’s Disease (in father)	1.4	1.5	4.5	-1.6	-1.4	-0.6	-0.9	0.2	-0.7	-1.3	1.2	-0.9	-1.3	2.1
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	3.6	1.4	-0.7	1.9	1.7	-0.0	-0.9	-0.6	1.0	1.4	1.9	-0.7
Impedance of leg (left)	1.4	6.9	13.2	-1.4	2.9	-2.5	-1.9	-3.2	3.3	3.6	-2.9	-2.3	-2.8	-0.3
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	3.6	1.4	1.8	1.3	1.1	0.0	1.7	1.6	-1.4	0.5	0.7	-1.9
Medication: Blood pressure	1.4	2.5	9.2	2.0	1.5	1.4	1.0	-0.2	1.1	1.3	-1.4	1.1	1.6	-3.0
Medication: Ibuprofen	1.4	1.7	3.6	1.0	1.9	1.0	0.8	-0.4	1.8	1.8	-1.5	0.1	0.3	-1.8
Medication: Gliclazide	1.4	1.6	4.3	0.8	-1.1	1.6	2.1	1.0	-1.1	-1.6	1.1	1.0	1.3	-0.3
Bipolar Disorder (2018)	1.3	2.1	5.5	-1.8	0.2	-1.9	-2.3	-0.7	0.3	0.5	-0.3	-1.8	-1.9	1.7
Depression (Nagel 2018)	1.3	2.0	5.0	-2.2	-1.0	-1.3	-1.5	0.3	-0.7	-0.4	0.7	-1.7	-1.7	2.2
Alzheimer’s Disease (including proxy)	1.3	1.9	3.9	-1.1	-2.0	0.4	-0.1	1.9	-1.2	-1.7	1.8	-0.4	-0.6	2.0
Triglycerides	1.3	2.2	11.4	-0.4	-2.1	0.2	1.0	3.4	-2.0	-1.7	0.0	0.0	0.0	0.0
Number of treatments/medications taken	1.3	2.3	6.5	2.0	1.6	1.1	0.9	-0.6	1.5	1.7	-1.5	1.0	1.1	-2.5
Tense / ‘highly strung’	1.3	2.1	4.8	-2.1	-1.4	-1.3	-1.6	1.0	-1.0	-0.8	1.1	-1.5	-1.5	2.2
Peak expiratory flow (PEF)	1.3	3.0	6.5	-2.5	-0.4	-2.0	-2.2	-0.5	-0.1	-0.7	0.3	-2.1	-2.4	2.5
High blood pressure (siblings)	1.3	1.8	3.8	0.1	2.0	-0.7	-1.1	-1.1	1.6	1.9	-2.0	-0.7	-0.2	-1.6
Forced vital capacity (FVC), Best measure	1.3	4.9	12.5	-3.4	0.2	-2.8	-2.2	-0.3	0.8	0.4	-0.5	-3.1	-3.5	2.6
Heart disease (mother)	1.3	1.6	3.0	-0.5	1.5	-0.6	-0.4	-1.3	1.7	1.6	-1.7	-1.4	-0.8	-1.1
Hypertension (Self-reported)	1.3	3.6	10.4	2.7	1.7	1.7	1.5	-0.3	1.4	1.8	-1.5	1.7	1.8	-3.2
Handedness (chirality/laterality): Left-handed	1.3	1.6	4.0	1.0	1.6	0.8	0.3	-0.9	1.8	1.5	-1.6	0.2	0.4	-2.0
Eye problems/disorders: Cataract	1.3	1.6	4.2	1.5	-0.7	1.2	2.1	0.8	-1.0	-0.8	1.1	1.8	1.5	-0.2
Risk taking	1.3	2.0	4.4	1.6	-0.7	2.1	2.1	0.4	-0.9	-0.9	0.8	1.6	2.0	-1.1
Commuting to job workplace: Cycle	1.3	1.6	3.2	-1.0	1.2	-1.5	-1.5	-0.7	1.5	0.8	-1.4	-1.4	-1.8	0.3
Reaction Time	1.2	2.3	5.9	0.3	-2.4	0.7	0.5	1.2	-2.3	-1.4	2.4	1.2	1.0	1.3
Mean Putamen Volume	1.2	1.3	2.7	1.6	-0.2	1.4	1.6	0.9	-0.7	-0.3	0.4	1.4	1.6	-1.1
HbA1C	1.2	1.4	5.2	0.6	2.3	-0.7	-0.3	-1.5	1.8	1.8	0.0	0.0	0.0	0.0
Lupus	1.2	1.8	5.2	-1.5	-1.5	-0.2	-0.8	2.3	-1.0	-0.7	1.3	-0.8	-1.1	2.2
Age when periods started (menarche)	1.2	2.9	5.5	0.7	-2.2	2.2	1.7	1.6	-1.5	-2.0	2.3	1.4	1.0	1.2
Time employed in main current job	1.2	1.3	2.1	-0.5	1.3	-1.2	-1.3	-1.3	1.5	1.3	-1.3	-0.9	-1.4	0.1
Glaucoma (self-reported)	1.2	1.4	4.4	-2.1	0.2	-1.2	-0.9	0.4	0.4	0.3	-0.4	-2.0	-1.7	1.2
Number of children fathered	1.2	1.4	2.8	-1.0	1.0	-1.1	-1.7	-0.3	1.1	1.4	-1.4	-1.5	-1.1	-0.6
Tinnitus: Yes, now most or all of the time	1.2	1.4	3.3	1.8	0.7	1.1	1.6	-0.6	0.4	0.3	-0.5	1.5	1.4	-1.7
Pain experienced in last month	1.2	2.1	3.9	-1.6	0.8	-2.0	-1.9	-1.5	1.0	0.5	-0.8	-1.7	-1.9	1.2
Impedance of whole body	1.2	6.0	11.4	-1.4	2.6	-2.3	-1.8	-3.4	3.0	3.0	-2.8	-2.2	-2.5	-0.5
Ever used hormone-replacement therapy (HRT)	1.1	1.4	2.3	0.6	-1.4	1.4	1.0	0.7	-1.5	-1.4	1.5	1.0	1.3	0.3
Severe depression (siblings)	1.1	1.3	2.3	-1.4	0.2	-1.3	-1.5	-1.5	0.4	0.5	-0.4	-1.3	-1.5	1.0
Qualifications: None of the above	1.1	2.3	6.2	2.2	1.7	0.7	0.9	-1.2	1.4	1.5	-1.5	1.3	1.1	-2.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.4	8.6	-2.9	-0.7	-2.0	-1.7	0.4	-0.2	-0.5	0.5	-2.4	-2.7	2.8
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	6.2	-1.8	-1.0	-1.2	-0.8	1.2	-0.7	-0.7	1.0	-1.1	-1.5	2.5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.4	3.5	-1.9	-0.6	-1.5	-1.3	-0.2	-0.6	-0.0	0.4	-1.5	-1.4	1.8
Shortness of breath walking on level ground	1.1	1.4	3.5	-1.9	-0.2	-1.3	-1.4	-0.2	0.3	0.3	-0.1	-1.8	-1.7	1.2
Emphysema/chronic bronchitis	1.1	1.2	2.8	1.6	1.0	1.2	1.1	-0.4	0.8	0.6	-0.8	1.1	1.1	-1.7
Migraine (self-reported)	1.1	1.3	5.1	1.0	-0.7	1.2	1.1	2.3	-0.8	-1.0	0.8	1.0	1.3	-0.5
Irritability	1.1	1.8	4.6	-0.5	-1.9	0.7	0.1	1.6	-1.8	-2.1	1.8	-0.0	0.4	1.2
Myopia	1.1	1.6	4.0	-2.0	0.1	-1.3	-1.6	-0.8	0.5	-0.0	-0.3	-1.9	-1.9	1.3
Vascular/heart problems diagnosed by doctor	1.1	3.1	9.4	-2.6	-1.3	-1.7	-1.5	0.4	-1.0	-1.3	1.2	-1.7	-2.0	3.1
Verbal and Numeric Reasoning (VNR)	1.0	2.5	5.2	0.3	2.1	0.3	-0.1	-2.3	2.2	1.9	-2.1	-0.6	-0.1	-2.0
Crohns Disease (2012)	1.0	1.6	4.1	-0.1	1.6	-0.2	-0.2	-1.9	2.0	1.8	-1.6	-0.5	-0.5	-1.2
Cardiovascular Disease	1.0	3.2	10.0	2.7	1.4	1.5	1.2	-0.4	1.2	1.6	-1.4	1.7	1.7	-3.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	2.9	-1.6	-1.5	-0.7	-1.1	0.6	-1.3	-0.7	1.1	-1.0	-0.9	1.7
Headache pain in last month	1.0	1.7	3.2	1.8	0.7	1.6	1.8	1.4	0.5	1.0	-0.4	1.2	1.4	-1.6
Medication: Amlodipine	1.0	1.4	9.4	1.0	-0.7	1.1	0.9	3.1	-0.6	-0.0	0.8	1.2	0.7	-0.0
Age at first live birth	1.0	1.8	3.9	-1.2	-1.7	-0.4	-0.5	1.6	-1.5	-1.9	1.5	-0.3	-0.5	2.0
Overall health rating	1.0	2.2	8.5	1.4	-1.0	2.9	2.1	0.4	-0.6	-0.7	0.9	1.1	1.9	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.0	1.0	2.0	1.2	-0.6	1.3	1.4	-0.8	-0.5	-0.9	0.8	1.4	1.2	-0.3
Mineral and other dietary supplements	1.0	1.3	2.6	0.6	-1.5	1.3	1.0	0.2	-1.6	-1.0	1.6	1.2	1.3	0.3
Miserableness	1.0	1.8	5.0	0.5	-1.7	1.4	1.3	-0.3	-1.7	-2.2	1.6	0.9	1.2	0.2
Pack years of smoking	1.0	1.4	4.1	2.0	0.7	1.3	1.3	-0.4	0.3	0.3	-0.3	1.5	1.6	-1.7
Depressed Affect (Nagel 2018)	0.9	1.9	5.3	-0.0	-2.0	0.1	0.5	0.6	-2.1	-2.3	1.9	0.6	0.6	1.2
Rheumatoid Arthritis	0.9	1.2	2.9	1.3	0.4	1.6	1.4	-0.5	0.3	0.3	-0.2	0.9	1.6	-1.7
Medication for hormone replacement therapy	0.9	1.0	2.0	1.2	-0.4	0.8	1.3	0.9	-1.0	-0.5	0.7	1.4	1.4	-0.4
Pack years adult smoking proportion	0.9	1.4	4.2	2.1	0.4	1.4	1.4	0.4	0.1	0.2	0.0	1.7	1.5	-1.3
Illnesses of siblings	0.9	1.2	3.9	-1.0	-1.5	-0.1	0.3	0.6	-1.1	-1.3	1.5	-0.3	-0.6	2.0
Arm fat percentage (right)	0.9	3.4	9.3	2.5	0.2	3.1	2.0	-1.1	0.2	0.2	-0.1	1.9	2.4	-2.6
Medication: Cholesterol lowering	0.9	1.4	6.9	0.6	1.2	-0.2	-0.2	-2.6	1.0	1.1	-1.3	0.0	0.3	-1.6
Leg fat percentage (right)	0.9	3.3	8.8	1.9	2.0	1.5	0.6	-1.7	2.0	2.1	-1.9	0.7	1.2	-3.0
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.5	-1.3	-1.1	-0.9	-0.6	1.1	-0.8	-1.1	0.9	-0.9	-1.1	1.6
Illnesses of father: Heart disease	0.9	1.3	3.1	-1.5	-1.4	-1.1	-0.9	0.2	-1.0	-1.0	1.0	-0.9	-1.1	1.8
Mood swings	0.9	1.7	5.2	0.4	-1.6	0.9	0.7	0.9	-2.0	-2.3	1.4	0.8	1.3	0.0
Commuting to job workplace: Walk	0.9	1.0	3.0	-0.1	-1.2	0.2	0.5	1.7	-0.9	-1.3	1.3	0.3	-0.1	1.2
Leg fat percentage (left)	0.9	3.1	8.6	2.2	1.7	1.8	0.9	-1.6	1.6	1.9	-1.5	1.0	1.5	-2.9
Unable to work because of sickness or disability	0.9	1.1	3.3	-1.8	-0.7	-0.4	-1.1	0.3	-0.0	-0.3	0.5	-1.8	-1.4	1.4
Alzheimer’s Disease (in mother)	0.8	0.9	4.8	-0.2	-1.1	0.7	0.4	2.2	-1.0	-1.0	1.0	0.2	0.3	0.6
Type 2 Diabetes (T2D) (2018)	0.8	1.5	3.9	2.0	0.5	1.5	1.2	1.2	0.2	0.7	-0.2	1.5	1.5	-1.6
Supplements: Zinc	0.8	0.9	2.0	-1.3	-1.1	-1.0	-0.5	0.6	-0.6	-1.0	0.6	-0.9	-1.0	1.4
Medication: Metformin	0.8	1.1	2.2	1.4	0.5	1.2	1.5	0.8	0.2	0.7	-0.2	0.9	1.3	-1.5
Trunk fat percentage	0.8	3.0	8.8	2.1	1.3	2.2	1.2	-1.9	1.4	1.3	-1.3	1.0	1.6	-3.0
Townsend deprivation index at recruitment	0.8	1.1	2.9	1.3	0.5	1.7	1.4	-0.5	0.9	1.1	-0.4	0.9	0.9	-1.2
Relative age voice broke	0.8	1.3	3.2	0.9	-0.7	1.2	1.3	0.1	-1.2	-1.6	0.8	1.1	1.8	-0.8
Taking other prescription medications	0.8	1.2	3.8	0.1	1.2	0.6	-0.2	-1.0	1.9	1.3	-1.4	-0.8	-0.7	-1.1
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.8	0.7	1.3	0.1	-0.0	-1.1	1.0	1.0	-1.3	0.1	0.6	-1.7
Body mass index (BMI)	0.8	3.4	9.5	2.4	-0.4	3.1	2.0	0.5	-0.6	-0.6	0.5	2.1	2.7	-2.1
Waist circumference	0.8	3.1	8.8	2.3	-0.9	3.0	1.9	-0.4	-0.8	-0.6	1.0	2.1	2.5	-1.5
Alcohol intake versus 10 years previously	0.8	1.2	4.8	1.5	0.4	1.1	1.2	-0.0	0.2	0.3	-0.6	0.9	1.5	-2.2
Lung cancer (father)	0.8	0.9	2.6	0.8	1.2	0.4	0.5	-0.7	1.4	1.6	-1.1	0.1	0.1	-1.2
Illnesses of mother	0.8	1.0	2.0	-0.3	-1.4	0.2	0.9	0.1	-1.4	-1.4	1.4	0.4	0.2	1.2
Suffer from ‘nerves’	0.8	1.2	2.6	-1.6	-0.7	-1.3	-1.1	0.6	-0.2	0.1	0.3	-1.4	-1.5	1.5
Arm fat percentage (left)	0.8	3.2	8.2	2.4	0.5	2.8	1.7	-1.2	0.5	0.4	-0.5	1.6	2.3	-2.9
Illnesses of father: None of the above (group 1)	0.8	1.0	2.6	1.5	0.8	1.0	0.9	0.2	0.4	0.5	-0.6	1.1	1.3	-1.6
Commuting to job workplace: Public transport	0.8	0.9	2.7	0.1	-1.3	0.7	0.8	0.6	-1.4	-1.7	1.2	0.6	0.8	0.4
Medication: Blood pressure	0.8	1.5	4.3	2.1	0.7	1.3	1.0	-0.6	0.5	1.2	-0.3	1.7	1.4	-1.3
Cholesterol lowering medication	0.8	1.1	3.1	1.8	0.1	1.5	1.3	0.5	0.3	1.0	0.3	1.6	1.1	-0.7
Neuroticism (Nagel 2018)	0.7	1.7	3.9	-0.9	-2.0	-0.5	-0.0	1.2	-1.7	-1.7	1.7	-0.3	-0.4	1.8
Ovarian Cancer	0.7	0.9	4.1	-0.6	0.4	-1.0	-1.2	-2.0	0.9	0.1	-0.7	-0.8	-1.0	0.0
Diabetes (mother)	0.7	0.9	2.5	1.6	0.7	0.6	0.9	0.6	0.4	0.4	-0.5	1.2	1.0	-1.5
Diabetes (self-reported)	0.7	1.0	2.4	1.4	-0.1	1.1	0.8	1.6	-0.6	0.2	0.4	1.3	1.5	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.6	-0.4	1.0	-0.6	-0.8	-1.3	0.9	1.3	-1.2	-0.8	-0.4	-0.8
Mouth/teeth dental problems: Dentures	0.7	1.1	2.6	1.3	1.2	0.6	0.7	-1.0	1.6	0.8	-1.2	0.6	0.2	-1.5
Impedance of arm (left)	0.7	3.5	9.4	-1.0	1.9	-1.5	-1.2	-3.1	2.4	1.8	-2.2	-1.7	-1.8	-0.7
Exposure to tobacco smoke at home	0.7	0.8	1.7	0.2	-1.3	0.7	1.3	0.2	-1.2	-1.0	1.3	0.6	0.6	0.5
Breastfed as a baby	0.7	0.9	3.2	-1.0	-0.0	-1.8	-1.3	0.6	-0.1	0.4	-0.1	-0.9	-1.1	1.0
Medication: Ventolin 100micrograms inhaler	0.7	0.9	2.3	0.3	1.5	-0.6	-0.5	0.1	1.5	1.1	-1.4	-0.3	-0.6	-0.8
Body fat percentage	0.7	2.9	8.5	2.1	1.2	2.3	1.2	-1.6	1.3	1.2	-1.2	1.1	1.7	-2.9
Wheeze or whistling in the chest in last year	0.7	1.2	3.4	1.4	0.1	1.9	1.2	-0.0	0.2	-0.1	-0.1	1.0	1.5	-1.8
Family relationship satisfaction	0.7	0.9	2.3	-1.5	-0.5	-0.9	-0.9	-1.0	-0.3	-0.2	0.4	-1.2	-1.1	1.4
Average weekly red wine intake	0.7	1.0	3.1	-0.4	-1.2	-0.4	-0.4	0.9	-1.3	-1.1	1.4	0.4	-0.0	1.7
Osteoporosis (self-reported)	0.7	0.9	2.1	0.6	-0.8	0.6	0.9	-0.9	-1.3	-1.4	0.8	0.9	1.3	-0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	3.1	-1.8	0.0	-1.6	-1.2	1.2	0.2	0.1	-0.3	-1.5	-1.7	1.3
Supplements: Fish oil (including cod liver oil)	0.7	0.9	2.3	-1.0	0.8	-0.7	-0.9	-0.6	1.4	0.3	-0.9	-1.4	-1.5	0.5
Worry (Nagel 2018)	0.6	1.2	3.1	-1.4	-1.3	-1.0	-0.6	0.7	-0.9	-0.7	1.0	-1.0	-1.1	1.8
Fasting Glucose	0.6	0.7	2.7	0.5	-1.7	1.2	0.6	1.2	0.5	-0.9	0.0	0.0	0.0	0.0
Waist Hip Ratio (WHR)	0.6	2.7	5.3	1.3	-2.0	2.0	2.0	-0.0	-1.6	-1.2	2.3	1.9	1.6	0.6
Lung FEV1/FVC ratio	0.6	2.8	5.3	0.4	-2.0	1.4	1.3	1.9	-2.3	-2.0	2.3	1.3	1.5	0.9
Neuroticism	0.6	1.5	3.8	0.1	-1.9	0.8	0.4	0.9	-1.5	-2.0	1.8	0.6	0.4	1.1
Average weekly fortified wine intake	0.6	0.7	2.5	-1.1	0.1	-0.9	-1.0	-1.6	0.2	0.6	-0.3	-1.0	-0.9	0.6
Impedance of arm (right)	0.6	2.7	8.9	-0.6	1.6	-1.0	-0.7	-3.0	2.2	1.8	-1.9	-1.3	-1.5	-0.7
Father’s age at death	0.6	0.8	1.5	0.9	-0.7	1.2	1.0	0.2	-0.8	-0.6	1.0	1.2	1.1	0.3
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	3.1	-1.8	-0.9	-0.9	-0.7	0.3	-0.7	-0.3	0.7	-1.3	-1.0	1.6
Medication: Paracetamol	0.6	1.0	1.9	1.4	-0.5	1.1	1.4	1.2	-0.5	0.1	0.9	1.4	1.1	-0.1
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.3	0.9	-0.5	0.5	0.8	0.9	-0.9	-0.9	0.5	1.1	1.1	-0.4
Comparative height size at age 10	0.6	3.6	8.1	-2.8	-0.6	-2.2	-2.1	-0.7	-0.1	-0.2	0.3	-2.3	-2.7	2.8
Chest pain or discomfort	0.6	0.8	2.7	-0.4	0.9	0.4	-0.3	-0.8	1.6	1.0	-1.1	-1.0	-0.7	-0.7
Long-standing illness, disability or infirmity	0.6	0.9	3.0	1.3	0.6	1.3	0.8	-0.4	0.5	0.8	-0.6	0.7	1.1	-1.7
Osteoarthritis (self-reported)	0.6	0.8	2.0	0.3	-1.0	1.4	0.8	-0.8	-0.9	-1.2	1.0	0.4	1.0	-0.2
Ever smoked	0.6	1.1	4.0	-1.2	0.1	-1.2	-1.1	-2.0	0.4	0.3	-0.4	-1.2	-1.2	0.8
Diastolic blood pressure, automated reading	0.6	1.9	4.2	1.1	2.0	-0.2	-0.1	-1.0	1.8	1.8	-1.9	0.1	0.2	-2.0
Heart attack/myocardial infarction (self-reported)	0.6	0.7	2.2	-0.6	-1.4	0.6	0.8	-0.1	-0.7	-0.5	1.3	-0.1	-0.3	1.5
Schizophrenia vs Biploar Disorder	0.5	0.7	1.3	0.8	-0.8	1.1	1.0	0.2	-0.8	-0.5	0.8	1.0	1.2	-0.3
Lung FVC	0.5	2.4	5.4	-2.3	-0.4	-2.3	-1.6	1.3	-0.4	-0.5	0.1	-1.8	-2.0	1.9
Ever had hysterectomy (womb removed)	0.5	0.6	2.1	1.0	0.8	0.5	0.3	0.0	0.7	0.6	-0.7	0.6	0.8	-1.5
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.6	1.0	0.2	1.0	0.9	-0.8	0.3	-0.1	-0.2	0.7	0.9	-1.2
Angina	0.5	0.6	1.9	-0.2	-1.4	0.6	-0.1	0.1	-1.0	-0.9	1.3	0.2	0.3	0.9
Hand grip strength (right)	0.5	1.3	3.9	-0.3	-1.2	-0.8	-0.5	2.0	-1.5	-1.8	1.2	0.2	-0.0	1.2
Stomach or abdominal pain in last month	0.5	0.6	1.8	0.9	0.2	0.9	1.3	1.3	0.1	0.3	-0.1	0.8	0.7	-0.8
Medication: Atenolol	0.5	0.7	2.2	0.4	1.2	-0.5	-0.3	-1.5	1.0	0.9	-1.1	-0.0	-0.3	-0.6
Chronic bronchitis/emphysema (father)	0.5	0.6	1.4	-0.8	0.0	-0.9	-1.1	-1.2	0.1	0.5	0.0	-0.6	-1.0	1.1
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.4	-0.9	0.5	-0.9	-1.2	-1.1	0.5	-0.2	-0.6	-1.0	-0.9	0.3
Arm fat mass (right)	0.5	2.2	7.0	1.9	-0.2	2.6	1.6	-0.4	-0.2	-0.3	0.2	1.5	2.1	-1.9
Exposure to tobacco smoke outside home	0.5	0.7	1.7	-0.6	-1.2	0.5	0.6	0.5	-0.8	-0.9	1.1	-0.1	-0.3	1.3
Comparative body size at age 10	0.5	1.4	2.9	-0.8	-1.6	-0.0	-0.4	1.7	-1.5	-1.6	1.4	-0.0	-0.2	1.7
Neck or shoulder pain in last month	0.5	0.7	1.5	0.1	-1.0	1.2	1.1	0.9	-0.8	-0.3	1.1	0.3	0.5	0.5
Angina (self-reported)	0.5	0.7	2.0	-0.6	-1.4	0.3	-0.5	0.2	-1.0	-1.0	1.3	-0.1	-0.1	1.2
Medication: Seretide 50 evohaler	0.5	0.6	1.7	0.9	-0.6	1.2	1.3	0.3	-0.2	-0.5	0.5	0.8	0.8	-0.6
Mean time to correctly identify matches	0.5	0.9	2.8	-0.2	-1.7	0.0	-0.1	0.6	-1.3	-0.6	1.6	0.4	0.1	1.4
Whole body fat mass	0.5	2.0	5.6	1.9	0.6	2.3	1.3	-0.8	0.5	0.5	-0.6	1.2	1.7	-2.4
Leg fat mass (right)	0.5	1.8	5.4	1.7	1.0	1.9	0.8	-0.9	0.9	0.9	-0.9	0.9	1.4	-2.3
Mouth/teeth dental problems: Mouth ulcers	0.5	0.9	2.5	-0.1	-1.6	0.9	0.5	0.0	-0.7	-0.8	1.6	0.4	-0.1	1.5
Arm fat mass (left)	0.5	2.2	6.4	1.9	0.2	2.5	1.6	-0.6	0.1	-0.1	-0.1	1.4	2.0	-2.2
Illnesses of father: High blood pressure	0.5	0.6	1.3	0.7	-0.6	0.8	1.1	0.8	-0.8	-0.8	0.6	0.7	1.1	-0.5
Leg fat mass (left)	0.5	2.0	5.8	1.9	0.9	2.0	1.0	-0.8	0.7	0.8	-0.8	1.1	1.7	-2.4
Bipolar Disorder or Schizophrenia	0.4	1.0	2.3	-1.3	-0.1	-1.4	-1.3	-0.3	-0.3	0.4	0.1	-1.2	-1.3	1.5
Intelligence (Savage-Jansen 2018)	0.4	1.2	4.0	1.0	1.3	0.7	0.5	-0.9	0.9	1.1	-1.3	0.4	0.9	-2.0
Breast Cancer	0.4	0.9	2.2	1.2	0.1	1.4	1.0	0.6	-0.2	0.5	-0.1	1.2	1.5	-1.3
Neuroticism (2016)	0.4	0.6	2.0	-0.1	-1.2	0.5	-0.2	1.4	-0.4	-1.0	0.9	0.1	-0.4	0.9
BMI	0.4	2.1	6.9	1.9	0.3	2.6	1.3	0.8	0.2	0.3	-0.1	1.4	1.9	-2.0
Allergy or Eczema	0.4	0.9	1.7	-0.7	1.1	-1.1	-1.2	-0.9	1.0	0.3	-1.3	-1.1	-0.7	-0.7
Hearing difficulty/problems: Yes	0.4	0.6	2.4	1.1	0.6	0.4	0.5	0.2	0.4	0.3	-0.7	0.9	0.9	-1.6
Vitamin and mineral supplements	0.4	0.6	2.9	0.4	0.9	0.3	0.1	0.8	0.9	1.7	-0.7	-0.0	-0.1	-0.5
Diabetes (father)	0.4	0.5	1.4	0.9	0.7	0.5	0.7	0.1	0.4	0.8	-0.5	0.5	0.7	-1.2
Maternal smoking around birth	0.4	0.5	1.4	1.2	0.2	0.8	0.5	0.4	-0.1	0.3	-0.1	1.0	1.1	-1.0
Hayfever, allergic rhinitis or eczema	0.4	1.0	2.2	-1.2	0.8	-1.1	-1.3	-0.4	0.8	0.4	-1.0	-1.5	-1.1	-0.1
High blood pressure (mother)	0.4	0.5	1.3	0.9	0.7	1.1	0.2	0.6	0.5	0.2	-0.4	0.6	0.9	-1.1
Trunk fat mass	0.4	1.9	5.7	1.6	0.9	2.0	1.1	-1.3	1.0	0.8	-1.0	0.8	1.3	-2.4
Past tobacco smoking	0.4	0.7	2.9	1.0	0.3	0.7	0.8	1.7	-0.1	-0.0	-0.0	0.9	0.9	-0.8
Mouth/teeth dental problems	0.4	0.7	1.4	-1.1	-0.8	-0.5	-0.5	1.2	-1.1	-0.5	0.7	-0.7	-0.3	1.0
Heart attack	0.4	0.5	1.9	-0.6	-1.1	0.5	0.7	-0.2	-0.4	-0.2	1.1	-0.2	-0.5	1.4
Prospective memory result	0.4	0.5	1.2	0.9	0.3	0.9	0.8	-0.1	0.2	1.1	-0.1	0.6	0.9	-0.8
Standing height	0.4	4.0	8.1	-2.8	0.7	-2.7	-2.1	-1.9	0.8	0.3	-1.1	-2.8	-2.8	1.5
Length of working week for main job	0.4	0.4	1.1	-1.1	-0.3	-0.4	-0.6	0.5	0.1	0.0	-0.0	-1.0	-1.0	0.8
Number of full brothers	0.4	0.5	1.3	1.1	0.6	0.3	0.5	-1.1	0.1	0.2	-0.3	0.9	0.9	-1.0
Alcohol intake frequency.	0.4	0.8	3.1	0.7	1.1	0.2	-0.4	-0.5	1.0	1.2	-1.2	0.0	0.5	-1.8
Leg pain on walking	0.4	0.5	1.5	-1.1	0.2	-0.5	-0.6	-1.1	0.6	0.3	-0.4	-1.2	-0.9	0.1
Medication for cholesterol	0.4	0.6	1.7	-1.3	0.3	-0.6	-0.8	-0.7	0.5	-0.6	-0.6	-1.3	-1.0	0.1
Back pain experienced in last month	0.4	0.5	2.4	0.4	-0.3	1.5	1.1	-0.0	-0.5	-0.1	0.6	0.5	1.0	-0.3
Number of self-reported non-cancer illnesses	0.4	0.7	2.0	1.0	-0.5	1.4	1.1	-0.2	-0.3	-0.2	0.3	0.8	1.1	-1.0
Average weekly champagne plus white wine intake	0.4	0.5	2.7	-0.4	-0.6	-0.4	-0.1	1.6	-0.7	-0.7	0.6	-0.0	-0.1	0.8
Wears glasses or contact lenses	0.4	0.4	0.9	0.2	0.8	-0.2	-0.3	-0.7	0.9	0.9	-1.0	-0.3	-0.1	-1.0
Basal cell carcinoma (self-reported)	0.4	0.5	1.7	0.8	-0.2	1.3	1.1	0.4	0.0	-0.2	0.1	0.8	0.7	-0.6
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.3	-0.1	1.1	-0.8	-0.7	-0.2	1.0	0.7	0.0	0.0	0.0	0.0
Respiratory disease	0.3	0.6	1.7	0.2	1.2	-0.2	-0.5	-0.1	1.2	0.9	-1.3	-0.3	-0.4	-1.0
Supplements: Glucosamine	0.3	0.3	1.0	0.8	0.2	0.4	0.6	-0.5	-0.2	-0.2	-0.2	0.6	0.8	-1.0
Leg predicted mass (left)	0.3	1.4	3.6	0.6	-1.2	1.6	1.0	0.6	-1.4	-1.9	1.1	0.8	1.4	-0.3
Number of incorrect matches in round	0.3	0.5	1.4	-0.1	1.0	-0.1	-0.1	-0.5	1.0	1.2	-1.0	-0.4	-0.4	-0.7
Alcohol usually taken with meals	0.3	0.5	1.3	0.8	0.9	0.2	0.2	-1.1	0.6	0.8	-0.6	0.5	0.5	-0.9
Hair/balding pattern: Pattern 2	0.3	0.3	1.1	0.6	0.3	0.7	0.7	-0.6	0.5	0.2	-0.4	0.2	0.4	-1.0
Had other major operations	0.3	0.4	0.9	0.1	-0.8	0.8	1.0	0.2	-0.5	-0.9	0.8	0.4	0.4	0.4
Allergy	0.3	0.7	1.5	0.9	-0.8	0.7	1.0	0.2	-1.1	-0.2	1.0	1.2	1.1	0.1
Pain all over the body in last month	0.3	0.4	0.7	-0.4	0.6	-0.4	-0.6	-0.7	0.8	0.8	-0.6	-0.7	-0.5	-0.1
Hayfever/allergic rhinitis (self-reported)	0.3	0.3	0.9	-0.1	-0.8	-0.1	-0.5	1.0	-1.0	-0.8	0.6	0.2	0.4	0.1
Medication: Simvastatin	0.3	0.4	1.0	1.0	0.2	0.1	0.3	-0.6	-0.3	0.6	-0.1	0.9	1.0	-0.9
Fluid intelligence score	0.3	0.5	2.6	-0.2	0.6	0.2	-0.4	-1.6	0.8	0.3	-0.9	-0.5	-0.0	-1.0
Qualifications: A levels/AS levels or equivalent	0.3	0.6	2.0	-1.4	-0.5	-0.5	-0.3	0.7	-0.5	-0.3	0.4	-1.1	-0.6	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.5	0.9	-0.1	1.2	0.8	-0.0	0.3	-0.2	0.3	0.8	0.5	-0.4
Leg fat-free mass (right)	0.3	1.8	4.9	0.5	-1.6	1.6	1.0	0.9	-1.8	-2.2	1.5	0.8	1.4	-0.0
Ever had bowel cancer screening	0.3	0.4	2.4	-0.1	0.4	0.3	-0.1	-1.5	0.7	1.0	-0.2	-0.1	-0.4	0.3
Qualifications: nursing, teaching	0.3	0.5	2.2	-1.2	-0.2	-0.5	-0.6	1.5	-0.2	0.0	0.2	-1.0	-0.6	0.6
Leg predicted mass (right)	0.3	1.8	4.8	0.5	-1.5	1.6	1.0	0.9	-1.8	-2.2	1.4	0.9	1.4	-0.0
Financial situation satisfaction	0.3	0.4	1.1	-0.5	-1.0	-0.1	0.1	-0.6	-0.8	-0.5	0.9	-0.2	-0.2	1.1
Age started oral contraceptive pill	0.3	0.4	2.4	-0.2	-0.4	-0.4	-0.1	1.6	-0.6	-0.9	0.4	0.1	0.0	0.6
Supplements: Calcium	0.3	0.3	0.8	0.5	-0.6	0.1	0.7	0.0	-0.6	-0.9	0.5	0.8	0.4	0.2
Crohns Disease (2017)	0.2	0.4	1.0	0.4	0.9	0.6	-0.0	-0.8	0.7	1.0	-0.7	-0.2	0.2	-0.7
Prostate Cancer	0.2	0.3	3.2	-0.1	0.3	-0.1	0.2	-1.8	0.3	-0.1	-0.3	-0.1	0.1	-0.4
Age at First Birth	0.2	0.3	1.7	-0.6	-0.7	-0.5	-0.5	1.3	-0.6	-0.7	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.2	0.2	1.0	1.0	0.4	0.7	1.0	0.1	0.2	0.2	0.0	0.0	0.0	0.0
Primary Biliary Cirrhosis	0.2	0.3	1.7	0.6	-0.3	0.1	-0.1	-1.3	-0.1	-0.6	0.3	0.6	0.4	-0.2
Schizophrenia (2014)	0.2	0.3	0.9	-0.7	-0.2	-1.0	-0.7	0.2	-0.5	0.1	0.3	-0.4	-0.5	1.0
Heel T-Score	0.2	1.4	2.9	-1.6	0.4	-1.7	-1.6	-1.2	0.5	-0.1	-0.4	-1.4	-1.6	1.2
Smoking Status	0.2	0.5	1.0	1.0	-0.2	1.0	0.8	-0.7	-0.2	-0.0	0.4	0.9	0.9	-0.4
Chronotype (morning person)	0.2	0.5	1.6	0.8	0.3	0.8	1.3	1.1	0.1	-0.1	-0.1	0.7	0.7	-0.7
Hair Pigment	0.2	5.5	10.5	2.7	-1.3	3.2	2.7	1.2	-1.4	-2.6	1.4	2.7	3.2	-1.9
Hand grip strength (left)	0.2	0.4	2.3	-0.2	-0.3	-0.8	-0.3	1.5	-0.5	-0.7	0.4	0.0	-0.3	0.7
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.9	-0.4	0.4	0.2	-0.2	-0.9	0.7	0.8	-0.5	-0.8	-0.4	-0.2
Leg fat-free mass (left)	0.2	1.1	3.2	0.5	-1.0	1.5	0.8	0.5	-1.3	-1.8	1.0	0.7	1.2	-0.3
Hip circumference	0.2	1.0	3.2	1.1	0.5	1.7	0.7	-0.7	0.5	0.1	-0.6	0.5	1.1	-1.8
Worrier / anxious feelings	0.2	0.4	2.0	-0.2	-0.6	-0.5	-0.1	1.4	-0.3	-0.4	0.6	-0.0	-0.7	1.1
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.9	-0.7	-0.9	0.6	-0.2	0.1	-0.7	-0.7	0.7	-0.4	0.0	0.6
Hair/balding pattern: Pattern 3	0.2	0.2	0.5	-0.3	-0.6	0.6	0.0	0.5	-0.7	-0.4	0.7	0.1	0.2	0.6
Number of live births	0.2	0.3	0.6	0.4	-0.4	0.8	0.3	-0.5	-0.2	-0.5	0.8	0.6	0.3	0.6
Noisy workplace	0.2	0.3	1.4	0.5	0.4	0.5	-0.1	-0.3	0.3	0.1	-0.5	0.3	0.6	-1.2
Hair/balding pattern: Pattern 4	0.2	0.4	1.7	0.7	0.8	0.2	0.2	-0.5	0.3	0.5	-0.7	0.3	0.7	-1.3
Pulse wave reflection index	0.2	0.3	1.2	0.2	0.4	0.2	0.2	-1.0	0.2	-0.4	-0.6	0.0	0.5	-1.1
Chronic bronchitis/emphysema (mother)	0.2	0.3	1.1	-0.1	0.3	-0.6	-0.6	0.9	0.1	1.1	-0.3	-0.2	-0.3	0.1
Qualifications: College or University degree	0.2	0.7	2.0	-1.3	-0.6	-0.7	-0.3	0.9	-0.5	-0.4	0.5	-0.9	-0.9	1.4
Mouth/teeth dental problems: Loose teeth	0.2	0.3	0.9	-0.1	-0.4	-0.2	-0.3	0.3	-0.9	-0.8	0.6	0.2	0.5	0.5
Medication: Omeprazole	0.2	0.2	0.6	-0.4	-0.4	0.6	-0.4	-0.8	0.5	0.0	0.1	-0.4	-0.6	0.3
Knee pain experienced in last month	0.2	0.3	1.1	0.5	-0.1	0.7	0.6	-0.4	-0.0	0.1	-0.2	0.3	0.6	-1.0
Whole body fat-free mass	0.2	0.9	2.8	0.0	-1.2	0.9	0.5	0.5	-1.4	-1.7	1.2	0.4	0.8	0.4
Whole body water mass	0.2	0.9	2.7	0.1	-1.2	0.9	0.6	0.5	-1.4	-1.6	1.2	0.4	0.8	0.3
Ever taken oral contraceptive pill	0.2	0.2	0.6	-0.1	-0.6	0.5	0.4	-0.4	-0.2	-0.5	0.7	0.1	-0.2	0.7
High cholesterol (Self-reported)	0.2	0.4	1.2	0.7	0.5	0.1	0.3	-0.8	0.4	1.1	-0.5	0.5	0.4	-0.8
Medication: Atorvastatin	0.2	0.2	0.7	-0.4	0.1	0.6	-0.3	0.1	0.8	0.6	-0.2	-0.5	-0.7	0.3
Average weekly beer plus cider intake	0.2	0.3	0.7	0.6	-0.2	0.3	0.7	-0.0	-0.5	-0.5	0.2	0.6	0.8	-0.7
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.7	-0.2	0.5	0.3	-0.3	-0.8	0.7	0.5	-0.3	-0.3	-0.4	0.2
Heart disease (siblings)	0.2	0.2	0.5	-0.6	0.2	-0.7	-0.6	-0.4	0.1	0.2	-0.5	-0.7	-0.4	-0.3
Irritable Bowel Disease (IBD)	0.1	0.2	1.0	-0.3	0.4	0.4	-0.4	-1.0	0.5	0.4	-0.3	-0.7	-0.3	-0.0
Ulcerative Colitis (UC)	0.1	0.2	0.5	-0.6	-0.3	0.2	-0.7	-0.3	-0.1	-0.5	0.3	-0.6	-0.5	0.6
Coronary Artery Disease (CAD)	0.1	0.1	0.4	0.0	0.7	-0.2	-0.2	-0.4	0.3	0.0	0.0	0.0	0.0	0.0
HDL Cholesterol	0.1	0.2	0.6	0.8	-0.5	0.1	0.6	-0.1	-0.7	-0.7	0.0	0.0	0.0	0.0
LDL Cholesterol	0.1	0.2	0.7	-0.8	-0.2	-0.8	-0.5	-0.4	-0.3	-0.4	0.0	0.0	0.0	0.0
Ulcerative Colitis	0.1	0.2	0.7	-0.8	-0.2	-0.4	-0.5	0.1	0.2	-0.3	0.2	-0.5	-0.6	0.5
Blood Platelet Count	0.1	0.6	2.6	0.8	-0.2	0.5	0.3	1.6	-0.8	-0.3	0.3	0.9	1.1	-0.5
Height	0.1	1.9	4.0	-2.0	0.1	-1.7	-1.1	-1.6	0.4	-0.1	-0.5	-2.0	-2.0	1.2
Tanning	0.1	1.2	5.0	0.3	1.4	-0.4	-0.8	-2.2	1.1	1.0	-1.4	-0.2	-0.2	-1.2
Relative age of first facial hair	0.1	0.3	0.7	0.4	-0.4	0.4	0.5	-0.4	-0.6	-0.8	0.4	0.5	0.8	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.9	-0.3	0.3	-0.8	-0.9	0.9	0.2	0.3	-0.3	-0.3	-0.5	0.2
Serious illness, injury or assault to yourself	0.1	0.1	0.4	-0.1	0.1	0.6	0.0	-0.2	0.4	0.6	-0.1	-0.3	-0.1	-0.1
Sitting height	0.1	1.1	2.5	-1.6	0.1	-1.5	-1.3	0.3	-0.1	-0.2	-0.4	-1.5	-1.4	0.9
Hearing difficulty/problems with background noise	0.1	0.2	0.9	0.3	0.3	-0.2	-0.2	-1.0	-0.1	0.3	-0.3	0.3	0.4	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.9	0.6	0.0	0.3	0.3	1.0	-0.2	-0.2	0.1	0.7	0.4	-0.3
Medication: Ramipril	0.1	0.1	0.6	0.1	0.0	0.4	-0.2	-0.3	0.3	0.8	0.1	0.1	-0.1	0.2
Weight	0.1	0.7	2.5	0.9	-0.0	1.6	0.8	-0.4	-0.2	-0.4	-0.0	0.6	1.2	-1.2
Trunk fat-free mass	0.1	0.4	1.2	-0.5	-0.9	0.1	-0.0	0.3	-1.0	-1.1	0.8	-0.2	-0.0	0.8
Asthma	0.1	0.2	0.4	0.4	0.4	0.6	0.5	0.6	0.7	0.1	-0.4	0.1	0.1	-0.6
Trunk predicted mass	0.1	0.4	1.2	-0.6	-0.9	0.0	-0.1	0.2	-1.0	-1.1	0.8	-0.3	-0.1	0.8
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.5	-0.5	-0.3	-0.3	-0.6	0.7	-0.4	-0.2	0.1	-0.5	-0.1	0.2
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.6	0.1	0.8	0.0	-0.1	-0.5	0.6	0.6	-0.5	-0.1	-0.0	-0.3
Arm fat-free mass (right)	0.1	0.5	1.5	0.2	-0.7	0.8	0.4	0.5	-1.1	-1.2	0.7	0.3	0.9	-0.1
Worry too long after embarrassment	0.1	0.2	0.4	-0.5	-0.5	-0.3	-0.3	0.4	-0.2	-0.6	0.2	-0.5	-0.4	0.4
Health satisfaction	0.1	0.1	0.3	-0.2	-0.5	0.5	0.1	-0.5	0.2	-0.2	0.4	-0.3	-0.3	0.2
Arm predicted mass (right)	0.1	0.3	0.9	0.1	-0.5	0.5	0.2	0.6	-0.8	-0.9	0.5	0.2	0.6	-0.1
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.5	-0.2	-0.1	0.2	-0.2	-0.3	-0.3	0.7	0.1	-0.2	0.4	-0.2
Smoking status: Previous	0.1	0.2	1.5	0.2	-0.2	0.4	0.2	-1.2	0.0	-0.2	0.1	0.1	0.3	-0.3
Asthma (self-reported)	0.1	0.2	0.7	0.2	0.6	0.2	0.1	0.3	0.8	0.4	-0.6	-0.1	-0.2	-0.6
Smoking status: Current	0.1	0.1	0.5	-0.5	0.0	-0.5	-0.3	0.0	0.0	0.2	0.0	-0.3	-0.5	0.7
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.5	-0.1	-0.4	0.6	0.5	0.7	0.0	0.1	0.5	-0.1	-0.2	0.6
Medication: Paracetamol	0.1	0.2	0.5	0.4	-0.3	0.3	0.7	0.7	-0.2	0.4	0.6	0.4	0.2	0.5
Basal metabolic rate	0.1	0.6	1.7	0.3	-0.9	1.0	0.6	0.2	-1.1	-1.3	0.8	0.4	0.8	-0.1
Arm fat-free mass (left)	0.1	0.7	1.5	0.4	-0.9	1.0	0.8	0.4	-1.2	-1.2	0.9	0.6	1.0	0.0
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.5	-0.3	-0.2	0.4	-0.7	-0.6	0.6	0.1	-0.2	-0.4	-0.5	-0.1
Arm predicted mass (left)	0.1	0.6	1.1	0.5	-0.7	0.9	0.7	0.5	-1.1	-1.1	0.8	0.6	1.0	-0.1
Schizophrenia (2018)	0.0	0.1	0.3	-0.1	-0.3	-0.3	0.4	0.2	-0.6	0.1	0.3	0.2	-0.0	0.5
Bipolar Disorder (2011)	0.0	0.0	0.1	0.0	0.0	0.0	0.0	0.0	0.0	-0.3	0.0	0.0	0.0	0.0
Current tobacco smoking	0.0	0.1	0.3	-0.2	-0.3	-0.1	0.0	0.5	-0.3	-0.1	0.3	0.0	-0.1	0.5
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.2	0.1	0.1	-0.2	-0.1	-0.4	0.1	0.4	-0.1	0.1	0.0	-0.2
Financial difficulties in last 2 years	0.0	0.0	0.1	-0.1	0.2	0.1	0.3	0.1	-0.2	0.3	0.0	-0.1	0.3	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.1	0.4	0.0	-0.1	0.1	0.4	-0.6	-0.0	0.0	-0.1	-0.0	0.0	-0.2

Hub : Genes

FUCA1

Models

Trait associations