Best TWAS P=7.89e-08 · Best GWAS P=4.35e-08 conditioned to 0.191
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Nucleus accumbens basal ganglia | CTCF | 0.11 | 0.03 | lasso | 5 | 0.04 | 2.4e-02 | 4.3 | 5.1 | 2.6e-07 | 0.74 | 0.07 | 0.44 | FALSE |
| 2 | GTEx | Spleen | ATP6V0D1 | 0.36 | 0.03 | enet | 9 | 0.07 | 6.0e-03 | 3.7 | -5.2 | 1.6e-07 | -0.85 | 0.02 | 0.45 | FALSE |
| 3 | YFS | Blood | ATP6V0D1 | 0.14 | 0.18 | lasso | 15 | 0.20 | 1.8e-63 | 5.3 | -5.4 | 7.9e-08 | -0.93 | 0.02 | 0.98 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TPPP3 | 0.03 | 0.02 | blup | 31 | 0.04 | 2.1e-05 | 4.8 | -5.2 | 2.1e-07 | -0.92 | 0.03 | 0.96 | FALSE |