Best TWAS P=6.26e-09 · Best GWAS P=1.82e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | DOK6 | 0.18 | 0.18 | lasso | 5 | 0.18 | 3.2e-56 | 5.9 | 5.8 | 6.3e-09 | 0.96 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CD226 | 0.04 | 0.04 | enet | 7 | 0.05 | 5.3e-10 | 5.9 | -5.7 | 1.2e-08 | -0.91 | 0.00 | 1.00 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CD226 | 0.09 | 0.03 | blup | 76 | 0.06 | 1.7e-07 | 5.9 | -5.1 | 3.1e-07 | -0.81 | 0.00 | 1.00 | FALSE |