[Hub]/) : Traits : Hypothyroidism/myxoedema (self-reported) :

chr18:66,371,289-68,204,223

Best TWAS P=6.26e-09 · Best GWAS P=1.82e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 NTR Blood DOK6 0.18 0.18 lasso 5 0.18 3.2e-56 5.9 5.8 6.3e-09 0.96 0.01 0.99 TRUE
2 The Cancer Genome Atlas Breast Invasive Carcinoma CD226 0.04 0.04 enet 7 0.05 5.3e-10 5.9 -5.7 1.2e-08 -0.91 0.00 1.00 FALSE
3 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CD226 0.09 0.03 blup 76 0.06 1.7e-07 5.9 -5.1 3.1e-07 -0.81 0.00 1.00 FALSE