[Hub]/) : Traits : Hayfever/allergic rhinitis (self-reported) :

chr5:109,381,583-111,527,482

Best TWAS P=3.24e-15 · Best GWAS P=8.33e-18 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Spleen SLC25A46 0.25 0.00 enet 6 0.02 1.3e-01 5.4 -5.3 1.3e-07 0.01 0.07 0.06 TRUE
2 GTEx Testis WDR36 0.61 0.37 lasso 10 0.34 5.7e-16 -4.5 -5.3 1.5e-07 0.57 1.00 0.00 FALSE
3 METSIM Adipose CAMK4 0.05 0.01 bslmm 518 0.03 8.3e-05 5.6 5.5 3.2e-08 -0.61 0.04 0.87 TRUE
4 METSIM Adipose TSLP 0.16 0.18 lasso 7 0.18 8.5e-26 -7.2 7.1 1.2e-12 -0.92 0.30 0.70 FALSE
5 ROSMAP Brain Pre-frontal Cortex TSLP 0.13 0.08 enet 14 0.09 4.1e-11 -6.8 5.7 1.5e-08 -0.73 1.00 0.00 TRUE
6 ROSMAP Brain Pre-frontal Cortex CAMK4 0.10 0.03 lasso 4 0.04 7.8e-06 5.8 -6.4 1.4e-10 0.59 0.91 0.08 TRUE
7 YFS Blood SLC25A46 0.03 0.02 enet 12 0.02 9.5e-07 5.4 -7.9 3.2e-15 0.25 0.94 0.01 TRUE
8 The Cancer Genome Atlas Breast Invasive Carcinoma TSLP 0.03 0.03 lasso 2 0.03 5.5e-07 -7.1 6.1 1.2e-09 -0.84 0.62 0.38 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma TSLP 0.08 0.01 blup 39 0.03 5.4e-03 -6.8 5.6 2.5e-08 -0.78 0.04 0.13 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TSLP 0.05 0.02 blup 39 0.02 7.9e-04 -6.8 6.0 2.3e-09 -0.77 0.08 0.67 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma TSLP 0.06 0.07 blup 39 0.06 6.4e-07 -6.8 6.7 2.1e-11 -0.88 0.72 0.28 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma TSLP 0.02 0.02 blup 39 0.02 1.9e-03 -7.1 6.5 6.6e-11 -0.88 0.05 0.09 FALSE
13 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TSLP 0.04 0.03 enet 6 0.02 1.6e-03 -7.0 6.3 4.0e-10 -0.86 0.06 0.60 TRUE
14 The Cancer Genome Atlas Testicular Germ Cell Tumors TSLP 0.12 0.11 lasso 3 0.08 6.9e-04 -7.2 7.3 3.1e-13 -0.92 0.07 0.38 TRUE
15 The Cancer Genome Atlas Thyroid Carcinoma TSLP 0.13 0.14 blup 39 0.15 1.4e-14 -6.8 5.6 2.8e-08 -0.75 0.82 0.18 TRUE