[Hub]/) : Traits : Gout (self-reported) : ← →

chr4:9,370,814-11,156,010

Best TWAS P=3.23e-70 · Best GWAS P=2.9e-88 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	WDR1	0.04	0.01	enet	10	0.03	3.8e-04	-13.1	6.1	9.4e-10	-0.06	0.27	0.02	TRUE
2	GTEx	Adipose Subcutaneous	SLC2A9	0.06	0.06	lasso	2	0.04	6.1e-04	-13.0	12.9	3.7e-38	-0.38	0.42	0.06	FALSE
3	GTEx	Adipose Subcutaneous	RP11-448G15.3	0.08	0.06	lasso	4	0.07	3.8e-06	7.2	6.5	7.7e-11	-0.40	0.69	0.02	FALSE
4	GTEx	Adipose Visceral Omentum	SLC2A9	0.15	0.02	lasso	4	0.04	3.6e-03	11.8	9.4	4.4e-21	-0.19	0.31	0.08	FALSE
5	GTEx	Adipose Visceral Omentum	RP11-448G15.3	0.10	0.02	lasso	6	0.03	9.6e-03	-19.1	17.7	3.2e-70	-0.65	0.10	0.19	TRUE
6	GTEx	Adrenal Gland	RP11-448G15.3	0.10	0.07	enet	10	0.05	9.2e-03	7.2	10.4	1.9e-25	-0.56	0.11	0.44	FALSE
7	GTEx	Artery Aorta	SLC2A9	0.06	0.08	enet	4	0.08	3.7e-05	6.5	6.8	7.4e-12	-0.40	0.86	0.01	FALSE
8	GTEx	Artery Aorta	RP11-448G15.3	0.11	0.10	lasso	4	0.07	6.6e-05	7.2	5.7	1.4e-08	-0.34	0.88	0.01	FALSE
9	GTEx	Artery Coronary	SLC2A9	0.11	0.11	enet	4	0.08	8.6e-04	5.9	9.4	4.1e-21	-0.32	0.42	0.06	FALSE
10	GTEx	Artery Tibial	WDR1	0.19	0.06	enet	26	0.10	1.6e-08	6.8	9.1	8.7e-20	-0.44	0.99	0.00	FALSE
11	GTEx	Artery Tibial	SLC2A9	0.25	0.29	lasso	6	0.27	4.2e-21	7.2	7.8	5.7e-15	-0.42	1.00	0.00	FALSE
12	GTEx	Artery Tibial	ZNF518B	0.06	0.07	lasso	4	0.04	2.2e-04	6.9	6.9	4.5e-12	-0.27	0.94	0.00	FALSE
13	GTEx	Artery Tibial	RP11-448G15.3	0.22	0.11	enet	25	0.16	8.7e-13	7.2	8.5	1.6e-17	-0.40	0.98	0.00	FALSE
14	GTEx	Breast Mammary Tissue	RP11-448G15.3	0.18	0.01	lasso	10	0.07	2.2e-04	-15.3	13.7	1.5e-42	-0.69	0.41	0.22	FALSE
15	GTEx	Cells EBV-transformed lymphocytes	SLC2A9	0.25	0.18	lasso	6	0.18	2.0e-06	-4.6	-5.9	3.3e-09	0.46	0.87	0.05	TRUE
16	GTEx	Cells Transformed fibroblasts	RP11-448G15.3	0.07	0.03	lasso	3	0.03	3.8e-03	6.8	7.4	1.3e-13	-0.35	0.75	0.01	FALSE
17	GTEx	Colon Sigmoid	SLC2A9	0.26	0.11	lasso	13	0.15	5.9e-06	5.8	7.6	2.9e-14	-0.34	0.67	0.05	TRUE
18	GTEx	Colon Transverse	SLC2A9	0.08	0.04	lasso	1	0.01	7.7e-02	6.7	6.7	2.4e-11	-0.37	0.19	0.04	TRUE
19	GTEx	Colon Transverse	RP11-448G15.3	0.12	0.00	lasso	6	0.00	6.5e-01	7.7	6.5	1.1e-10	-0.14	0.20	0.04	TRUE
20	GTEx	Esophagus Gastroesophageal Junction	SLC2A9	0.18	0.10	enet	25	0.12	6.2e-05	7.2	5.6	1.9e-08	-0.27	0.15	0.06	FALSE
21	GTEx	Esophagus Mucosa	RP11-448G15.3	0.07	0.01	enet	10	0.02	1.2e-02	-2.6	10.1	4.8e-24	-0.32	0.37	0.06	TRUE
22	GTEx	Esophagus Muscularis	SLC2A9	0.19	0.14	lasso	6	0.22	1.2e-13	6.0	8.2	1.6e-16	-0.36	1.00	0.00	FALSE
23	GTEx	Esophagus Muscularis	RP11-448G15.3	0.11	0.00	enet	14	0.03	1.1e-02	-2.6	8.4	3.3e-17	-0.36	0.25	0.07	FALSE
24	GTEx	Liver	SLC2A9	0.18	0.13	lasso	6	0.12	3.7e-04	6.5	8.3	1.4e-16	-0.04	0.34	0.04	TRUE
25	GTEx	Nerve Tibial	WDR1	0.12	0.02	lasso	5	0.03	1.8e-03	7.9	11.6	3.2e-31	-0.44	0.32	0.18	FALSE
26	GTEx	Nerve Tibial	RP11-448G15.3	0.22	0.10	enet	27	0.23	2.6e-16	7.2	10.9	1.5e-27	-0.41	1.00	0.00	FALSE
27	GTEx	Skin Sun Exposed Lower leg	SLC2A9	0.18	0.03	enet	15	0.06	1.2e-05	12.3	11.9	6.7e-33	-0.27	0.57	0.06	FALSE
28	GTEx	Thyroid	RP11-448G15.3	0.17	0.05	enet	40	0.12	1.3e-09	7.2	6.6	5.4e-11	-0.29	0.90	0.00	FALSE
29	GTEx	Whole Blood	SLC2A9	0.11	0.04	lasso	6	0.05	9.9e-06	6.0	6.7	2.7e-11	-0.38	0.92	0.00	FALSE
30	METSIM	Adipose	SLC2A9	0.05	0.04	lasso	4	0.03	9.3e-06	11.8	10.9	1.5e-27	-0.25	1.00	0.00	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	RP11-448G15.3	0.06	0.04	blup	552	0.05	7.9e-07	7.2	12.2	4.8e-34	-0.58	0.96	0.03	FALSE
32	The Cancer Genome Atlas	Breast Invasive Carcinoma	WDR1	0.04	0.02	lasso	5	0.03	1.7e-06	-8.0	-5.3	1.1e-07	0.06	0.98	0.00	TRUE
33	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	ZNF518B	0.08	0.04	lasso	2	0.01	1.2e-01	-6.3	-6.5	9.5e-11	0.22	0.02	0.11	FALSE
34	The Cancer Genome Atlas	Esophageal Carcinoma	SLC2A9	0.16	0.02	enet	20	0.05	1.4e-02	6.6	5.8	6.4e-09	-0.12	0.04	0.05	FALSE
35	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ZNF518B	0.09	0.01	enet	8	0.04	2.7e-05	-6.3	-5.9	3.0e-09	0.12	0.27	0.04	FALSE
36	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SLC2A9	0.11	0.06	lasso	2	0.05	3.9e-04	6.0	-6.5	1.1e-10	0.29	0.56	0.07	FALSE
37	The Cancer Genome Atlas	Stomach Adenocarcinoma	WDR1	0.06	0.03	blup	111	0.01	3.2e-02	6.7	-9.2	4.8e-20	0.31	0.02	0.58	FALSE