Best TWAS P=1.78e-09 · Best GWAS P=1.61e-10 conditioned to 0.0298
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | TMEM110 | 0.17 | 0.05 | lasso | 8 | 0.07 | 3.1e-03 | 5.5 | -5.4 | 7.9e-08 | -0.87 | 0.03 | 0.87 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SFMBT1 | 0.40 | 0.17 | lasso | 6 | 0.17 | 1.9e-18 | 5.5 | -6.0 | 1.8e-09 | -0.93 | 0.06 | 0.94 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SFMBT1 | 0.17 | 0.14 | lasso | 6 | 0.14 | 2.5e-08 | 5.4 | -5.9 | 4.4e-09 | -0.92 | 0.01 | 0.99 | FALSE |