Best TWAS P=2.85e-14 · Best GWAS P=3.81e-39 conditioned to 1.59e-28
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Colon Adenocarcinoma | LRPPRC | 0.17 | 0.00 | lasso | 7 | 0.07 | 0.00012 | 1.39 | -5.5 | 2.8e-08 | -0.01 | 0.19 | 0.04 | TRUE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | LRPPRC | 0.18 | 0.05 | blup | 109 | 0.01 | 0.12800 | -4.42 | -5.4 | 7.9e-08 | -0.06 | 0.12 | 0.04 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | LRPPRC | 0.10 | 0.02 | blup | 109 | 0.05 | 0.00068 | 0.17 | -5.5 | 3.2e-08 | -0.22 | 0.08 | 0.21 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ABCG5 | 0.05 | 0.04 | blup | 75 | 0.02 | 0.00160 | -4.73 | 7.6 | 2.8e-14 | 0.35 | 0.42 | 0.13 | TRUE |