Best TWAS P=8.83e-09 · Best GWAS P=9.93e-09 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | ARHGAP42 | 0.22 | 0.15 | enet | 18 | 0.19 | 1.7e-10 | -5.5 | -5.3 | 1.1e-07 | 0.86 | 0 | 1 | FALSE |
2 | GTEx | Artery Tibial | ARHGAP42 | 0.24 | 0.24 | lasso | 4 | 0.24 | 2.4e-18 | -5.7 | -5.8 | 8.8e-09 | 0.98 | 0 | 1 | TRUE |
3 | GTEx | Artery Tibial | TMEM133 | 0.26 | 0.25 | enet | 28 | 0.27 | 1.3e-21 | -5.7 | -5.2 | 1.7e-07 | 0.94 | 0 | 1 | FALSE |