TWAS hub - ARHGAP42

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0750	0.0260	7.6e-04	0.034	0.029	0.046	0.027	0.005	4.9e-05	0.00017	2.8e-06	0.00027	7.6e-02
2	GTEx	Artery Aorta	0.2160	0.0560	4.3e-05	0.147	NA	0.186	NA	0.161	1.7e-08	NA	1.7e-10	NA	3.3e-09
3	GTEx	Artery Tibial	0.2373	0.0453	1.4e-10	0.241	NA	0.229	NA	0.235	7.3e-19	NA	7.3e-18	NA	2.4e-18
4	GTEx	Cells Transformed fibroblasts	0.1470	0.0440	1.8e-04	0.098	NA	0.075	NA	0.066	9.1e-08	NA	2.6e-06	NA	1.1e-05
5	GTEx	Muscle Skeletal	0.0916	0.0339	1.3e-03	0.030	NA	0.064	NA	0.044	6.0e-04	NA	7.0e-07	NA	3.2e-05
6	ROSMAP	Brain Pre-frontal Cortex	0.0403	0.0198	2.4e-02	0.002	0.000	0.000	0.000	0.002	1.5e-01	0.27000	3.4e-01	0.28000	1.9e-01
7	TCGA	Breast Invasive Carcinoma	0.0383	0.0154	2.9e-04	0.009	0.018	0.005	NA	0.008	4.2e-03	0.00011	2.6e-02	NA	7.8e-03
8	TCGA	Prostate Adenocarcinoma	0.0594	0.0287	5.7e-03	0.009	0.016	0.011	NA	0.009	3.2e-02	0.00710	2.4e-02	NA	3.7e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8
Systolic Blood Pressure	30.6	153.2	372.5	-11.4	-17.7	-19.3	-9.6	-3.0	-11.1	-13.6	-0.6
Systolic blood pressure, automated reading	23.3	67.7	156.2	-8.0	-11.5	-12.5	-6.9	-1.2	-7.9	-8.7	1.3
Vascular/heart problems diagnosed by doctor	21.2	57.7	149.9	6.5	11.2	12.2	6.2	1.3	6.0	8.4	0.3
Diastolic blood pressure, automated reading	20.1	62.4	158.8	-6.5	-11.3	-12.6	-6.6	-1.8	-7.1	-8.5	0.5
Hypertension (Self-reported)	19.6	54.6	156.2	-5.8	-11.0	-12.5	-6.1	0.1	-5.2	-7.9	-0.1
High blood pressure	19.0	52.8	148.8	-5.9	-10.9	-12.2	-5.6	-0.7	-5.4	-7.7	0.2
Cardiovascular Disease	16.8	55.5	182.2	-4.1	-11.3	-13.5	-6.6	-0.2	-4.0	-7.6	-0.7
Medication: Blood pressure	16.0	28.3	72.1	-4.2	-7.8	-8.5	-4.4	-0.5	-4.0	-6.1	-1.3
Medication: Blood pressure	14.8	28.3	79.7	-3.1	-8.0	-8.9	-5.4	0.4	-4.1	-5.2	0.1
Medication for cholesterol, blood pressure or diabetes	13.9	23.0	55.0	4.0	6.9	7.4	4.3	1.9	3.4	5.4	1.5
Medication: Ramipril	10.5	13.4	33.1	-2.8	-5.3	-5.8	-3.3	-1.1	-3.0	-3.9	-1.3
Medication: Amlodipine	9.1	12.8	33.8	-2.1	-5.5	-5.8	-2.5	-0.4	-3.2	-3.9	-1.6
Medication: Cholesterol lowering	8.8	13.6	26.1	-3.6	-5.1	-4.9	-3.0	-2.8	-2.7	-4.3	-1.7
Medication: Atenolol	7.3	9.2	22.0	-2.2	-4.7	-4.7	-3.0	-0.8	-2.0	-3.4	-0.3
High blood pressure (siblings)	7.1	10.2	23.6	-1.9	-4.9	-4.8	-3.8	0.1	-2.0	-3.6	0.1
Medication: Bendroflumethiazide	6.6	10.0	27.5	-3.2	-4.9	-5.2	-2.4	0.6	-3.0	-1.5	0.8
Lung FEV1/FVC ratio	6.2	31.3	58.9	6.3	5.9	6.4	7.1	1.6	3.7	7.7	3.2
Illnesses of siblings	5.9	8.2	16.9	2.5	4.0	4.1	3.3	-0.1	2.6	3.0	0.1
Medication for cholesterol	5.9	8.9	26.7	0.5	4.4	5.2	4.1	-1.2	1.0	2.3	-0.6
Medication: Lisinopril	5.5	7.1	19.9	-2.0	-4.0	-4.5	-2.2	0.8	-1.9	-2.8	-0.3
Heart attack	5.3	6.8	12.2	-3.0	-3.2	-2.2	-2.1	-2.9	-1.8	-3.5	-1.4
Angina	5.1	6.7	12.0	-2.9	-3.0	-3.4	-0.9	-1.7	-3.5	-3.0	-0.5
Angina (self-reported)	5.0	6.5	10.8	-2.9	-2.9	-3.3	-1.3	-1.8	-3.3	-2.9	-0.7
High cholesterol (Self-reported)	4.9	8.7	22.6	-1.9	-4.6	-4.8	-3.6	-0.5	-0.8	-3.0	0.3
Heart attack/myocardial infarction (self-reported)	4.9	6.4	11.2	-3.1	-3.0	-1.9	-1.8	-3.1	-1.7	-3.3	-1.4
Number of treatments/medications taken	4.8	8.6	24.3	-1.2	-4.4	-4.9	-2.3	-0.6	-2.6	-3.3	0.4
High blood pressure (mother)	4.6	6.4	21.2	-1.2	-3.9	-4.6	-2.5	0.0	-0.7	-2.6	-0.3
Illnesses of mother	4.5	5.5	15.2	1.6	3.4	3.9	2.4	-0.3	1.9	2.1	-0.9
Medication: Simvastatin	4.4	6.4	13.2	-2.7	-3.4	-3.6	-1.8	-0.6	-2.4	-3.1	-0.3
Coronary Artery Disease (CAD)	4.0	4.8	10.1	-3.0	-1.7	-1.0	-1.6	-1.5	-2.0	-2.5	-3.2
Length of working week for main job	4.0	4.4	9.7	1.2	2.2	2.0	2.0	-0.1	2.2	3.1	2.5
Illnesses of father: High blood pressure	3.6	4.5	15.3	-0.5	-3.1	-3.9	-1.9	0.2	-1.0	-2.3	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.5	4.0	9.3	1.2	3.0	1.9	2.8	0.4	1.0	2.4	1.8
Loneliness, isolation	3.4	4.7	8.2	1.9	2.9	1.7	2.3	1.8	1.5	2.7	2.2
Number of full sisters	3.1	3.7	8.3	-2.2	-1.9	-1.5	0.3	-2.0	-2.9	-2.2	-1.5
Forced expiratory volume in 1-second (FEV1)	3.0	10.2	21.2	2.3	4.3	4.6	3.5	-0.1	2.7	4.1	-0.4
Heel bone mineral density (BMD) T-score, automated (left)	2.9	6.6	13.6	-2.2	-3.1	-3.7	-1.6	-1.5	-3.5	-2.8	0.4
Had other major operations	2.8	3.5	8.1	1.4	2.0	2.9	1.6	-0.6	2.0	2.5	0.5
Illnesses of father: None of the above (group 1)	2.8	3.5	9.4	1.4	2.9	3.1	1.9	0.1	1.4	1.5	0.4
Blood White Count	2.7	20.2	44.9	-6.7	-5.4	-5.0	-4.8	-2.5	-4.6	-3.2	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.7	5.7	15.4	1.4	3.3	3.3	1.7	0.6	2.0	3.9	-0.3
Sensitivity / hurt feelings	2.6	4.5	9.3	1.6	3.0	2.5	2.8	0.3	1.4	2.0	1.9
Allergy or Eczema	2.5	6.5	11.7	3.2	2.6	3.1	2.4	0.8	3.4	2.4	1.3
Time employed in main current job	2.5	2.8	4.6	2.1	1.8	1.5	1.6	1.4	1.6	1.6	1.7
Had major operations	2.5	2.9	7.3	-2.0	-1.2	-1.2	-0.8	-1.6	-2.1	-2.7	-1.1
Medication: Atorvastatin	2.5	3.0	7.1	-0.9	-2.2	-1.9	-2.7	-1.4	-0.6	-1.5	-1.7
Average weekly fortified wine intake	2.4	2.8	6.4	0.6	1.6	1.4	2.4	2.5	1.0	1.7	1.3
Heel bone mineral density (BMD) T-score, automated (right)	2.4	5.6	14.7	-2.1	-3.0	-3.8	-0.9	-1.1	-3.2	-1.5	1.3
Alzheimer’s Disease (in mother)	2.2	2.5	5.9	-2.1	-2.4	-1.9	-1.2	-0.3	-1.1	-1.8	0.2
Medication: Gliclazide	2.2	2.5	5.7	1.4	2.0	2.1	2.4	0.8	0.4	1.7	0.6
Medication: Lansoprazole	2.1	2.3	9.5	-0.3	0.6	-0.2	2.8	0.3	-0.4	0.6	3.1
Forced expiratory volume in 1-second (FEV1), Best measure	2.1	6.7	14.1	2.4	3.5	3.8	2.3	-0.7	2.2	3.1	-0.8
Medication: Co-codamol	2.0	2.3	5.1	0.9	2.0	1.4	0.8	-0.6	0.9	2.2	2.1
Number of incorrect matches in round	2.0	3.3	11.0	-1.8	-1.6	-1.2	-3.3	1.2	-2.3	-0.7	-0.6
Pulse wave reflection index	2.0	2.5	5.0	-0.7	-1.8	-2.2	-1.4	0.4	-2.2	-1.9	-0.1
Number of self-reported non-cancer illnesses	2.0	3.4	10.9	-1.1	-2.9	-3.3	-1.0	0.1	-1.2	-1.3	1.8
Financial situation satisfaction	2.0	2.5	5.9	2.4	1.5	0.9	0.8	1.8	2.4	1.1	0.6
Irritability	2.0	3.4	6.4	0.9	2.4	1.4	2.2	2.5	1.2	0.8	2.3
Qualifications: O levels/GCSEs or equivalent	1.9	3.0	6.4	2.0	2.2	2.5	0.1	0.7	2.4	1.6	-0.2
Birth weight	1.9	4.2	10.4	1.3	3.1	2.9	0.1	0.7	3.2	1.5	-0.8
Heart disease (mother)	1.9	2.4	3.9	-2.0	-1.8	-1.7	-0.8	-1.8	-1.4	-1.6	-0.3
Emphysema/chronic bronchitis	1.8	2.1	4.3	-1.7	-0.8	-2.1	-0.5	-0.5	-2.0	-1.8	1.0
Illnesses of father: Heart disease	1.8	2.5	8.8	-0.2	-2.8	-3.0	-0.4	-0.7	-1.2	-1.1	-0.0
Lupus	1.7	2.6	7.8	0.4	2.1	1.1	2.8	2.6	0.2	0.7	0.4
Multivitamins +/- minerals	1.7	2.1	6.1	2.5	0.7	0.0	0.4	1.8	2.2	1.6	-0.3
Happiness	1.7	2.1	6.0	2.0	1.2	0.6	-0.5	2.5	2.2	0.3	-0.1
Chronic bronchitis/emphysema (mother)	1.7	1.9	4.1	-0.7	-2.0	-1.8	-0.9	-1.0	-2.0	-1.2	0.6
Medication: Aspirin	1.7	2.3	5.9	-1.6	-1.9	-2.4	0.0	-0.2	-1.9	-1.6	0.6
Heart disease (siblings)	1.7	2.1	4.6	-1.3	-1.1	-1.2	-1.6	-0.6	-0.9	1.9	2.1
Supplements: Zinc	1.6	1.8	4.3	-1.5	-1.2	-0.7	1.0	-0.5	-2.1	-2.1	-0.4
Hayfever/allergic rhinitis (self-reported)	1.6	2.1	5.7	2.4	1.4	1.3	0.6	1.2	1.7	1.6	-0.7
Neuroticism score	1.6	3.4	5.9	1.4	2.4	1.5	1.6	2.4	0.5	2.1	2.0
Worry too long after embarrassment	1.6	2.6	6.7	0.4	2.6	2.2	1.3	1.8	0.7	1.8	0.9
Basal cell carcinoma (self-reported)	1.6	2.0	3.5	1.7	1.9	1.2	1.5	1.0	1.2	1.1	1.3
HbA1C	1.5	1.7	3.8	-0.1	-1.3	-1.2	-2.0	0.3	-1.6	-1.8	-1.0
Rheumatoid Arthritis	1.5	2.1	5.0	-0.9	2.0	0.7	1.7	-0.8	-0.0	2.2	1.6
Hayfever, allergic rhinitis or eczema	1.5	3.4	6.3	2.5	1.6	2.4	2.1	-0.2	2.4	1.5	0.1
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	5.7	1.1	2.4	1.9	1.1	1.7	1.1	1.4	0.9
Hair/balding pattern: Pattern 2	1.5	1.9	7.1	1.7	1.0	1.1	-0.6	2.7	1.3	0.0	-0.7
Birth weight of first child	1.5	2.6	4.9	1.1	2.1	2.2	1.5	0.5	1.8	2.0	0.9
Medication: Aspirin	1.5	2.0	5.3	-1.1	-1.9	-2.3	-0.2	0.1	-1.8	-1.6	0.1
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	9.5	1.5	-0.3	-0.5	0.1	-0.3	0.4	0.6	-3.1
Osteoarthritis (self-reported)	1.5	2.0	5.9	0.8	1.3	1.3	2.4	-0.4	-0.7	1.6	1.6
Cholesterol lowering medication	1.5	2.2	5.2	-0.5	-2.0	-2.1	-2.3	1.3	-0.3	-1.1	1.0
Intelligence (Savage-Jansen 2018)	1.4	4.1	8.2	2.9	2.2	1.6	1.8	0.9	2.5	2.6	0.7
Heel T-Score	1.4	11.1	28.6	-3.5	-4.7	-5.3	-0.8	-1.0	-3.7	-3.2	0.1
Neuroticism	1.4	3.4	7.9	1.3	2.8	1.7	1.8	2.5	0.4	1.6	1.8
Allergy	1.4	3.2	6.0	-2.2	-1.4	-1.8	-2.4	0.5	-1.7	-1.7	-2.0
Blood clot in the leg (DVT)	1.4	1.8	6.0	2.5	0.5	0.3	0.3	-0.3	1.6	2.1	1.1
Exposure to tobacco smoke outside home	1.4	1.8	4.2	0.9	0.6	0.2	-0.2	1.6	1.7	2.1	1.9
Illness, injury, bereavement, stress in last 2 years	1.4	1.7	8.5	0.9	0.7	0.2	-0.1	1.4	1.3	2.9	-0.4
Taking other prescription medications	1.3	1.9	4.3	-0.9	-0.9	-2.0	0.2	0.4	-2.1	-1.7	1.5
Forced vital capacity (FVC)	1.3	5.0	12.5	0.7	3.4	3.5	1.9	-1.0	1.5	2.5	-1.5
Pulse wave peak to peak time	1.3	1.6	4.5	0.8	1.6	2.1	0.2	-0.1	2.0	0.9	-0.3
Supplements: Fish oil (including cod liver oil)	1.3	1.7	4.2	0.7	0.7	0.5	1.6	2.0	0.6	2.0	1.1
Neuroticism (2016)	1.2	1.8	6.4	0.2	1.6	1.6	2.5	-0.7	0.4	1.3	0.6
Relative age of first facial hair	1.2	2.4	4.6	1.1	2.1	2.1	1.9	0.5	-0.2	0.9	2.1
Age when periods started (menarche)	1.2	3.0	6.2	0.9	2.1	1.8	2.4	-0.1	1.0	2.5	1.6
Pain all over the body in last month	1.2	1.3	3.9	-1.4	-0.7	-0.3	0.0	-1.7	-2.0	-0.2	1.1
Falls in the last year	1.2	1.6	8.0	1.0	0.3	-0.0	0.5	0.2	0.6	2.8	1.9
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.9	4.5	1.5	2.0	1.2	0.7	2.1	0.3	0.6	1.2
Peak expiratory flow (PEF)	1.2	2.8	4.7	1.6	1.5	2.2	1.3	-1.4	2.1	2.1	-0.8
Age at last live birth	1.2	1.7	3.9	0.8	1.5	2.0	1.3	0.2	1.1	1.1	-1.6
Guilty feelings	1.2	1.9	5.6	0.5	2.4	1.7	1.3	0.5	-0.7	1.5	1.2
Vitamin and mineral supplements	1.1	1.5	7.4	-0.7	0.5	1.6	-0.2	-2.7	-1.0	0.1	-0.6
Impedance of leg (right)	1.1	5.2	18.7	-1.8	-2.8	-4.3	-1.1	-0.9	-2.1	-2.2	1.0
Leg fat-free mass (left)	1.1	5.7	15.8	2.2	2.8	4.0	1.5	0.8	2.7	2.7	0.6
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	5.7	1.1	-0.2	-0.6	-2.4	1.4	0.8	0.5	0.2
Impedance of leg (left)	1.1	5.5	18.9	-2.3	-2.9	-4.4	-0.9	-0.8	-2.3	-2.1	0.9
Leg predicted mass (left)	1.1	5.6	15.8	2.1	2.7	4.0	1.5	0.8	2.7	2.6	0.6
Trunk fat-free mass	1.1	6.1	16.6	2.1	3.1	4.1	1.5	0.6	2.8	2.8	0.2
Depression (self-reported)	1.1	1.3	3.5	0.8	1.7	1.1	1.9	0.4	-0.5	0.3	1.2
Arm fat-free mass (right)	1.1	5.9	11.2	2.0	2.7	3.4	1.6	0.7	3.2	3.1	0.9
Arm predicted mass (right)	1.1	5.4	10.8	1.9	2.5	3.2	1.5	0.5	3.2	3.3	0.7
Family relationship satisfaction	1.1	1.3	3.4	-0.4	-1.0	-1.6	-1.8	-0.0	-0.1	-1.0	-1.5
Illnesses of siblings: Diabetes	1.1	1.3	4.5	-1.7	-0.7	-0.7	-0.7	0.2	-2.1	-1.3	-0.2
Whole body fat-free mass	1.1	6.1	16.2	2.1	3.0	4.0	1.5	0.7	3.0	2.8	0.4
Leg fat-free mass (right)	1.1	6.1	17.1	2.1	2.8	4.1	1.5	1.0	2.8	2.7	0.3
Breast cancer (self-reported)	1.1	1.4	4.1	-0.6	1.7	2.0	0.6	-1.1	-1.2	-0.1	-0.9
Whole body water mass	1.1	6.3	16.3	2.2	3.0	4.0	1.5	0.8	3.0	2.8	0.4
Leg predicted mass (right)	1.1	5.9	17.0	2.1	2.8	4.1	1.5	1.0	2.8	2.7	0.4
Impedance of whole body	1.1	5.7	14.6	-2.4	-2.8	-3.8	-1.0	-1.1	-2.7	-2.7	0.7
Alzheimer’s Disease (including proxy)	1.0	1.5	3.9	-1.2	-2.0	-1.1	-0.9	-0.2	-0.9	-1.6	-1.0
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	3.2	1.0	-0.4	-0.2	0.1	-0.1	1.8	1.6	1.5
Maternal smoking around birth	1.0	1.4	3.3	-0.9	-1.5	-1.5	-1.3	-1.8	0.1	0.6	-0.6
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	2.9	0.4	-0.1	-0.2	-1.7	1.3	1.6	-0.5	-0.9
Ever unenthusiastic/disinterested for a whole week	1.0	1.3	4.7	2.2	0.4	-0.4	0.3	1.6	1.4	-0.6	0.0
Fluid intelligence score	1.0	2.1	3.6	1.9	1.4	0.8	0.6	1.8	1.7	1.6	1.1
Number of live births	1.0	1.4	4.7	-0.7	-1.0	-1.4	-0.2	-1.4	-2.2	-0.7	-0.7
Pulse rate	1.0	1.6	4.2	1.2	1.5	2.0	1.3	0.3	0.5	1.7	-0.3
Pulse wave Arterial Stiffness index	1.0	1.2	3.5	-0.7	-1.3	-1.9	0.0	0.1	-1.7	-0.7	0.2
Trunk predicted mass	1.0	5.7	15.5	2.0	3.0	3.9	1.5	0.6	2.8	2.6	0.3
Loud music exposure frequency	1.0	1.1	4.6	1.2	0.4	-0.5	0.7	2.1	0.9	0.9	0.2
Health satisfaction	1.0	1.3	5.8	1.2	-0.0	-0.4	-0.5	2.4	1.0	-0.4	1.1
Mouth/teeth dental problems: Loose teeth	1.0	1.2	3.8	-1.9	0.7	0.0	0.8	0.6	-1.4	-1.1	1.2
Mean time to correctly identify matches	1.0	1.8	4.7	-0.7	-2.1	-2.2	-1.6	0.2	-0.5	-1.3	-0.7
Mood swings	1.0	1.8	12.3	0.9	-0.0	-0.8	-0.2	3.5	0.5	-0.1	0.4
Eye problems/disorders: Cataract	1.0	1.2	4.0	0.4	0.6	0.2	0.7	-1.1	-0.0	2.0	1.8
Hearing aid user	1.0	1.1	3.5	0.1	1.2	1.0	-1.2	0.3	1.9	0.7	-0.6
Arm predicted mass (left)	1.0	5.3	10.4	2.0	2.6	3.1	1.1	0.8	3.2	3.0	0.9
Ulcerative Colitis (UC)	0.9	1.6	6.2	1.6	-0.7	-1.6	2.5	-0.5	-0.0	-0.8	-0.2
Age at First Birth	0.9	1.4	3.1	1.4	1.3	1.3	1.4	0.3	0.6	1.8	-0.2
Ulcerative Colitis	0.9	1.3	3.8	0.8	-1.5	-2.0	1.6	-0.8	-0.4	-0.5	-0.3
Blood Eosinophil Count	0.9	6.7	14.7	-3.8	-2.8	-2.5	-1.5	-2.4	-2.8	-2.7	-1.5
Smoking Status	0.9	2.1	8.2	-0.8	-0.8	-1.0	-1.7	-1.2	-0.4	-2.9	-1.2
Severe depression (siblings)	0.9	1.0	3.2	-0.5	-0.7	-1.0	0.8	0.3	-1.6	-1.8	0.3
Supplements: Glucosamine	0.9	1.1	3.5	0.1	0.8	1.1	1.2	1.2	0.9	1.9	-0.1
Prospective memory result	0.9	1.1	3.3	0.8	1.6	1.8	0.1	-0.1	0.9	1.3	-0.5
Impedance of arm (left)	0.9	4.1	9.9	-1.9	-2.0	-2.5	-0.5	-0.7	-3.1	-2.8	0.7
Exposure to tobacco smoke at home	0.9	1.0	3.3	0.1	-0.3	-1.4	-1.2	1.8	0.6	0.7	-0.6
Ever highly irritable/argumentative for 2 days	0.9	1.0	5.8	0.3	-0.7	-1.0	0.1	2.4	-0.1	-0.7	0.5
Handedness (chirality/laterality): Left-handed	0.9	1.1	2.3	0.5	0.6	0.4	1.5	0.4	1.3	1.3	1.4
Back pain experienced in last month	0.9	1.2	4.0	-0.5	-1.4	-2.0	0.0	0.6	-1.0	0.6	1.4
Basal metabolic rate	0.9	4.7	12.6	1.8	2.6	3.5	1.4	0.6	2.5	2.5	0.6
Age started oral contraceptive pill	0.9	1.1	4.8	0.0	1.0	0.9	0.4	-0.3	0.3	1.2	2.2
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	5.3	-0.3	0.8	0.3	-0.3	0.5	-0.6	1.3	2.3
Bipolar Disorder (2011)	0.8	0.7	2.6	0.2	-0.4	-0.1	-1.2	-0.8	-0.4	-0.9	-1.6
Body Mass Index (BMI) (2010)	0.8	1.1	3.6	1.6	0.3	-0.5	0.3	1.9	0.6	1.3	0.5
LDL Cholesterol	0.8	1.2	1.8	-1.2	-1.3	-1.0	-1.4	-1.3	-1.2	-0.7	0.3
Blood Platelet Count	0.8	9.0	17.1	-4.0	-3.3	-3.4	-4.1	-2.8	-2.6	-0.9	-1.2
Hearing difficulty/problems: Yes	0.8	1.2	3.8	1.0	1.3	0.8	-0.3	0.6	1.9	1.3	0.7
Qualifications: None of the above	0.8	1.8	5.9	-0.9	-1.5	-1.8	-2.4	0.7	-0.8	-0.6	-0.7
Impedance of arm (right)	0.8	3.8	6.9	-1.8	-2.2	-2.6	-1.0	-0.8	-2.6	-2.6	0.6
Father’s age at death	0.8	1.0	2.9	1.4	1.3	1.7	0.1	1.3	0.0	0.3	0.3
Worrier / anxious feelings	0.8	1.6	4.6	0.9	0.9	0.4	0.9	2.0	1.1	0.4	2.1
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	2.4	1.1	1.5	1.3	1.5	1.0	0.6	0.2	0.9
Number of full brothers	0.8	1.0	5.6	-0.2	0.5	-0.5	1.2	-0.0	-2.4	0.4	-0.5
Number of children fathered	0.8	0.9	2.1	-0.8	-1.3	-0.9	-0.2	-0.0	-1.1	-1.5	0.6
Medication: Seretide 50 evohaler	0.8	0.9	3.5	-0.1	0.5	0.9	-0.8	-0.2	-0.5	-1.4	-1.9
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.5	0.4	1.4	1.6	0.2	-0.8	0.6	1.1	0.4
Supplements: Vitamin C	0.8	0.9	2.5	-0.7	-0.9	-1.6	0.7	1.2	-0.5	-0.9	0.7
Long-standing illness, disability or infirmity	0.8	1.2	3.5	-0.4	-1.3	-1.9	-0.2	0.4	-1.6	-1.1	0.8
Commuting to job workplace: Cycle	0.8	1.0	2.5	0.8	-0.5	-1.2	1.5	0.5	-0.6	-1.6	0.3
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	4.2	2.0	0.3	0.0	0.1	-0.6	1.1	1.5	0.4
Alcohol drinker status: Previous	0.8	0.9	3.7	1.0	0.2	0.8	-0.7	1.9	0.2	0.1	1.0
Neuroticism (Nagel 2018)	0.7	1.6	2.9	0.8	1.7	0.9	1.5	1.6	0.7	1.3	1.3
Irritable Bowel Disease (IBD)	0.7	1.6	4.4	1.3	-1.2	-2.1	1.8	-0.8	0.2	-1.0	0.5
Average weekly spirits intake	0.7	0.9	2.3	1.2	0.4	0.4	-0.2	0.7	1.5	0.5	1.4
Fed-up feelings	0.7	1.3	3.8	0.0	1.1	-0.1	1.2	1.6	-0.4	0.8	2.0
Stomach or abdominal pain in last month	0.7	0.8	3.5	-0.3	-0.7	-1.3	0.3	0.3	-0.6	-0.4	1.9
Sitting height	0.7	4.8	8.8	1.4	2.7	3.0	2.6	0.5	2.4	2.7	0.5
Had menopause	0.7	0.9	3.7	0.8	0.8	0.6	0.7	0.9	0.6	0.7	1.9
Noisy workplace	0.7	0.9	4.8	-0.6	-0.2	-0.7	-0.7	2.2	-0.3	0.7	-0.6
Breastfed as a baby	0.7	0.9	2.9	-1.0	-0.1	-0.1	-0.1	-1.7	-1.4	-1.0	-0.3
Glaucoma (self-reported)	0.7	0.8	1.6	-1.1	-1.3	-1.3	-0.3	-0.2	-1.2	-0.7	-0.4
Forced vital capacity (FVC), Best measure	0.7	2.7	7.0	0.6	2.4	2.6	0.9	-1.6	0.7	1.3	-1.7
Body fat percentage	0.7	2.8	5.7	-1.9	-1.9	-2.2	-0.3	-0.7	-2.4	-0.8	1.9
Leg fat percentage (right)	0.7	2.6	5.4	-1.6	-1.7	-2.3	-0.0	-0.7	-1.9	-0.4	2.3
Migraine (self-reported)	0.7	0.9	3.1	0.8	0.4	0.0	0.5	1.2	-0.2	1.7	1.3
Overall health rating	0.7	1.5	7.2	0.3	-0.1	-1.3	-0.3	1.1	0.2	1.3	2.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.9	1.1	0.4	0.6	1.7	0.5	0.1	1.2	-0.1
Arm fat-free mass (left)	0.7	3.6	7.3	1.6	2.2	2.7	1.0	0.4	2.6	2.4	0.5
Unable to work because of sickness or disability	0.7	0.9	1.6	1.3	0.9	0.9	0.6	0.9	1.0	0.6	1.0
Depressed Affect (Nagel 2018)	0.6	1.3	3.9	0.4	0.7	-0.5	1.4	2.0	-0.0	1.0	1.6
Fasting Glucose	0.6	0.7	1.8	-1.1	-1.0	-0.4	-1.2	0.1	0.2	-1.4	-0.2
Ever had hysterectomy (womb removed)	0.6	0.7	2.6	0.6	-0.2	-0.7	-1.6	0.6	-0.2	0.8	0.8
Diabetes (mother)	0.6	0.8	2.4	1.6	0.7	1.1	0.6	0.3	1.0	0.9	0.4
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.3	-0.7	-0.8	-1.3	0.4	0.0	-1.5	-0.7	-0.2
Chronic bronchitis/emphysema (father)	0.6	0.7	2.6	-1.6	0.3	0.6	0.2	-1.0	0.1	-0.0	-1.1
Past tobacco smoking	0.6	1.0	1.9	0.0	1.0	1.2	1.4	1.1	-0.2	1.4	0.8
Mouth/teeth dental problems	0.6	0.9	3.2	0.3	0.6	1.8	0.8	0.5	0.5	1.1	-1.2
Alcohol intake versus 10 years previously	0.6	0.9	1.9	0.1	-0.6	-1.4	-1.1	1.1	-1.2	0.6	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	2.7	0.6	0.3	-0.3	-1.1	0.9	1.0	1.7	-0.0
Gout (self-reported)	0.6	0.8	2.1	-1.2	-1.0	-1.3	0.4	0.1	-1.5	-0.1	-0.4
Qualifications: College or University degree	0.6	1.8	5.0	0.9	1.6	2.2	2.1	-1.0	0.2	-0.5	0.2
Medication for pain relief, constipation, heartburn	0.6	1.1	4.8	0.5	0.9	2.2	0.6	-0.7	1.2	-0.2	-0.6
Medication: Ibuprofen	0.6	0.7	2.8	0.2	-0.8	-1.1	-1.7	-0.2	0.5	0.9	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	1.9	-0.7	0.4	0.5	1.1	-0.8	0.3	0.7	-1.4
Smoking status: Previous	0.6	0.9	2.8	0.2	-1.0	-1.0	-0.9	-0.6	0.1	-1.7	-0.9
Average weekly red wine intake	0.6	0.9	5.7	1.1	0.2	-0.1	0.5	2.4	0.4	-0.1	0.3
Friendships satisfaction	0.6	0.7	2.9	0.6	-0.4	-0.3	-1.2	0.4	1.7	0.2	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	3.3	1.2	0.1	-1.2	0.7	0.7	-0.1	0.1	1.8
Commuting to job workplace: Public transport	0.6	0.7	3.9	-0.9	0.2	0.2	0.7	-0.7	0.0	-0.1	2.0
Ever smoked	0.6	1.1	2.9	0.2	-0.8	-0.8	-1.1	-1.3	-0.0	-1.7	-1.4
Leg fat percentage (left)	0.6	2.3	4.6	-1.7	-1.6	-2.1	0.2	-0.5	-1.9	-0.3	2.1
Ever depressed for a whole week	0.6	0.8	2.2	0.5	-0.3	-1.2	-0.8	1.1	-0.4	-1.5	-0.4
Myopia	0.6	0.9	2.3	-0.1	0.8	0.7	0.6	0.0	1.5	1.5	1.0
Crohns Disease (2017)	0.5	1.0	3.8	0.4	-1.2	-2.0	0.8	-0.3	0.3	-0.9	1.1
Ovarian Cancer	0.5	0.6	1.0	0.3	0.8	1.0	1.0	0.7	0.4	0.9	-1.0
Mean Putamen Volume	0.5	0.5	1.3	0.4	0.2	0.7	1.1	-0.8	-0.3	-0.5	-1.1
Waist Hip Ratio (WHR)	0.5	2.4	7.2	-0.4	-2.6	-2.7	-1.1	-0.7	-1.3	-0.4	0.9
Trunk fat percentage	0.5	2.1	4.7	-1.8	-1.6	-1.6	-0.2	-0.7	-2.2	-0.8	1.7
Hair/balding pattern: Pattern 3	0.5	0.7	2.8	-1.3	-0.0	0.6	-0.5	-1.7	0.1	0.2	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	3.0	-0.5	0.3	0.7	1.7	-1.0	-0.0	-0.5	0.2
Mouth/teeth dental problems: Dentures	0.5	0.8	3.1	-0.9	-0.8	-1.1	-1.8	-0.5	-0.6	-0.4	0.2
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.7	-0.6	-0.3	-0.6	0.0	-1.1	-0.0	-1.6	0.0
Headache pain in last month	0.5	0.8	2.3	-0.5	-1.0	-1.5	-1.5	0.6	-0.7	-0.1	0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.5	1.4	1.1	0.7	0.2	1.2	-0.7	0.7	-0.2	-0.5
Age at first live birth	0.5	1.0	4.3	-0.0	-0.2	1.0	-0.3	-1.2	0.7	-0.6	-2.1
Chest pain or discomfort	0.5	0.6	2.5	-0.0	-0.2	-1.2	-0.1	0.6	-1.6	-0.1	0.9
Ever had bowel cancer screening	0.5	0.6	1.6	-0.0	-0.4	-0.7	0.2	1.1	-1.3	-0.2	1.1
Qualifications: nursing, teaching	0.5	0.7	2.9	0.7	1.2	0.6	1.7	-0.4	0.3	0.6	0.5
Mineral and other dietary supplements	0.5	0.6	1.7	-0.5	0.3	-0.2	-0.4	-1.3	-0.8	-1.1	0.8
Smoking status: Current	0.5	0.8	1.8	-1.1	-0.4	-0.5	-1.3	-1.0	-0.3	-1.0	-0.7
Miserableness	0.5	0.8	2.8	0.8	-0.4	-1.5	0.5	1.7	-0.5	0.1	0.3
Medication: Paracetamol	0.5	0.8	2.3	-0.8	-0.9	-1.5	-0.4	-0.2	-0.9	-1.1	0.1
Alcohol drinker status: Never	0.5	0.6	1.9	1.4	0.5	0.5	0.7	0.0	0.9	1.2	-0.2
Risk taking	0.5	0.7	4.6	-0.9	0.2	0.2	-0.1	0.1	-0.5	-0.0	2.1
Depression (Nagel 2018)	0.4	0.6	2.0	0.9	0.5	-0.3	1.4	0.4	-0.2	-0.1	1.1
Schizophrenia (2018)	0.4	0.9	1.9	1.1	-1.3	-1.4	0.6	-0.6	1.0	-0.9	0.3
Major Depression (MDD)	0.4	0.4	1.1	0.7	0.9	-0.3	-0.1	1.0	0.7	0.3	-0.6
Verbal and Numeric Reasoning (VNR)	0.4	0.9	2.3	1.4	0.9	0.7	0.3	0.9	0.9	1.5	0.4
Breast Cancer	0.4	0.9	2.3	-0.0	-1.0	-0.9	-1.1	1.5	0.3	0.0	1.4
Prostate Cancer	0.4	0.5	2.7	1.6	0.9	0.6	0.3	-0.2	0.5	0.1	-0.2
Crohns Disease (2012)	0.4	0.6	1.9	0.1	-0.7	-0.9	1.4	-0.3	0.2	0.1	1.2
Primary Biliary Cirrhosis	0.4	0.5	1.8	0.6	0.7	0.9	1.4	-0.6	0.3	-0.2	-0.3
Schizophrenia (2014)	0.4	0.9	2.4	0.9	-1.2	-0.9	-0.2	-0.7	1.0	-1.5	0.3
Height	0.4	7.6	20.7	2.2	3.6	4.5	1.3	1.4	2.9	3.2	0.6
Respiratory disease	0.4	0.8	3.4	-0.0	0.9	1.0	1.0	-1.9	0.2	0.0	0.8
Lung FVC	0.4	1.8	5.5	-1.3	1.9	1.6	-0.5	-0.3	-0.3	-0.9	-2.4
Chronotype (morning person)	0.4	0.9	2.7	-1.0	-1.0	-1.5	0.4	0.0	-0.2	0.0	1.6
Hair Pigment	0.4	12.8	19.8	3.8	4.0	4.0	1.9	4.0	3.7	4.5	1.8
Tanning	0.4	4.6	10.2	-0.7	-3.1	-3.1	-0.8	-0.2	-2.2	-3.2	1.0
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	0.8	0.4	0.9	0.4	0.8	0.4	-0.8	-0.7	0.8
Medication for hormone replacement therapy	0.4	0.4	0.9	0.7	0.9	0.4	0.6	0.1	0.9	0.6	0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.1	1.1	0.6	-0.2	0.5	0.9	-0.7	0.0	1.1
Qualifications: CSEs or equivalent	0.4	0.5	1.3	1.0	-0.4	-1.1	0.5	0.1	0.7	-0.7	0.4
Serious illness, injury or assault to yourself	0.4	0.5	2.0	0.6	0.3	0.4	1.4	0.0	0.7	-0.5	0.6
Financial difficulties in last 2 years	0.4	0.5	1.0	0.4	0.6	0.4	0.7	-1.0	1.0	0.8	0.5
Arm fat percentage (right)	0.4	1.7	4.9	-1.6	-1.3	-1.2	-0.3	-0.8	-2.2	-0.7	1.4
Standing height	0.4	4.0	9.2	1.6	2.5	3.0	1.9	0.4	2.4	1.9	0.9
Tense / ‘highly strung’	0.4	0.6	2.4	0.5	0.4	-0.1	-0.7	1.5	0.1	-0.1	1.1
Hair/balding pattern: Pattern 4	0.4	0.9	2.4	-0.2	-0.7	-1.4	-0.0	-1.1	-1.1	-1.6	0.3
Eye problems/disorders: None of the above	0.4	0.5	2.1	-0.6	0.1	0.1	-0.5	1.1	-0.4	-1.5	0.2
Medication: Omeprazole	0.4	0.4	1.3	-0.7	0.3	0.3	-0.2	-0.1	-0.6	1.0	1.1
Knee pain experienced in last month	0.4	0.6	1.4	0.0	-1.1	-1.2	-0.5	0.7	-1.0	0.5	-0.3
Arm fat percentage (left)	0.4	1.6	5.1	-1.5	-1.1	-1.1	0.0	-0.6	-2.3	-0.6	1.4
Commuting to job workplace: Walk	0.4	0.4	1.0	0.6	-0.8	-0.9	0.4	1.0	-0.1	-0.8	0.1
Asthma (self-reported)	0.4	0.8	1.9	0.1	0.7	1.2	1.1	-1.4	-0.3	-0.1	1.0
Osteoporosis (self-reported)	0.4	0.5	1.4	0.5	-0.0	-0.4	0.7	-0.3	1.1	-0.6	1.2
Average weekly champagne plus white wine intake	0.4	0.5	2.6	-0.0	-0.2	1.0	0.3	-1.6	-0.0	-0.8	-0.1
Wears glasses or contact lenses	0.4	0.4	1.3	0.0	-0.8	-1.2	-1.1	0.4	0.3	0.3	0.2
Mother’s age at death	0.4	0.5	2.0	-0.2	-0.1	0.5	0.3	-0.9	-1.4	-0.8	-0.0
Eye problems/disorders: Glaucoma	0.4	0.4	1.0	-0.2	-0.9	-0.5	-0.5	1.0	0.4	0.7	-0.8
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.4	0.4	-0.4	-0.8	-0.8	0.8	-1.2	-0.2	-0.2
Average weekly beer plus cider intake	0.4	0.5	1.3	1.0	0.9	0.3	0.4	0.7	1.1	0.6	-0.1
Bipolar Disorder (2018)	0.3	0.4	0.7	-0.7	-0.6	-0.6	-0.5	-0.8	-0.8	-0.7	-0.1
Bipolar Disorder or Schizophrenia	0.3	0.8	2.1	0.4	-1.4	-1.5	0.1	-1.0	0.3	-1.1	0.1
Schizophrenia vs Biploar Disorder	0.3	0.4	2.1	0.3	-0.0	0.1	1.4	0.0	-0.6	-0.2	0.7
Worry (Nagel 2018)	0.3	0.6	3.1	0.2	0.6	0.2	-0.1	1.8	0.2	0.3	1.2
Reaction Time	0.3	0.5	1.6	0.2	-0.8	-1.3	-0.4	0.2	0.3	-1.1	-0.7
Triglycerides	0.3	0.6	3.2	-0.2	0.3	0.6	0.4	-0.6	0.5	0.1	-1.8
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.2	0.6	-0.6	-0.4	-1.1	0.0	0.5	-0.6	-0.7
Blood Red Count	0.3	3.3	8.6	-1.9	-2.9	-2.2	-0.8	-0.8	-2.1	-1.8	0.5
Type 2 Diabetes (T2D) (2018)	0.3	0.5	1.4	0.2	-0.6	-0.5	1.2	1.1	0.2	0.8	0.5
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.5	0.4	0.9	-0.3	0.3	1.2	0.5	0.6	0.6
Medication: Metformin	0.3	0.4	1.2	0.4	-0.8	-0.3	-0.7	1.1	-0.1	0.4	-0.9
Pack years adult smoking proportion	0.3	0.5	1.1	-1.0	0.1	-0.8	-1.1	-0.0	0.9	-0.6	0.2
Current tobacco smoking	0.3	0.5	1.5	-0.7	-0.1	-0.1	-1.2	-0.8	-0.0	-1.0	-0.5
Nervous feelings	0.3	0.6	2.8	-0.0	0.4	0.5	-0.6	1.7	-0.0	0.6	0.8
Diabetes (self-reported)	0.3	0.4	1.0	-0.6	-1.0	-0.6	-0.0	0.9	-0.7	-0.4	-0.2
Weight	0.3	1.2	2.8	0.3	1.0	1.6	1.1	0.0	0.8	1.7	1.3
Asthma	0.3	0.6	1.2	-0.0	0.5	0.8	1.0	-1.1	-0.4	-0.3	1.1
Hypothyroidism/myxoedema (self-reported)	0.3	0.6	1.7	-0.5	-0.7	-1.3	-0.1	0.1	-1.3	-1.0	-0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.9	-0.5	1.0	0.9	-0.6	-0.0	-0.2	-0.5	-0.5
Neck or shoulder pain in last month	0.3	0.4	1.3	-0.1	0.5	0.2	1.1	-0.6	-0.9	0.8	-0.1
Medication: Allopurinol	0.3	0.4	1.7	-0.1	0.1	-0.2	1.0	0.4	-0.4	1.3	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.4	-1.2	0.4	0.9	0.7	-0.2	-0.4	-0.1	0.2
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.3	0.6	-0.0	0.1	-1.1	0.1	1.0	0.1	-0.3
Pain experienced in last month	0.3	0.6	1.9	0.2	1.0	1.4	0.9	-0.7	0.4	-0.1	0.1
Supplements: Calcium	0.3	0.3	0.9	0.6	0.2	0.6	-0.1	-0.9	0.2	-0.7	0.0
Hypothyroidism (self reported)	0.2	0.5	1.4	-0.6	-0.2	-0.5	1.0	-0.8	-1.2	-0.4	0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.7	0.4	0.4	-0.0	-0.4	-0.3	0.7	-0.2	0.8
Diabetes (father)	0.2	0.3	1.3	0.3	-0.1	0.7	-1.1	-0.3	-0.5	0.2	0.2
Hand grip strength (right)	0.2	0.6	2.2	-1.3	-0.3	-0.0	-0.5	-1.5	-0.2	-0.3	-0.5
Relative age voice broke	0.2	0.2	0.6	0.5	0.2	0.2	0.6	0.5	-0.6	-0.7	-0.2
Medication: Levothyroxine sodium	0.2	0.4	1.7	0.3	0.4	-0.4	0.9	0.6	-0.3	-0.2	1.3
Trunk fat mass	0.2	0.7	2.6	-1.1	-0.6	-0.3	0.4	-0.4	-1.1	0.1	1.6
Waist circumference	0.2	0.6	1.6	-0.5	-1.2	-0.9	0.1	-0.1	-0.7	0.9	1.3
Hearing difficulty/problems with background noise	0.2	0.3	1.8	-0.2	-0.1	-0.2	-1.4	-0.0	-0.3	-0.5	-0.6
Hip circumference	0.2	0.7	1.6	0.3	0.8	0.7	1.2	0.4	0.4	1.2	1.2
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.5	-0.1	-0.2	0.4	0.8	-1.2	-0.6	-0.7	-0.4
Lung cancer (father)	0.2	0.2	1.6	-0.1	0.1	0.4	-0.1	-0.0	-0.2	1.3	0.2
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.5	0.7	-0.1	0.1	0.6	0.0	-0.6	-0.3	0.4
Comparative body size at age 10	0.2	0.6	3.2	-0.7	-0.9	-0.1	-0.7	0.2	-0.1	-1.8	-0.1
Wheeze or whistling in the chest in last year	0.2	0.4	1.5	-0.7	-0.3	-0.4	0.2	-0.2	-1.2	-0.9	0.7
Whole body fat mass	0.2	0.8	3.0	-1.1	-0.7	-0.6	0.3	-0.4	-1.1	0.2	1.7
Leg fat mass (right)	0.2	0.8	4.3	-0.9	-0.5	-0.6	0.4	-0.3	-0.5	0.7	2.1
Alcohol intake frequency.	0.2	0.5	1.4	0.2	-1.2	-0.8	0.1	1.0	-0.2	0.5	0.7
Leg pain on walking	0.2	0.2	0.8	0.0	0.2	0.1	-0.0	-0.5	0.8	0.9	-0.1
Diabetes diagnosed by doctor	0.2	0.3	1.7	0.2	-0.5	-0.5	0.3	1.3	-0.3	0.5	-0.2
Ever taken oral contraceptive pill	0.2	0.2	0.6	0.5	0.1	-0.1	-0.5	-0.8	-0.0	0.4	-0.4
Number of operations (self-reported)	0.2	0.3	1.2	0.8	0.8	1.1	0.1	-0.4	0.2	0.1	-0.0
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.6	-0.0	0.2	-0.4	-0.1	0.7	0.8	-0.1	-0.4
Fractured/broken bones in last 5 years	0.2	0.3	1.2	1.1	-0.2	-0.1	0.2	-0.2	0.5	-0.7	-0.1
Pack years of smoking	0.2	0.3	0.8	-0.7	0.2	-0.7	-0.8	0.1	0.9	-0.4	-0.1
Leg fat mass (left)	0.2	0.7	3.6	-0.9	-0.4	-0.4	0.6	-0.2	-0.4	0.8	1.9
Alzheimer’s Disease (in father)	0.1	0.2	0.6	0.7	0.1	0.6	0.3	0.1	-0.1	0.4	-0.4
HDL Cholesterol	0.1	0.2	0.4	0.5	0.1	0.4	0.7	-0.5	0.4	-0.1	-0.6
Hand grip strength (left)	0.1	0.3	1.2	-0.9	0.1	0.3	-0.1	-1.1	-0.0	-0.2	0.5
Townsend deprivation index at recruitment	0.1	0.1	0.3	0.5	0.4	0.6	0.2	-0.2	0.3	-0.1	0.0
Body mass index (BMI)	0.1	0.3	0.9	-0.4	-0.1	0.2	0.2	-0.3	-0.5	0.8	1.0
Alcohol usually taken with meals	0.1	0.2	0.7	0.5	-0.2	-0.0	0.8	-0.0	-0.7	-0.1	0.7
Arm fat mass (right)	0.1	0.5	1.9	-0.7	0.1	0.4	0.3	-0.5	-0.8	0.7	1.4
Medication: Paracetamol	0.1	0.1	0.4	-0.2	0.5	-0.1	0.0	0.6	-0.3	-0.0	0.4
Shortness of breath walking on level ground	0.1	0.2	0.5	0.4	-0.1	-0.5	-0.7	-0.1	0.7	0.0	0.2
Pulse rate, automated reading	0.1	0.5	2.0	0.4	0.5	0.4	0.0	0.3	0.7	1.4	-0.8
Comparative height size at age 10	0.1	0.7	2.0	0.4	0.6	1.0	0.3	-1.1	0.8	-0.4	-1.4
Suffer from ‘nerves’	0.1	0.1	0.4	-0.3	0.7	0.3	-0.1	-0.1	-0.3	0.2	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.3	0.7	0.2	0.8	0.7	0.6	0.2	0.7	0.2	-0.2
Arm fat mass (left)	0.1	0.6	2.2	-0.8	-0.1	0.2	0.3	-0.5	-1.0	0.5	1.5
BMI	0.0	0.2	0.8	-0.2	0.5	0.6	0.4	0.0	0.3	0.9	0.2

Hub : Genes

ARHGAP42

Models

Trait associations