TWAS
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Traits
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Medication: Simvastatin
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chr16:56,749,994-57,261,146
Best TWAS P=8.94e-08 · Best GWAS P=8.94e-08 conditioned to 1
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Lung Adenocarcinoma
CETP
0.06
0.04
lasso
1
0.04
2.8e-05
-5.3
5.3
8.9e-08
-1
0
1
TRUE
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
CETP
0.07
0.08
lasso
1
0.07
7.8e-08
-5.3
5.3
8.9e-08
-1
0
1
FALSE