Best TWAS P=2.24e-08 · Best GWAS P=8.14e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | HPR | 0.72 | 0.60 | lasso | 7 | 0.61 | 6.9e-94 | 5.4 | 5.4 | 7.5e-08 | 1.00 | 0.00 | 1.00 | FALSE |
| 2 | METSIM | Adipose | DHX38 | 0.08 | 0.06 | lasso | 7 | 0.09 | 4.5e-13 | -4.8 | 5.3 | 1.0e-07 | 0.54 | 0.05 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | HPR | 0.82 | 0.49 | lasso | 3 | 0.47 | 3.4e-16 | 5.4 | 5.4 | 5.6e-08 | 1.00 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | HP | 0.60 | 0.42 | lasso | 5 | 0.41 | 3.8e-50 | 5.4 | 5.5 | 3.8e-08 | 1.00 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | HPR | 0.75 | 0.56 | lasso | 4 | 0.56 | 6.1e-76 | 5.4 | 5.3 | 8.9e-08 | 1.00 | 0.00 | 1.00 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TXNL4B | 0.44 | 0.29 | lasso | 4 | 0.29 | 3.2e-33 | 5.4 | 5.6 | 2.2e-08 | 0.99 | 0.00 | 1.00 | TRUE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | HP | 0.05 | 0.04 | blup | 53 | 0.04 | 9.8e-05 | 4.6 | -5.6 | 2.3e-08 | -0.66 | 0.09 | 0.88 | FALSE |